| Gene: Pgpep1 (pyroglutamyl-peptidase I) Mus musculus |
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Analyze |
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| Symbol: |
Pgpep1 |
| Name: |
pyroglutamyl-peptidase I |
| Description: |
null |
| Type: |
protein-coding
|
| RefSeq Status: |
VALIDATED |
| Also known as: |
2810003H13Rik; 5-oxoprolyl-peptidase; Gm19458; PAP-I; Pcp; PGP; PGP-I; PGPI; predicted gene, 19458; putative pyroglutamyl-peptidase I; pyroglutamyl aminopeptidase I; pyroglutamyl-peptidase 1; pyrrolidone-carboxylate peptidase |
| Orthologs: |
| Species |
Gene symbol and name |
Data Source |
Assertion derived from |
less info ...
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| Orthologs 1 |
| Homo sapiens (human): |
PGPEP1 (pyroglutamyl-peptidase I) |
HGNC |
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam |
| Rattus norvegicus (Norway rat): |
Pgpep1 (pyroglutamyl-peptidase I) |
HGNC |
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl |
| Chinchilla lanigera (long-tailed chinchilla): |
Pgpep1 (pyroglutamyl-peptidase I) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Pan paniscus (bonobo/pygmy chimpanzee): |
PGPEP1 (pyroglutamyl-peptidase I) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Canis lupus familiaris (dog): |
PGPEP1 (pyroglutamyl-peptidase I) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Ictidomys tridecemlineatus (thirteen-lined ground squirrel): |
Pgpep1 (pyroglutamyl-peptidase I) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Sus scrofa (pig): |
PGPEP1 (pyroglutamyl-peptidase I) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Other homologs 2 |
| Homo sapiens (human): |
PGPEP1L (pyroglutamyl-peptidase I like) |
HGNC |
OrthoDB |
| Alliance orthologs 3 |
| Rattus norvegicus (Norway rat): |
Pgpep1 (pyroglutamyl-peptidase I)
|
Alliance |
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam) |
| Homo sapiens (human): |
PGPEP1 (pyroglutamyl-peptidase I)
|
Alliance |
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam) |
| Danio rerio (zebrafish): |
pgpep1 (pyroglutamyl-peptidase I)
|
Alliance |
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam) |
| Caenorhabditis elegans (roundworm): |
F16H6.4
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Alliance |
DIOPT (PANTHER, PhylomeDB, TreeFam) |
| Drosophila melanogaster (fruit fly): |
CG32147
|
Alliance |
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam) |
| Caenorhabditis elegans (roundworm): |
F16H6.7
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Alliance |
DIOPT (PANTHER, PhylomeDB, TreeFam) |
| Caenorhabditis elegans (roundworm): |
F35F10.7
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Alliance |
DIOPT (PANTHER, PhylomeDB, TreeFam) |
| Caenorhabditis elegans (roundworm): |
M04C9.1
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Alliance |
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam) |
| Caenorhabditis elegans (roundworm): |
M04C9.2
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Alliance |
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam) |
| Caenorhabditis elegans (roundworm): |
M04C9.3
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Alliance |
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam) |
| Caenorhabditis elegans (roundworm): |
W04E12.7
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Alliance |
DIOPT (PANTHER, PhylomeDB, TreeFam) |
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| Latest Assembly: |
GRCm38 - Mouse Genome Assembly GRCm38 |
| Position: |
| Mouse Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
GRCm38 | 8 | 70,646,436 - 70,659,856 (-) | NCBI | GRCm38 | GRCm38 | mm10 | GRCm38 | MGSCv37 | 8 | 73,173,010 - 73,183,580 (-) | NCBI | GRCm37 | | mm9 | NCBIm37 | MGSCv36 | 8 | 73,578,100 - 73,588,670 (-) | NCBI | | | mm8 | | Celera | 8 | 73,203,198 - 73,216,496 (-) | NCBI | | Celera | | | Cytogenetic Map | 8 | B3.3 | NCBI | | | | |
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| JBrowse: |
View Region in Genome Browser (JBrowse)
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| Model |
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 Gene-Chemical Interaction Annotations
| 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of PGPEP1 mRNA | CTD | PMID:26682919 | | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of PGPEP1 mRNA | CTD | PMID:17555576 | | 17beta-estradiol | increases expression | ISO | RGD:1348411 | 6480464 | Estradiol results in increased expression of PGPEP1 mRNA | CTD | PMID:23019147 | | 17beta-estradiol | multiple interactions | ISO | RGD:1348411 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PGPEP1 mRNA | CTD | PMID:30165855 | | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PGPEP1 mRNA | CTD | PMID:21570461 | | 2,4-dinitrotoluene | affects expression | ISO | RGD:1303133 | 6480464 | 2, 4-dinitrotoluene affects the expression of PGPEP1 mRNA | CTD | PMID:21346803 | | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of PGPEP1 mRNA | CTD | PMID:28973697 | | acrylamide | decreases expression | ISO | RGD:1303133 | 6480464 | Acrylamide results in decreased expression of PGPEP1 mRNA | CTD | PMID:28959563 | | aflatoxin B1 | decreases methylation | ISO | RGD:1348411 | 6480464 | Aflatoxin B1 