Hamp (hepcidin antimicrobial peptide) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Hamp (hepcidin antimicrobial peptide) Mus musculus
Analyze
Symbol: Hamp
Name: hepcidin antimicrobial peptide
RGD ID: 1550218
MGI Page MGI
Description: Enables copper ion binding activity. Involved in cellular iron ion homeostasis and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including defense response to other organism; negative regulation of bone resorption; and positive regulation of nitrogen compound metabolic process. Located in extracellular space and nucleus. Is expressed in embryo; liver; and yolk sac. Used to study hemochromatosis type 2B. Human ortholog(s) of this gene implicated in anemia; hemochromatosis; hemochromatosis type 2B; and hepatocellular carcinoma. Orthologous to human HAMP (hepcidin antimicrobial peptide).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Hamp1; Hep; Hepc; Hepc1; hepcidin; hepcidin antimicrobial peptide 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,641,793 - 30,643,454 (-)NCBIGRCm39mm39
GRCm39 Ensembl730,641,793 - 30,643,457 (-)Ensembl
GRCm38730,942,368 - 30,944,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,942,368 - 30,944,032 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,727,387 - 31,729,036 (-)NCBIGRCm37mm9NCBIm37
MGSCv36730,651,128 - 30,652,777 (-)NCBImm8
Celera725,508,433 - 25,510,082 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,10-phenanthroline  (ISO)
10-(beta-Dimethylaminopropionyl)phenothiazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2'-bipyridine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP)
2-acetamidofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,4,5,3',4',5'-Hexachlorobiphenyl  (ISO)
3,7-dihydropurine-6-thione  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
acetaldehyde  (ISO)
acrylamide  (ISO)
Actein  (ISO)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (ISO)
apomorphine  (ISO)
aristolochic acid  (ISO)
Benzamil  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
bromobenzene  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
camptothecin  (ISO)
cantharidin  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP)
CGS 15943  (ISO)
chlorpyrifos  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP)
copper(II) sulfate  (ISO)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
desferrioxamine B  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diltiazem  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP,ISO)
ferric ammonium citrate  (ISO)
flutamide  (ISO)
fomepizole  (ISO)
fructose  (ISO)
furan  (ISO)
gadolinium trichloride  (ISO)
genistein  (EXP)
hemin  (EXP)
heparin  (EXP,ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP)
iron trichloride  (ISO)
iron(0)  (EXP,ISO)
isoprenaline  (EXP,ISO)
ketoconazole  (EXP)
lansoprazole  (ISO)
lead nitrate  (EXP)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP,ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercaptopurine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metacetamol  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
mitomycin C  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nefazodone  (ISO)
niclosamide  (ISO)
nimodipine  (EXP)
nitrofen  (ISO)
nocodazole  (ISO)
omeprazole  (EXP,ISO)
ozone  (EXP)
pantoprazole  (ISO)
papaverine  (ISO)
paracetamol  (EXP,ISO)
pentacarbonyliron  (EXP)
phenethyl caffeate  (ISO)
phenformin  (ISO)
phenylephrine  (ISO)
pirinixic acid  (EXP)
pravastatin  (EXP,ISO)
protein kinase inhibitor  (ISO)
purine-6-thiol  (ISO)
quercetin  (EXP,ISO)
quinolin-8-ol  (ISO)
rabeprazole  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
Rutecarpine  (ISO)
serpentine asbestos  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium fluoride  (EXP)
streptozocin  (ISO)
sulforaphane  (EXP,ISO)
tamoxifen  (ISO)
tebuconazole  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
tributylstannane  (EXP)
triclosan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
verapamil  (EXP)
vincristine  (ISO)
vitamin D  (ISO)
vitamin E  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
aging  (ISO)
antimicrobial humoral immune response mediated by antimicrobial peptide  (ISO)
cellular iron ion homeostasis  (IBA,IDA,ISO)
cellular response to bile acid  (ISO)
cellular response to extracellular stimulus  (TAS)
cellular response to interleukin-6  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to X-ray  (ISO)
defense response to bacterium  (IBA,IDA,IMP)
defense response to fungus  (IDA,ISO)
defense response to Gram-negative bacterium  (ISO)
defense response to Gram-positive bacterium  (ISO)
iron ion homeostasis  (IDA,IMP)
killing of cells of other organism  (ISO)
liver regeneration  (ISO)
multicellular organismal iron ion homeostasis  (ISO)
myeloid cell homeostasis  (IMP)
negative regulation of bone resorption  (IMP)
negative regulation of inflammatory response  (IGI)
negative regulation of intestinal absorption  (ISO)
negative regulation of ion transmembrane transporter activity  (ISO)
negative regulation of iron export across plasma membrane  (ISO)
negative regulation of iron ion transmembrane transport  (IBA,IGI)
negative regulation of iron ion transmembrane transporter activity  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP)
positive regulation of cell growth involved in cardiac muscle cell development  (ISO)
positive regulation of cellular protein catabolic process  (IDA)
positive regulation of macrophage activation  (IMP)
positive regulation of protein polyubiquitination  (ISO)
positive regulation of receptor catabolic process  (ISO)
positive regulation of receptor internalization  (ISO)
positive regulation of transcription by RNA polymerase II  (IGI)
receptor signaling pathway via JAK-STAT  (IDA)
response to erythropoietin  (ISO)
response to ethanol  (ISO)
response to iron ion  (ISO)
response to iron ion starvation  (ISO)
response to vitamin A  (ISO)
response to zinc ion  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Andreani M, etal., Haematologica. 2009 Sep;94(9):1293-6. doi: 10.3324/haematol.2009.006270.
