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Gene: Cldn1 (claudin 1) Mus musculus
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Symbol: Cldn1
Name: claudin 1
Description: Exhibits identical protein binding activity. Involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell junction maintenance; and establishment of skin barrier. Localizes to several cellular components, including apical plasma membrane; bicellular tight junction; and lateral plasma membrane. Is expressed in several structures, including alimentary system; axial skeleton; brain; metanephros; and skin. Human ortholog(s) of this gene implicated in Crohn's disease and atopic dermatitis. Orthologous to human CLDN1 (claudin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI596271; claudin-1
Orthologs:
Homo sapiens (human) : CLDN1 (claudin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cldn1 (claudin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn1 (claudin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN1 (claudin 1)
Canis lupus familiaris (dog) : CLDN1 (claudin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn1 (claudin 1)
Sus scrofa (pig) : CLDN1 (claudin 1)
Chlorocebus sabaeus (African green monkey) : CLDN1 (claudin 1)
Heterocephalus glaber (naked mole-rat) : Cldn1 (claudin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1626,356,642 - 26,371,841 (-)EnsemblGRCm38mm10GRCm38
GRCm381626,356,645 - 26,371,839 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371626,356,737 - 26,371,925 (-)NCBIGRCm37mm9NCBIm37
MGSCv361626,272,000 - 26,287,188 (-)NCBImm8
Celera1626,899,939 - 26,915,115 (-)NCBICelera
Cytogenetic Map16B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cldn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68627
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.