Ccnd1 (cyclin D1) - Rat Genome Database

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Gene: Ccnd1 (cyclin D1) Mus musculus
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Symbol: Ccnd1
Name: cyclin D1
RGD ID: 68557
MGI Page MGI
Description: Enables cyclin-dependent protein serine/threonine kinase regulator activity; protein kinase activity; and protein kinase binding activity. Involved in negative regulation of epithelial cell differentiation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; liver regeneration; and mammary gland development. Located in bicellular tight junction; cytoplasm; and nucleus. Part of cyclin D1-CDK4 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal cancer; hematologic cancer (multiple); invasive lobular carcinoma; and von Hippel-Lindau disease. Orthologous to human CCND1 (cyclin D1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI327039; bcl-; bcl-1; cD1; CycD1; Cyl-; Cyl-1; G1/S-specific cyclin-D1; PR; PRAD1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,483,668 - 144,493,568 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,483,668 - 144,493,662 (-)EnsemblGRCm39 Ensembl
GRCm387144,929,931 - 144,939,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,929,931 - 144,939,925 (-)EnsemblGRCm38mm10GRCm38
MGSCv377152,115,836 - 152,125,830 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,739,321 - 144,749,220 (-)NCBIMGSCv36mm8
Celera7144,694,932 - 144,704,928 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoid cystic carcinoma  (ISO)
Aicardi-Goutieres Syndrome 3  (ISO)
angiosarcoma  (ISO)
Animal Mammary Neoplasms  (ISO)
atherosclerosis  (ISO)
B-lymphoblastic leukemia/lymphoma  (IEP)
Bowen's Disease  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
Burns  (ISO)
carcinoma  (ISO)
Cecal Neoplasms  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chronic Hepatitis C  (ISO)
colon adenoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
Endometrial Neoplasms  (ISO)
Esophageal Neoplasms  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (IMP,ISO)
Experimental Neoplasms  (ISO)
genetic disease  (ISO)
Genomic Instability  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatocellular carcinoma  (IEP,ISO)
high grade glioma  (IMP,ISO)
hyperparathyroidism  (ISO)
Hyperplasia  (ISO)
impotence  (ISO)
intellectual disability  (ISO)
Intestinal Polyps  (ISO)
invasive lobular carcinoma  (ISO)
Kidney Neoplasms  (ISO)
leukemia  (ISO)
liver cancer  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
malignant astrocytoma  (ISO)
mantle cell lymphoma  (ISO)
medulloblastoma  (IMP)
multiple myeloma  (ISO)
Myocardial Ischemia  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
non-Hodgkin lymphoma  (ISO)
ovarian carcinoma  (ISO)
pancreatic adenocarcinoma  (ISO)
pancreatic cancer  (IEP,ISO)
pancreatic ductal adenocarcinoma  (ISO)
pancreatic ductal carcinoma  (ISO)
Pancreatic Intraepithelial Neoplasia  (ISO)
pancreatic solid pseudopapillary carcinoma  (ISO)
papilloma  (ISO)
penile benign neoplasm  (ISO)
pre-malignant neoplasm  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (IEP)
Prostatic Neoplasms  (IEP,ISO)
Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Salivary Gland Neoplasms  (ISO)
squamous cell carcinoma  (ISO)
status epilepticus  (ISO)
Stomach Neoplasms  (ISO)
thyroid gland papillary carcinoma  (ISO)
Thyroid Neoplasms  (ISO)
tongue squamous cell carcinoma  (ISO)
transitional cell carcinoma  (IEP,ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
Uterine Cervical Neoplasms  (ISO)
visual epilepsy  (ISO)
von Hippel-Lindau disease  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (ISO)
(+)-Tetrandrine  (ISO)
(-)-Arctigenin  (ISO)
(-)-cotinine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(20R)-protopanaxadiol  (ISO)
(20S)-ginsenoside Rh2  (ISO)
(R)-adrenaline  (ISO)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
(Z)-3-butylidenephthalide  (ISO)
(Z)-ligustilide  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,3-thiazolidine-2,4-dione  (ISO)
1,4-benzoquinone  (ISO)
1,4-dithiothreitol  (ISO)
1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea  (ISO)
1-methyltryptophan  (ISO)
1-monopalmitoylglycerol  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1H-pyrazole  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-Dihydroxybenzophenone  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-hydroxy-17beta-estradiol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-methoxyidazoxan  (ISO)
2-nitrofluorene  (ISO)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5,5'-tetraiodothyroacetic acid  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-aminobenzamide  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methyladenine  (ISO)
3-methylcholanthrene  (EXP)
3-nitropropanoic acid  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitrophenol  (EXP)
4-nitroquinoline N-oxide  (EXP,ISO)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5'-S-methyl-5'-thioadenosine  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (EXP,ISO)
5-formyltetrahydrofolic acid  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5-methoxypsoralen  (EXP)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (ISO)
6-bromoindirubin-3'-oxime  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
9,10-anthraquinone  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetone  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP,ISO)
acrylonitrile  (ISO)
Actein  (ISO)
acteoside  (ISO)
