Ltbp1 (latent transforming growth factor beta binding protein 1) - Rat Genome Database

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Gene: Ltbp1 (latent transforming growth factor beta binding protein 1) Mus musculus
Analyze
Symbol: Ltbp1
Name: latent transforming growth factor beta binding protein 1
RGD ID: 68548
MGI Page MGI
Description: Predicted to enable microfibril binding activity and transforming growth factor beta binding activity. Acts upstream of or within aorta development; coronary vasculature development; and ventricular septum development. Located in microfibril. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart; integumental system; and neural ectoderm. Orthologous to human LTBP1 (latent transforming growth factor beta binding protein 1); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430031G15Rik; 9830146M04; b2b1000C; b2b1000Clo; latent TGF beta binding protein; latent transforming growth factor beta binding protein 1L; latent-transforming growth factor beta-binding protein 1; Ltb; LTBP; Ltbp-1; Ltbp1L; TGF-beta1-BP-1; Tgfb; transforming growth factor beta-1-binding protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391775,312,475 - 75,699,507 (+)NCBIGRCm39mm39
GRCm39 Ensembl1775,312,563 - 75,699,507 (+)Ensembl
GRCm381775,005,480 - 75,392,512 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1775,005,568 - 75,392,512 (+)EnsemblGRCm38mm10GRCm38
MGSCv371775,404,869 - 75,791,109 (+)NCBIGRCm37mm9NCBIm37
MGSCv361774,910,589 - 75,296,829 (+)NCBImm8
Celera1779,300,183 - 79,689,321 (+)NCBICelera
Cytogenetic Map17E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
apigenin  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bucladesine  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
flavonoids  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (ISO)
glyphosate  (ISO)
graphite  (ISO)
GW 4064  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
L-methionine  (EXP)
Licochalcone B  (ISO)
medroxyprogesterone acetate  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (EXP)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
p-toluidine  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
SB 431542  (EXP,ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal ascending aorta and coronary artery attachment  (IAGP)
abnormal cardiac neural crest cell morphology  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal incisor morphology  (IEA)
abnormal jaw morphology  (IAGP)
abnormal lower incisor morphology  (IAGP)
abnormal radius morphology  (IEA)
abnormal snout morphology  (IEA)
abnormal tooth morphology  (IEA)
abnormal truncus arteriosus septation  (IAGP)
abnormal ulna morphology  (IEA)
abnormal vascular smooth muscle morphology  (IAGP)
common atrium  (IAGP)
cyanosis  (IAGP)
decreased body length  (IEA)
decreased body weight  (IEA)
decreased bone mineral content  (IEA)
decreased circulating alanine transaminase level  (IEA)
decreased circulating aspartate transaminase level  (IEA)
decreased circulating cholesterol level  (IEA)
decreased circulating HDL cholesterol level  (IEA)
decreased circulating iron level  (IEA)
decreased circulating LDL cholesterol level  (IEA)
decreased circulating serum albumin level  (IEA)
decreased circulating total protein level  (IEA)
decreased total body fat amount  (IEA)
dilated renal tubules  (IEA)
double outlet right ventricle  (IEA)
increased blood urea nitrogen level  (IEA)
increased hemoglobin content  (IEA)
increased leukocyte cell number  (IEA)
increased mean corpuscular hemoglobin  (IEA)
interrupted aortic arch  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
liver fibrosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
persistent truncus arteriosis  (IAGP)
polycystic kidney  (IEA)
renal glomerulus cysts  (IEA)
right aortic arch  (IAGP)
short mandible  (IAGP)
short maxilla  (IAGP)
short snout  (IAGP)
small basioccipital bone  (IAGP)
small basisphenoid bone  (IAGP)
vascular ring  (IEA)
References

Additional References at PubMed
PMID:7730318   PMID:9008713   PMID:9931372   PMID:10349636   PMID:10725249   PMID:10743502   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11104663   PMID:12142025   PMID:12477932  
PMID:12711388   PMID:12711389   PMID:12962157   PMID:14610273   PMID:14975714   PMID:15225218   PMID:15611103   PMID:15677465   PMID:15870109   PMID:16141072   PMID:16141073   PMID:16260650  
PMID:16602821   PMID:17015622   PMID:17804598   PMID:17950478   PMID:18287559   PMID:18508077   PMID:18516051   PMID:18672106   PMID:18812170   PMID:19022904   PMID:19334288   PMID:19349279  
PMID:19449303   PMID:19501082   PMID:20436479   PMID:20565961   PMID:21181942   PMID:21267068   PMID:21422469   PMID:21491542   PMID:21518438   PMID:21677750   PMID:21873635   PMID:22036565  
PMID:22045186   PMID:22159717   PMID:22560297   PMID:23183523   PMID:23462118   PMID:23479606   PMID:23645881   PMID:23804438   PMID:24006456   PMID:24262428   PMID:25762570   PMID:25805620  
PMID:25807483   PMID:26238476   PMID:26370502   PMID:26930384   PMID:27224923   PMID:27956181   PMID:28071719   PMID:28185240   PMID:28190767   PMID:29459677   PMID:30550785   PMID:31162944  
PMID:31343988   PMID:32325033  


Genomics

Comparative Map Data
Ltbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391775,312,475 - 75,699,507 (+)NCBIGRCm39mm39
GRCm39 Ensembl1775,312,563 - 75,699,507 (+)Ensembl