2. Arruda SF, etal., Nutrition. 2009 Apr;25(4):472-8. doi: 10.1016/j.nut.2008.11.030. Epub 2009 Feb 12.
3. Ashby DR, etal., Kidney Int. 2009 May;75(9):976-81. doi: 10.1038/ki.2009.21. Epub 2009 Feb 11.
4. Bartnikas TB, etal., Blood. 2011 Jan 13;117(2):630-7. doi: 10.1182/blood-2010-05-287359. Epub 2010 Oct 18.
5. Ben-Assa E, etal., Toxicol Lett. 2009 Sep 28;189(3):242-7. doi: 10.1016/j.toxlet.2009.06.848. Epub 2009 Jun 12.
6. Broderius M, etal., Genes Nutr. 2012 Jul;7(3):405-14. doi: 10.1007/s12263-012-0293-7. Epub 2012 Mar 29.
7. Casals-Pascual C, etal., Haematologica. 2012 Nov;97(11):1695-8. doi: 10.3324/haematol.2012.065854. Epub 2012 Jun 11.
8. Ding H, etal., PLoS One. 2011;6(9):e25324. doi: 10.1371/journal.pone.0025324. Epub 2011 Sep 21.
9. Divakaran V, etal., Am J Hematol. 2011 Jan;86(1):107-9. doi: 10.1002/ajh.21902.
10. Drakesmith H, etal., Cell Metab. 2015 Nov 3;22(5):777-87. doi: 10.1016/j.cmet.2015.09.006. Epub 2015 Oct 1.
11. Fernandes JC, etal., Biomed Res Int. 2014;2014:421304. doi: 10.1155/2014/421304. Epub 2014 Dec 18.
12. Gardenghi S, etal., Blood. 2007 Jun 1;109(11):5027-35. Epub 2007 Feb 13.
13. Gardenghi S, etal., Blood. 2014 Feb 20;123(8):1137-45. doi: 10.1182/blood-2013-08-521625. Epub 2013 Dec 19.
14. Gotardo EM, etal., World J Gastroenterol. 2014 Apr 21;20(15):4345-52. doi: 10.3748/wjg.v20.i15.4345.
15. Handa P, etal., Ann Hepatol. 2017 Jan-Feb 2017;16(1):77-85. doi: 10.5604/16652681.1226818.
16. Huang YH, etal., Lab Invest. 2009 Oct;89(10):1128-39. doi: 10.1038/labinvest.2009.82. Epub 2009 Aug 3.
17. Isoda M, etal., J Nutr Biochem. 2010 Aug;21(8):749-56. doi: 10.1016/j.jnutbio.2009.04.009. Epub 2009 Jul 16.
18. Izawa T, etal., Exp Toxicol Pathol. 2014 Mar;66(2-3):155-62. doi: 10.1016/j.etp.2013.12.002. Epub 2013 Dec 25.
19. Le Guenno G, etal., Diabetes Res Clin Pract. 2007 Mar 8;.
20. Liu YQ, etal., Int J Sport Nutr Exerc Metab. 2011 Feb;21(1):19-26.
21. Marmur J, etal., BMC Gastroenterol. 2018 Jun 5;18(1):78. doi: 10.1186/s12876-018-0804-0.
22. Mei S, etal., Int J Hematol. 2014 Sep;100(3):266-73. doi: 10.1007/s12185-014-1626-7. Epub 2014 Jul 23.
23. MGD data from the GO Consortium
24. Naito Y, etal., Int J Cardiol. 2014 Mar 1;172(1):e45-7. doi: 10.1016/j.ijcard.2013.12.067. Epub 2013 Dec 28.
25. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
26. OMIM Disease Annotation Pipeline
27. Pigeon C, etal., J Biol Chem 2001 Mar 16;276(11):7811-9.
28. Pratummo K, etal., Hematology. 2014 Apr;19(3):175-80. doi: 10.1179/1607845413Y.0000000110. Epub 2013 Nov 25.
29. RGD automated import pipeline
30. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
31. RGD automated import pipeline for gene-chemical interactions
32. Roetto A, etal., Nat Genet. 2003 Jan;33(1):21-2. Epub 2002 Dec 9.
33. Roy CN, etal., Blood. 2007 May 1;109(9):4038-44. Epub 2007 Jan 11.
34. Schwarz P, etal., Gut. 2012 Feb;61(2):193-201. doi: 10.1136/gut.2011.241208. Epub 2011 Jul 13.
35. Srai SK, etal., Kidney Int. 2010 Oct;78(7):660-7. doi: 10.1038/ki.2010.217. Epub 2010 Jul 14.
36. Theurl I, etal., Blood. 2011 Nov 3;118(18):4977-84. doi: 10.1182/blood-2011-03-345066. Epub 2011 Jul 5.
37. Theurl M, etal., Haematologica. 2014 Sep;99(9):1516-24. doi: 10.3324/haematol.2013.099481. Epub 2014 Jun 3.
38. Udali S, etal., Eur J Clin Invest. 2018 Feb;48(2):e12870. doi: 10.1111/eci.12870. Epub 2017 Dec 28.
39. Wang QM, etal., World J Gastroenterol. 2013 May 21;19(19):2921-34. doi: 10.3748/wjg.v19.i19.2921.
40. Xu L, etal., Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 Nov;39(6):936-9.
41. Yuki KE, etal., PLoS One. 2013;8(2):e55331. doi: 10.1371/journal.pone.0055331. Epub 2013 Feb 4.
