Gpx1 (glutathione peroxidase 1) - Rat Genome Database
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Gene: Gpx1 (glutathione peroxidase 1) Mus musculus
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Symbol: Gpx1
Name: glutathione peroxidase 1
RGD ID: 10681
Description: Exhibits glutathione peroxidase activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to oxidative stress; regulation of intracellular signal transduction; and skeletal muscle fiber development. Localizes to mitochondrion. Predicted to colocalize with Lewy body. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Orthologous to human GPX1 (glutathione peroxidase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI195024; AL033363; cellular glutathione peroxidase; CGP; CGPx; Gp; Gpx; GPx-; GPx-1; GSHPx; GSHPx-1; selenium-dependent glutathione peroxidase 1
Orthologs:
Homo sapiens (human) : GPX1 (glutathione peroxidase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gpx1 (glutathione peroxidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpx1 (glutathione peroxidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPX1 (glutathione peroxidase 1)
Canis lupus familiaris (dog) : GPX1 (glutathione peroxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpx1 (glutathione peroxidase 1)
Sus scrofa (pig) : GPX1 (glutathione peroxidase 1)
Chlorocebus sabaeus (African green monkey) : GPX1 (glutathione peroxidase 1)
Heterocephalus glaber (naked mole-rat) : Gpx1 (glutathione peroxidase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,216,279 - 108,217,541 (+)NCBI
GRCm389108,339,080 - 108,340,342 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,338,903 - 108,340,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,241,607 - 108,242,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,197,368 - 108,198,432 (+)NCBImm8
Celera9107,948,378 - 107,949,442 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
alpha thalassemia  (ISO)
anemia  (ISO)
Anorexia  (ISO)
arteriosclerosis  (IAGP)
autistic disorder  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2P  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
Cadmium Poisoning  (ISO)
calcinosis  (ISO)
Cardiovascular Abnormalities  (ISO)
cardiovascular system disease  (ISO)
carotid stenosis  (IMP)
cataract  (ISO)
Chronic Hepatitis  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (IEP,ISO)
dilated cardiomyopathy  (ISO)
epilepsy  (ISO)
Experimental Diabetes Mellitus  (ISO)
fatty liver disease  (ISO)
gestational diabetes  (ISO)
Glutathione Peroxidase Deficiency, Hemolytic Anemia possibly due to  (ISO)
hairy cell leukemia  (ISO)
Head and Neck Neoplasms  (ISO)
Hemolysis  (ISO)
Huntington's disease  (ISO)
hyperglycemia  (ISO)
hyperhomocysteinemia  (ISO)
hyperinsulinism  (ISO)
hypertension  (ISO)
hyperthyroidism  (ISO)
hypothyroidism  (ISO)
iron deficiency anemia  (ISO)
Iron Overload  (ISO)
Keshan disease  (ISO)
leukemia  (ISO)
Liver Injury  (ISO)
Lung Neoplasms  (ISO)
mental depression  (ISO)
Mercury Poisoning  (IEP)
multiple myeloma  (ISO)
myeloid neoplasm  (ISO)
myocardial infarction  (ISO)
nephrosis  (ISO)
non-alcoholic fatty liver disease  (IDA)
non-Hodgkin lymphoma  (ISO)
obesity  (ISO)
osteoporosis  (ISO)
Parkinson's disease  (ISO)
pseudoxanthoma elasticum  (ISO)
Reperfusion Injury  (ISO)
Reticulocytosis  (ISO)
senile cataract  (IMP)
sickle cell anemia  (IEP,ISO)
squamous cell carcinoma  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
vascular dementia  (ISO)
Venous Thrombosis  (IMP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-quinic acid  (ISO)
(R)-carnitine  (ISO)
(R)-lipoic acid  (ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (ISO)
11-deoxycorticosterone  (ISO)
12(S)-HPETE  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-tert-butylhydroquinone  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-nonylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acetic acid  (ISO)
acetylcholine  (EXP)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alpha,alpha-trehalose  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
AM-251  (ISO)
aminoglutethimide  (ISO)
aminoguanidine  (ISO)
amiodarone  (ISO)
amlexanox  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphibole asbestos  (ISO)
ampicillin  (ISO)
apigenin  (EXP)
apocynin  (EXP,ISO)
arachidonic acid  (ISO)
Aroclor 1254  (ISO)
arsenic acid  (EXP)
arsenic trichloride  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
atrasentan  (ISO)
atrazine  (EXP,ISO)
auranofin  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzopyran  (ISO)
