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Gene: Nos2 (nitric oxide synthase 2, inducible) Mus musculus
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Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Description: Exhibits several functions, including arginine binding activity; coenzyme binding activity; and heme binding activity. Involved in several processes, including negative regulation of macromolecule metabolic process; nitric oxide biosynthetic process; and response to bacterium. Localizes to the cortical cytoskeleton and perinuclear region of cytoplasm. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); hypertension (multiple); malaria; pulmonary tuberculosis; and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; enteric nervous system; genitourinary system; and hemolymphoid system gland. Orthologous to human NOS2 (nitric oxide synthase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: i-NOS; inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNOS; MAC-NOS; macrophage NOS; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; NOS type II; Nos-2; NOS-II; Nos2a; peptidyl-cysteine S-nitrosylase NOS2
Orthologs:
Homo sapiens (human) : NOS2 (nitric oxide synthase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nos2 (nitric oxide synthase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nos2 (nitric oxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS2 (nitric oxide synthase 2)
Canis lupus familiaris (dog) : NOS2 (nitric oxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos2 (nitric oxide synthase 2)
Sus scrofa (pig) : NOS2 (nitric oxide synthase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381178,920,787 - 78,960,226 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,734,361 - 78,773,626 (+)NCBIGRCm37mm9NCBIm37
MGSCv361178,737,054 - 78,776,319 (+)NCBImm8
Celera1188,553,193 - 88,592,780 (+)NCBICelera
Cytogenetic Map11 B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model