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Gene: Cldn1 (claudin 1) Mus musculus
Symbol: Cldn1
Name: claudin 1
Description: Exhibits identical protein binding activity. Involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell junction maintenance; and establishment of skin barrier. Localizes to several cellular components, including apical plasma membrane; bicellular tight junction; and lateral plasma membrane. Is expressed in several structures, including alimentary system; axial skeleton; brain; metanephros; and skin. Human ortholog(s) of this gene implicated in Crohn's disease and atopic dermatitis. Orthologous to human CLDN1 (claudin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI596271; claudin-1
Homo sapiens (human) : CLDN1 (claudin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cldn1 (claudin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn1 (claudin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN1 (claudin 1)
Canis lupus familiaris (dog) : CLDN1 (claudin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn1 (claudin 1)
Sus scrofa (pig) : CLDN1 (claudin 1)
Chlorocebus sabaeus (African green monkey) : CLDN1 (claudin 1)
Heterocephalus glaber (naked mole-rat) : Cldn1 (claudin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1626,356,642 - 26,371,841 (-)EnsemblGRCm38mm10GRCm38
GRCm381626,356,645 - 26,371,839 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371626,356,737 - 26,371,925 (-)NCBIGRCm37mm9NCBIm37
MGSCv361626,272,000 - 26,287,188 (-)NCBImm8
Celera1626,899,939 - 26,915,115 (-)NCBICelera
Cytogenetic Map16B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cldn1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68627
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.