berberine  (ISO)
beta-naphthoflavone  (ISO)
bifenthrin  (EXP)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bosentan  (ISO)
bromobenzene  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcium dichloride  (EXP)
camphene  (ISO)
capsaicin  (EXP)
carbon nanotube  (EXP)
carnosic acid  (ISO)
carnosine  (EXP)
celecoxib  (EXP)
chitosan  (ISO)
chloramine T  (ISO)
chloroform  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
chromium atom  (ISO)
chromium(6+)  (EXP,ISO)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
clofibrate  (ISO)
clozapine  (EXP)
cobalt atom  (EXP,ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
coumarin  (ISO)
crocetin  (EXP)
CU-O LINKAGE  (EXP)
cumene hydroperoxide  (EXP,ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP)
cypermethrin  (EXP)
cyprodinil  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP,ISO)
daunorubicin  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (EXP)
diclofenac  (ISO)
dieldrin  (EXP,ISO)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
diprotium oxide  (EXP)
diquat  (EXP)
disodium selenite  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ebselen  (EXP,ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (ISO)
emodin  (ISO)
endosulfan  (ISO)
enilconazole  (EXP)
enniatin  (EXP)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenamidone  (EXP)
fenofibrate  (EXP)
flavonoids  (ISO)
fludioxonil  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fructose  (ISO)
geneticin  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geraniol  (ISO)
ginsenoside Re  (EXP)
glafenine  (ISO)
glucose  (EXP,ISO)
glutathione  (EXP)
glyphosate  (ISO)
GW 4064  (EXP)
haloperidol  (EXP)
hexadecanoic acid  (ISO)
homocysteine  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (EXP,ISO)
hypochlorous acid  (EXP)
ifosfamide  (ISO)
iloprost  (EXP)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (EXP)
indometacin  (ISO)
iron atom  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
jaspamide  (ISO)
kainic acid  (EXP)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leptomycin B  (ISO)
limonene  (ISO)
linoleic acid hydroperoxide  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lovastatin  (EXP)
lutein  (EXP)
luteolin  (EXP)
Magnolol  (ISO)
mancozeb  (EXP)
maneb  (EXP,ISO)
manganese(II) chloride  (EXP)
melatonin  (EXP,ISO)
menadione  (ISO)
mephedrone  (EXP,ISO)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylglyoxal  (ISO)
methylmercury chloride  (EXP,ISO)
methylmercury(1+)  (EXP)
metronidazole  (ISO)
microcystin  (ISO)
microcystin-LR  (EXP)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (EXP)
monoethyl phthalate  (EXP)
monosodium L-glutamate  (EXP)
motexafin gadolinium  (ISO)
myricitrin  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-1,4-benzoquinone imine  (EXP)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (EXP)
naringin  (EXP)
nefazodone  (ISO)
neomycin  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (EXP)
nitroglycerin  (EXP)
Nodularin  (ISO)
NONOate(1-)  (EXP)
Nonylphenol  (EXP)
NS-398  (ISO)
NSC 23766  (EXP)
Nutlin-3  (ISO)
obeticholic acid  (EXP)
ochratoxin A  (ISO)
octadecanoic acid  (EXP)
oleanolic acid  (EXP)
omeprazole  (ISO)
organoselenium compound  (EXP)
orlistat  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (ISO)
peptidoglycan  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
peroxynitrous acid  (EXP)
phencyclidine  (EXP)
phenobarbital  (ISO)
phenylpropanolamine  (ISO)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphamidon  (EXP)
pirfenidone  (EXP)
pirinixic acid  (ISO)
porphyrins  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
probucol  (EXP,ISO)
propanal  (ISO)
prostaglandin E2  (EXP)
prostaglandin F2alpha  (EXP)
pterostilbene  (ISO)
Pyridostigmine bromide  (ISO)
pyrimethanil  (ISO)
quercetin  (EXP,ISO)
raspberry ketone  (EXP)
reactive oxygen species  (EXP,ISO)
resolvin D1  (EXP)
resveratrol  (EXP,ISO)
rosmarinic acid  (ISO)
rotenone  (EXP,ISO)
rutin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (EXP)
SB 203580  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenic acid  (EXP,ISO)
selenium atom  (EXP,ISO)
selenomethionine  (EXP,ISO)
silicic acid  (EXP)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silver(1+) nitrate  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (EXP)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
T-2 toxin  (EXP,ISO)
tamibarotene  (ISO)
tert-butyl ethyl ether  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thalidomide  (ISO)
