Orc1 (origin recognition complex, subunit 1) - Rat Genome Database

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Gene: Orc1 (origin recognition complex, subunit 1) Mus musculus
Analyze
Symbol: Orc1
Name: origin recognition complex, subunit 1
RGD ID: 1332182
MGI Page MGI
Description: Predicted to enable DNA replication origin binding activity and chromatin binding activity. Predicted to be involved in DNA replication initiation; positive regulation of smooth muscle cell proliferation; and regulation of cell cycle process. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in liver and submandibular gland. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Orthologous to human ORC1 (origin recognition complex subunit 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA545195; MmOR; MmORC1; Or; Orc1l; origin recognition complex subunit 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm19127  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394108,436,651 - 108,472,030 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4108,436,620 - 108,472,030 (+)EnsemblGRCm39 Ensembl
GRCm384108,575,705 - 108,616,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,579,423 - 108,614,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv374108,252,059 - 108,287,438 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364108,077,406 - 108,112,765 (+)NCBIMGSCv36mm8
Celera4106,922,805 - 106,959,019 (+)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-nitrophenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
azathioprine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clotrimazole  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
FR900359  (ISO)
furan  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
GW 3965  (ISO)
GW 4064  (ISO)
irinotecan  (ISO)
Lasiocarpine  (ISO)
lidocaine  (ISO)
MeIQx  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
niclosamide  (ISO)
nitrofen  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenacetin  (ISO)
phenylhydrazine  (ISO)
phytoestrogen  (ISO)
potassium dichromate  (EXP)
pravastatin  (EXP,ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trimellitic anhydride  (EXP)
Triptolide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals. Natale DA, etal., EMBO J 2000 Jun 1;19(11):2728-38.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Readout of epigenetic modifications. Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9862484   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:12614612   PMID:12904583   PMID:14610273   PMID:15489334  
PMID:15634681   PMID:16141072   PMID:16141073   PMID:18799693   PMID:20360068   PMID:21565611   PMID:21589869   PMID:21677750   PMID:21873635   PMID:22922362   PMID:24194600   PMID:24457600  
PMID:26584622   PMID:27626380   PMID:28700664   PMID:29967292   PMID:30973865   PMID:32325033   PMID:32808929   PMID:33230847   PMID:38009275  


Genomics

Comparative Map Data
Orc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394108,436,651 - 108,472,030 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4108,436,620 - 108,472,030 (+)EnsemblGRCm39 Ensembl
GRCm384108,575,705 - 108,616,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,579,423 - 108,614,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv374108,252,059 - 108,287,438 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364108,077,406 - 108,112,765 (+)NCBIMGSCv36mm8
Celera4106,922,805 - 106,959,019 (+)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.64NCBI
ORC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38152,372,829 - 52,409,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl152,372,829 - 52,404,423 (-)EnsemblGRCh38hg38GRCh38
GRCh37152,838,501 - 52,870,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36152,611,089 - 52,642,719 (-)NCBINCBI36Build 36hg18NCBI36
Build 34152,550,521 - 52,582,152NCBI
Celera151,125,195 - 51,156,841 (-)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef150,954,504 - 50,986,088 (-)NCBIHuRef
CHM1_1152,955,878 - 52,987,524 (-)NCBICHM1_1
T2T-CHM13v2.0152,254,294 - 52,290,972 (-)NCBIT2T-CHM13v2.0
Orc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,552,975 - 128,581,943 (+)NCBIGRCr8
mRatBN7.25123,324,273 - 123,348,375 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5123,324,315 - 123,348,375 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5125,951,118 - 125,970,825 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,674,202 - 127,693,909 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05127,725,496 - 127,745,203 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05128,186,651 - 128,212,901 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,190,708 - 128,210,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05132,027,128 - 132,053,582 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,881,973 - 129,901,675 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15129,887,198 - 129,906,901 (+)NCBI
Celera5122,062,985 - 122,082,678 (+)NCBICelera
Cytogenetic Map5q34NCBI
Orc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554646,764,992 - 6,787,066 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554646,761,046 - 6,787,144 (+)NCBIChiLan1.0ChiLan1.0
ORC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21174,445,007 - 174,481,020 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11173,587,081 - 173,622,999 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0151,630,344 - 51,666,327 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1153,238,377 - 53,273,653 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl153,238,377 - 53,273,653 (-)Ensemblpanpan1.1panPan2
ORC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1158,965,339 - 8,995,527 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl158,971,732 - 8,995,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,117,639 - 9,147,426 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0159,088,800 - 9,118,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl159,088,747 - 9,118,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1158,901,830 - 8,931,588 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0158,990,730 - 9,020,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0159,008,666 - 9,038,436 (+)NCBIUU_Cfam_GSD_1.0
Orc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505866,805,540 - 66,835,637 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365228,586,591 - 8,610,747 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365228,580,661 - 8,610,750 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6159,819,339 - 159,852,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16159,819,302 - 159,852,306 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26147,478,622 - 147,512,210 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ORC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12080,540,331 - 80,571,989 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2080,542,532 - 80,572,237 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603336,698,289 - 36,730,187 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Orc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624859833,793 - 863,539 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624859833,360 - 863,631 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Orc1
909 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:441
Count of miRNA genes:351
Interacting mature miRNAs:394
Transcripts:ENSMUST00000102744, ENSMUST00000129931, ENSMUST00000130162, ENSMUST00000139772, ENSMUST00000143497
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
10412193Plep_mplasma lepin levels (mouse)Not determined474444699108444983Mouse
11532700Sluc43d_msusceptibility to lung cancer 43d (mouse)474444699108444983Mouse
11532701Sluc43e_msusceptibility to lung cancer 43e (mouse)474444699108444983Mouse
11532702Sluc43f_msusceptibility to lung cancer 43f (mouse)474444699108444983Mouse
11532703Sluc43g_msusceptibility to lung cancer 43g (mouse)474444699108444983Mouse
11532704Sluc43a_msusceptibility to lung cancer 43a (mouse)474444699108444983Mouse
11532705Sluc43b_msusceptibility to lung cancer 43b (mouse)474444699108444983Mouse
11532706Sluc43c_msusceptibility to lung cancer 43c (mouse)474444699108444983Mouse
11532707Sluc43h_msusceptibility to lung cancer 43h (mouse)474444699108444983Mouse
11532708Sluc43i_msusceptibility to lung cancer 43i (mouse)474444699108444983Mouse
1301545Gauc_mglucose area under curve (mouse)Not determined476763107110763305Mouse
1300697Sle2_msystemic lupus erythmatosus susceptibility 2 (mouse)Not determined477957579111957775Mouse
11039504Ltpr4a_mLeishmania tropica response 4a (mouse)479365751113365867Mouse
11039505Ltpr4c_mLeishmania tropica response 4c (mouse)479365751113365867Mouse
11039506Ltpr4b_mLeishmania tropica response 4b (mouse)479365751113365867Mouse
11039517Ltpr4_mLeishmania tropica response 4 (mouse)479365751113365867Mouse
12904933Edlmmq3_mextensor digitorum longus muscle mass QTL 3 (mouse)481213991115213991Mouse
1302204Spm1_msplenomegaly modifier (mouse)Not determined482244395116244582Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488118237118557197Mouse
27226766Tibl17_mtibia length 17, 16 week (mouse)488518237108457197Mouse
11532738Abd1_mautoimmune biliary disease 1 (mouse)488982069116271120Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
27226760Feml19_mfemur length 19, 16 week (mouse)490888237108457197Mouse
27226782Tibl2_mtibia length 2, 5 week (mouse)490888237111257197Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
14696687Gdq1_mgrooming duration QTL 1, males (mouse)496888237111857197Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse

Markers in Region
AJ003133  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384108,614,608 - 108,614,744UniSTSGRCm38
MGSCv374108,287,213 - 108,287,349UniSTSGRCm37
Celera4106,958,794 - 106,958,930UniSTS
Cytogenetic Map4DUniSTS
Whitehead/MRC_RH41487.5UniSTS
RH124318  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384108,614,384 - 108,614,464UniSTSGRCm38
MGSCv374108,286,989 - 108,287,069UniSTSGRCm37
Celera4106,958,570 - 106,958,650UniSTS
Cytogenetic Map4DUniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000102744   ⟹   ENSMUSP00000099805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4108,436,651 - 108,472,030 (+)Ensembl
GRCm38.p6 Ensembl4108,579,454 - 108,614,833 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129931
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4108,461,288 - 108,463,240 (+)Ensembl
GRCm38.p6 Ensembl4108,604,091 - 108,606,043 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130162
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4108,436,631 - 108,452,777 (+)Ensembl
GRCm38.p6 Ensembl4108,579,434 - 108,595,580 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4108,436,620 - 108,452,636 (+)Ensembl
GRCm38.p6 Ensembl4108,579,423 - 108,595,439 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143497
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4108,445,219 - 108,445,977 (+)Ensembl
GRCm38.p6 Ensembl4108,588,022 - 108,588,780 (+)Ensembl
RefSeq Acc Id: NM_011015   ⟹   NP_035145
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394108,436,651 - 108,472,030 (+)NCBI
GRCm384108,579,454 - 108,614,833 (+)NCBI
MGSCv374108,252,059 - 108,287,438 (+)RGD
Celera4106,922,805 - 106,959,019 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035145   ⟸   NM_011015
- UniProtKB: A2A8R3 (UniProtKB/Swiss-Prot),   Q9Z1N2 (UniProtKB/Swiss-Prot),   Q8C9G3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000099805   ⟸   ENSMUST00000102744
Protein Domains
BAH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1N2-F1-model_v2 AlphaFold Q9Z1N2 1-840 view protein structure

Promoters
RGD ID:6834680
Promoter ID:MM_KWN:38909
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000075835,   ENSMUST00000102744,   NM_172697,   OTTMUST00000018730,   OTTMUST00000018731,   UC008UBG.1,   UC008UBI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364108,251,226 - 108,252,142 (-)MPROMDB
RGD ID:6884136
Promoter ID:EPDNEW_M5518
Type:multiple initiation site
Name:Orc1_1
Description:Mus musculus origin recognition complex, subunit 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384108,579,454 - 108,579,514EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1328337 AgrOrtholog
Ensembl Genes ENSMUSG00000028587 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000102744 ENTREZGENE
  ENSMUST00000102744.4 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAH_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18392 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1328337 ENTREZGENE
NCBI Gene 18392 ENTREZGENE
PANTHER CELL DIVISION CONTROL PROTEIN 6-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10763:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Orc1 PhenoGen
PROSITE BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A8R3 ENTREZGENE
  ORC1_MOUSE UniProtKB/Swiss-Prot
  Q3TPY7_MOUSE UniProtKB/TrEMBL
  Q3UR71_MOUSE UniProtKB/TrEMBL
  Q59IX2_MOUSE UniProtKB/TrEMBL
  Q8C9G3 ENTREZGENE, UniProtKB/TrEMBL
  Q8CFY7_MOUSE UniProtKB/TrEMBL
  Q9Z1N2 ENTREZGENE
UniProt Secondary A2A8R3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Orc1  origin recognition complex, subunit 1  Orc1l  origin recognition complex, subunit 1-like (S.cereviaiae)  Symbol and/or name change 5135510 APPROVED