Tacc3 (transforming, acidic coiled-coil containing protein 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tacc3 (transforming, acidic coiled-coil containing protein 3) Mus musculus
Analyze
Symbol: Tacc3
Name: transforming, acidic coiled-coil containing protein 3
RGD ID: 1550045
MGI Page MGI
Description: Enables protein domain specific binding activity. Acts upstream of or within several processes, including astral microtubule organization; cytoplasmic sequestering of transcription factor; and nervous system development. Located in centrosome and cytoplasm. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Orthologous to human TACC3 (transforming acidic coiled-coil containing protein 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A; Aint; Arnt interacting protein; ARNT-interacting protein; C86661; Eric1; transforming acidic coiled-coil-containing protein 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm19067   Gm2053  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,814,808 - 33,836,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,815,472 - 33,836,339 (+)EnsemblGRCm39 Ensembl
GRCm38533,658,128 - 33,672,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,658,128 - 33,678,995 (+)EnsemblGRCm38mm10GRCm38
MGSCv37534,000,796 - 34,014,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,975,519 - 33,989,055 (+)NCBIMGSCv36mm8
Celera531,134,263 - 31,148,314 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-hydroxynon-2-enal  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (EXP,ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
diallyl trisulfide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
diethyl malate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
folic acid  (EXP,ISO)
FR900359  (ISO)
gallic acid  (ISO)
genistein  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
lidocaine  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N-Nitrosopyrrolidine  (ISO)
niclosamide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms. Still IH, etal., BMC Evol Biol 2004 Jun 18;4(1):16.
Additional References at PubMed
PMID:10349636   PMID:10366448   PMID:10635326   PMID:10922068   PMID:11025203   PMID:11042159   PMID:11076861   PMID:11298601   PMID:11847113   PMID:11980711   PMID:12015314   PMID:12237944  
PMID:12389629   PMID:12477932   PMID:12642624   PMID:14610273   PMID:14681479   PMID:15037632   PMID:15226440   PMID:15234987   PMID:15237213   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:17060449   PMID:17359303   PMID:17920017   PMID:18287559   PMID:18799693   PMID:20059953   PMID:20360068   PMID:20804727   PMID:21267068   PMID:21685933   PMID:21862448   PMID:21873635  
PMID:22842144   PMID:22988430   PMID:23240775   PMID:23918938   PMID:24273164   PMID:27157623   PMID:28671696   PMID:33318147   PMID:33901174   PMID:34321999   PMID:38413710  


Genomics

Comparative Map Data
Tacc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,814,808 - 33,836,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,815,472 - 33,836,339 (+)EnsemblGRCm39 Ensembl
GRCm38533,658,128 - 33,672,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,658,128 - 33,678,995 (+)EnsemblGRCm38mm10GRCm38
MGSCv37534,000,796 - 34,014,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,975,519 - 33,989,055 (+)NCBIMGSCv36mm8
Celera531,134,263 - 31,148,314 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
TACC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,721,521 - 1,745,171 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,712,858 - 1,745,171 (+)EnsemblGRCh38hg38GRCh38
GRCh3741,723,248 - 1,746,898 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,693,062 - 1,716,696 (+)NCBINCBI36Build 36hg18NCBI36
Build 3441,690,496 - 1,714,126NCBI
Celera41,634,312 - 1,657,939 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,666,111 - 1,689,797 (+)NCBIHuRef
CHM1_141,721,189 - 1,744,883 (+)NCBICHM1_1
T2T-CHM13v2.041,719,323 - 1,742,998 (+)NCBIT2T-CHM13v2.0
Tacc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,275,755 - 81,289,894 (-)NCBIGRCr8
mRatBN7.21477,051,209 - 77,065,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,503,501 - 81,517,450 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,744,101 - 82,758,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,189,401 - 79,203,350 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,336,283 - 82,350,069 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,336,324 - 82,347,679 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,025,668 - 83,039,454 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,746,460 - 82,760,864 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11482,748,850 - 82,763,255 (-)NCBI
Celera1475,974,760 - 75,988,702 (-)NCBICelera
Cytogenetic Map14q21NCBI
Tacc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955514975,176 - 986,686 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955514973,457 - 986,640 (+)NCBIChiLan1.0ChiLan1.0