actinomycin D  (EXP)
adenosine  (ISO)
Aeroplysinin 1  (ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
alachlor  (EXP)
aldehydo-D-glucose  (EXP,ISO)
all-trans-acitretin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allose  (ISO)
alpha-naphthoflavone  (ISO)
alpha-Zearalanol  (EXP,ISO)
alternariol  (EXP)
alvocidib  (EXP,ISO)
amitrole  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
amodiaquine  (ISO)
amphibole asbestos  (ISO)
andrographolide  (ISO)
androstane  (EXP)
aniline  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
anthracene  (ISO)
antimony(0)  (ISO)
Antrocin  (ISO)
antroquinonol  (ISO)
arecoline  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arotinoid acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
asiatic acid  (ISO)
astragaloside IV  (EXP)
atrazine  (EXP,ISO)
avermectin  (ISO)
azadirachtin A  (ISO)
bacitracin  (ISO)
bafilomycin A1  (ISO)
baicalein  (EXP,ISO)
baicalin  (ISO)
benzamides  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
benzoic acid  (ISO)
benzophenanthridine  (ISO)
Berbamine  (ISO)
berberine  (ISO)
Besigomsin  (EXP)
beta-carotene  (ISO)
beta-hexachlorocyclohexane  (EXP,ISO)
beta-ionone  (ISO)
beta-naphthoflavone  (ISO)
betalain  (ISO)
betulinic acid  (ISO)
bexarotene  (EXP,ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
BMS-754807  (ISO)
boric acid  (EXP)
boron atom  (ISO)
bortezomib  (ISO)
bosutinib  (ISO)
brassinolide  (ISO)
brazilein  (ISO)
brexpiprazole  (ISO)
brilliant green  (ISO)
bromobenzene  (ISO)
bromodichloromethane  (ISO)
bucladesine  (ISO)
buspirone  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
butyric acid  (ISO)
C.I. Natural Red 20  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcidiol  (ISO)
calciol  (EXP)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
calyculin a  (ISO)
camostat  (EXP)
camptothecin  (EXP)
canertinib  (EXP)
cannabidiol  (EXP,ISO)
capillarisin  (ISO)
capsaicin  (ISO)
captan  (EXP)
carbamate ester  (EXP)
carbamazepine  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carboplatin  (EXP)
carboxy-PTIO  (ISO)
Cardanol  (ISO)
carmustine  (ISO)
Cassine  (ISO)
celastrol  (EXP,ISO)
celecoxib  (EXP,ISO)
ceruletide  (EXP)
chenodeoxycholic acid  (EXP)
CHIR 99021  (ISO)
chlordecone  (EXP)
chlorendic acid  (ISO)
chlorogenic acid  (EXP)
chlorohydrocarbon  (ISO)
chloropicrin  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
cholic acid  (EXP)
choline  (EXP)
chromium(6+)  (EXP,ISO)
chrysene  (EXP)
chrysin 5,7-dimethyl ether  (ISO)
ciglitazone  (EXP,ISO)
Cirsimarin  (ISO)
cisplatin  (EXP,ISO)
clavulone II  (ISO)
clobenpropit  (ISO)
clofarabine  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
clomiphene  (ISO)
clozapine  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (EXP,ISO)
cobimetinib  (ISO)
cocaine  (ISO)
coenzyme Q10  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP,ISO)
corn oil  (ISO)
corticosterone  (ISO)
coumarin  (ISO)
coumarins  (ISO)
coumermycin A1  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (ISO)
crotonaldehyde  (ISO)
cryptolepine  (ISO)
crystal violet  (ISO)
cucurbitacin B  (EXP)
cucurbitacin I  (EXP)
cumene  (EXP)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cycloastragenol  (EXP)
cycloheximide  (ISO)
Cyclopamine  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
cyprodinil  (ISO)
D-glucose  (EXP,ISO)
dabrafenib  (ISO)
dactolisib  (ISO)
daidzein  (ISO)
DAPT  (ISO)
DDE  (ISO)
DDT  (EXP,ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
delta-tocotrienol  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (EXP)
Deoxyschizandrin  (ISO)
depsipeptide  (ISO)
desferrioxamine B  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP,ISO)
diazoxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenziodolium  (ISO)
dibenzoylmethane  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP,ISO)
Didymin  (ISO)
dieckol  (ISO)
dieldrin  (ISO)
diethyl maleate  (EXP,ISO)
diethylstilbestrol  (EXP,ISO)
digitonin  (EXP)
digitoxin  (ISO)
dihydro-beta-erythroidine  (EXP)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
Dinitramine  (EXP)
dioscin  (ISO)
diosgenin  (ISO)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disodium selenite  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
dronedarone  (ISO)
dutasteride  (ISO)
elemental boron  (ISO)
elemental selenium  (ISO)
ellipticine  (ISO)
embelin  (EXP,ISO)
endosulfan  (EXP,ISO)
entinostat  (EXP,ISO)
eriocitrin  (ISO)
eriodictyol  (ISO)
erlotinib hydrochloride  (ISO)
erythrosin B  (ISO)
esculetin  (ISO)
estragole  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethidium  (ISO)
ethosuximide  (ISO)
etoposide  (ISO)
eugenol  (ISO)
everolimus  (ISO)
Evodiamine  (ISO)
farrerol  (ISO)
fenbendazole  (ISO)
fenhexamid  (ISO)
fenofibrate  (EXP,ISO)
ferulic acid  (ISO)
finasteride  (ISO)
fingolimod hydrochloride  (ISO)
flavanones  (ISO)
flavonoids  (ISO)
fludioxonil  (ISO)
flumequine  (EXP)
fluoranthene  (EXP)
fluoxetine  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
formononetin  (ISO)
fosinopril  (EXP)
fulvestrant  (EXP,ISO)
fumonisin B1  (EXP)
furan  (EXP,ISO)
furazolidone  (ISO)
galangin  (ISO)
gamma-aminobutyric acid  (ISO)
gamma-tocopherol  (ISO)
gefitinib  (EXP,ISO)
geldanamycin  (ISO)
gemcitabine  (EXP,ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geraniol  (ISO)
gingerol  (EXP,ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glycitein  (ISO)
glycyrrhizinic acid  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphene oxide  (EXP)
guggulsterone  (EXP,ISO)
