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Gene: Car8 (carbonic anhydrase 8) Mus musculus
Symbol: Car8
Name: carbonic anhydrase 8
Description: Predicted to have carbonate dehydratase activity and zinc ion binding activity. Involved in phosphatidylinositol-mediated signaling. Localizes to cytoplasm. Used to study cerebellar ataxia, mental retardation and dysequlibrium syndrome. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome. Is expressed in several structures, including alimentary system; brain; ear; genitourinary system; and respiratory system. Orthologous to human CA8 (carbonic anhydrase 8); INTERACTS WITH 1,1-dichloroethene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW546993; CA-RP VIII; CA-VIII; Ca8; Cals; Cals1; carbonic anhydrase VIII; carbonic anhydrase-like sequence 1; carbonic anhydrase-related protein; Carp; wdl
Homo sapiens (human) : CA8 (carbonic anhydrase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ca8 (carbonic anhydrase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ca8 (carbonic anhydrase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CA8 (carbonic anhydrase 8)
Canis lupus familiaris (dog) : CA8 (carbonic anhydrase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ca8 (carbonic anhydrase 8)
Sus scrofa (pig) : CA8 (carbonic anhydrase 8)
Chlorocebus sabaeus (African green monkey) : CA8 (carbonic anhydrase 8)
Heterocephalus glaber (naked mole-rat) : Ca8 (carbonic anhydrase 8)
more info ...
Related Pseudogenes: Gm17987  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl48,143,362 - 8,239,041 (-)EnsemblGRCm38mm10GRCm38
GRCm3848,141,493 - 8,239,041 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3748,068,640 - 8,166,188 (-)NCBIGRCm37mm9NCBIm37
MGSCv3647,613,848 - 7,709,581 (-)NCBImm8
MGSCv3648,068,640 - 8,166,188 (-)NCBImm8
Celera48,024,484 - 8,115,866 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Car8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312314
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.