TACC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v232,049,942 - 2,074,164 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,985,172 - 2,009,451 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,858,595 - 1,882,727 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.141,772,836 - 1,796,019 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl41,772,836 - 1,796,019 (+)Ensemblpanpan1.1panPan2
TACC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1362,368,641 - 62,380,898 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl362,368,642 - 62,381,024 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha364,886,359 - 64,898,622 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0362,844,062 - 62,856,319 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl362,844,062 - 62,856,561 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1362,337,573 - 62,349,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0362,541,079 - 62,553,340 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0362,900,317 - 62,912,580 (-)NCBIUU_Cfam_GSD_1.0
Tacc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528567,947,880 - 67,964,536 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647721,648,716 - 21,665,625 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647721,648,958 - 21,665,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TACC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8824,999 - 837,322 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18825,433 - 835,425 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28296,955 - 306,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TACC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12747,021,970 - 47,045,571 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2747,021,965 - 47,045,223 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660513,398,606 - 3,422,223 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tacc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475525,683,137 - 25,692,504 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475525,683,314 - 25,695,102 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:795
Count of miRNA genes:382
Interacting mature miRNAs:414
Transcripts:ENSMUST00000074849, ENSMUST00000079534, ENSMUST00000114426, ENSMUST00000138240, ENSMUST00000139453, ENSMUST00000139888, ENSMUST00000152847
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse

Markers in Region
C86661  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38533,671,704 - 33,672,118UniSTSGRCm38
MGSCv37534,014,353 - 34,014,767UniSTSGRCm37
Celera531,147,820 - 31,148,234UniSTS
Cytogenetic Map5B2UniSTS
Whitehead/MRC_RH5444.52UniSTS
PMC125348P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38533,661,361 - 33,661,596UniSTSGRCm38
MGSCv37534,004,010 - 34,004,245UniSTSGRCm37
Celera531,137,477 - 31,137,712UniSTS
Cytogenetic Map5B2UniSTS
Tacc3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38533,661,253 - 33,661,591UniSTSGRCm38
MGSCv37534,003,902 - 34,004,240UniSTSGRCm37
Celera531,137,369 - 31,137,707UniSTS
Cytogenetic Map5B2UniSTS
cM Map5 UniSTS
Tacc3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5B2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001310541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_868281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF156934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF203445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF203446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF247674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB612450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000074849   ⟹   ENSMUSP00000074394
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,472 - 33,829,545 (+)Ensembl
GRCm38.p6 Ensembl533,658,128 - 33,672,201 (+)Ensembl
Ensembl Acc Id: ENSMUST00000079534   ⟹   ENSMUSP00000078491
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,472 - 33,836,339 (+)Ensembl
GRCm38.p6 Ensembl533,658,128 - 33,678,995 (+)Ensembl
Ensembl Acc Id: ENSMUST00000114426   ⟹   ENSMUSP00000110069
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,930 - 33,829,542 (+)Ensembl
GRCm38.p6 Ensembl533,658,586 - 33,672,198 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138240   ⟹   ENSMUSP00000115481
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,826,005 - 33,829,545 (+)Ensembl
GRCm38.p6 Ensembl533,668,661 - 33,672,201 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139453
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,978 - 33,819,359 (+)Ensembl
GRCm38.p6 Ensembl533,658,634 - 33,662,015 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139888   ⟹   ENSMUSP00000117407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,826,068 - 33,836,329 (+)Ensembl
GRCm38.p6 Ensembl533,668,724 - 33,678,985 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152847   ⟹   ENSMUSP00000119560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,898 - 33,821,627 (+)Ensembl
GRCm38.p6 Ensembl533,658,554 - 33,664,283 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201633   ⟹   ENSMUSP00000144567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl533,815,491 - 33,822,189 (+)Ensembl
GRCm38.p6 Ensembl533,658,147 - 33,664,845 (+)Ensembl
RefSeq Acc Id: NM_001040435   ⟹   NP_001035525