GW 4064  (ISO)
haloperidol  (ISO)
herbicide  (ISO)
hesperetin  (ISO)
hesperidin  (ISO)
hexachlorobenzene  (ISO)
hexachlorophene  (ISO)
hexadecanoic acid  (ISO)
hexestrol  (ISO)
histamine  (ISO)
hydrazine  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxyurea  (EXP,ISO)
hyperforin  (ISO)
Hypsiziprenol-A9  (ISO)
ibuprofen  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indole-3-methanol  (ISO)
indolin-2-one  (ISO)
indometacin  (ISO)
inulin  (EXP)
iron atom  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(III) nitrilotriacetate  (ISO)
Isoangustone A  (EXP,ISO)
isoflavones  (ISO)
isopimaric acid  (EXP)
isoprenaline  (EXP)
isoprene  (ISO)
isorhamnetin  (ISO)
isosilybin A  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
juglone  (ISO)
kaempferol  (ISO)
kahweol  (ISO)
ketamine  (ISO)
KN-93  (ISO)
kojic acid  (EXP,ISO)
kurarinol  (EXP,ISO)
L-1,4-dithiothreitol  (ISO)
L-arginine  (EXP)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (ISO)
L-glutamine  (ISO)
L-methionine  (EXP)
L-mimosine  (ISO)
lactacystin  (ISO)
lamivudine  (ISO)
lapatinib  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
leflunomide  (ISO)
leptomycin B  (ISO)
letrozole  (ISO)
LGK974  (ISO)
Licochalcone A  (ISO)
lidocaine  (EXP)
limonin  (EXP)
linsidomine  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (ISO)
LM-1685  (ISO)
lonafarnib  (ISO)
losartan  (EXP)
lovastatin  (ISO)
lupeol  (EXP)
lutein  (ISO)
luteolin  (EXP)
LY294002  (EXP,ISO)
lycopene  (ISO)
Lysocellin  (ISO)
mabuterol  (ISO)
Maduramicin  (EXP)
magnesium atom  (ISO)
Magnolol  (ISO)
malachite green cation  (ISO)
mancozeb  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manumycin A  (ISO)
masoprocol  (ISO)
medroxyprogesterone acetate  (ISO)
MeIQx  (EXP)
melatonin  (ISO)
melittin  (ISO)
memantine  (ISO)
menadione  (ISO)
mestranol  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (ISO)
MK-2206  (ISO)
ML-7  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (EXP)
monocrotaline  (EXP)
Morroniside  (EXP)
myo-inositol hexakisphosphate  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (ISO)
N-methylformamide  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (ISO)
naproxen  (ISO)
naringin  (EXP,ISO)
Neferine  (ISO)
nerolidol  (ISO)
nicardipine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
niclosamide  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrogen dioxide  (EXP)
NMN zwitterion  (ISO)
nonivamide  (ISO)
Nonylphenol  (ISO)
NS-398  (ISO)
O-(chloroacetylcarbamoyl)fumagillol  (ISO)
obeticholic acid  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oleanolic acid  (EXP,ISO)
oligomycin A  (EXP)
omega-6 fatty acid  (ISO)
omeprazole  (ISO)
omethoate  (ISO)
oridonin  (ISO)
orlistat  (ISO)
orphenadrine  (ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (EXP,ISO)
palbociclib  (EXP,ISO)
palmatine  (ISO)
Panduratin A  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parthenolide  (ISO)
PD 0325901  (EXP)
PD173074  (ISO)
pemetrexed  (ISO)
penconazole  (ISO)
pentachlorophenol  (EXP,ISO)
pentobarbital  (ISO)
perflubutane  (EXP)
perfluorododecanoic acid  (EXP)
perfluoroheptanoic acid  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorohexanoic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perindopril  (EXP)
pevonedistat  (ISO)
phenanthrene  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenylbutazone  (ISO)
phenylephrine  (ISO)
phenylhydrazine  (EXP)
phenytoin  (EXP,ISO)
PhIP  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphatidylcholine  (ISO)
pinosylvin  (ISO)
pioglitazone  (EXP,ISO)
piperine  (ISO)
piperonyl butoxide  (EXP,ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
platycodin D  (EXP)
plumbagin  (ISO)
pluronic P-123  (ISO)
Poloxamer  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP,ISO)
potassium iodide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
probenecid  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
promegestone  (ISO)
propiconazole  (ISO)
propofol  (ISO)
propylparaben  (ISO)
prostaglandin E2  (EXP)
prothioconazole  (ISO)
pterostilbene  (EXP,ISO)
PX-866  (ISO)
pyrene  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
quinacrine  (ISO)
quinolone  (ISO)
rac-1-monopalmitoylglycerol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP,ISO)
reactive oxygen species  (ISO)
regorafenib  (ISO)
reparixin  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (EXP)
ribavirin  (ISO)
rifampicin  (EXP)
rimonabant  (ISO)
ritonavir  (ISO)
rosmarinic acid  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
royal jelly  (EXP)
rubitecan  (ISO)
rucaparib  (ISO)
rutin  (EXP)
ruxolitinib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
Salinomycin  (ISO)
SB 203580  (ISO)
SB 415286  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (ISO)
selumetinib  (EXP)
serpentine asbestos  (EXP)
sevoflurane  (ISO)
shikimic acid  (ISO)
Shikonin  (ISO)
sildenafil citrate  (ISO)
silibinin  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
Siomycin A  (ISO)
sirolimus  (ISO)
SM-164  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium cholate  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sorafenib  (EXP,ISO)
soybean oil  (ISO)
spiromesifen  (ISO)
starch  (ISO)
stattic  (ISO)
sterigmatocystin  (ISO)
streptozocin  (EXP)
sulfadimethoxine  (ISO)
sulfasalazine  (EXP,ISO)
sulforaphane  (EXP,ISO)
sulindac  (EXP,ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
sunitinib  (ISO)
syringic acid  (ISO)
syringin  (ISO)
T-2 toxin  (EXP,ISO)