GRCm381775,005,480 - 75,392,512 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1775,005,568 - 75,392,512 (+)EnsemblGRCm38mm10GRCm38
MGSCv371775,404,869 - 75,791,109 (+)NCBIGRCm37mm9NCBIm37
MGSCv361774,910,589 - 75,296,829 (+)NCBImm8
Celera1779,300,183 - 79,689,321 (+)NCBICelera
Cytogenetic Map17E2NCBI
LTBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl232,946,953 - 33,399,509 (+)EnsemblGRCh38hg38GRCh38
GRCh38232,902,129 - 33,399,509 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37233,172,020 - 33,624,576 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36233,025,896 - 33,478,080 (+)NCBINCBI36hg18NCBI36
Build 34233,084,042 - 33,536,224NCBI
Celera233,011,085 - 33,463,289 (+)NCBI
Cytogenetic Map2p22.3NCBI
HuRef232,905,956 - 33,358,305 (+)NCBIHuRef
CHM1_1233,101,861 - 33,553,940 (+)NCBICHM1_1
Ltbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2620,029,629 - 20,425,339 (-)NCBI
Rnor_6.0 Ensembl621,203,502 - 21,600,451 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0621,203,502 - 21,600,441 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0631,097,090 - 31,491,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4619,942,626 - 20,355,084 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1620,157,811 - 20,358,038 (-)NCBI
Celera619,596,894 - 19,988,483 (-)NCBICelera
Cytogenetic Map6q13NCBI
Ltbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554411,232,041 - 1,627,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554411,405,340 - 1,626,668 (+)NCBIChiLan1.0ChiLan1.0
LTBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A33,854,604 - 34,120,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A33,667,191 - 34,120,602 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A32,956,937 - 33,409,286 (+)NCBIMhudiblu_PPA_v0panPan3
LTBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11726,129,528 - 26,521,782 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1726,130,781 - 26,521,779 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1725,920,743 - 26,311,820 (+)NCBI
ROS_Cfam_1.01726,696,150 - 27,088,547 (+)NCBI
UMICH_Zoey_3.11725,992,669 - 26,384,315 (+)NCBI
UNSW_CanFamBas_1.01726,065,391 - 26,457,908 (+)NCBI
UU_Cfam_GSD_1.01726,223,816 - 26,614,580 (+)NCBI
Ltbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629270,199,425 - 70,586,169 (+)NCBI
SpeTri2.0NW_004936493253,390 - 640,140 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3106,300,750 - 106,724,934 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13106,300,748 - 106,724,538 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23113,356,459 - 113,442,576 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LTBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11474,063,258 - 74,441,042 (-)NCBI
ChlSab1.1 Ensembl1474,064,087 - 74,548,825 (-)Ensembl
Vero_WHO_p1.0NW_02366604537,507,594 - 37,952,425 (+)NCBI
Ltbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473814,602,790 - 15,035,610 (+)NCBI

Position Markers
D17Mit111  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,109,377 - 75,109,517UniSTSGRCm38
MGSCv371775,508,717 - 75,508,857UniSTSGRCm37
Celera1779,403,646 - 79,403,786UniSTS
Cytogenetic Map17E3UniSTS
cM Map1745.3UniSTS
Whitehead Genetic1740.4UniSTS
Whitehead_YAC17 UniSTS
D17Mit219  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,365,287 - 75,365,410UniSTSGRCm38
MGSCv371775,764,627 - 75,764,750UniSTSGRCm37
Celera1779,662,818 - 79,662,941UniSTS
Cytogenetic Map17E3UniSTS
cM Map1745.3UniSTS
Whitehead Genetic1740.4UniSTS
Whitehead_YAC17 UniSTS
39.MMHAP36FRE12.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,279,501 - 75,279,663UniSTSGRCm38
MGSCv371775,678,841 - 75,679,003UniSTSGRCm37
Celera1779,575,468 - 79,575,630UniSTS
Cytogenetic Map17E3UniSTS
Whitehead/MRC_RH17885.67UniSTS
RH124446  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,033,906 - 75,034,075UniSTSGRCm38
MGSCv371775,433,246 - 75,433,415UniSTSGRCm37
Celera1779,328,380 - 79,328,549UniSTS
Cytogenetic Map17E3UniSTS
UniSTS:237697  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,175,788 - 75,176,030UniSTSGRCm38
MGSCv371775,575,128 - 75,575,370UniSTSGRCm37
Celera1779,470,504 - 79,470,746UniSTS
Cytogenetic Map17E3UniSTS
UniSTS:224340  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381775,251,811 - 75,251,967UniSTSGRCm38
MGSCv371775,651,151 - 75,651,307UniSTSGRCm37
Celera1779,547,744 - 79,547,900UniSTS
Cytogenetic Map17E3UniSTS
Ltbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17E3UniSTS
cM Map1746.24UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174620000082100000Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined174989696283897108Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175145143085451617Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175145143085451617Mouse
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175680065690800808Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175680065690800808Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175680065690800808Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175680065690800808Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175680065690800808Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175680065690800808Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5722744780578347Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175722744793199751Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5728209491282202Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176199358194987271Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176199358194987271Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176357811994987271Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176490750994987271Mouse
