Me1 (malic enzyme 1, NADP(+)-dependent, cytosolic) - Rat Genome Database
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Gene: Me1 (malic enzyme 1, NADP(+)-dependent, cytosolic) Mus musculus
Analyze
Symbol: Me1
Name: malic enzyme 1, NADP(+)-dependent, cytosolic
RGD ID: 10890
MGI Page MGI
Description: Is expressed in several structures, including cardiovascular system; central nervous system; cranium; eye; and genitourinary system. Orthologous to human ME1 (malic enzyme 1); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D9Ertd267; D9Ertd267e; malic enzyme, supernatant; Mdh-1; MGC91072; Mod; Mod-; Mod-1; Mod1; NADP-dependent malic enzyme; NADP-ME
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm7049   Gm7329  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,463,416 - 86,577,967 (-)NCBIGRCm39mm39
GRCm39 Ensembl986,463,424 - 86,578,006 (-)Ensembl
GRCm38986,581,363 - 86,695,914 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl986,581,371 - 86,695,953 (-)EnsemblGRCm38mm10GRCm38
MGSCv37986,474,970 - 86,589,947 (-)NCBIGRCm37mm9NCBIm37
MGSCv36987,524,432 - 87,639,643 (-)NCBImm8
MGSCv36986,378,094 - 86,492,941 (-)NCBImm8
Celera983,658,088 - 83,772,920 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(E)-cinnamyl alcohol  (ISO)
(S)-nicotine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis,11-trans-octadecadienoic acid  (EXP)
Actein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldrin  (EXP)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
Bandrowski's base  (ISO)
benazepril  (ISO)
benzbromarone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzoic acid  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
buspirone  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
celastrol  (ISO)
chloroacetaldehyde  (ISO)
chloroethene  (EXP)
chlorohydrocarbon  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
cyclosporin A  (ISO)
daidzein  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP)
diethyl maleate  (EXP)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
equol  (ISO)
ethanol  (EXP,ISO)
eugenol  (ISO)
felbamate  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (ISO)
fipronil  (ISO)
fluoranthene  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
furan  (ISO)
gedunin  (ISO)
genistein  (ISO)
glafenine  (ISO)
glutathione  (ISO)
hexadecanoic acid  (EXP)
hexane  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
hypochlorous acid  (EXP)
ibuprofen  (ISO)
ifosfamide  (ISO)
indinavir  (EXP)
indole-3-methanol  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoeugenol  (ISO)
isoflavones  (ISO)
isotretinoin  (ISO)
L-ethionine  (ISO)
lamivudine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP,ISO)
melatonin  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methyl salicylate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nelfinavir  (EXP)
nickel sulfate  (ISO)
nicotine  (EXP)
ochratoxin A  (ISO)
omeprazole  (ISO)
oxfendazole  (ISO)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenethyl caffeate  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procymidone  (ISO)
propan-2-ol  (ISO)
pyrazinecarboxamide  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
rac-lactic acid  (ISO)
Rebamipide  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
saquinavir  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
stavudine  (EXP)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topiramate  (ISO)
trans-isoeugenol  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin D  (ISO)
zidovudine  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
mitochondrion  (HDA,IBA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:75870   PMID:93520   PMID:198184   PMID:310441   PMID:314952   PMID:447069   PMID:751643   PMID:752545   PMID:828052   PMID:1009575   PMID:1133851   PMID:1203051  
PMID:1235912   PMID:1311971   PMID:1346782   PMID:1450516   PMID:1477475   PMID:1686571   PMID:1797233   PMID:1939220   PMID:1981995   PMID:2138915   PMID:2165966   PMID:2175917  
PMID:2338144   PMID:2383242   PMID:2422116   PMID:2575582   PMID:2576007   PMID:2792009   PMID:2885918   PMID:3082971   PMID:3106151   PMID:3346258   PMID:3541755   PMID:3805042  
PMID:3863747   PMID:4042679   PMID:4353891   PMID:4382005   PMID:4385090   PMID:4558858   PMID:4566335   PMID:4693062   PMID:5021438   PMID:5358144   PMID:5424503   PMID:5496232  
PMID:5520794   PMID:6241468   PMID:6276492   PMID:6328503   PMID:6375655   PMID:6403543   PMID:6457599   PMID:6457600   PMID:6546753   PMID:6735174   PMID:6785912   PMID:6800944  
PMID:6803586   PMID:6812867   PMID:6838491   PMID:6852526   PMID:6929943   PMID:6939921   PMID:7063884   PMID:7138495   PMID:7262549   PMID:7276516   PMID:7295297   PMID:7411019  
PMID:7626889   PMID:7774558   PMID:7774561   PMID:7873877   PMID:7894162   PMID:8034180   PMID:8094303   PMID:8100460   PMID:8187880   PMID:8268653   PMID:8358175   PMID:8380921  
PMID:8406508   PMID:8482578   PMID:8507983   PMID:8672126   PMID:8875889   PMID:8903730   PMID:9501318   PMID:9722956   PMID:10087289   PMID:10349636   PMID:10508511   PMID:10725249  