tadalafil  (EXP)
taiwanin C  (EXP)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
Tanshinone I  (ISO)
taurocholic acid  (ISO)
tauroursodeoxycholic acid  (ISO)
temozolomide  (ISO)
Temsirolimus  (ISO)
terephthalic acid  (ISO)
tert-butyl ethyl ether  (ISO)
Tesaglitazar  (ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
tetracaine  (EXP,ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetraphene  (EXP)
thalidomide  (ISO)
thapsigargin  (ISO)
theaflavin  (EXP)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
thioridazine  (ISO)
thiostrepton  (ISO)
thymoquinone  (EXP,ISO)
thyroxine  (ISO)
tipifarnib  (ISO)
titanium dioxide  (ISO)
tocopherol  (ISO)
tofacitinib  (ISO)
tolbutamide  (ISO)
Tomentosin  (ISO)
topotecan  (ISO)
trabectedin  (ISO)
trans-piceid  (EXP)
trans-pinosylvin  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (EXP,ISO)
trimethylarsine oxide  (ISO)
Triptolide  (EXP,ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (EXP,ISO)
Tryptanthrine  (ISO)
tunicamycin  (ISO)
Tylophorine  (ISO)
tyrphostin AG 1478  (EXP,ISO)
umbelliferone  (ISO)
urea  (ISO)
urethane  (EXP,ISO)
ursodeoxycholic acid  (ISO)
ursolic acid  (ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
vemurafenib  (ISO)
vinclozolin  (EXP,ISO)
vinyl carbamate  (EXP)
vismodegib  (EXP)
vitamin E  (ISO)
vitamin K  (ISO)
vorinostat  (EXP,ISO)
warfarin  (ISO)
withaferin A  (ISO)
wogonin  (ISO)
wortmannin  (EXP,ISO)
xanthohumol  (ISO)
XAV939  (ISO)
Y-27632  (ISO)
Yangonin  (EXP)
zearalenone  (EXP,ISO)
zebularine  (ISO)
zerumbone  (ISO)
zidovudine  (ISO)
zinc atom  (EXP,ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zingerone  (ISO)
zoledronic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (ISO)
cell division  (IEA)
cell population proliferation  (IMP)
cellular response to organic substance  (IDA)
DNA damage response  (ISO)
endoplasmic reticulum unfolded protein response  (IDA)
fat cell differentiation  (IDA)
G1/S transition of mitotic cell cycle  (IBA,IDA,ISO,NAS)
lactation  (IGI,IMP)
Leydig cell differentiation  (ISO)
liver development  (ISO)
liver regeneration  (IDA)
mammary gland alveolus development  (IGI,IMP)
mammary gland epithelial cell proliferation  (IGI)
mitotic G1 DNA damage checkpoint signaling  (ISO)
negative regulation of epithelial cell differentiation  (IGI)
negative regulation of neuron apoptotic process  (IMP)
negative regulation of transcription by RNA polymerase II  (IGI,ISO)
neuron differentiation  (IMP)
positive regulation of cell population proliferation  (ISO)
positive regulation of G1/S transition of mitotic cell cycle  (IBA)
positive regulation of G2/M transition of mitotic cell cycle  (ISO)
positive regulation of mammary gland epithelial cell proliferation  (IGI)
positive regulation of protein phosphorylation  (ISO)
re-entry into mitotic cell cycle  (IDA)
regulation of cell cycle  (IDA)
regulation of G1/S transition of mitotic cell cycle  (IGI)
response to calcium ion  (ISO)
response to corticosterone  (ISO)
response to estradiol  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to glucocorticoid  (ISO)
response to iron ion  (ISO)
response to leptin  (ISO)
response to magnesium ion  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to organonitrogen compound  (ISO)
response to steroid hormone  (ISO)
response to UV-A  (ISO)
response to vitamin E  (ISO)
response to X-ray  (ISO)
response to xenobiotic stimulus  (ISO)
Wnt signaling pathway  (IDA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal corpus luteum morphology  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal hematopoietic stem cell morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal lymphopoiesis  (IAGP)
abnormal mammary gland growth during lactation  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal nervous system development  (IAGP)
abnormal nursing  (IAGP)
abnormal reflex  (IAGP)
abnormal retina morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal suckling behavior  (IAGP)
absent Purkinje cell layer  (IAGP)
anemia  (IAGP)
aspiration  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased mammary gland tumor incidence  (IAGP)
decreased total retina thickness  (IAGP)
decreased tumor growth/size  (IAGP)
decreased tumor incidence  (IAGP)
disorganized retina ganglion layer  (IAGP)
disorganized retina layers  (IAGP)
ectopic Purkinje cell  (IAGP)
enlarged spleen  (IAGP)
enlarged testis  (IAGP)
enlarged thymus  (IAGP)
female infertility  (IAGP)
hydrops fetalis  (IAGP)
impaired coordination  (IAGP)
increased body weight  (IAGP)
increased intestinal adenoma incidence  (IAGP)
increased mammary adenocarcinoma incidence  (IAGP)
increased mammary gland tumor incidence  (IAGP)
increased pituitary adenoma incidence  (IAGP)
increased tumor latency  (IAGP)
lactation failure  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
limb grasping  (IAGP)
long incisors  (IAGP)
male infertility  (IAGP)
misaligned incisors  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
pup cannibalization  (IAGP)
reduced cerebellar foliation  (IAGP)
retina hypoplasia  (IAGP)
small cerebellum  (IAGP)
thin retina ganglion layer  (IAGP)
thin ventricular wall  (IAGP)
thymus hyperplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
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2. Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analysis of CD G870A polymorphism, FISH and immunohistochemistry. Bachmann K, etal., J Surg Oncol. 2015 Mar;111(3):316-23. doi: 10.1002/jso.23826. Epub 2014 Dec 2.
