Mkln1 (muskelin 1, intracellular mediator containing kelch motifs) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Mkln1 (muskelin 1, intracellular mediator containing kelch motifs) Mus musculus
Analyze
Symbol: Mkln1
Name: muskelin 1, intracellular mediator containing kelch motifs
RGD ID: 734392
MGI Page MGI
Description: Enables identical protein binding activity. Involved in several processes, including cell-matrix adhesion; neurotransmitter receptor transport postsynaptic membrane to endosome; and regulation of cell shape. Located in several cellular components, including cell cortex; nucleoplasm; and ruffle. Is active in GABA-ergic synapse; postsynaptic endosome membrane; and postsynaptic specialization membrane of symmetric synapse. Is expressed in several structures, including alimentary system; heart; limb; nervous system; and sensory organ epithelium. Orthologous to human MKLN1 (muskelin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A130067F06Rik; AU015903; BB154892; muskelin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39631,333,833 - 31,493,744 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl631,375,670 - 31,493,746 (+)EnsemblGRCm39 Ensembl
GRCm38631,398,828 - 31,516,809 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl631,398,735 - 31,516,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv37631,348,828 - 31,459,482 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36631,329,008 - 31,439,645 (+)NCBIMGSCv36mm8
Celera631,385,689 - 31,497,090 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cylindrospermopsin  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diquat  (EXP)
dorsomorphin  (ISO)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
genistein  (ISO)
glafenine  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
propiconazole  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. cDNA cloning of human muskelin and localisation of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6 B1/B2 by physical mapping and FISH. Adams JC and Zhang L, Cytogenet Cell Genet 1999;87(1-2):19-21.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9724633   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12384287   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:15084145   PMID:15489334   PMID:15741177   PMID:16141072   PMID:16141073   PMID:17049906   PMID:17474996   PMID:18710924   PMID:18799693   PMID:21267068   PMID:21482357   PMID:21586270  
PMID:21677750   PMID:21873635   PMID:25372678   PMID:25579817   PMID:25737280   PMID:26496610   PMID:30174115   PMID:32554809   PMID:36417873   PMID:38460002  


Genomics

Comparative Map Data
Mkln1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39631,333,833 - 31,493,744 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl631,375,670 - 31,493,746 (+)EnsemblGRCm39 Ensembl
GRCm38631,398,828 - 31,516,809 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl631,398,735 - 31,516,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv37631,348,828 - 31,459,482 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36631,329,008 - 31,439,645 (+)NCBIMGSCv36mm8
Celera631,385,689 - 31,497,090 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.57NCBI
MKLN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387131,110,094 - 131,496,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7131,110,096 - 131,496,632 (+)EnsemblGRCh38hg38GRCh38
GRCh377130,794,853 - 131,181,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367130,663,175 - 130,831,931 (+)NCBINCBI36Build 36hg18NCBI36
Build 347130,469,892 - 130,638,645NCBI
Celera7125,545,899 - 125,932,352 (+)NCBICelera
Cytogenetic Map7q32.3NCBI
HuRef7125,110,633 - 125,497,059 (+)NCBIHuRef
CHM1_17130,728,553 - 131,115,275 (+)NCBICHM1_1
T2T-CHM13v2.07132,427,607 - 132,814,224 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27130,134,571 - 130,521,037 (+)NCBI
Mkln1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8460,939,239 - 61,095,214 (+)NCBIGRCr8
mRatBN7.2459,815,912 - 60,124,047 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl460,002,464 - 60,123,993 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx464,972,547 - 65,093,857 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0460,888,753 - 61,009,664 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0459,290,700 - 59,412,013 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0458,693,384 - 58,817,924 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl458,693,384 - 58,817,691 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0458,448,153 - 58,570,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4458,475,702 - 58,600,770 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1458,751,831 - 58,876,900 (+)NCBI
Celera455,092,934 - 55,213,778 (+)NCBICelera
Cytogenetic Map4q22NCBI
Mkln1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541036,251,987 - 36,542,802 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541036,251,987 - 36,568,537 (-)NCBIChiLan1.0ChiLan1.0