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
GRCm38533,658,128 - 33,672,202 (+)NCBI
MGSCv37534,000,796 - 34,014,847 (+)RGD
Celera531,134,263 - 31,148,314 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001310541   ⟹   NP_001297470
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
GRCm38533,658,128 - 33,672,202 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001405350   ⟹   NP_001392279
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405351   ⟹   NP_001392280
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,836,331 (+)NCBI
RefSeq Acc Id: NM_001405352   ⟹   NP_001392281
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405353   ⟹   NP_001392282
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405354   ⟹   NP_001392283
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405355   ⟹   NP_001392284
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405356   ⟹   NP_001392285
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,836,331 (+)NCBI
RefSeq Acc Id: NM_001405357   ⟹   NP_001392286
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405358   ⟹   NP_001392287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,829,542 (+)NCBI
RefSeq Acc Id: NM_001405360   ⟹   NP_001392289
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,929 - 33,836,331 (+)NCBI
RefSeq Acc Id: XM_006503832   ⟹   XP_006503895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,817,620 - 33,829,547 (+)NCBI
GRCm38533,660,274 - 33,672,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006503835   ⟹   XP_006503898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,955 - 33,829,547 (+)NCBI
GRCm38533,658,483 - 33,672,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011240715   ⟹   XP_011239017
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,817,499 - 33,829,547 (+)NCBI
GRCm38533,660,155 - 33,672,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011240716   ⟹   XP_011239018
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,989 - 33,829,542 (+)NCBI
GRCm38533,658,483 - 33,672,198 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254349   ⟹   XP_030110209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,939 - 33,829,547 (+)NCBI
GRCm38533,658,483 - 33,672,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254350   ⟹   XP_030110210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,814,808 - 33,829,544 (+)NCBI
GRCm38533,658,483 - 33,672,198 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254352   ⟹   XP_030110212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,928 - 33,829,542 (+)NCBI
GRCm38533,658,483 - 33,672,198 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036164983   ⟹   XP_036020876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,817,499 - 33,829,544 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003955613
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,817,499 - 33,829,544 (+)NCBI
GRCm38533,660,155 - 33,672,200 (+)NCBI
Sequence:
RefSeq Acc Id: XR_868281
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39533,815,989 - 33,829,542 (+)NCBI
GRCm38533,658,483 - 33,672,198 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001035525 (Get FASTA)   NCBI Sequence Viewer  
  NP_001297470 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392279 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392280 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392281 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392282 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392283 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392284 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392285 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392286 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392287 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392289 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503895 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503898 (Get FASTA)   NCBI Sequence Viewer  
  XP_011239017 (Get FASTA)   NCBI Sequence Viewer  
  XP_011239018 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110209 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110210 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110212 (Get FASTA)   NCBI Sequence Viewer  
  XP_036020876 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD25963 (Get FASTA)   NCBI Sequence Viewer  
  AAF85763 (Get FASTA)   NCBI Sequence Viewer  
  AAF97029 (Get FASTA)   NCBI Sequence Viewer  
  AAF97030 (Get FASTA)   NCBI Sequence Viewer  
  AAF98321 (Get FASTA)   NCBI Sequence Viewer  
  AAH03252 (Get FASTA)   NCBI Sequence Viewer  
  AAH66184 (Get FASTA)   NCBI Sequence Viewer  
  AAH68314 (Get FASTA)   NCBI Sequence Viewer  
  BAE26507 (Get FASTA)   NCBI Sequence Viewer  
  EDL37428 (Get FASTA)   NCBI Sequence Viewer  
  EDL37429 (Get FASTA)   NCBI Sequence Viewer  
  EDL37430 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000074394
  ENSMUSP00000074394.7
  ENSMUSP00000078491
  ENSMUSP00000078491.5
  ENSMUSP00000110069
  ENSMUSP00000110069.4
  ENSMUSP00000115481.3
  ENSMUSP00000117407.2