theophylline  (ISO)
thiacloprid  (ISO)
thioacetamide  (EXP,ISO)
thiomalic acid  (ISO)
thymoquinone  (ISO)
thyroxine  (ISO)
titanium atom  (EXP)
titanium dioxide  (ISO)
tributyl phosphate  (ISO)
Tributyltin oxide  (ISO)
triclosan  (ISO)
trilobatin  (ISO)
triolein  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (EXP,ISO)
tris(2-butoxyethyl) phosphate  (EXP,ISO)
tris(2-chloroethyl) phosphate  (EXP)
troglitazone  (ISO)
uranium atom  (ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
water  (EXP)
zerumbone  (EXP)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc sulfate  (EXP)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis involved in wound healing  (IMP)
apoptotic process  (IMP)
arachidonic acid metabolic process  (IMP,ISO)
biological process involved in interaction with symbiont  (IGI)
blood vessel endothelial cell migration  (IMP)
cell population proliferation  (IMP)
cell redox homeostasis  (ISO)
cellular oxidant detoxification  (IBA)
cellular response to glucose stimulus  (ISO)
endothelial cell development  (IMP)
fat cell differentiation  (IMP)
glutathione metabolic process  (IBA,ISO)
heart contraction  (IMP,ISO)
hydrogen peroxide catabolic process  (IBA,IMP,ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (IMP)
lipid metabolic process  (IMP)
lipoxygenase pathway  (ISO)
myoblast proliferation  (IMP)
myotube differentiation  (IMP)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
negative regulation of inflammatory response to antigenic stimulus  (IGI)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (IMP)
negative regulation of release of cytochrome c from mitochondria  (ISO)
neuron apoptotic process  (IMP)
oxidation-reduction process  (IBA)
positive regulation of protein kinase B signaling  (IMP)
protein oxidation  (IMP)
regulation of gene expression, epigenetic  (ISO)
regulation of mammary gland epithelial cell proliferation  (ISO)
regulation of proteasomal protein catabolic process  (ISO)
response to estradiol  (ISO)
response to folic acid  (ISO)
response to gamma radiation  (IGI)
response to glucose  (ISO)
response to hormone  (ISO)
response to hydrogen peroxide  (IBA,IMP,ISO)
response to hydroperoxide  (IMP)
response to nicotine  (ISO)
response to organic cyclic compound  (ISO)
response to oxidative stress  (IGI,IMP)
response to reactive oxygen species  (IMP)
response to selenium ion  (IBA,ISO)
response to symbiotic bacterium  (IGI)
response to toxic substance  (IMP)
response to wounding  (IMP)
response to xenobiotic stimulus  (IMP)
sensory perception of sound  (IMP)
skeletal muscle fiber development  (IMP)
skeletal muscle tissue regeneration  (IMP)
temperature homeostasis  (IGI)
triglyceride metabolic process  (IMP)
UV protection  (ISO)
vasodilation  (IMP)

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO)
Lewy body  (ISO)
mitochondrion  (HDA,IBA,IDA,IMP,ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylsalicylic acid pharmacodynamics pathway  (ISO)
amyotrophic lateral sclerosis pathway  (IEA)
antipyrine drug pathway  (ISO)
arachidonic acid metabolic pathway  (IEA,ISO)
celecoxib pharmacodynamics pathway  (ISO)
diclofenac pharmacodynamics pathway  (ISO)
diflunisal pharmacodynamics pathway  (ISO)
etodolac pharmacodynamics pathway  (ISO)
fenoprofen pharmacodynamics pathway  (ISO)
flurbiprofen pharmacodynamics pathway  (ISO)
glutathione metabolic pathway  (IEA,ISO)
glutathione synthase deficiency pathway  (ISO)
glutathionuria disease pathway  (ISO)
Huntington's disease pathway  (IEA)
ibuprofen pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
ketoprofen pharmacodynamics pathway  (ISO)
ketorolac pharmacodynamics pathway  (ISO)
leukotriene C4 synthase deficiency pathway  (ISO)
lornoxicam pharmacodynamics pathway  (ISO)
magnesium salicylate pharmacodynamics pathway  (ISO)
mefenamic acid pharmacodynamics pathway  (ISO)
meloxicam pharmacodynamics pathway  (ISO)
nabumetone pharmacodynamics pathway  (ISO)
naproxen pharmacodynamics pathway  (ISO)
paracetamol drug pathway  (ISO)
piroxicam pharmacodynamics pathway  (ISO)
salicylic acid pharmacodynamics pathway  (ISO)
sodium salicylate pharmacodynamics pathway  (ISO)
sulindac pharmacodynamics pathway  (ISO)
tenoxicam pharmacodynamics pathway  (ISO)
tiaprofenic acid pharmacodynamics pathway  (ISO)
tolmetin pharmacodynamics pathway  (ISO)
valdecoxib pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal catalase activity  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell morphology  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal epididymis morphology  (IEA)