MKLN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26167,930,262 - 168,320,858 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1719,940,570 - 20,331,104 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07123,075,319 - 123,463,509 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17135,806,585 - 135,976,926 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7135,806,585 - 135,968,032 (+)Ensemblpanpan1.1panPan2
MKLN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1145,636,148 - 5,799,882 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl145,636,162 - 5,799,833 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha145,298,099 - 5,625,705 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0145,374,406 - 5,699,541 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl145,371,337 - 5,699,433 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1145,577,443 - 5,905,031 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0145,322,616 - 5,650,615 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0145,465,309 - 5,793,416 (-)NCBIUU_Cfam_GSD_1.0
Mkln1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511823,841,621 - 24,179,321 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365793,982,296 - 4,150,063 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365793,982,296 - 4,150,071 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MKLN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1817,501,857 - 17,832,503 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11817,493,806 - 17,832,519 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21818,593,094 - 18,776,077 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MKLN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12199,952,000 - 100,123,380 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21100,007,890 - 100,123,139 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660423,255,971 - 3,434,499 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mkln1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247834,900,654 - 5,074,740 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247834,891,874 - 5,074,769 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5682
Count of miRNA genes:983
Interacting mature miRNAs:1476
Transcripts:ENSMUST00000026699, ENSMUST00000130108, ENSMUST00000133182, ENSMUST00000134315, ENSMUST00000134544, ENSMUST00000137621, ENSMUST00000141045, ENSMUST00000142469, ENSMUST00000147614, ENSMUST00000149859, ENSMUST00000150949, ENSMUST00000154954
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144495Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144495Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144495Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse

Markers in Region
AU015903  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,471,007 - 31,471,212UniSTSGRCm38
MGSCv37631,421,007 - 31,421,212UniSTSGRCm37
Celera631,458,616 - 31,458,821UniSTS
Cytogenetic Map6B1-B2UniSTS
Whitehead/MRC_RH6243.02UniSTS
BB154892  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,470,707 - 31,470,838UniSTSGRCm38
MGSCv37631,420,707 - 31,420,838UniSTSGRCm37
Celera631,458,316 - 31,458,447UniSTS
Cytogenetic Map6B1-B2UniSTS
Whitehead/MRC_RH6215.4UniSTS
02.MHAa56e2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,504,074 - 31,504,231UniSTSGRCm38
MGSCv37631,454,074 - 31,454,231UniSTSGRCm37
Celera631,491,682 - 31,491,839UniSTS
Cytogenetic Map6B1-B2UniSTS
Whitehead_YAC6 UniSTS
D5Mit406.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5A1UniSTS
Cytogenetic Map6B1-B2UniSTS
cM Map564.0UniSTS
Whitehead Genetic550.3UniSTS
AU047206  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,412,730 - 31,412,888UniSTSGRCm38
MGSCv37631,362,730 - 31,362,888UniSTSGRCm37
Celera631,399,677 - 31,399,835UniSTS
Cytogenetic Map6B1-B2UniSTS
RH128619  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,507,697 - 31,507,903UniSTSGRCm38
MGSCv37631,457,697 - 31,457,903UniSTSGRCm37
Celera631,495,305 - 31,495,511UniSTS
Cytogenetic Map6B1-B2UniSTS
D4Rat23  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38631,467,661 - 31,467,798UniSTSGRCm38
MGSCv37631,417,661 - 31,417,798UniSTSGRCm37
Celera631,455,270 - 31,455,407UniSTS
Cytogenetic Map6B1-B2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001429318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC024913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC153837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV321114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD550341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF161946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000026699   ⟹   ENSMUSP00000026699
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,670 - 31,493,746 (+)Ensembl
GRCm38.p6 Ensembl631,398,735 - 31,516,811 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130108   ⟹   ENSMUSP00000123048
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,466,329 - 31,484,903 (+)Ensembl
GRCm38.p6 Ensembl631,489,394 - 31,507,968 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133182
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,771 - 31,396,371 (+)Ensembl
GRCm38.p6 Ensembl631,398,836 - 31,419,436 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134315
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,763 - 31,447,824 (+)Ensembl