PMID:10922068   PMID:11042159   PMID:11076861   PMID:11210181   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:17697936   PMID:18287559   PMID:18614015   PMID:18755687   PMID:18802677   PMID:19270708   PMID:19293334   PMID:19334288   PMID:21267068   PMID:21873635   PMID:22154759   PMID:23055941  
PMID:23056418   PMID:23334421   PMID:25402228   PMID:26173780   PMID:26999781   PMID:27480124   PMID:28202838   PMID:31944402   PMID:32325033  


Genomics

Comparative Map Data
Me1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,463,416 - 86,577,967 (-)NCBIGRCm39mm39
GRCm39 Ensembl986,463,424 - 86,578,006 (-)Ensembl
GRCm38986,581,363 - 86,695,914 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl986,581,371 - 86,695,953 (-)EnsemblGRCm38mm10GRCm38
MGSCv37986,474,970 - 86,589,947 (-)NCBIGRCm37mm9NCBIm37
MGSCv36987,524,432 - 87,639,643 (-)NCBImm8
MGSCv36986,378,094 - 86,492,941 (-)NCBImm8
Celera983,658,088 - 83,772,920 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.58NCBI
ME1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl683,210,402 - 83,431,051 (-)EnsemblGRCh38hg38GRCh38
GRCh38683,210,402 - 83,431,078 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37683,920,121 - 84,140,770 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36683,976,827 - 84,197,498 (-)NCBINCBI36hg18NCBI36
Build 34683,977,975 - 84,197,499NCBI
Celera684,353,414 - 84,574,177 (-)NCBI
Cytogenetic Map6q14.2NCBI
HuRef681,148,328 - 81,370,879 (-)NCBIHuRef
CHM1_1684,017,801 - 84,238,482 (-)NCBICHM1_1
Me1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2887,549,043 - 87,660,251 (-)NCBI
Rnor_6.0 Ensembl894,256,839 - 94,368,834 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0894,256,830 - 94,368,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0893,769,078 - 93,863,611 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4891,839,845 - 91,955,917 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1891,860,614 - 91,975,372 (-)NCBI
Celera887,151,761 - 87,246,579 (-)NCBICelera
RH 3.4 Map8999.69RGD
Cytogenetic Map8q31NCBI
Me1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541110,938,944 - 11,065,085 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541110,938,580 - 11,084,171 (-)NCBIChiLan1.0ChiLan1.0
ME1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1684,382,732 - 84,595,701 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl684,382,732 - 84,595,701 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0681,107,569 - 81,320,050 (-)NCBIMhudiblu_PPA_v0panPan3
ME1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1243,624,945 - 43,828,775 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11243,623,413 - 43,793,590 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Me1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365107,425,983 - 7,571,090 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ME1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,794,964 - 82,991,104 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1182,799,878 - 82,989,895 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2193,051,393 - 93,241,425 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1p12NCBI
ME1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1137,889,211 - 8,112,793 (-)NCBI
ChlSab1.1 Ensembl137,887,984 - 8,112,533 (-)Ensembl
Me1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479911,166,398 - 11,382,662 (+)NCBI

Position Markers
D9Mit135  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38986,648,657 - 86,648,794UniSTSGRCm38
MGSCv37986,542,264 - 86,542,401UniSTSGRCm37
Celera983,725,924 - 83,726,069UniSTS
Cytogenetic Map9E3.1UniSTS
cM Map948.0UniSTS
Whitehead Genetic942.6UniSTS
Whitehead_YAC9 UniSTS
RH126686  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38986,581,455 - 86,581,673UniSTSGRCm38
MGSCv37986,475,062 - 86,475,280UniSTSGRCm37
Celera983,658,180 - 83,658,387UniSTS
Cytogenetic Map9E3.1UniSTS
cM Map948.0UniSTS
Whitehead/MRC_RH9898.09UniSTS
D9Ertd305e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38986,651,873 - 86,652,091UniSTSGRCm38
MGSCv37986,545,480 - 86,545,698UniSTSGRCm37
Celera983,729,323 - 83,729,541UniSTS
Cytogenetic Map9E3.1UniSTS
cM Map949.0UniSTS
Me1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E3.1UniSTS
Mod1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38986,581,535 - 86,581,922UniSTSGRCm38
MGSCv37986,475,142 - 86,475,529UniSTSGRCm37
Celera983,658,260 - 83,658,636UniSTS
Cytogenetic Map9E3.1UniSTS
cM Map948.0UniSTS
Mod1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38986,581,535 - 86,582,574UniSTSGRCm38
MGSCv37986,475,142 - 86,476,181UniSTSGRCm37
Celera983,658,260 - 83,659,283UniSTS
Cytogenetic Map9E3.1UniSTS
cM Map948.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95465267888652678Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95653182690531973Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95911710593117252Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95911710593117252Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95946266493462846Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95946266493462846Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95946266493462846Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96224248596242599Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96513390995640755Mouse