abnormal ileum crypts of Lieberkuhn morphology  (IAGP)
abnormal jejunum crypts of Lieberkuhn morphology  (IAGP)
abnormal lipid level  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal platelet physiology  (IAGP)
abnormal response to injury  (IAGP)
abnormal testis morphology  (IEA)
brain ischemia  (IAGP)
cachexia  (IAGP)
cataract  (IAGP)
cellular necrosis  (IAGP)
cochlear ganglion degeneration  (IAGP)
cochlear inner hair cell degeneration  (IAGP)
cochlear outer hair cell degeneration  (IAGP)
colitis  (IAGP)
crypts of Lieberkuhn abscesses  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased cell proliferation  (IAGP)
decreased cellular sensitivity to gamma-irradiation  (IAGP)
decreased circulating insulin level  (IEA)
decreased glutathione peroxidase activity  (IAGP)
diarrhea  (IAGP)
enlarged epididymis  (IEA)
impaired coordination  (IAGP)
increased cellular sensitivity to hydrogen peroxide  (IAGP)
increased cellular sensitivity to oxidative stress  (IAGP)
increased cerebral infarction size  (IAGP)
increased dopamine level  (IAGP)
increased inflammatory response  (IAGP)
increased neuron apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased serotonin level  (IAGP)
increased susceptibility to ischemic brain injury  (IAGP)
increased susceptibility to noise-induced hearing loss  (IAGP)
intestinal edema  (IAGP)
intestinal inflammation  (IAGP)
oxidative stress  (IAGP)
perianal ulcer  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
small intestinal inflammation  (IAGP)
small testis  (IEA)
References

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Additional References at PubMed
PMID:1593944   PMID:3015592   PMID:7578676   PMID:7667255   PMID:7671812   PMID:8165054   PMID:8566787   PMID:8662233   PMID:8720919   PMID:8759521   PMID:8792216   PMID:9011320  
PMID:9126277   PMID:9164985   PMID:9195979   PMID:9214310   PMID:9344593   PMID:9370288   PMID:9386101   PMID:9508085   PMID:9603263   PMID:9712879   PMID:9737717   PMID:9786216  
PMID:9788901   PMID:9792801   PMID:9820794   PMID:9843785   PMID:10349636   PMID:10421798   PMID:10428770   PMID:10490281   PMID:10627575   PMID:10754271   PMID:10759548   PMID:10915565  
PMID:10915653   PMID:10922068   PMID:10961904   PMID:11042159   PMID:11043909   PMID:11076861   PMID:11259653   PMID:11311045   PMID:11518697   PMID:11545230   PMID:11562367   PMID:11579147  
PMID:11672444   PMID:11726630   PMID:11823528   PMID:11893559   PMID:11898410   PMID:12117267   PMID:12196344   PMID:12368211   PMID:12429206   PMID:12466851   PMID:12477932   PMID:12482825  
PMID:12492400   PMID:12521604   PMID:12531513   PMID:12646716   PMID:12654481   PMID:12751789   PMID:12804009   PMID:12904583   PMID:14610273   PMID:14651853   PMID:14681479   PMID:14732290  
PMID:14871826   PMID:15182862   PMID:15242553   PMID:15663476   PMID:15698635   PMID:15782199   PMID:15789223   PMID:15795427   PMID:15824117   PMID:15827346   PMID:15831471   PMID:15920153  
PMID:15983212   PMID:16005359   PMID:16041008   PMID:16141072   PMID:16141073   PMID:16177185   PMID:16274876   PMID:16373599   PMID:16445905   PMID:16463122   PMID:16508038   PMID:16627788  
PMID:16636302   PMID:16721761   PMID:16723478   PMID:16783635   PMID:16831125   PMID:16916647   PMID:16934683   PMID:16962942   PMID:16998864   PMID:17047045   PMID:17138759   PMID:17145560  
PMID:17255533   PMID:17488888   PMID:17503775   PMID:17510403   PMID:17640558   PMID:18299484   PMID:18326824   PMID:18445702   PMID:18560803   PMID:18602426   PMID:18614015   PMID:18638544  
PMID:18691391   PMID:18727007   PMID:18760274   PMID:18762024   PMID:18776938   PMID:18799693   PMID:19074896   PMID:19141089   PMID:19170177   PMID:19352401   PMID:19423573   PMID:19466610  
PMID:19655411   PMID:19801492   PMID:19808019   PMID:19885949   PMID:19917877   PMID:19944066   PMID:19969073   PMID:20015939   PMID:20219985   PMID:20306076   PMID:20367278   PMID:20404090  
PMID:20511341   PMID:20578960   PMID:20586612   PMID:20627125   PMID:20823099   PMID:20828612   PMID:20848490   PMID:20872835   PMID:21145306   PMID:21166922   PMID:21193029   PMID:21323725  
PMID:21347610   PMID:21420488   PMID:21677750   PMID:21782974   PMID:21858002   PMID:21873635   PMID:22067043   PMID:22326323   PMID:22343415   PMID:22412999   PMID:22496890   PMID:22820179  
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PMID:26569096   PMID:26816051   PMID:26850477   PMID:26930476   PMID:27010651   PMID:27124582   PMID:27286733   PMID:27363720   PMID:27626380   PMID:27689697   PMID:27796745   PMID:27998725  
