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Gene: Bglap (bone gamma carboxyglutamate protein) Mus musculus
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Symbol: Bglap
Name: bone gamma carboxyglutamate protein
Description: Predicted to have calcium ion binding activity and hydroxyapatite binding activity. Involved in cellular response to BMP stimulus. Localizes to the cytoplasm and extracellular region. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Is expressed in several structures, including bone; forelimb; lower jaw; and rib. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bglap1; Bglap2; BGP; bone gamma carboxyglutamate protein 1; bone Gla protein; gamma-carboxyglutamic acid-containing protein; mOC-A; OC; OG1; osteocalcin
Orthologs:
Homo sapiens (human) : BGLAP (bone gamma-carboxyglutamate protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bglap (bone gamma-carboxyglutamate protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bglap (bone gamma-carboxyglutamate protein)
Pan paniscus (bonobo/pygmy chimpanzee) : BGLAP (bone gamma-carboxyglutamate protein)
Canis lupus familiaris (dog) : BGLAP (bone gamma-carboxyglutamate protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bglap (bone gamma-carboxyglutamate protein)
Sus scrofa (pig) : BGLAP (bone gamma-carboxyglutamate protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38388,383,495 - 88,384,466 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37388,187,417 - 88,188,386 (-)NCBIGRCm37mm9NCBIm37
MGSCv36388,469,422 - 88,470,391 (-)NCBImm8
Celera388,423,135 - 88,424,106 (-)NCBICelera
Cytogenetic Map3 F1NCBI
cM Map338.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Bglap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1621634
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.