3. The role of cyclins and cyclins inhibitors in the multistep process of HPV-associated cervical carcinoma. Bahnassy AA, etal., J Egypt Natl Canc Inst. 2006 Dec;18(4):292-302.
4. Aberrant expression of G1-phase cell cycle regulators in flat and exophytic adenomas of the human colon. Bartkova J, etal., Gastroenterology. 2001 Jun;120(7):1680-8. doi: 10.1053/gast.2001.24880.
5. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Bergsagel PL, etal., Blood. 2005 Jul 1;106(1):296-303. Epub 2005 Mar 8.
6. Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia. Biankin AV, etal., Cancer Res. 2001 Dec 15;61(24):8830-7.
7. Effects of ischemic preconditioning on cyclinD1 expression during early ischemic reperfusion in rats. Cai FG, etal., World J Gastroenterol. 2006 May 14;12(18):2936-40.
8. Oncogenic virus-associated neoplasia: a role for cyclin D1 genotypes influencing the age of onset of disease? Catarino R, etal., Biochem Biophys Res Commun. 2008 May 23;370(1):118-22. Epub 2008 Mar 18.
9. Differential expressions of cyclin D1 associated with better prognosis of cancers of ampulla of Vater. Chang MC, etal., World J Surg. 2007 May;31(5):1135-41. doi: 10.1007/s00268-006-0032-6.
10. CCND1 G870A polymorphism with altered cyclin D1 transcripts expression is associated with the risk of glioma in a Chinese population. Chen X, etal., DNA Cell Biol. 2012 Jun;31(6):1107-13. doi: 10.1089/dna.2011.1521. Epub 2012 Feb 3.
11. Expression of cyclin D1 in endometrial hyperplasia and endometrial carcinoma. Choudhury M and Bansal S, Indian J Pathol Microbiol. 2007 Oct;50(4):708-10.
12. Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors. Christov K, etal., Breast Cancer Res Treat. 2003 Feb;77(3):253-64.
13. Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma. Ciznadija D, etal., Cancer Res. 2011 Oct 1;71(19):6174-83. doi: 10.1158/0008-5472.CAN-11-1031. Epub 2011 Aug 15.
14. Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway involved in the rat bladder carcinogenesis induced by terephthalic acid-calculi. Cui L, etal., Urol Res. 2006 Oct;34(5):321-8. Epub 2006 Jul 29.
15. WNT10A/ß-catenin pathway in tumorigenesis of papillary thyroid carcinoma. Dong T, etal., Oncol Rep. 2017 Aug;38(2):1287-1294. doi: 10.3892/or.2017.5777. Epub 2017 Jul 3.
16. Association of CCND1 overexpression with KRAS and PTEN alterations in specific subtypes of non-small cell lung carcinoma and its influence on patients' outcome. Dragoj M, etal., Tumour Biol. 2015 Nov;36(11):8773-80. doi: 10.1007/s13277-015-3620-y. Epub 2015 Jun 9.
17. Cyclin D1 (CCND1) A870G gene polymorphism modulates smoking-induced lung cancer risk and response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients. Gautschi O, etal., Lung Cancer. 2006 Mar;51(3):303-11. Epub 2006 Jan 10.
18. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences Ge JR, etal., Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007 Sep;36(5):483-7.
19. Cyclin D1, p16(INK) (4A) and p27(Kip1) in pancreatic adenocarcinoma: assessing prognostic implications through quantitative image analysis. Georgiadou D, etal., APMIS. 2014 Dec;122(12):1230-9. doi: 10.1111/apm.12289. Epub 2014 Jul 22.
20. The effect of STAT3 inhibition on status epilepticus and subsequent spontaneous seizures in the pilocarpine model of acquired epilepsy. Grabenstatter HL, etal., Neurobiol Dis. 2014 Feb;62:73-85. doi: 10.1016/j.nbd.2013.09.003. Epub 2013 Sep 16.
21. Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer. Gupta S, etal., Sci Rep. 2015 Nov 19;5:16811. doi: 10.1038/srep16811.
22. Inhibition of tumor growth and metastasis by non-small cell lung cancer cells transfected with cyclin D1-targeted siRNA. Huang H, etal., Oligonucleotides. 2009 Jun;19(2):151-62. doi: 10.1089/oli.2008.0174.
23. Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer. Huynh H, etal., Mol Cancer Ther. 2007 Nov;6(11):2959-66.
24. Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients. Ito M, etal., Clin Immunol. 2010 Jun;135(3):459-65. doi: 10.1016/j.clim.2010.02.002. Epub 2010 Mar 1.