Additional References at PubMed
PMID:2995362   PMID:11113131   PMID:11447267   PMID:11930010   PMID:11985602   PMID:12393428   PMID:12477932   PMID:12704388   PMID:12704390   PMID:12729891   PMID:14564671   PMID:14604961  
PMID:14656876   PMID:14751922   PMID:15003819   PMID:15124018   PMID:15131800   PMID:15158327   PMID:15315977   PMID:15342464   PMID:15358563   PMID:15489334   PMID:15514116   PMID:15665091  
PMID:15684062   PMID:15793843   PMID:15914561   PMID:15932798   PMID:16081696   PMID:16141345   PMID:16239432   PMID:16330325   PMID:16339690   PMID:16574947   PMID:16648237   PMID:16737972  
PMID:16787915   PMID:16799992   PMID:16801541   PMID:17241879   PMID:17264297   PMID:17316628   PMID:17331161   PMID:17435114   PMID:17644736   PMID:17689119   PMID:17932563   PMID:18042040  
PMID:18316026   PMID:18451267   PMID:18521557   PMID:18539898   PMID:18653481   PMID:18664504   PMID:18800028   PMID:18948155   PMID:18991290   PMID:18997172   PMID:19008338   PMID:19059700  
PMID:19204324   PMID:19249912   PMID:19252486   PMID:19371723   PMID:19414861   PMID:19426170   PMID:19587376   PMID:19596281   PMID:19679815   PMID:19751239   PMID:19786029   PMID:19824072  
PMID:19898775   PMID:19924283   PMID:20053755   PMID:20065295   PMID:20113314   PMID:20169331   PMID:20177050   PMID:20219396   PMID:20338170   PMID:20511664   PMID:20530874   PMID:20562862  
PMID:20634490   PMID:20682319   PMID:20811044   PMID:21059897   PMID:21078691   PMID:21303570   PMID:21408141   PMID:21480335   PMID:21601942   PMID:21628413   PMID:21700773   PMID:21703414  
PMID:21841161   PMID:21873546   PMID:21873635   PMID:21907140   PMID:21993681   PMID:22045566   PMID:22084434   PMID:22128145   PMID:22144676   PMID:22207682   PMID:22264719   PMID:22383698  
PMID:22461476   PMID:22490684   PMID:22544439   PMID:22611157   PMID:22847740   PMID:22869521   PMID:22960056   PMID:22967998   PMID:22990014   PMID:23114598   PMID:23160767   PMID:23438894  
PMID:23502961   PMID:23578384   PMID:23615502   PMID:23637785   PMID:23656253   PMID:23700338   PMID:23836059   PMID:23846698   PMID:23945155   PMID:23996485   PMID:24044515   PMID:24045836  
PMID:24123375   PMID:24204002   PMID:24252754   PMID:24357728   PMID:24361124   PMID:24387766   PMID:24409331   PMID:24418880   PMID:24454764   PMID:24497831   PMID:24561287   PMID:24646470  
PMID:24652331   PMID:24904115   PMID:24904118   PMID:24970260   PMID:24973448   PMID:25096756   PMID:25124681   PMID:25232250   PMID:25264597   PMID:25713362   PMID:25860887   PMID:25904410  
PMID:26293821   PMID:26302924   PMID:26506980   PMID:26515063   PMID:26635037   PMID:26755707   PMID:26944476   PMID:27067488   PMID:27072365   PMID:27154187   PMID:27325674   PMID:27423740  
PMID:27440777   PMID:27483343   PMID:27576776   PMID:27667162   PMID:27686598   PMID:27733366   PMID:27741349   PMID:27864295   PMID:27884972   PMID:27897970   PMID:27903526   PMID:27903529  
PMID:28057442   PMID:28135344   PMID:28187515   PMID:28405918   PMID:28438754   PMID:28465342   PMID:28507548   PMID:28583802   PMID:28798083   PMID:28864813   PMID:28864822   PMID:29021231  
PMID:29073189   PMID:29089902   PMID:29158088   PMID:29217822   PMID:29324800   PMID:29575577   PMID:29600572   PMID:29636509   PMID:29749404   PMID:29752985   PMID:29903760   PMID:30097509  
PMID:30213871   PMID:30227271   PMID:30352047   PMID:30478858   PMID:30538134   PMID:30559294   PMID:30586758   PMID:30587002   PMID:30610968   PMID:30724105   PMID:30733279   PMID:30888356  
PMID:31001931   PMID:31172340   PMID:31287995   PMID:31600168   PMID:31601421   PMID:31634395   PMID:31761321   PMID:31800957   PMID:31812496   PMID:32108988   PMID:32273468   PMID:32374849  
