Efcc1 (EF hand and coiled-coil domain containing 1) - Rat Genome Database
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Gene: Efcc1 (EF hand and coiled-coil domain containing 1) Mus musculus
Analyze
Symbol: Efcc1
Name: EF hand and coiled-coil domain containing 1
RGD ID: 1615914
MGI Page MGI
Description: Orthologous to human EFCC1 (EF-hand and coiled-coil domain containing 1); INTERACTS WITH bisphenol A; carbon nanotube; paracetamol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AB04155; Ccdc48; coiled-coil domain containing 48; coiled-coil domain-containing protein 48; EF-hand and coiled-coil domain-containing protein 1; EF-hand domain-containing protein ENSP00000381169 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,707,577 - 87,739,410 (+)NCBIGRCm39mm39
GRCm39 Ensembl687,707,851 - 87,732,890 (+)Ensembl
GRCm38687,730,590 - 87,762,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,730,869 - 87,755,908 (+)EnsemblGRCm38mm10GRCm38
MGSCv37687,680,863 - 87,705,906 (+)NCBIGRCm37mm9NCBIm37
MGSCv36687,696,510 - 87,699,658 (+)NCBImm8
Celera689,665,461 - 89,690,504 (+)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:12466851   PMID:12477932   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Efcc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,707,577 - 87,739,410 (+)NCBIGRCm39mm39
GRCm39 Ensembl687,707,851 - 87,732,890 (+)Ensembl
GRCm38687,730,590 - 87,762,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,730,869 - 87,755,908 (+)EnsemblGRCm38mm10GRCm38
MGSCv37687,680,863 - 87,705,906 (+)NCBIGRCm37mm9NCBIm37
MGSCv36687,696,510 - 87,699,658 (+)NCBImm8
Celera689,665,461 - 89,690,504 (+)NCBICelera
Cytogenetic Map6D1NCBI
EFCC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3129,001,629 - 129,040,742 (+)EnsemblGRCh38hg38GRCh38
GRCh383129,001,304 - 129,040,742 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373128,720,147 - 128,759,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,231,982 - 130,242,273 (+)NCBINCBI36hg18NCBI36
Celera3127,152,648 - 127,191,825 (+)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3126,106,963 - 126,146,067 (+)NCBIHuRef
CHM1_13128,683,912 - 128,723,015 (+)NCBICHM1_1
Efcc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24120,188,202 - 120,223,464 (+)NCBI
Rnor_6.0 Ensembl4119,633,755 - 119,661,004 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04119,633,214 - 119,663,081 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04184,885,715 - 184,915,192 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,917,925 - 121,945,822 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4109,149,270 - 109,176,624 (+)NCBICelera
Cytogenetic Map4q34NCBI
Efcc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545010,494,407 - 10,523,125 (-)NCBIChiLan1.0ChiLan1.0
EFCC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13133,410,543 - 133,459,445 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v03126,060,648 - 126,100,007 (+)NCBIMhudiblu_PPA_v0panPan3
EFCC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl203,049,673 - 3,087,023 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1203,047,915 - 3,089,138 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Efcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936798148,549 - 167,924 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFCC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1371,505,035 - 71,540,592 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11371,504,832 - 71,538,394 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21379,102,645 - 79,128,367 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFCC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12252,023,814 - 52,066,719 (-)NCBI
ChlSab1.1 Ensembl2252,023,262 - 52,066,700 (-)Ensembl
Efcc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247817,589,756 - 7,625,387 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:665
Count of miRNA genes:319
Interacting mature miRNAs:388
Transcripts:ENSMUST00000032132, ENSMUST00000159570, ENSMUST00000159681, ENSMUST00000159956, ENSMUST00000160743
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000032132   ⟹   ENSMUSP00000032132
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,730,893 - 87,755,908 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159570   ⟹   ENSMUSP00000138649
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,730,869 - 87,755,451 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159681
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,753,522 - 87,754,762 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159956
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,732,809 - 87,751,896 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160743
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,730,869 - 87,734,017 (+)Ensembl
RefSeq Acc Id: NM_001159697   ⟹   NP_001153169
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,707,851 - 87,732,894 (+)NCBI
GRCm38687,730,869 - 87,755,912 (+)NCBI
Celera689,665,461 - 89,690,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506438   ⟹   XP_006506501
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,707,577 - 87,739,410 (+)NCBI
GRCm38687,730,595 - 87,762,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506440   ⟹   XP_006506503
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,707,723 - 87,739,405 (+)NCBI
GRCm38687,730,590 - 87,762,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321691   ⟹   XP_017177180
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,707,729 - 87,739,405 (+)NCBI
GRCm38687,730,595 - 87,762,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255521   ⟹   XP_030111381
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,707,729 - 87,739,405 (+)NCBI
GRCm38687,730,592 - 87,762,428 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001153169   ⟸   NM_001159697
- UniProtKB: Q9JJF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506501   ⟸   XM_006506438
- Peptide Label: isoform X1
- UniProtKB: A0A0A0MQ84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506503   ⟸   XM_006506440
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017177180   ⟸   XM_017321691
- Peptide Label: isoform X2
- UniProtKB: Q9JJF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030111381   ⟸   XM_030255521
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000138649   ⟸   ENSMUST00000159570
RefSeq Acc Id: ENSMUSP00000032132   ⟸   ENSMUST00000032132
Protein Domains
EF-hand

Promoters
RGD ID:6890370
Promoter ID:EPDNEW_M8621
Type:initiation region
Name:Efcc1_1
Description:Mus musculus EF hand and coiled-coil domain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,730,834 - 87,730,894EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3611451 AgrOrtholog
Ensembl Genes ENSMUSG00000068263 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032132 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000138649 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032132 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000159570 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro CCD48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:58229 UniProtKB/Swiss-Prot
MGD MGI:3611451 ENTREZGENE
NCBI Gene 58229 ENTREZGENE
Pfam CCD48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Efcc1 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MQ84 ENTREZGENE, UniProtKB/TrEMBL
  B9EIH1_MOUSE UniProtKB/TrEMBL
  EFCC1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Efcc1  EF hand and coiled-coil domain containing 1  Ccdc48  coiled-coil domain containing 48  Data Merged 737654 PROVISIONAL
2014-09-17 Efcc1  EF hand and coiled-coil domain containing 1  AB041550  hypothetical protein, MNCb-4779  Symbol and/or name change 5135510 APPROVED