14928308Manh82_mmandible shape 82 (mouse)176600781494987271Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176863389194987271Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177039377094987271Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177039377094987271Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177039377094987271Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177039377094987271Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177308770494987271Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177308770494987271Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7380065693199751Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177428209490087842Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177428209490087842Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:995
Count of miRNA genes:430
Interacting mature miRNAs:480
Transcripts:ENSMUST00000001927, ENSMUST00000112514, ENSMUST00000112516, ENSMUST00000127458, ENSMUST00000135447, ENSMUST00000135750, ENSMUST00000146839
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001331233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001331234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001331235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001331236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001331237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_206958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF280604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH012192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY143161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB548403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB613838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT033758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV559283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF635913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000001927   ⟹   ENSMUSP00000001927
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,005,568 - 75,391,767 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112514   ⟹   ENSMUSP00000108133
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,178,911 - 75,391,326 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112516   ⟹   ENSMUSP00000108135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,178,810 - 75,391,336 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127458
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,289,976 - 75,294,369 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135447   ⟹   ENSMUSP00000116890
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,178,810 - 75,348,933 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135750
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,384,210 - 75,392,512 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146839
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,006,294 - 75,008,799 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234008
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,005,818 - 75,047,786 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234327   ⟹   ENSMUSP00000157367
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,310,156 - 75,315,125 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234490   ⟹   ENSMUSP00000157016
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1775,005,568 - 75,391,328 (+)Ensembl
RefSeq Acc Id: NM_001331233   ⟹   NP_001318162
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001331234   ⟹   NP_001318163
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001331235   ⟹   NP_001318164
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001331236   ⟹   NP_001318165
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001331237   ⟹   NP_001318166
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_019919   ⟹   NP_064303
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,524 - 75,699,507 (+)NCBI
GRCm381775,005,529 - 75,392,512 (+)NCBI
MGSCv371775,404,869 - 75,791,109 (+)RGD
Celera1779,300,183 - 79,690,519 (+)ENTREZGENE
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_206958   ⟹   NP_996841
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,776 - 75,699,507 (+)NCBI
GRCm381775,178,781 - 75,392,512 (+)NCBI
MGSCv371775,404,869 - 75,791,109 (+)RGD
Celera1779,300,183 - 79,690,519 (+)ENTREZGENE
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006524348   ⟹   XP_006524411
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
GRCm381775,005,480 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524349   ⟹   XP_006524412
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,331 (+)NCBI
GRCm381775,005,480 - 75,391,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524350   ⟹   XP_006524413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
GRCm381775,005,480 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524351   ⟹   XP_006524414
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
GRCm381775,005,480 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524353   ⟹   XP_006524416