PMID:32542311   PMID:32827218   PMID:32958690   PMID:33640761   PMID:33820875   PMID:34063414   PMID:34188052  


Genomics

Comparative Map Data
Hamp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,641,793 - 30,643,454 (-)NCBIGRCm39mm39
GRCm39 Ensembl730,641,793 - 30,643,457 (-)Ensembl
GRCm38730,942,368 - 30,944,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,942,368 - 30,944,032 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,727,387 - 31,729,036 (-)NCBIGRCm37mm9NCBIm37
MGSCv36730,651,128 - 30,652,777 (-)NCBImm8
Celera725,508,433 - 25,510,082 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.27NCBI
HAMP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1935,280,716 - 35,285,143 (+)EnsemblGRCh38hg38GRCh38
GRCh381935,282,528 - 35,285,143 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371935,773,431 - 35,776,046 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,465,250 - 40,467,886 (+)NCBINCBI36hg18NCBI36
Build 341940,465,249 - 40,467,883NCBI
Celera1932,486,848 - 32,489,484 (+)NCBI
Cytogenetic Map19q13.12NCBI
HuRef1932,282,038 - 32,284,542 (+)NCBIHuRef
CHM1_11935,775,030 - 35,777,667 (+)NCBICHM1_1
Hamp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2186,170,926 - 86,172,865 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl186,170,901 - 86,172,891 (-)Ensembl
Rnor_6.0189,368,021 - 89,369,960 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,368,021 - 89,369,960 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,523,506 - 90,525,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,978,120 - 85,980,059 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,056,230 - 86,058,170 (-)NCBI
Celera180,539,771 - 80,541,710 (-)NCBICelera
Cytogenetic Map1q21NCBI
Hamp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,575,510 - 4,577,649 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554684,576,080 - 4,577,591 (+)NCBIChiLan1.0ChiLan1.0
HAMP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11940,964,445 - 40,968,861 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,964,445 - 40,968,861 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01932,228,701 - 32,231,494 (+)NCBIMhudiblu_PPA_v0panPan3
HAMP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,305,531 - 117,306,587 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,305,411 - 117,306,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,708,503 - 116,709,559 (-)NCBI
ROS_Cfam_1.01117,905,446 - 117,906,502 (-)NCBI
UMICH_Zoey_3.11117,468,198 - 117,469,254 (-)NCBI
UNSW_CanFamBas_1.01117,094,052 - 117,095,108 (-)NCBI
UU_Cfam_GSD_1.01118,149,597 - 118,150,653 (-)NCBI
LOC101972117
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,634,907 - 10,636,644 (+)NCBI
SpeTri2.0NW_0049365701,009,344 - 1,010,654 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAMP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,784,159 - 44,787,307 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,785,863 - 44,787,303 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,205,859 - 40,207,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234503
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,214,820 - 30,218,100 (+)NCBI
ChlSab1.1 Ensembl630,215,563 - 30,217,996 (+)Ensembl
Vero_WHO_p1.0NW_0236660737,989,379 - 7,992,640 (+)NCBI
