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Gene: Ptger4 (prostaglandin E receptor 4 (subtype EP4)) Mus musculus
Symbol: Ptger4
Name: prostaglandin E receptor 4 (subtype EP4)
Description: Predicted to have prostaglandin E receptor activity. Involved in several processes, including cellular response to mechanical stimulus; regulation of cytokine secretion; and regulation of inflammatory response. Predicted to localize to several cellular components, including the neuron projection terminus; neuronal cell body; and nuclear membrane. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Is expressed in central nervous system; early conceptus; heart valve; retina; and secondary oocyte. Orthologous to human PTGER4 (prostaglandin E receptor 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EP4; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4 (EP4 subtype); prostaglandin E receptor EP4 subtype; prostaglandin E2 receptor EP4 subtype; prostanoid EP4 receptor; Ptgerep4
Homo sapiens (human) : PTGER4 (prostaglandin E receptor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptger4 (prostaglandin E receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptger4 (prostaglandin E receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGER4 (prostaglandin E receptor 4)
Canis lupus familiaris (dog) : PTGER4 (prostaglandin E receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptger4 (prostaglandin E receptor 4)
Sus scrofa (pig) : PTGER4 (prostaglandin E receptor 4)
Chlorocebus sabaeus (green monkey) : PTGER4 (prostaglandin E receptor 4)
Heterocephalus glaber (naked mole-rat) : Ptger4 (prostaglandin E receptor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl155,206,661 - 5,244,187 (-)Ensembl
GRCm38155,233,399 - 5,244,187 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37155,183,404 - 5,193,831 (-)NCBIGRCm37mm9NCBIm37
MGSCv36155,181,080 - 5,191,046 (-)NCBImm8
Celera155,082,714 - 5,093,503 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptger4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732089
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.