PMID:28039148   PMID:28069738   PMID:28070146   PMID:28385808   PMID:28597397   PMID:29502249   PMID:29908255   PMID:30592974   PMID:30685319   PMID:30938680   PMID:31059705   PMID:32152094  
PMID:32325033  


Genomics

Comparative Map Data
Gpx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,216,279 - 108,217,541 (+)NCBI
GRCm389108,339,080 - 108,340,342 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,338,903 - 108,340,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,241,607 - 108,242,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,197,368 - 108,198,432 (+)NCBImm8
Celera9107,948,378 - 107,949,442 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.24NCBI
GPX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,357,176 - 49,358,358 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,357,176 - 49,358,353 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,394,609 - 49,395,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,369,613 - 49,370,795 (-)NCBINCBI36hg18NCBI36
Build 34349,369,614 - 49,370,795NCBI
Celera349,359,484 - 49,360,663 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,454,091 - 49,455,270 (-)NCBIHuRef
CHM1_1349,347,422 - 49,348,601 (-)NCBICHM1_1
Gpx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,117,430 - 117,118,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,117,430 - 117,118,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,466,118 - 116,467,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,329,847 - 108,330,945 (+)ENTREZGENECelera
Cytogenetic Map8q32NCBI
Gpx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555321,298,336 - 1,298,830 (-)NCBIChiLan1.0ChiLan1.0
GPX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,360,736 - 50,362,274 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,360,947 - 50,361,826 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,280,038 - 49,281,455 (-)NCBIMhudiblu_PPA_v0panPan3
GPX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,889,174 - 39,890,260 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,889,165 - 39,890,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gpx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936529997,943 - 999,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,914,932 - 31,917,335 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,916,269 - 31,917,337 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,147,277 - 35,148,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPX1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,754,976 - 10,756,617 (-)NCBI
Gpx1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,313,773 - 3,314,870 (-)NCBI

Position Markers
AI195024  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,339,889 - 108,339,976UniSTSGRCm38
MGSCv379108,242,220 - 108,242,307UniSTSGRCm37
Celera9107,948,991 - 107,949,078UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
Whitehead/MRC_RH91112.23UniSTS
RH124241  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,340,087 - 108,340,202UniSTSGRCm38
MGSCv379108,242,418 - 108,242,533UniSTSGRCm37
Celera9107,949,189 - 107,949,304UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
PMC164851P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,339,425 - 108,339,921UniSTSGRCm38
MGSCv379108,241,756 - 108,242,252UniSTSGRCm37
Celera9107,948,527 - 107,949,023UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
Rhoa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,337,459 - 108,337,875UniSTSGRCm38
GRCm38264,866,865 - 64,867,364UniSTSGRCm38
Celera9107,946,561 - 107,946,977UniSTS
Celera266,537,733 - 66,538,236UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map9F1UniSTS
PMC200187P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,339,468 - 108,340,116UniSTSGRCm38
MGSCv379108,241,799 - 108,242,447UniSTSGRCm37
Celera9107,948,570 - 107,949,218UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
Gpx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,340,089 - 108,340,304UniSTSGRCm38
MGSCv379108,242,420 - 108,242,635UniSTSGRCm37
Celera9107,949,191 - 107,949,406UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
Gpx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,339,809 - 108,340,005UniSTSGRCm38
MGSCv379108,242,140 - 108,242,336UniSTSGRCm37
Celera9107,948,911 - 107,949,107UniSTS
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS
Gpx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F1UniSTS