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,485,541 - 75,698,770 (+)NCBI
GRCm381775,178,546 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317493   ⟹   XP_017172982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
GRCm381775,005,480 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249831   ⟹   XP_030105691
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
GRCm381775,005,480 - 75,391,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036160631   ⟹   XP_036016524
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391775,312,475 - 75,698,770 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_064303   ⟸   NM_019919
- Peptide Label: isoform LTBP-1L precursor
- UniProtKB: Q8CG19 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_996841   ⟸   NM_206958
- Peptide Label: isoform LTBP-1S precursor
- UniProtKB: Q8CG19 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006524412   ⟸   XM_006524349
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006524411   ⟸   XM_006524348
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006524413   ⟸   XM_006524350
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006524414   ⟸   XM_006524351
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006524416   ⟸   XM_006524353
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017172982   ⟸   XM_017317493
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_030105691   ⟸   XM_030249831
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001318163   ⟸   NM_001331234
- Peptide Label: isoform 4 precursor
RefSeq Acc Id: NP_001318162   ⟸   NM_001331233
- Peptide Label: isoform 3 precursor
RefSeq Acc Id: NP_001318166   ⟸   NM_001331237
- Peptide Label: isoform 7 precursor
- UniProtKB: Q8CG19 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001318165   ⟸   NM_001331236
- Peptide Label: isoform 6 precursor
RefSeq Acc Id: NP_001318164   ⟸   NM_001331235
- Peptide Label: isoform 5 precursor
RefSeq Acc Id: ENSMUSP00000108135   ⟸   ENSMUST00000112516
RefSeq Acc Id: ENSMUSP00000108133   ⟸   ENSMUST00000112514
RefSeq Acc Id: ENSMUSP00000116890   ⟸   ENSMUST00000135447
RefSeq Acc Id: ENSMUSP00000001927   ⟸   ENSMUST00000001927
RefSeq Acc Id: ENSMUSP00000157016   ⟸   ENSMUST00000234490
RefSeq Acc Id: ENSMUSP00000157367   ⟸   ENSMUST00000234327
RefSeq Acc Id: XP_036016524   ⟸   XM_036160631
- Peptide Label: isoform X5
Protein Domains
EGF-like   TB

Promoters
RGD ID:13676780
Promoter ID:EPDNEW_M22539
Type:multiple initiation site
Name:Ltbp1_1
Description:Mus musculus latent transforming growth factor beta binding protein1 , transcript variant 7, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22540  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381775,005,554 - 75,005,614EPDNEW
RGD ID:13676782
Promoter ID:EPDNEW_M22540
Type:single initiation site
Name:Ltbp1_2
Description:Mus musculus latent transforming growth factor beta binding protein1 , transcript variant 7, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22539  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381775,178,955 - 75,179,015EPDNEW
RGD ID:6828314
Promoter ID:MM_KWN:24206
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000079577,   ENSMUST00000112518,   NM_019919,   OTTMUST00000047996
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361775,404,611 - 75,405,262 (+)MPROMDB
RGD ID:6828315
Promoter ID:MM_KWN:24208
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000112514,   ENSMUST00000112516,   OTTMUST00000047993
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361775,577,841 - 75,578,341 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109151 AgrOrtholog
Ensembl Genes ENSMUSG00000001870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000001927 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000108133 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000108135 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000116890 UniProtKB/TrEMBL
  ENSMUSP00000157016 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157367 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001927 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000112514 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000112516 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000135447 UniProtKB/TrEMBL
  ENSMUST00000234327 UniProtKB/TrEMBL
  ENSMUST00000234490 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.90.290.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:268977 UniProtKB/Swiss-Prot
MGD MGI:109151 ENTREZGENE
NCBI Gene 268977 ENTREZGENE
Pfam cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  PF00683 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ltbp1 PhenoGen
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS51364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57581 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3Q4EGK3_MOUSE UniProtKB/TrEMBL
  A0A3Q4L384_MOUSE UniProtKB/TrEMBL
  B1B1E2_MOUSE UniProtKB/TrEMBL
  LTBP1_MOUSE UniProtKB/Swiss-Prot
  Q8C6S0_MOUSE UniProtKB/TrEMBL
  Q8CG19 ENTREZGENE
  Q99PJ3_MOUSE UniProtKB/TrEMBL
UniProt Secondary B1B1D9 UniProtKB/Swiss-Prot
  B1B1E1 UniProtKB/Swiss-Prot
  O88349 UniProtKB/Swiss-Prot
  Q505C9 UniProtKB/Swiss-Prot
  Q8BNW7 UniProtKB/Swiss-Prot
  Q8C7F5 UniProtKB/Swiss-Prot
  Q8CG18 UniProtKB/Swiss-Prot
  Q8CIR0 UniProtKB/Swiss-Prot