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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of PGPEP1 mRNA | CTD | PMID:26682919 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of PGPEP1 mRNA | CTD | PMID:17555576 | 17beta-estradiol | increases expression | ISO | RGD:1348411 | 6480464 | Estradiol results in increased expression of PGPEP1 mRNA | CTD | PMID:23019147 | 17beta-estradiol | multiple interactions | ISO | RGD:1348411 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PGPEP1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PGPEP1 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | ISO | RGD:1303133 | 6480464 | 2, 4-dinitrotoluene affects the expression of PGPEP1 mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | RGD:1303133 | 6480464 | [3 more ... | CTD | PMID:30744511 | 3,4,5,3',4',5'-Hexachlorobiphenyl | multiple interactions | ISO | RGD:1303133 | 6480464 | [3 more ... | CTD | PMID:30744511 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of PGPEP1 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | ISO | RGD:1303133 | 6480464 | acetamide results in decreased expression of PGPEP1 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | RGD:1303133 | 6480464 | Acrylamide results in decreased expression of PGPEP1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1348411 | 6480464 | Aflatoxin B1 results in decreased methylation of PGPEP1 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RGD:1303133 | 6480464 | Tretinoin results in increased expression of PGPEP1 mRNA | CTD | PMID:20488242 | all-trans-retinoic acid | increases expression | ISO | RGD:1348411 | 6480464 | Tretinoin results in increased expression of PGPEP1 mRNA | CTD | PMID:23724009 | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl 54% Chlorine results in increased expression of PGPEP1 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzoapyrene results in increased expression of PGPEP1 mRNA | CTD | PMID:22610609 | benzo[a]pyrene | decreases expression | ISO | RGD:1348411 | 6480464 | Benzoapyrene results in decreased expression of PGPEP1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1348411 | 6480464 | Benzoapyrene affects the methylation of PGPEP1 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzobfluoranthene results in increased expression of PGPEP1 mRNA | CTD | PMID:26377693 | beta-naphthoflavone | multiple interactions | ISO | RGD:1303133 | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA | CTD | PMID:18164116 | bisphenol A | increases expression | ISO | RGD:1303133 | 6480464 | bisphenol A results in increased expression of PGPEP1 mRNA | CTD | PMID:25181051 | bisphenol A | affects expression | ISO | RGD:1303133 | 6480464 | bisphenol A affects the expression of PGPEP1 mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | ISO | RGD:1348411 | 6480464 | bisphenol A results in increased expression of PGPEP1 mRNA | CTD | PMID:25047013, PMID:27685785 | calcitriol | increases expression | ISO | RGD:1348411 | 6480464 | Calcitriol results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | RGD:1348411 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | RGD:1348411 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PGPEP1 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | RGD:1348411 | 6480464 | Copper Sulfate results in decreased expression of PGPEP1 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PGPEP1 mRNA | CTD | PMID:19770486 | dibenz[a,h]anthracene | increases expression | EXP | | 6480464 | 1 more ... | CTD | PMID:26377693 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PGPEP1 mRNA | CTD | PMID:17361019, PMID:21266533 | ethyl methanesulfonate | increases expression | ISO | RGD:1348411 | 6480464 | Ethyl Methanesulfonate results in increased expression of PGPEP1 mRNA | CTD | PMID:23649840 | finasteride | increases expression | ISO | RGD:1303133 | 6480464 | Finasteride results in increased expression of PGPEP1 mRNA | CTD | PMID:24136188 | flutamide | decreases expression | ISO | RGD:1303133 | 6480464 | Flutamide results in decreased expression of PGPEP1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of PGPEP1 mRNA | CTD | PMID:25629700 | genistein | increases expression | ISO | RGD:1348411 | 6480464 | Genistein results in increased expression of PGPEP1 mRNA | CTD | PMID:23019147 | ketamine | decreases expression | ISO | RGD:1303133 | 6480464 | Ketamine results in decreased expression of PGPEP1 mRNA | CTD | PMID:20080153 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PGPEP1 gene | CTD | PMID:20938992 | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:1348411 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PGPEP1 mRNA | CTD | PMID:24810058 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:1303133 | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA | CTD | PMID:18164116 | nefazodone | decreases expression | ISO | RGD:1303133 | 6480464 | nefazodone results in decreased expression of PGPEP1 mRNA | CTD | PMID:24136188 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PGPEP1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | RGD:1348411 | 6480464 | Acetaminophen results in decreased expression of PGPEP1 mRNA | CTD | PMID:21420995 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of PGPEP1 mRNA | CTD | PMID:18445702, PMID:23811191 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of PGPEP1 protein | CTD | PMID:25505154 | silicon dioxide | decreases expression | ISO | RGD:1348411 | 6480464 | Silicon Dioxide results in decreased expression of PGPEP1 mRNA | CTD | PMID:25351596 | sunitinib | increases expression | ISO | RGD:1348411 | 6480464 | Sunitinib results in increased expression of PGPEP1 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of PGPEP1 mRNA | CTD | PMID:17555576, PMID:20937368 | testosterone | multiple interactions | ISO | RGD:1348411 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | RGD:1348411 | 6480464 | Testosterone results in increased expression of PGPEP1 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of PGPEP1 mRNA | CTD | PMID:20403060 | tetrachloromethane | decreases expression | ISO | RGD:1303133 | 6480464 | Carbon Tetrachloride results in decreased expression of PGPEP1 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PGPEP1 mRNA | CTD | PMID:31919559 | thimerosal | decreases expression | ISO | RGD:1348411 | 6480464 | Thimerosal results in decreased expression of PGPEP1 mRNA | CTD | PMID:27188386 | trichostatin A | affects expression | ISO | RGD:1348411 | 6480464 | trichostatin A affects the expression of PGPEP1 mRNA | CTD | PMID:28542535 | valproic acid | decreases expression | ISO | RGD:1348411 | 6480464 | Valproic Acid results in decreased expression of PGPEP1 mRNA | CTD | PMID:23527032 | valproic acid | increases expression | ISO | RGD:1348411 | 6480464 | Valproic Acid results in increased expression of PGPEP1 mRNA | CTD | PMID:19101580 more ... | vinclozolin | decreases expression | ISO | RGD:1303133 | 6480464 | vinclozolin results in decreased expression of PGPEP1 mRNA | CTD | PMID:23034163 | |