  ENSMUSP00000119560.2
  ENSMUSP00000144567.2
GenBank Protein Q9JJ11 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001035525   ⟸   NM_001040435
- Peptide Label: isoform 2
- UniProtKB: Q6NV52 (UniProtKB/TrEMBL),   Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503898   ⟸   XM_006503835
- Peptide Label: isoform X7
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503895   ⟸   XM_006503832
- Peptide Label: isoform X2
- UniProtKB: Q99LH8 (UniProtKB/TrEMBL),   Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239018   ⟸   XM_011240716
- Peptide Label: isoform X4
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239017   ⟸   XM_011240715
- Peptide Label: isoform X1
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297470   ⟸   NM_001310541
- Peptide Label: isoform 1
- UniProtKB: Q99LH8 (UniProtKB/TrEMBL),   Q9JIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030110209   ⟸   XM_030254349
- Peptide Label: isoform X3
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030110210   ⟸   XM_030254350
- Peptide Label: isoform X6
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030110212   ⟸   XM_030254352
- Peptide Label: isoform X9
Ensembl Acc Id: ENSMUSP00000117407   ⟸   ENSMUST00000139888
Ensembl Acc Id: ENSMUSP00000115481   ⟸   ENSMUST00000138240
Ensembl Acc Id: ENSMUSP00000078491   ⟸   ENSMUST00000079534
Ensembl Acc Id: ENSMUSP00000119560   ⟸   ENSMUST00000152847
Ensembl Acc Id: ENSMUSP00000074394   ⟸   ENSMUST00000074849
Ensembl Acc Id: ENSMUSP00000110069   ⟸   ENSMUST00000114426
Ensembl Acc Id: ENSMUSP00000144567   ⟸   ENSMUST00000201633
RefSeq Acc Id: XP_036020876   ⟸   XM_036164983
- Peptide Label: isoform X5
- UniProtKB: Q9JIQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001392285   ⟸   NM_001405356
- Peptide Label: isoform 2
- UniProtKB: Q6NV52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001392280   ⟸   NM_001405351
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001392289   ⟸   NM_001405360
- Peptide Label: isoform 9
RefSeq Acc Id: NP_001392286   ⟸   NM_001405357
- Peptide Label: isoform 2
- UniProtKB: Q6NV52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001392281   ⟸   NM_001405352
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001392287   ⟸   NM_001405358
- Peptide Label: isoform 9
RefSeq Acc Id: NP_001392279   ⟸   NM_001405350
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001392282   ⟸   NM_001405353
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001392284   ⟸   NM_001405355
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001392283   ⟸   NM_001405354
- Peptide Label: isoform 7
Protein Domains
Transforming acidic coiled-coil-containing protein

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JJ11-F1-model_v2 AlphaFold Q9JJ11 1-631 view protein structure

Promoters
RGD ID:6886432
Promoter ID:EPDNEW_M6667
Type:initiation region
Name:Tacc3_2
Description:Mus musculus transforming, acidic coiled-coil containing protein3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6668  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38533,658,103 - 33,658,163EPDNEW
RGD ID:6886434
Promoter ID:EPDNEW_M6668
Type:initiation region
Name:Tacc3_1
Description:Mus musculus transforming, acidic coiled-coil containing protein3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6667  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38533,658,585 - 33,658,645EPDNEW
RGD ID:6838515
Promoter ID:MM_KWN:41925
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000079534,   ENSMUST00000114422,   NM_001040435,   OTTMUST00000061652,   OTTMUST00000061677,   OTTMUST00000061678,   OTTMUST00000061696,   OTTMUST00000061698,   UC008XAZ.1,   UC008XBA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36534,000,406 - 34,001,287 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341163 AgrOrtholog
Ensembl Genes ENSMUSG00000037313 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074849 ENTREZGENE
  ENSMUST00000074849.13 UniProtKB/TrEMBL
  ENSMUST00000079534 ENTREZGENE
  ENSMUST00000079534.11 UniProtKB/TrEMBL
  ENSMUST00000114426 ENTREZGENE
  ENSMUST00000114426.10 UniProtKB/TrEMBL
  ENSMUST00000138240.5 UniProtKB/TrEMBL
  ENSMUST00000139888.5 UniProtKB/TrEMBL
  ENSMUST00000152847.8 UniProtKB/TrEMBL
  ENSMUST00000201633.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1700 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TACC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TACC_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21335 UniProtKB/TrEMBL
MGD MGI:1341163 ENTREZGENE
NCBI Gene 21335 ENTREZGENE
PANTHER PTHR13924 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TACC_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tacc3 PhenoGen
UniProt A0A0J9YVA2_MOUSE UniProtKB/TrEMBL
  D3Z1Y4_MOUSE UniProtKB/TrEMBL
  F6TNB3_MOUSE UniProtKB/TrEMBL
  F7AGT6_MOUSE UniProtKB/TrEMBL
  Q6NV52 ENTREZGENE, UniProtKB/TrEMBL
  Q99LH8 ENTREZGENE, UniProtKB/TrEMBL
  Q9ET42_MOUSE UniProtKB/TrEMBL
  Q9JIQ4_MOUSE UniProtKB/TrEMBL
  Q9JIQ5 ENTREZGENE, UniProtKB/TrEMBL
  Q9JJ11 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9WVK9 UniProtKB/Swiss-Prot