Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pf4 (platelet factor 4) Mus musculus
Symbol: Pf4
Name: platelet factor 4
RGD ID: 735658
Description: Predicted to have CXCR3 chemokine receptor binding activity; chemokine activity; and heparin binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to protozoan. Localizes to collagen-containing extracellular matrix. Is expressed in several structures, including blood vessel; bone marrow; central nervous system; liver; and yolk sac. Orthologous to several human genes including PF4 (platelet factor 4); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Cxcl; Cxcl4; Pf; PF-4; Scyb; Scyb4
Homo sapiens (human) : PF4 (platelet factor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pf4 (platelet factor 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PF4 (platelet factor 4)
Sus scrofa (pig) : LOC100524373 (platelet factor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39590,920,294 - 90,921,242 (+)NCBI
GRCm38590,772,435 - 90,773,383 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,772,435 - 90,773,383 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,201,461 - 91,202,409 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,847,713 - 91,848,583 (+)NCBImm8
Celera588,924,056 - 88,925,004 (+)NCBICelera
Cytogenetic Map5E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pf4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735658
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.