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Gene: Gpx1 (glutathione peroxidase 1) Mus musculus
Symbol: Gpx1
Name: glutathione peroxidase 1
Description: Exhibits glutathione peroxidase activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to oxidative stress; regulation of intracellular signal transduction; and skeletal muscle fiber development. Localizes to the mitochondrion. Predicted to colocalize with the Lewy body. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); pseudoxanthoma elasticum; and sickle cell anemia. Is expressed in several structures, including alimentary system; craniocervical region; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human GPX1 (glutathione peroxidase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI195024; AL033363; cellular glutathione peroxidase; CGPx; Gpx; GPx-1; GSHPx-1; selenium-dependent glutathione peroxidase 1
Homo sapiens (human) : GPX1 (glutathione peroxidase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gpx1 (glutathione peroxidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpx1 (glutathione peroxidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPX1 (glutathione peroxidase 1)
Canis lupus familiaris (dog) : GPX1 (glutathione peroxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpx1 (glutathione peroxidase 1)
Sus scrofa (pig) : GPX1 (glutathione peroxidase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389108,339,080 - 108,340,342 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,241,607 - 108,242,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,197,368 - 108,198,432 (+)NCBImm8
Celera9107,948,182 - 107,949,444 (+)NCBICelera
Cytogenetic Map9 F2NCBI
cM Map959.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gpx1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10681
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.