GRCm38.p6 Ensembl631,398,828 - 31,470,889 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,780 - 31,407,802 (+)Ensembl
GRCm38.p6 Ensembl631,398,845 - 31,430,867 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,764 - 31,412,952 (+)Ensembl
GRCm38.p6 Ensembl631,398,829 - 31,436,017 (+)Ensembl
Ensembl Acc Id: ENSMUST00000141045
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,445,055 - 31,469,628 (+)Ensembl
GRCm38.p6 Ensembl631,468,120 - 31,492,693 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,407,651 - 31,451,311 (+)Ensembl
GRCm38.p6 Ensembl631,430,716 - 31,474,376 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149859
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,469,556 - 31,484,782 (+)Ensembl
GRCm38.p6 Ensembl631,492,621 - 31,507,847 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150949
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,407,617 - 31,466,346 (+)Ensembl
GRCm38.p6 Ensembl631,430,682 - 31,489,411 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154954
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,794 - 31,410,066 (+)Ensembl
GRCm38.p6 Ensembl631,398,859 - 31,433,131 (+)Ensembl
Ensembl Acc Id: ENSMUST00000200915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,453,798 - 31,457,409 (+)Ensembl
GRCm38.p6 Ensembl631,476,863 - 31,480,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202577
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl631,375,780 - 31,381,407 (+)Ensembl
GRCm38.p6 Ensembl631,398,845 - 31,404,472 (+)Ensembl
RefSeq Acc Id: NM_013791   ⟹   NP_038819
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39631,375,763 - 31,486,417 (+)NCBI
GRCm38631,398,828 - 31,509,482 (+)NCBI
MGSCv37631,348,828 - 31,459,482 (+)RGD
Celera631,385,689 - 31,497,090 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321605   ⟹   XP_017177094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39631,375,734 - 31,493,744 (+)NCBI
GRCm38631,398,848 - 31,516,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255437   ⟹   XP_030111297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39631,375,783 - 31,493,744 (+)NCBI
GRCm38631,398,848 - 31,516,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166200   ⟹   XP_036022093
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39631,333,833 - 31,493,744 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166201   ⟹   XP_036022094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39631,375,803 - 31,493,744 (+)NCBI
Sequence:
RefSeq Acc Id: NP_038819   ⟸   NM_013791
- UniProtKB: O89050 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177094   ⟸   XM_017321605
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030111297   ⟸   XM_030255437
- Peptide Label: isoform X3
Ensembl Acc Id: ENSMUSP00000123048   ⟸   ENSMUST00000130108
Ensembl Acc Id: ENSMUSP00000026699   ⟸   ENSMUST00000026699
RefSeq Acc Id: XP_036022093   ⟸   XM_036166200
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036022094   ⟸   XM_036166201
- Peptide Label: isoform X3
Protein Domains
CTLH   LisH   Muskelin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O89050-F1-model_v2 AlphaFold O89050 1-735 view protein structure

Promoters
RGD ID:6839645
Promoter ID:MM_KWN:45474
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4
Transcripts:OTTMUST00000034972,   OTTMUST00000041377,   OTTMUST00000041379,   OTTMUST00000041381,   OTTMUST00000041383,   UC009BGC.1,   UC009BGD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36631,348,606 - 31,349,106 (+)MPROMDB
RGD ID:6889270
Promoter ID:EPDNEW_M8082
Type:multiple initiation site
Name:Mkln1_1
Description:Mus musculus muskelin 1, intracellular mediator containing kelchmotifs , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38631,398,848 - 31,398,908EPDNEW
RGD ID:6839647
Promoter ID:MM_KWN:45479
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver
Transcripts:OTTMUST00000034973
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36631,446,129 - 31,446,629 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1351638 AgrOrtholog
Ensembl Genes ENSMUSG00000025609 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026699 ENTREZGENE
  ENSMUST00000026699.15 UniProtKB/Swiss-Prot
  ENSMUST00000130108.3 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CTLH_C UniProtKB/Swiss-Prot
  CTLH_complex_component UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gal_Oxase/kelch_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Muskelin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:27418 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1351638 ENTREZGENE
NCBI Gene 27418 ENTREZGENE
PANTHER MUSKELIN UniProtKB/Swiss-Prot
  MUSKELIN UniProtKB/Swiss-Prot
  MUSKELIN UniProtKB/TrEMBL
  MUSKELIN UniProtKB/TrEMBL
Pfam Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_3 UniProtKB/Swiss-Prot
  Muskelin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mkln1 PhenoGen
PROSITE CTLH UniProtKB/Swiss-Prot
  LISH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50965 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F6UW85_MOUSE UniProtKB/TrEMBL
  MKLN1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TNJ2_MOUSE UniProtKB/TrEMBL
  Q3UWT3_MOUSE UniProtKB/TrEMBL