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Gene: Ccnd1 (cyclin D1) Mus musculus
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Symbol: Ccnd1
Name: cyclin D1
Description: Exhibits cyclin-dependent protein serine/threonine kinase regulator activity; protein kinase activity; and protein kinase binding activity. Involved in several processes, including endoplasmic reticulum unfolded protein response; gland development; and positive regulation of mammary gland epithelial cell proliferation. Localizes to the cyclin-dependent protein kinase holoenzyme complex; cytoplasm; and nucleus. Colocalizes with the bicellular tight junction. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); invasive lobular carcinoma; pancreatic cancer (multiple); and von Hippel-Lindau disease. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human CCND1 (cyclin D1); PARTICIPATES IN E-cadherin signaling pathway; G1/S transition pathway; Notch signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-colchicine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI327039; bcl-1; cD1; CycD1; Cyl-1; G1/S-specific cyclin-D1; PRAD1
Orthologs:
Homo sapiens (human) : CCND1 (cyclin D1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccnd1 (cyclin D1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnd1 (cyclin D1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCND1 (cyclin D1)
Canis lupus familiaris (dog) : CCND1 (cyclin D1)
Sus scrofa (pig) : CCND1 (cyclin D1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm387144,929,931 - 144,939,937 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377152,115,836 - 152,125,830 (-)NCBIGRCm37mm9NCBIm37
MGSCv367144,739,321 - 144,749,220 (-)NCBImm8
Celera7144,694,932 - 144,704,928 (-)NCBICelera
Cytogenetic Map7 F5NCBI
cM Map788.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations