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Gene: Hdac3 (histone deacetylase 3) Mus musculus
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Symbol: Hdac3
Name: histone deacetylase 3
Description: Exhibits chromatin DNA binding activity; protein deacetylase activity; and transcription factor binding activity. Involved in several processes, including histone H4-K12 deacetylation; positive regulation of cold-induced thermogenesis; and regulation of gene expression. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; exocrine gland; oocyte; and retina. Used to study endometriosis. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human HDAC3 (histone deacetylase 3); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW537363; HD3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma
Orthologs:
Homo sapiens (human) : HDAC3 (histone deacetylase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac3 (histone deacetylase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac3 (histone deacetylase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC3 (histone deacetylase 3)
Canis lupus familiaris (dog) : HDAC3 (histone deacetylase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac3 (histone deacetylase 3)
Sus scrofa (pig) : HDAC3 (histone deacetylase 3)
Chlorocebus sabaeus (African green monkey) : HDAC3 (histone deacetylase 3)
Heterocephalus glaber (naked mole-rat) : Hdac3 (histone deacetylase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1837,935,844 - 37,955,016 (-)EnsemblGRCm38mm10GRCm38
GRCm381837,936,971 - 37,955,015 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371838,096,625 - 38,114,642 (-)NCBIGRCm37mm9NCBIm37
MGSCv361838,062,953 - 38,080,909 (-)NCBImm8
Celera1839,280,295 - 39,298,302 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1819.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hdac3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731327
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.