Eln (elastin) - Rat Genome Database

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Gene: Eln (elastin) Mus musculus
Analyze
Symbol: Eln
Name: elastin
RGD ID: 733666
MGI Page MGI
Description: Exhibits extracellular matrix binding activity. Involved in several processes, including regulation of actin filament polymerization; skeletal muscle tissue development; and stress fiber assembly. Localizes to elastic fiber. Is expressed in several structures, including alimentary system; cardiovascular system; cranium; limb; and respiratory system. Used to study aortic valve disease; essential hypertension; and supravalvular aortic stenosis. Human ortholog(s) of this gene implicated in several diseases, including Williams-Beuren syndrome; aortic disease (multiple); autoimmune disease (multiple); cutis laxa (multiple); and retinal disease (multiple). Orthologous to human ELN (elastin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI385707; AI480567; E030024M20Rik; tropoelastin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395134,731,449 - 134,776,300 (-)NCBIGRCm39mm39
GRCm39 Ensembl5134,731,447 - 134,776,177 (-)Ensembl
GRCm385134,702,595 - 134,747,368 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,702,593 - 134,747,323 (-)EnsemblGRCm38mm10GRCm38
MGSCv375135,178,466 - 135,223,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv365134,987,223 - 135,031,881 (-)NCBImm8
Celera5131,710,617 - 131,755,279 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Anetoderma  (ISO)
aortic aneurysm  (ISO)
aortic valve disease  (IEA)
aortic valve stenosis  (ISO)
atrioventricular septal defect  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
autosomal dominant cutis laxa  (ISO)
autosomal dominant cutis laxa 1  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
bladder neck obstruction  (ISO)
Buschke-Ollendorff syndrome  (ISO)
chronic obstructive pulmonary disease  (ISO)
congenital diaphragmatic hernia  (ISO)
cutis laxa  (ISO)
dermatitis herpetiformis  (ISO)
diabetic retinopathy  (ISO)
Diaphragmatic Hernia  (ISO)
essential hypertension  (IEA)
exfoliation syndrome  (ISO)
Experimental Diabetes Mellitus  (ISO)
facioscapulohumeral muscular dystrophy  (ISO)
genetic disease  (ISO)
Hypertelorism  (ISO)
hypertension  (ISO)
intestinal volvulus  (ISO)
intracranial aneurysm  (ISO)
Kawasaki disease  (IEP)
Kuhnt-Junius degeneration  (ISO)
Lichen Sclerosus et Atrophicus  (ISO)
liver cirrhosis  (ISO)
macular degeneration  (ISO)
melanoma  (ISO)
Myocardial Ischemia  (ISO)
Neurodevelopmental Disorders  (ISO)
photosensitivity disease  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
polyarteritis nodosa  (ISO)
polymyositis  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
primary open angle glaucoma  (ISO)
pseudoxanthoma elasticum  (ISO)
psoriasis  (ISO)
pterygium  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (ISO)
silicosis  (ISO)
Sunburn  (ISO)
Supravalvar Aortic Stenosis, Eisenberg Type  (ISO)
supravalvular aortic stenosis  (IEA,ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
temporal arteritis  (ISO)
thoracic aortic aneurysm  (ISO)
thromboangiitis obliterans  (ISO)
Urinary Incontinence, Stress  (ISO)
varicose veins  (ISO)
Volvulus Of Midgut  (ISO)
Williams-Beuren syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
alachlor  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
beta-aminopropionitrile  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
C60 fullerene  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
chloroprene  (ISO)
choline  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP)
cycloheximide  (ISO)
D-penicillamine  (ISO)
dexamethasone  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
fenamidone  (EXP)
flurbiprofen  (EXP)
folic acid  (EXP)
furan  (ISO)
griseofulvin  (EXP)
hydralazine  (ISO)
hydrogen sulfide  (EXP)
isoprenaline  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP)
losartan  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (EXP)
nickel atom  (EXP,ISO)
nickel sulfate  (EXP)
nitrofen  (ISO)
nitroglycerin  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
palbociclib  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
radicicol  (ISO)
rotenone  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
tetrachloromethane  (ISO)
tetrathiomolybdate(2-)  (ISO)
titanium dioxide  (EXP,ISO)
Trapidil  (ISO)
tremolite asbestos  (EXP)
triclosan  (ISO)
triptonide  (EXP)