Hamp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247948,257,760 - 8,259,243 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7269777136697919Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7346321287493512Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360000072900000Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined71028944244289559Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71060637344606511Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71278145246781452Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71278145246781452Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1333306047333196Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71343577947435779Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71360000047700000Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71690336849509583Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71899486940024609Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71958059053580679Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined72014282554142942Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72302446357024609Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72323914857239292Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72341710757417107Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72719819161202351Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72760637337142942Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72789112561891125Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3033306081485905Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730500000109400000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir122mmu-miR-122-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)21364282

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:177
Interacting mature miRNAs:181
Transcripts:ENSMUST00000062620
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000062620   ⟹   ENSMUSP00000055404
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl730,641,793 - 30,643,457 (-)Ensembl
GRCm38.p6 Ensembl730,942,368 - 30,944,032 (-)Ensembl
RefSeq Acc Id: NM_032541   ⟹   NP_115930
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39730,641,793 - 30,643,454 (-)NCBI
GRCm38730,942,368 - 30,944,029 (-)NCBI
MGSCv37731,727,387 - 31,729,036 (-)RGD
Celera725,508,433 - 25,510,082 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_115930 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG49293 (Get FASTA)   NCBI Sequence Viewer  
  AAH21587 (Get FASTA)   NCBI Sequence Viewer  
  AAM27440 (Get FASTA)   NCBI Sequence Viewer  
  Q9EQ21 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_115930   ⟸   NM_032541
- Peptide Label: preproprotein
- UniProtKB: Q9EQ21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000055404   ⟸   ENSMUST00000062620

Promoters
RGD ID:8663537
Promoter ID:EPDNEW_M9800
Type:multiple initiation site
Name:Hamp_1
Description:Mus musculus hepcidin antimicrobial peptide , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38730,944,029 - 30,944,089EPDNEW
RGD ID:6841273
Promoter ID:MM_KWN:49874
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   MEF_B6
Transcripts:NM_032541
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36731,728,856 - 31,729,607 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1933533 AgrOrtholog
Ensembl Genes ENSMUSG00000050440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000055404 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000062620 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Hepcidin UniProtKB/Swiss-Prot
KEGG Report mmu:84506 UniProtKB/Swiss-Prot
MGD MGI:1933533 ENTREZGENE
NCBI Gene 84506 ENTREZGENE
PANTHER PTHR16877 UniProtKB/Swiss-Prot
Pfam Hepcidin UniProtKB/Swiss-Prot
PhenoGen Hamp PhenoGen
UniProt HEPC_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE