Hdac3 (histone deacetylase 3) - Rat Genome Database

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Gene: Hdac3 (histone deacetylase 3) Chinchilla lanigera
Analyze
Symbol: Hdac3
Name: histone deacetylase 3
RGD ID: 8789124
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); cyclin binding (ortholog); INVOLVED IN cellular response to fluid shear stress (ortholog); cellular response to mechanical stimulus (ortholog); cellular response to parathyroid hormone stimulus (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute kidney failure (ortholog); Anaphylaxis (ortholog); colorectal cancer (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541512,138,870 - 12,154,234 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541512,138,520 - 12,154,234 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to fluid shear stress  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to parathyroid hormone stimulus  (ISO)
circadian regulation of gene expression  (ISO)
histone deacetylation  (ISO)
histone H3 deacetylation  (ISO)
histone H4 deacetylation  (ISO)
histone H4-K12 deacetylation  (ISO)
negative regulation of cardiac muscle cell differentiation  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of interleukin-1 production  (ISO)
negative regulation of JNK cascade  (ISO)
negative regulation of myotube differentiation  (ISO)
negative regulation of protein export from nucleus  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein ubiquitination  (ISO)
positive regulation of TOR signaling  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of type B pancreatic cell apoptotic process  (ISO)
protein deacetylation  (ISO)
regulation of circadian rhythm  (ISO)
regulation of mitotic cell cycle  (ISO)
regulation of multicellular organism growth  (ISO)
regulation of protein stability  (ISO)
response to dexamethasone  (ISO)
response to nutrient levels  (ISO)
response to xenobiotic stimulus  (ISO)
spindle assembly  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Hdac3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541512,138,870 - 12,154,234 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541512,138,520 - 12,154,234 (+)NCBIChiLan1.0ChiLan1.0
HDAC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5141,620,876 - 141,636,849 (-)EnsemblGRCh38hg38GRCh38
GRCh385141,620,881 - 141,636,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375141,000,448 - 141,016,416 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,980,627 - 140,996,607 (-)NCBINCBI36hg18NCBI36
Build 345140,980,626 - 140,996,596NCBI
Celera5137,077,171 - 137,093,151 (-)NCBI
Cytogenetic Map5q31.3NCBI
HuRef5136,145,083 - 136,160,930 (-)NCBIHuRef
CHM1_15140,433,725 - 140,449,704 (-)NCBICHM1_1
Hdac3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,070,024 - 38,088,073 (-)NCBIGRCm39mm39
GRCm39 Ensembl1838,068,897 - 38,088,069 (-)Ensembl
GRCm381837,936,971 - 37,955,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1837,935,844 - 37,955,016 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,096,625 - 38,114,642 (-)NCBIGRCm37mm9NCBIm37
MGSCv361838,062,953 - 38,080,909 (-)NCBImm8
Celera1839,280,295 - 39,298,302 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1819.81NCBI
Hdac3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21829,770,637 - 29,789,850 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1831,073,058 - 31,094,303 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01831,073,057 - 31,094,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01830,764,344 - 30,782,387 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,857,209 - 30,875,986 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11830,883,855 - 30,902,632 (-)NCBI
Celera1829,414,681 - 29,434,382 (-)NCBICelera
Cytogenetic Map18p11NCBI
HDAC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15143,094,406 - 143,110,322 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5143,094,406 - 143,110,322 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05136,981,790 - 136,997,786 (-)NCBIMhudiblu_PPA_v0panPan3
HDAC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,583,283 - 36,598,121 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,583,283 - 36,597,682 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha233,635,234 - 33,650,086 (-)NCBI
ROS_Cfam_1.0237,037,462 - 37,052,393 (-)NCBI
UMICH_Zoey_3.1234,112,034 - 34,126,890 (-)NCBI
UNSW_CanFamBas_1.0234,923,559 - 34,938,422 (-)NCBI
UU_Cfam_GSD_1.0235,730,823 - 35,745,706 (-)NCBI
Hdac3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,956,557 - 150,972,579 (+)NCBI
SpeTri2.0NW_00493650412,530,546 - 12,546,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2143,273,191 - 143,287,387 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12143,273,188 - 143,287,421 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22149,475,764 - 149,490,030 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HDAC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12344,246,296 - 44,263,127 (-)NCBI
Vero_WHO_p1.0NW_02366603433,589,487 - 33,606,357 (+)NCBI
Hdac3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624774845,970 - 864,080 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000021159   ⟹   ENSCLAP00000020958
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541512,138,870 - 12,154,234 (+)Ensembl
RefSeq Acc Id: XM_005380723   ⟹   XP_005380780
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541512,138,870 - 12,154,234 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380724   ⟹   XP_005380781
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541512,138,586 - 12,154,230 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380725   ⟹   XP_005380782
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541512,138,520 - 12,154,230 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005380780 (Get FASTA)   NCBI Sequence Viewer  
  XP_005380781 (Get FASTA)   NCBI Sequence Viewer  
  XP_005380782 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005380782   ⟸   XM_005380725
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005380781   ⟸   XM_005380724
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005380780   ⟸   XM_005380723
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000020958   ⟸   ENSCLAT00000021159


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014357 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000020958 ENTREZGENE
Ensembl Transcript ENSCLAT00000021159 ENTREZGENE
NCBI Gene Hdac3 ENTREZGENE