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Gene: Clcnka (chloride channel, voltage-sensitive Ka) Mus musculus
Symbol: Clcnka
Name: chloride channel, voltage-sensitive Ka
Description: Predicted to have voltage-gated chloride channel activity. Involved in regulation of body fluid levels and renal inner medulla development. Localizes to basolateral plasma membrane. Is expressed in inner ear and metanephros. Used to study nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in Bartter disease type 4b and sensorineural hearing loss. Orthologous to human CLCNKA (chloride voltage-gated channel Ka).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C75963; chloride channel K1; chloride channel Ka; chloride channel protein ClC-Ka; CLC-K1; Clcnk1; putative basolateral cTAL chloride channel ClC-Ka
Homo sapiens (human) : CLCNKA (chloride voltage-gated channel Ka)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcnka (chloride voltage-gated channel Ka)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLCNKA (chloride voltage-gated channel Ka)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcnka (chloride voltage-gated channel Ka)
Heterocephalus glaber (naked mole-rat) : Clcnka (chloride voltage-gated channel Ka)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4141,384,610 - 141,398,724 (-)EnsemblGRCm38mm10GRCm38
GRCm384141,384,611 - 141,398,706 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374140,940,526 - 140,954,621 (-)NCBIGRCm37mm9NCBIm37
MGSCv364140,656,686 - 140,670,775 (-)NCBImm8
MGSCv364139,138,024 - 139,141,158 (-)NCBImm8
Celera4143,203,482 - 143,215,208 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Clcnka
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68652
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.