Y-27632  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
1. Alvira CM, etal., Am J Pathol. 2011 Mar;178(3):1210-20. doi: 10.1016/j.ajpath.2010.11.054.
2. Baccarani-Contri M, etal., Eur J Histochem. 1994;38(2):111-23.
3. Bernstein EF, etal., J Invest Dermatol. 1994 Aug;103(2):182-6.
4. Bodvarsson S, etal., Scand J Immunol. 1993 Dec;38(6):546-50.
5. Bokarewa M, etal., Pathol Biol (Paris). 1996 Apr;44(4):254-8.
6. Colburn KK, etal., J Investig Med. 2003 Mar;51(2):104-9.
7. DeSilva U, etal., Genome Res 1999 May;9(5):428-36.
8. Dridi SM, etal., Am J Med Genet. 1999 Nov 19;87(2):134-8.
9. Ewart AK, etal., J Clin Invest. 1994 Mar;93(3):1071-7.
10. Farrell AM, etal., J Eur Acad Dermatol Venereol. 2001 May;15(3):212-7.
11. Feinmesser M, etal., Am J Dermatopathol. 2002 Apr;24(2):108-17.
12. Gillot JM, etal., J Rheumatol. 1997 Apr;24(4):677-82.
13. Giro MG, etal., J Invest Dermatol. 1992 Aug;99(2):129-37.
14. Gray MA, etal., Urology. 2008 Jun;71(6):1214-9. doi: 10.1016/j.urology.2007.11.054. Epub 2008 Feb 15.
15. Guarino N, etal., J Pediatr Surg. 2002 Sep;37(9):1253-7.
16. Hadj-Rabia S, etal., Orphanet J Rare Dis. 2013 Feb 25;8:36. doi: 10.1186/1750-1172-8-36.
17. Hernandez MR Invest Ophthalmol Vis Sci. 1992 Sep;33(10):2891-903.
18. Hong YJ, etal., J Korean Med Sci. 2012 May;27(5):484-8. doi: 10.3346/jkms.2012.27.5.484. Epub 2012 Apr 25.
19. Kamino H, etal., J Cutan Pathol. 2009 Aug;36(8):845-52. doi: 10.1111/j.1600-0560.2008.01170.x. Epub 2008 Nov 19.
20. Kelleher CM, etal., Am J Respir Cell Mol Biol. 2005 Oct;33(4):355-62. Epub 2005 Aug 4.
21. Kondo N, etal., Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1101-5. doi: 10.1167/iovs.07-1145.
22. Kotzot D, etal., Eur J Pediatr. 1995 Jun;154(6):477-82.
23. Krex D, etal., Cerebrovasc Dis. 2004;18(2):104-10. Epub 2004 Jun 22.
24. Lemack GE, etal., Neurourol Urodyn 1999;18(1):55-68.
25. Li DY, etal., J Clin Invest 1998 Nov 15;102(10):1783-7.
26. Lima LH, etal., Ophthalmic Genet. 2011 Jun;32(2):80-2. doi: 10.3109/13816810.2010.544362. Epub 2011 Mar 10.
27. Lin G, etal., Cytotherapy. 2010;12(1):88-95. doi: 10.3109/14653240903350265.
28. Liu P, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(8):1354-7.
29. Mariani TJ, etal., Am J Pathol. 1995 Oct;147(4):988-1000.
30. Metcalfe K, etal., Eur J Hum Genet. 2000 Dec;8(12):955-63.
31. MGD and Homologene mouse data transfer
32. MGD data from the GO Consortium
33. Netland PA, etal., Ophthalmology. 1995 Jun;102(6):878-86.
34. Ng K, etal., Am J Physiol Renal Physiol. 2011 Jun;300(6):F1431-6. doi: 10.1152/ajprenal.00079.2011. Epub 2011 Apr 6.
35. Nicoloff G, etal., Gen Pharmacol. 2000 Aug;35(2):83-7.
36. Ogata T, etal., J Vasc Surg. 2005 Jun;41(6):1036-42.
37. Oikarinen AI, etal., J Am Acad Dermatol. 1984 Jul;11(1):64-72.
38. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
39. OMIM Disease Annotation Pipeline
40. Pellicoro A, etal., Hepatology. 2012 Jun;55(6):1965-75. doi: 10.1002/hep.25567. Epub 2012 Apr 18.
41. RGD automated import pipeline
42. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
43. RGD automated import pipeline for gene-chemical interactions
44. Rodriguez-Revenga L, etal., Arch Dermatol. 2004 Sep;140(9):1135-9.
45. Schroder A, etal., J Urol. 2013 Jun;189(6):2377-84. doi: 10.1016/j.juro.2012.12.110. Epub 2013 Jan 9.
46. Schwartz E, etal., Exp Mol Pathol. 1991 Oct;55(2):190-5.
47. Sephel GC, etal., J Invest Dermatol. 1989 Jul;93(1):147-53.
48. Sivaprasad S, etal., Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3046-51.
49. Szabo Z, etal., J Med Genet. 2006 Mar;43(3):255-8. Epub 2005 Aug 5.
50. Tanaka K, etal., Mol Vis. 2011;17:2751-8. Epub 2011 Oct 22.
51. Urban Z, etal., J Invest Dermatol. 2005 Jun;124(6):1193-9.
52. Valero MC, etal., Genomics 2000 Oct 1;69(1):1-13.
53. Wang IJ, etal., Am J Pathol. 2000 Oct;157(4):1269-76.
54. Xiong J, etal., J Vasc Surg. 2008 Oct;48(4):965-73. doi: 10.1016/j.jvs.2008.04.016. Epub 2008 Jun 30.
55. Zelickson AS, etal., J Am Acad Dermatol. 1980 Aug;3(2):186-92.
56. Zhang MC, etal., J Biol Chem. 1999 Jan 8;274(2):981-6.
Additional References at PubMed