25. MYEOV: a candidate gene for DNA amplification events occurring centromeric to CCND1 in breast cancer. Janssen JW, etal., Int J Cancer. 2002 Dec 20;102(6):608-14.
26. Effect of energy restriction on cell cycle machinery in 1-methyl-1-nitrosourea-induced mammary carcinomas in rats. Jiang W, etal., Cancer Res. 2003 Mar 15;63(6):1228-34.
27. Tissue microarray analyses of G1/S-regulatory proteins in ductal carcinoma in situ of the breast indicate that low cyclin D1 is associated with local recurrence. Jirstrom K, etal., Br J Cancer. 2003 Nov 17;89(10):1920-6.
28. Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells. Joo MK, etal., Int J Oncol. 2015;46(6):2380-8. doi: 10.3892/ijo.2015.2935. Epub 2015 Mar 26.
29. Microarray analysis of gene expression profile in the corpus cavernosum of hypercholesterolemic rats after chronic treatment with PDE5 inhibitor. Jung HG, etal., Life Sci. 2007 Jan 23;80(7):699-708. Epub 2006 Nov 29.
30. Expression of Wnt target genes in solid pseudopapillary tumor of the pancreas: a pilot study. Kang CM, etal., Pancreas. 2009 Mar;38(2):e53-9.
31. Overexpression of ß-Catenin and Cyclin D1 is Associated with Poor Overall Survival in Patients with Stage IA-IIA Squamous Cell Lung Cancer Irrespective of Adjuvant Chemotherapy. Kim Y, etal., J Thorac Oncol. 2016 Dec;11(12):2193-2201. doi: 10.1016/j.jtho.2016.07.021. Epub 2016 Aug 4.
32. Sunitinib Inhibits Breast Cancer Cell Proliferation by Inducing Apoptosis, Cell-cycle Arrest and DNA Repair While Inhibiting NF-κB Signaling Pathways. Korashy HM, etal., Anticancer Res. 2017 Sep;37(9):4899-4909. doi: 10.21873/anticanres.11899.
33. Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. Latasa MU, etal., PLoS One. 2010 Dec 29;5(12):e15690. doi: 10.1371/journal.pone.0015690.
34. Negative effect of cyclin D1 overexpression on recurrence-free survival in stage II-IIIA lung adenocarcinoma and its expression modulation by vorinostat in vitro. Lee E, etal., BMC Cancer. 2015 Dec 17;15:982. doi: 10.1186/s12885-015-2001-7.
35. Expression of cyclin D1 splice variants is differentially associated with outcome in non-small cell lung cancer patients. Li R, etal., Hum Pathol. 2008 Dec;39(12):1792-801. doi: 10.1016/j.humpath.2008.05.008. Epub 2008 Aug 19.
36. [Relationship between the expression of beta-cat, cyclin D1 and c-myc and the occurance and biological behavior of pancreatic cancer]. Li YJ and Ji XR, Zhonghua Bing Li Xue Za Zhi. 2003 Jun;32(3):238-41.
37. Identification of novel predictive markers for the prognosis of pancreatic ductal adenocarcinoma. Luo Y, etal., Hum Pathol. 2013 Jan;44(1):69-76. doi: 10.1016/j.humpath.2012.04.014. Epub 2012 Aug 30.
38. Differential expression of cell cycle regulatory molecules and evidence for a "cyclin switch" during progression of prostate cancer. Maddison LA, etal., Prostate. 2004 Mar 1;58(4):335-44.
39. Cyclin D1 and retinoblastoma susceptibility gene alterations in non-small cell lung cancer. Marchetti A, etal., Int J Cancer. 1998 Jan 19;75(2):187-92.
40. Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck. Matthias C, etal., Clin Cancer Res. 1998 Oct;4(10):2411-8.
41. CCND1- and ERBB2-gene deregulation and PTEN mutation analyses in invasive lobular carcinoma of the breast. Mercapide J, etal., Mol Carcinog. 2002 Sep;35(1):6-12.
42. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
43. MGDs mouse GO annotations MGD data from the GO Consortium
44. MGD IEA MGD IEA
45. Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence. Narayanan BA, etal., Clin Cancer Res. 2007 Oct 1;13(19):5965-73.
46. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
47. Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk. Onay UV, etal., BMC Cancer. 2008 Jan 14;8(1):6.
48. Functional Role of CyclinD1 Polymorphism (G870A) in Modifying Susceptibility and Overall Survival of North Indian Lung Cancer Patients. Pandey A, etal., Tumori. 2017 Dec 1:tj5000707. doi: 10.5301/tj.5000707.
49. Expression of cyclin D1 and Ki-67 in squamous cell carcinoma of the penis. Papadopoulos O, etal., Anticancer Res. 2007 Jul-Aug;27(4B):2167-74.
50. Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis. Parekh P and Rao KV, Cell Biol Int. 2007 Jan;31(1):35-43. Epub 2006 Sep 10.
51. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
52. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
53. Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Pogoriler J, etal., Development. 2006 Oct;133(19):3929-37. doi: 10.1242/dev.02556. Epub 2006 Aug 30.
54. The CCND1 G870A gene polymorphism and leukemia or non-Hodgkin lymphoma risk: a meta-analysis. Qin LY, etal., Asian Pac J Cancer Prev. 2014;15(16):6923-8.