results in decreased methylation of PGPEP1 intron | CTD | PMID:30157460 | | all-trans-retinoic acid | increases expression | ISO | RGD:1303133 | 6480464 | Tretinoin results in increased expression of PGPEP1 mRNA | CTD | PMID:20488242 | | all-trans-retinoic acid | increases expression | ISO | RGD:1348411 | 6480464 | Tretinoin results in increased expression of PGPEP1 mRNA | CTD | PMID:23724009 | | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of PGPEP1 mRNA | CTD | PMID:23650126 | | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PGPEP1 mRNA | CTD | PMID:22610609 | | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of PGPEP1 mRNA | CTD | PMID:26377693 | | beta-naphthoflavone | multiple interactions | ISO | RGD:1303133 | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA | CTD | PMID:18164116 | | bisphenol A | increases expression | ISO | RGD:1303133 | 6480464 | bisphenol A results in increased expression of PGPEP1 mRNA | CTD | PMID:25181051 | | bisphenol A | increases expression | ISO | RGD:1348411 | 6480464 | bisphenol A results in increased expression of PGPEP1 mRNA | CTD | PMID:25047013, PMID:27685785 | | calcitriol | increases expression | ISO | RGD:1348411 | 6480464 | Calcitriol results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | | calcitriol | multiple interactions | ISO | RGD:1348411 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes, Carbon analog results in decreased expression of PGPEP1 mRNA, Nanotubes, Carbon results in decreased expression of PGPEP1 mRNA | CTD | PMID:25620056 | | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | | cisplatin | multiple interactions | ISO | RGD:1348411 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PGPEP1 mRNA | CTD | PMID:27392435 | | copper(II) sulfate | decreases expression | ISO | RGD:1348411 | 6480464 | Copper Sulfate results in decreased expression of PGPEP1 mRNA | CTD | PMID:19549813 | | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PGPEP1 mRNA | CTD | PMID:19770486 | | dibenz[a,h]anthracene | increases expression | EXP | | 6480464 | 1 more ... | CTD | PMID:26377693 | | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PGPEP1 mRNA | CTD | PMID:17361019, PMID:21266533 | | ethyl methanesulfonate | increases expression | ISO | RGD:1348411 | 6480464 | Ethyl Methanesulfonate results in increased expression of PGPEP1 mRNA | CTD | PMID:23649840 | | finasteride | increases expression | ISO | RGD:1303133 | 6480464 | Finasteride results in increased expression of PGPEP1 mRNA | CTD | PMID:24136188 | | flutamide | decreases expression | ISO | RGD:1303133 | 6480464 | Flutamide results in decreased expression of PGPEP1 mRNA | CTD | PMID:24136188 | | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | | genistein | increases expression | ISO | RGD:1348411 | 6480464 | Genistein results in increased expression of PGPEP1 mRNA | CTD | PMID:23019147 | | ketamine | decreases expression | ISO | RGD:1303133 | 6480464 | Ketamine results in decreased expression of PGPEP1 mRNA | CTD | PMID:20080153 | | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:1348411 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PGPEP1 mRNA | CTD | PMID:24810058 | | N-nitrosodiethylamine | multiple interactions | ISO | RGD:1303133 | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA | CTD | PMID:18164116 | | nefazodone | decreases expression | ISO | RGD:1303133 | 6480464 | nefazodone results in decreased expression of PGPEP1 mRNA | CTD | PMID:24136188 | | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PGPEP1 mRNA | CTD | PMID:17562736 | | paracetamol | decreases expression | ISO | RGD:1348411 | 6480464 | Acetaminophen results in decreased expression of PGPEP1 mRNA | CTD | PMID:21420995 | | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of PGPEP1 mRNA | CTD | PMID:18445702, PMID:23811191 | | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of PGPEP1 protein | CTD | PMID:25505154 | | silicon dioxide | decreases expression | ISO | RGD:1348411 | 6480464 | Silicon Dioxide results in decreased expression of PGPEP1 mRNA | CTD | PMID:25351596 | | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of PGPEP1 mRNA | CTD | PMID:17555576, PMID:20937368 | | testosterone | multiple interactions | ISO | RGD:1348411 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | | testosterone | increases expression | ISO | RGD:1348411 | 6480464 | Testosterone results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of PGPEP1 mRNA | CTD | PMID:20403060 | | thimerosal | decreases expression | ISO | RGD:1348411 | 6480464 | Thimerosal results in decreased expression of PGPEP1 mRNA | CTD | PMID:27188386 | | trichostatin A | affects expression | ISO | RGD:1348411 | 6480464 | trichostatin A affects the expression of PGPEP1 mRNA | CTD | PMID:28542535 | | valproic acid | decreases expression | ISO | RGD:1348411 | 6480464 | Valproic Acid results in decreased expression of PGPEP1 mRNA | CTD | PMID:23527032 | | valproic acid | increases expression | ISO | RGD:1348411 | 6480464 | Valproic Acid results in increased expression of PGPEP1 mRNA | CTD | PMID:19101580 more ... | | vinclozolin | decreases expression | ISO | RGD:1303133 | 6480464 | vinclozolin results in decreased expression of PGPEP1 mRNA | CTD | PMID:23034163 | |