PMID:1981051   PMID:2014796   PMID:7829060   PMID:8096378   PMID:9374392   PMID:9382709   PMID:9607766   PMID:10349636   PMID:10544250   PMID:10552047   PMID:10600892   PMID:10613847  
PMID:10675334   PMID:10848613   PMID:10861287   PMID:10970822   PMID:11042159   PMID:11076861   PMID:11082275   PMID:11217851   PMID:11431694   PMID:11514592   PMID:11779826   PMID:11970905  
PMID:12466207   PMID:12477932   PMID:12592609   PMID:12626514   PMID:12909585   PMID:12952863   PMID:14499643   PMID:14597767   PMID:14614988   PMID:15018818   PMID:15615710   PMID:15710889  
PMID:15863465   PMID:15900406   PMID:16141072   PMID:16141073   PMID:16192629   PMID:16236725   PMID:16251195   PMID:16602821   PMID:16783635   PMID:16830225   PMID:16982180   PMID:16989802  
PMID:17099216   PMID:17142349   PMID:17400710   PMID:17626896   PMID:17656671   PMID:18083765   PMID:18173368   PMID:18258849   PMID:18311803   PMID:18321928   PMID:18441095   PMID:18479957  
PMID:18487037   PMID:18495804   PMID:18506002   PMID:18554416   PMID:18591670   PMID:18614015   PMID:18635823   PMID:18651661   PMID:18667463   PMID:18757743   PMID:18772328   PMID:19185580  
PMID:19372465   PMID:19850904   PMID:19897741   PMID:19915155   PMID:20019329   PMID:20356956   PMID:20495146   PMID:20498044   PMID:20576933   PMID:20595636   PMID:20847053   PMID:20926892  
PMID:21267068   PMID:21281809   PMID:21305018   PMID:21438071   PMID:21490399   PMID:21513708   PMID:21536846   PMID:21707943   PMID:21730037   PMID:21778429   PMID:21856305   PMID:21873635  
PMID:21979435   PMID:21985298   PMID:22049077   PMID:22096492   PMID:22159717   PMID:22238283   PMID:22265892   PMID:22331032   PMID:22573328   PMID:22682244   PMID:22685574   PMID:22899851  
PMID:23011393   PMID:23261250   PMID:23273220   PMID:23322300   PMID:23493289   PMID:23696835   PMID:23723064   PMID:23817199   PMID:23857752   PMID:23895934   PMID:23938297   PMID:23994172  
PMID:24036114   PMID:24131868   PMID:24262428   PMID:24282586   PMID:24291458   PMID:24322348   PMID:24368172   PMID:24414067   PMID:24777781   PMID:24793170   PMID:24886827   PMID:25086405  
PMID:25131766   PMID:25166724   PMID:25395457   PMID:25428696   PMID:25539853   PMID:25652465   PMID:25670798   PMID:25701072   PMID:25771258   PMID:25923353   PMID:26027930   PMID:26167199  
PMID:26232234   PMID:26439735   PMID:26711913   PMID:26743624   PMID:26858344   PMID:26878215   PMID:26932671   PMID:26982166   PMID:27183603   PMID:27364009   PMID:27527664   PMID:27645581  
PMID:28071719   PMID:28237967   PMID:28254817   PMID:28684544   PMID:28751568   PMID:28754555   PMID:29251627   PMID:29366776   PMID:29498532   PMID:29665133   PMID:29802129   PMID:29956664  
PMID:30346946   PMID:30348760   PMID:30389913   PMID:30578393   PMID:30713523   PMID:31282949   PMID:31590613   PMID:31624071   PMID:31634485   PMID:31691186   PMID:31844321   PMID:32046118  
PMID:32151560   PMID:32412588   PMID:32460513   PMID:33035438   PMID:33153107  


Genomics

Comparative Map Data
Eln
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395134,731,449 - 134,776,300 (-)NCBIGRCm39mm39
GRCm39 Ensembl5134,731,447 - 134,776,177 (-)Ensembl
GRCm385134,702,595 - 134,747,368 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,702,593 - 134,747,323 (-)EnsemblGRCm38mm10GRCm38
MGSCv375135,178,466 - 135,223,124 (-)NCBIGRCm37mm9NCBIm37
MGSCv365134,987,223 - 135,031,881 (-)NCBImm8
Celera5131,710,617 - 131,755,279 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.76NCBI
ELN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl774,027,789 - 74,069,907 (+)EnsemblGRCh38hg38GRCh38
GRCh38774,027,772 - 74,069,907 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,442,503 - 73,484,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,080,363 - 73,122,173 (+)NCBINCBI36hg18NCBI36
Build 34772,887,168 - 72,927,681NCBI
Celera768,923,491 - 68,963,674 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,326,571 - 69,367,012 (+)NCBIHuRef
CHM1_1773,587,503 - 73,629,630 (+)NCBICHM1_1
CRA_TCAGchr7v2772,775,191 - 72,817,309 (+)NCBI
Eln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21221,968,544 - 22,011,929 (+)NCBI