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56. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
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PMID:29466738   PMID:29556338   PMID:29599703   PMID:29632206   PMID:29684311   PMID:29689621   PMID:29859210   PMID:29867344   PMID:29882512   PMID:29899135   PMID:29950673   PMID:29975682  
PMID:29986157   PMID:30037926   PMID:30081710   PMID:30093671   PMID:30201295   PMID:30220628   PMID:30292786   PMID:30333037   PMID:30338292   PMID:30428088   PMID:30459452   PMID:30485816  
PMID:30635284   PMID:30683671   PMID:30685387   PMID:30789911   PMID:30884041   PMID:30914320   PMID:30957234   PMID:30979723   PMID:31024075   PMID:31042497   PMID:31097699   PMID:31199666  
PMID:31260508   PMID:31286143   PMID:31315048   PMID:31345937   PMID:31499015   PMID:31578284   PMID:31604927   PMID:31634485   PMID:31806625   PMID:31845891   PMID:31988190   PMID:32002646  
PMID:32013948   PMID:32043969   PMID:32128839   PMID:32169905   PMID:32244147   PMID:32290105   PMID:32299058   PMID:32453714   PMID:32518258   PMID:32571845   PMID:32631996   PMID:32703236  
PMID:32732898   PMID:32747435   PMID:32877917   PMID:32886109   PMID:32937140   PMID:33048843   PMID:33075808   PMID:33110058   PMID:33155500   PMID:33192541   PMID:33428297   PMID:33436499  
PMID:33448039   PMID:33470495   PMID:33564997   PMID:33580754   PMID:33621399   PMID:33723039   PMID:33804107   PMID:33854232   PMID:33913480   PMID:34032268   PMID:34057742   PMID:34124068  
PMID:34162961   PMID:34246625   PMID:34292881   PMID:34309628   PMID:34321999   PMID:34469723   PMID:34497269   PMID:34514884   PMID:34610275   PMID:34653670   PMID:34746147   PMID:34789782  
PMID:34851661   PMID:34871739   PMID:34878095   PMID:34879283   PMID:34887903   PMID:34928956   PMID:35084365   PMID:35085892   PMID:35521669   PMID:35563756   PMID:35652338   PMID:35902588  
PMID:35917186   PMID:35951005   PMID:36196625   PMID:36218069   PMID:36220812   PMID:36255053   PMID:36269819   PMID:36414671   PMID:36670467   PMID:36899896   PMID:36920550   PMID:36960826  
PMID:37048108   PMID:37171286   PMID:37220402   PMID:37267426   PMID:37311811   PMID:37497597   PMID:37566909   PMID:37684532   PMID:37686246   PMID:37723138   PMID:37751417   PMID:37824328  
PMID:38191655  


Genomics

Comparative Map Data
Ccnd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,483,668 - 144,493,568 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,483,668 - 144,493,662 (-)EnsemblGRCm39 Ensembl
GRCm387144,929,931 - 144,939,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,929,931 - 144,939,925 (-)EnsemblGRCm38mm10GRCm38
MGSCv377152,115,836 - 152,125,830 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,739,321 - 144,749,220 (-)NCBIMGSCv36mm8
Celera7144,694,932 - 144,704,928 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.92NCBI
CCND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,641,156 - 69,654,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,641,156 - 69,654,474 (+)EnsemblGRCh38hg38GRCh38
GRCh371169,455,924 - 69,469,242 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,165,054 - 69,178,423 (+)NCBINCBI36Build 36hg18NCBI36
Build 341169,165,053 - 69,178,422NCBI
Celera1166,752,901 - 66,766,272 (+)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1165,748,357 - 65,761,725 (+)NCBIHuRef
CHM1_11169,338,874 - 69,352,243 (+)NCBICHM1_1
T2T-CHM13v2.01169,658,031 - 69,671,351 (+)NCBIT2T-CHM13v2.0
Ccnd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,518,288 - 209,527,986 (-)NCBIGRCr8
mRatBN7.21200,089,002 - 200,098,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,089,002 - 200,098,602 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,470,197 - 208,479,709 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,556,434 - 215,565,956 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,230,641 - 208,240,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,090,750 - 218,100,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,090,750 - 218,100,325 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,960,136 - 224,969,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,357,235 - 205,366,757 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,510,735 - 205,520,201 (-)NCBI
Celera1197,647,068 - 197,656,590 (-)NCBICelera
Cytogenetic Map1q42NCBI
Ccnd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542216,448,770 - 16,463,300 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542216,449,921 - 16,462,676 (-)NCBIChiLan1.0ChiLan1.0
CCND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2970,605,973 - 70,620,190 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,649,950 - 71,663,325 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01164,737,006 - 64,750,353 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,029,134 - 68,041,553 (+)NCBIpanpan1.1PanPan1.1panPan2
CCND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,501,905 - 48,509,684 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,501,899 - 48,516,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,111,842 - 47,121,415 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01849,179,073 - 49,188,648 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1849,178,951 - 49,189,038 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11848,625,670 - 48,635,233 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01848,211,983 - 48,221,555 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01848,958,012 - 48,967,584 (-)NCBIUU_Cfam_GSD_1.0
Ccnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,527,409 - 4,541,987 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936599973,838 - 983,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
CCND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,621,246 - 3,633,296 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,621,242 - 3,633,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,342,276 - 2,348,167 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,909,616 - 4,922,272 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,907,353 - 4,922,357 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038102,182,953 - 102,196,194 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccnd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476717,469,622 - 17,483,191 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476717,470,310 - 17,483,082 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccnd1
212 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1799
Count of miRNA genes:728
Interacting mature miRNAs:933
Transcripts:ENSMUST00000093962, ENSMUST00000135985
