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Gene: Khk (ketohexokinase) Mus musculus
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Symbol: Khk
Name: ketohexokinase
RGD ID: 10837
Description: Exhibits ketohexokinase activity. Involved in fructose metabolic process and regulation of glycogen metabolic process. Localizes to cytoplasm and nucleus. Is expressed in alimentary system; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in essential fructosuria. Orthologous to human KHK (ketohexokinase); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hepatic fructokinase
Orthologs:
Homo sapiens (human) : KHK (ketohexokinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Khk (ketohexokinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Khk (ketohexokinase)
Pan paniscus (bonobo/pygmy chimpanzee) : KHK (ketohexokinase)
Canis lupus familiaris (dog) : KHK (ketohexokinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Khk (ketohexokinase)
Sus scrofa (pig) : KHK (ketohexokinase)
Chlorocebus sabaeus (African green monkey) : KHK (ketohexokinase)
Heterocephalus glaber (naked mole-rat) : Khk (ketohexokinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl530,921,431 - 30,931,248 (+)EnsemblGRCm38mm10GRCm38
GRCm38530,921,436 - 30,931,248 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37531,224,268 - 31,233,619 (+)NCBIGRCm37mm9NCBIm37
MGSCv36531,198,476 - 31,207,827 (+)NCBImm8
Celera528,401,689 - 28,411,041 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Khk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10837
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.