cM Map957.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:128
Interacting mature miRNAs:138
Transcripts:ENSMUST00000082429
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001329527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW611014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY113381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK628430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000082429   ⟹   ENSMUSP00000081010
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,339,054 - 108,340,343 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191997   ⟹   ENSMUSP00000142257
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,339,243 - 108,340,250 (+)Ensembl
RefSeq Acc Id: ENSMUST00000192401
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,338,903 - 108,339,802 (+)Ensembl
RefSeq Acc Id: ENSMUST00000193987   ⟹   ENSMUSP00000141279
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,339,276 - 108,340,250 (+)Ensembl
RefSeq Acc Id: NM_001329527   ⟹   NP_001316456
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,216,279 - 108,217,541 (+)NCBI
GRCm389108,339,080 - 108,340,342 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001329528   ⟹   NP_001316457
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,216,279 - 108,217,541 (+)NCBI
GRCm389108,339,080 - 108,340,342 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008160   ⟹   NP_032186
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,216,279 - 108,217,541 (+)NCBI
GRCm389108,339,080 - 108,340,342 (+)ENTREZGENE
MGSCv379108,241,607 - 108,242,671 (+)RGD
Celera9107,948,182 - 107,949,444 (+)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032186   ⟸   NM_008160
- Peptide Label: isoform 1
- UniProtKB: P11352 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001316456   ⟸   NM_001329527
- Peptide Label: isoform 2
- UniProtKB: P11352 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001316457   ⟸   NM_001329528
- Peptide Label: isoform 3
- UniProtKB: P11352 (UniProtKB/Swiss-Prot),   A0A0A6YVV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000142257   ⟸   ENSMUST00000191997
RefSeq Acc Id: ENSMUSP00000141279   ⟸   ENSMUST00000193987
RefSeq Acc Id: ENSMUSP00000081010   ⟸   ENSMUST00000082429

Promoters
RGD ID:6844625
Promoter ID:MM_KWN:58786
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000082429
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369108,240,771 - 108,242,067 (+)MPROMDB
RGD ID:6849938
Promoter ID:EP11120
Type:single initiation site
Name:MM_GSHC
Description:Gluthathione peroxidase, GPX1 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:ubiquitous
Experiment Methods:Nuclease protection; Primer extension
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv379108,241,609 - 108,241,669EPD
MGSCv369108,241,609 - 108,241,669EPD
RGD ID:8670882
Promoter ID:EPDNEW_M13472
Type:initiation region
Name:Gpx1_1
Description:Mus musculus glutathione peroxidase 1 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389108,339,276 - 108,339,336EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104887 AgrOrtholog
Ensembl Genes ENSMUSG00000063856 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000081010 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141279 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000142257 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000082429 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000191997 UniProtKB/TrEMBL
  ENSMUST00000193987 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glutathione_peroxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPX_AS UniProtKB/Swiss-Prot
  GPX_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14775 UniProtKB/Swiss-Prot
MGD MGI:104887 ENTREZGENE
NCBI Gene 14775 ENTREZGENE
PANTHER PTHR11592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GSHPx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GPX1 RGD
PhenoGen Gpx1 PhenoGen
PIRSF Glutathion_perox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLUTPROXDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLUTATHIONE_PEROXID_1 UniProtKB/Swiss-Prot
  GLUTATHIONE_PEROXID_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.1090 ENTREZGENE
UniProt A0A0A6YVV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A0A6YY34_MOUSE UniProtKB/TrEMBL
  GPX1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P12079 UniProtKB/Swiss-Prot
  Q544W3 UniProtKB/Swiss-Prot
  Q5RJH8 UniProtKB/Swiss-Prot
  Q9CR54 UniProtKB/Swiss-Prot