Rnor_6.0 Ensembl1224,978,483 - 25,021,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01224,978,478 - 25,021,864 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,978,748 - 27,022,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,033,657 - 23,077,043 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11222,892,500 - 22,934,907 (+)NCBI
Celera1223,732,827 - 23,776,213 (+)NCBICelera
RH 3.4 Map12345.7RGD
RH 3.4 Map12344.2RGD
Cytogenetic Map12q12NCBI
Eln
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545613,788,992 - 13,818,836 (-)NCBIChiLan1.0ChiLan1.0
ELN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1781,177,699 - 81,218,306 (+)NCBIpanpan1.1PanPan1.1panPan2
ELN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,299,524 - 6,331,425 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,300,727 - 6,331,325 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,997,308 - 8,029,192 (-)NCBI
ROS_Cfam_1.066,114,552 - 6,146,504 (-)NCBI
UMICH_Zoey_3.166,104,697 - 6,136,585 (-)NCBI
UNSW_CanFamBas_1.066,052,537 - 6,084,439 (-)NCBI
UU_Cfam_GSD_1.066,216,223 - 6,248,126 (-)NCBI
Eln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344130,871,544 - 130,901,273 (-)NCBI
SpeTri2.0NW_0049365433,135,169 - 3,165,023 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl311,214,073 - 11,244,897 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1311,214,194 - 11,245,891 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,929,464 - 10,935,434 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,999,164 - 9,048,703 (-)NCBI
Eln
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474013,856,932 - 13,886,266 (-)NCBI

Position Markers
D5Mit282  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,746,693 - 134,746,794UniSTSGRCm38
MGSCv375135,222,563 - 135,222,664UniSTSGRCm37
Celera5131,754,718 - 131,754,819UniSTS
Cytogenetic Map5G2UniSTS
cM Map574.0UniSTS
Whitehead Genetic564.5UniSTS
Whitehead/MRC_RH51635.74UniSTS
Whitehead_YAC5 UniSTS
AI385707  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,702,945 - 134,703,068UniSTSGRCm38
MGSCv375135,178,815 - 135,178,938UniSTSGRCm37
Celera5131,710,966 - 131,711,089UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
Whitehead/MRC_RH51637.05UniSTS
Whitehead/MRC_RH51635.74UniSTS
G48109  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,738,648 - 134,738,776UniSTSGRCm38
MGSCv375135,214,518 - 135,214,646UniSTSGRCm37
Celera5131,746,673 - 131,746,801UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
G48111  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,726,444 - 134,726,664UniSTSGRCm38
MGSCv375135,202,314 - 135,202,534UniSTSGRCm37
Celera5131,734,465 - 131,734,685UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
G48112  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,706,238 - 134,706,373UniSTSGRCm38
MGSCv375135,182,108 - 135,182,243UniSTSGRCm37
Celera5131,714,259 - 131,714,394UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
G48151  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,728,439 - 134,728,580UniSTSGRCm38
MGSCv375135,204,309 - 135,204,450UniSTSGRCm37
Celera5131,736,460 - 131,736,601UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv375135,204,288 - 135,205,017UniSTSGRCm37
MGSCv375135,178,734 - 135,178,980UniSTSGRCm37
MGSCv375135,178,985 - 135,179,606UniSTSGRCm37
Celera5131,711,136 - 131,711,757UniSTS
Celera5131,736,439 - 131,737,168UniSTS
Celera5131,710,885 - 131,711,131UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
cM Map575.0UniSTS
D12Mgh12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,718,043 - 134,718,149UniSTSGRCm38
MGSCv375135,193,913 - 135,194,019UniSTSGRCm37
Celera5131,726,064 - 131,726,170UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,703,727 - 134,704,572UniSTSGRCm38
Celera5131,711,748 - 131,712,593UniSTS
Cytogenetic Map5G2UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,703,115 - 134,703,736UniSTSGRCm38
MGSCv375135,178,985 - 135,179,606UniSTSGRCm37
Celera5131,711,136 - 131,711,757UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,728,418 - 134,729,147UniSTSGRCm38
MGSCv375135,204,288 - 135,205,017UniSTSGRCm37
Celera5131,736,439 - 131,737,168UniSTS
Cytogenetic Map5G2UniSTS
cM Map575.0UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5G2UniSTS