1301290Smgd1_msubmucosal gland distribution 1 (mouse)Not determined96592377486695914Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96936046598819654Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
1301475Tnbs1_mtri-nitrobenzene sulfonic acid susceptible 1 (mouse)Not determined98589751087944172Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:375
Count of miRNA genes:312
Interacting mature miRNAs:331
Transcripts:ENSMUST00000034989
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001198933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC159811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV363687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ070715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M26756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034989   ⟹   ENSMUSP00000034989
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl986,581,371 - 86,695,953 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185374   ⟹   ENSMUSP00000140887
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl986,581,406 - 86,687,277 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189847
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl986,613,541 - 86,618,737 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl986,582,686 - 86,618,704 (-)Ensembl
RefSeq Acc Id: NM_001198933   ⟹   NP_001185862
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39986,463,416 - 86,569,330 (-)NCBI
GRCm38986,581,363 - 86,687,277 (-)NCBI
Celera983,658,088 - 83,772,920 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008615   ⟹   NP_032641
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39986,463,416 - 86,577,967 (-)NCBI
GRCm38986,581,363 - 86,695,914 (-)ENTREZGENE
MGSCv37986,474,970 - 86,589,947 (-)RGD
Celera983,658,088 - 83,772,920 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242666   ⟹   XP_011240968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39986,463,427 - 86,577,635 (-)NCBI
GRCm38986,581,374 - 86,695,582 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032641   ⟸   NM_008615
- Peptide Label: isoform 1
- UniProtKB: P06801 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001185862   ⟸   NM_001198933
- Peptide Label: isoform 2
- UniProtKB: P06801 (UniProtKB/Swiss-Prot),   Q3TQP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011240968   ⟸   XM_011242666
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000034989   ⟸   ENSMUST00000034989
RefSeq Acc Id: ENSMUSP00000140887   ⟸   ENSMUST00000185374
Protein Domains
malic   Malic_M

Promoters
RGD ID:6844836
Promoter ID:MM_KWN:58272
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:UC009QXR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36986,581,146 - 86,581,797 (-)MPROMDB
RGD ID:6844828
Promoter ID:MM_KWN:58274
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell
Transcripts:NM_008615,   UC009QXQ.1,   UC009QXS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36986,589,636 - 86,590,136 (-)MPROMDB
RGD ID:8670358
Promoter ID:EPDNEW_M13209
Type:initiation region
Name:Me1_1
Description:Mus musculus malic enzyme 1, NADP(+)-dependent, cytosolic , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13210  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38986,695,781 - 86,695,841EPDNEW
RGD ID:8670360
Promoter ID:EPDNEW_M13210
Type:initiation region
Name:Me1_2
Description:Mus musculus malic enzyme 1, NADP(+)-dependent, cytosolic , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13209  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38986,695,911 - 86,695,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97043 AgrOrtholog
Ensembl Genes ENSMUSG00000032418 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034989 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000140887 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034989 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000185374 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Malic_enzyme_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_N_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_OxRdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17436 UniProtKB/Swiss-Prot
MGD MGI:97043 ENTREZGENE
NCBI Gene 17436 ENTREZGENE
Pfam malic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Me1 PhenoGen
PIRSF PIRSF000106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS MALOXRDTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MALIC_ENZYMES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART malic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malic_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MAOX_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TQP6 ENTREZGENE, UniProtKB/TrEMBL
  Q3TQW1_MOUSE UniProtKB/TrEMBL
  Q61829_MOUSE UniProtKB/TrEMBL
  Q921S3_MOUSE UniProtKB/TrEMBL
  Q99LF5_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9DBF9 UniProtKB/Swiss-Prot