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

Markers in Region
AI327039  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,932,242 - 144,932,375UniSTSGRCm38
MGSCv377152,118,147 - 152,118,280UniSTSGRCm37
Celera7144,697,252 - 144,697,385UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
Whitehead/MRC_RH71476.04UniSTS
UniSTS:235821  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,930,274 - 144,930,481UniSTSGRCm38
MGSCv377152,116,179 - 152,116,386UniSTSGRCm37
Celera7144,695,274 - 144,695,481UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
PMC139749P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,931,652 - 144,932,014UniSTSGRCm38
MGSCv377152,117,557 - 152,117,919UniSTSGRCm37
Celera7144,696,661 - 144,697,023UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
PMC152277P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,940,593 - 144,940,798UniSTSGRCm38
MGSCv377152,126,498 - 152,126,703UniSTSGRCm37
Celera7144,705,598 - 144,705,803UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
BI280117  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,931,217 - 144,931,432UniSTSGRCm38
MGSCv377152,117,122 - 152,117,337UniSTSGRCm37
Celera7144,696,226 - 144,696,441UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
Ccnd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,938,073 - 144,939,648UniSTSGRCm38
MGSCv377152,117,127 - 152,117,587UniSTSGRCm37
MGSCv377152,118,563 - 152,119,973UniSTSGRCm37
Celera7144,703,075 - 144,704,651UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
cM Map772.3UniSTS
cM Map772.3UniSTS
PMC321442P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,937,418 - 144,938,056UniSTSGRCm38
MGSCv377152,123,323 - 152,123,961UniSTSGRCm37
Celera7144,702,420 - 144,703,058UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
PMC98458P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,939,494 - 144,939,693UniSTSGRCm38
MGSCv377152,125,399 - 152,125,598UniSTSGRCm37
Celera7144,704,497 - 144,704,696UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
Cd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38386,995,288 - 86,995,448UniSTSGRCm38
MGSCv37386,799,210 - 86,799,370UniSTSGRCm37
Celera387,020,774 - 87,020,919UniSTS
Celera598,185,350 - 98,186,057UniSTS
Cytogenetic Map5E4UniSTS
cM Map348.0UniSTS
Ccnd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,931,222 - 144,931,682UniSTSGRCm38
MGSCv377152,117,127 - 152,117,587UniSTSGRCm37
Celera7144,696,231 - 144,696,691UniSTS
Cytogenetic Map7F5UniSTS
Ccnd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,932,658 - 144,934,068UniSTSGRCm38
MGSCv377152,118,563 - 152,119,973UniSTSGRCm37
Celera7144,697,670 - 144,699,080UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS
Ccnd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F5UniSTS
cM Map772.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001379248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF212040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF384675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY089102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU600170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S78355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000093962   ⟹   ENSMUSP00000091495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7144,483,668 - 144,493,606 (-)Ensembl
GRCm38.p6 Ensembl7144,929,931 - 144,939,869 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7144,491,032 - 144,491,934 (-)Ensembl
GRCm38.p6 Ensembl7144,937,295 - 144,938,197 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208193
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7144,486,935 - 144,493,662 (-)Ensembl
GRCm38.p6 Ensembl7144,933,198 - 144,939,925 (-)Ensembl
RefSeq Acc Id: NM_001379248   ⟹   NP_001366177
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397144,483,668 - 144,493,568 (-)NCBI
GRCm387144,929,931 - 144,939,831 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007631   ⟹   NP_031657
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397144,483,668 - 144,493,568 (-)NCBI
GRCm387144,929,931 - 144,939,831 (-)NCBI
MGSCv377152,115,836 - 152,125,830 (-)RGD
Celera7144,694,932 - 144,704,928 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_031657   ⟸   NM_007631
- Peptide Label: isoform 2
- UniProtKB: P25322 (UniProtKB/Swiss-Prot),   Q790L7 (UniProtKB/TrEMBL),   Q3TC96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001366177   ⟸   NM_001379248
- Peptide Label: isoform 1
- UniProtKB: Q3TC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000091495   ⟸   ENSMUST00000093962
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P25322-F1-model_v2 AlphaFold P25322 1-295 view protein structure

Promoters
RGD ID:8666299
Promoter ID:EPDNEW_M11181
Type:initiation region
Name:Ccnd1_1
Description:Mus musculus cyclin D1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387144,939,831 - 144,939,891EPDNEW
RGD ID:6848102
Promoter ID:MM_ACW:46637
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney,   Lung
Transcripts:CCND1.BSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367152,118,374 - 152,118,874 (-)MPROMDB
RGD ID:6840799
Promoter ID:MM_KWN:53449
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000064209
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367152,123,631 - 152,125,037 (-)MPROMDB
RGD ID:6840798
Promoter ID:MM_KWN:53450
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_007631
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367152,125,506 - 152,126,237 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88313 AgrOrtholog
Ensembl Genes ENSMUSG00000031071
  ENSMUSG00000070348 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000093962 ENTREZGENE
  ENSMUST00000093962.5 UniProtKB/Swiss-Prot
Gene3D-CATH Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyclin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_C-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclins_cyclin-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12443 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88313 ENTREZGENE
NCBI Gene 12443 ENTREZGENE
PANTHER PTHR10177 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10177:SF67 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cyclin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CCND1 RGD
PhenoGen Ccnd1 PhenoGen
PROSITE CYCLINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CYCLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2M0W7_MOUSE UniProtKB/TrEMBL
  CCND1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TC96 ENTREZGENE, UniProtKB/TrEMBL
  Q790L7 ENTREZGENE, UniProtKB/TrEMBL