Eln  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385134,702,864 - 134,703,110UniSTSGRCm38
MGSCv375135,178,734 - 135,178,980UniSTSGRCm37
Celera5131,710,885 - 131,711,131UniSTS
Cytogenetic Map5G2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119806972141714711Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121457140151834684Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121556974151834684Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124714580151834684Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125101165141714711Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125147702151834684Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129583274151834684Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129851021151834684Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5134002093151834684Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir497mmu-miR-497-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Western bloFunctional MTI21305018
Mir15ammu-miR-15a-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Western bloFunctional MTI21305018
Mir29ammu-miR-29a-3pMirecordsexternal_infoNANA18723672

Predicted Target Of
Summary Value
Count of predictions:169
Count of miRNA genes:147
Interacting mature miRNAs:165
Transcripts:ENSMUST00000015138
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000015138   ⟹   ENSMUSP00000015138
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5134,702,593 - 134,747,323 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201399
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5134,744,726 - 134,747,253 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201856   ⟹   ENSMUSP00000144555
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5134,702,838 - 134,747,246 (-)Ensembl
RefSeq Acc Id: ENSMUST00000202570
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5134,702,838 - 134,725,300 (-)Ensembl
RefSeq Acc Id: ENSMUST00000202620
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5134,725,603 - 134,729,106 (-)Ensembl
RefSeq Acc Id: NM_007925   ⟹   NP_031951
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395134,731,449 - 134,776,177 (-)NCBI
GRCm385134,702,595 - 134,747,323 (-)NCBI
MGSCv375135,178,466 - 135,223,124 (-)RGD
Celera5131,710,617 - 131,755,279 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011240855   ⟹   XP_011239157
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395134,731,692 - 134,776,300 (-)NCBI
GRCm385134,702,838 - 134,747,368 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_031951   ⟸   NM_007925
- Peptide Label: precursor
- UniProtKB: P54320 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011239157   ⟸   XM_011240855
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000015138   ⟸   ENSMUST00000015138
RefSeq Acc Id: ENSMUSP00000144555   ⟸   ENSMUST00000201856

Promoters
RGD ID:6888272
Promoter ID:EPDNEW_M7587
Type:initiation region
Name:Eln_1
Description:Mus musculus elastin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385134,747,254 - 134,747,314EPDNEW
RGD ID:6847905
Promoter ID:MM_ACW:39757
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ELN.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,205,116 - 135,205,616 (-)MPROMDB
RGD ID:6837411
Promoter ID:MM_KWN:44316
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_007925
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,222,571 - 135,223,071 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95317 AgrOrtholog
Ensembl Genes ENSMUSG00000029675 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000015138 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144555 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000015138 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000201856 UniProtKB/TrEMBL
InterPro Tropoelastin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13717 UniProtKB/Swiss-Prot
MGD MGI:95317 ENTREZGENE
NCBI Gene 13717 ENTREZGENE
PANTHER PTHR24018 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eln PhenoGen
UniProt A0A0J9YV95_MOUSE UniProtKB/TrEMBL
  ELN_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8C9L8 UniProtKB/Swiss-Prot