Pgpep1 (pyroglutamyl-peptidase I) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Pgpep1 (pyroglutamyl-peptidase I) Mus musculus
Analyze
Symbol: Pgpep1
Name: pyroglutamyl-peptidase I
RGD ID: 1552850
MGI Page MGI
Description: Predicted to enable peptidase activity. Predicted to be involved in protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol. Is expressed in central nervous system; genitourinary system; gut; lung; and submandibular gland primordium. Orthologous to human PGPEP1 (pyroglutamyl-peptidase I).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810003H13Rik; 5-oxoprolyl-peptidase; Gm19458; P; PAP-I; Pcp; PG; PGP; PGP-I; PGPI; predicted gene, 19458; putative pyroglutamyl-peptidase I; pyroglutamyl aminopeptidase I; pyroglutamyl-peptidase 1; pyrrolidone-carboxylate peptidase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,099,086 - 71,113,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,099,085 - 71,113,038 (-)EnsemblGRCm39 Ensembl
GRCm38870,646,436 - 70,660,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,646,435 - 70,660,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,173,010 - 73,183,580 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,578,100 - 73,588,670 (-)NCBIMGSCv36mm8
Celera873,205,873 - 73,216,439 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4,5,3',4',5'-Hexachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlormequat chloride  (ISO)
choline  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP)
dibenz[a,h]anthracene  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethylselenide  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
genistein  (ISO)
gentamycin  (ISO)
ketamine  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP)
reactive oxygen species  (ISO)
resveratrol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12651114   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:27113764  


Genomics

Comparative Map Data
Pgpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,099,086 - 71,113,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,099,085 - 71,113,038 (-)EnsemblGRCm39 Ensembl
GRCm38870,646,436 - 70,660,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,646,435 - 70,660,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,173,010 - 73,183,580 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,578,100 - 73,588,670 (-)NCBIMGSCv36mm8
Celera873,205,873 - 73,216,439 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
PGPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,340,598 - 18,369,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,340,598 - 18,369,950 (+)EnsemblGRCh38hg38GRCh38
GRCh371918,451,408 - 18,480,760 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,312,408 - 18,341,763 (+)NCBINCBI36Build 36hg18NCBI36
Build 341918,312,449 - 18,338,156NCBI
Celera1918,353,176 - 18,382,554 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,015,122 - 18,044,514 (+)NCBIHuRef
CHM1_11918,451,669 - 18,480,994 (+)NCBICHM1_1
T2T-CHM13v2.01918,474,715 - 18,504,090 (+)NCBIT2T-CHM13v2.0
Pgpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,804,408 - 18,817,466 (+)NCBIGRCr8
mRatBN7.21618,770,563 - 18,782,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,812,708 - 18,822,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,945,640 - 19,955,013 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,865,663 - 18,875,020 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,521,989 - 20,531,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,379,057 - 20,388,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,276,650 - 19,285,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,276,652 - 19,285,272 (+)NCBI
Celera1618,962,969 - 18,971,980 (+)NCBICelera
Cytogenetic Map16p14NCBI
Pgpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,138,393 - 3,148,331 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,138,393 - 3,148,321 (-)NCBIChiLan1.0ChiLan1.0
PGPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,201,216 - 23,230,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,209,543 - 22,255,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,819,337 - 17,848,683 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,792,335 - 18,819,031 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,792,341 - 18,812,697 (+)Ensemblpanpan1.1panPan2
PGPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,666,250 - 44,695,823 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,578,117 - 44,611,462 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,149,943 - 45,182,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,149,948 - 45,181,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,387,041 - 44,420,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,797,168 - 44,830,716 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,072,579 - 45,106,156 (-)NCBIUU_Cfam_GSD_1.0
Pgpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,319,958 - 203,343,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,869,106 - 2,892,342 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,869,100 - 2,892,342 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,451,150 - 59,485,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,448,110 - 59,485,809 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PGPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,818,743 - 16,837,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,818,643 - 16,836,949 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,503,594 - 2,532,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,610,335 - 1,622,955 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,610,325 - 1,623,189 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pgpep1
323 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1558
Count of miRNA genes:695
Interacting mature miRNAs:862
Transcripts:ENSMUST00000070173
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
11039503Ccc4_mcolitis susceptibility in the Collaborative Cross 4 (mouse)86517423778002730Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_023217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC166931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ278829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY313315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000070173   ⟹   ENSMUSP00000070778
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,099,085 - 71,112,388 (-)Ensembl
GRCm38.p6 Ensembl870,646,435 - 70,659,738 (-)Ensembl
Ensembl Acc Id: ENSMUST00000209768   ⟹   ENSMUSP00000148141
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,400 - 71,112,318 (-)Ensembl
GRCm38.p6 Ensembl870,650,750 - 70,659,668 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210193   ⟹   ENSMUSP00000148163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,954 - 71,113,038 (-)Ensembl
GRCm38.p6 Ensembl870,651,304 - 70,660,388 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210307   ⟹   ENSMUSP00000147879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,276 - 71,112,301 (-)Ensembl
GRCm38.p6 Ensembl870,650,626 - 70,659,651 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210459
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,235 - 71,111,562 (-)Ensembl
GRCm38.p6 Ensembl870,650,585 - 70,658,912 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210786   ⟹   ENSMUSP00000148241
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,974 - 71,110,088 (-)Ensembl
GRCm38.p6 Ensembl870,651,324 - 70,657,438 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211526
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,103,125 - 71,108,029 (-)Ensembl
GRCm38.p6 Ensembl870,650,475 - 70,655,379 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211715   ⟹   ENSMUSP00000148119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,102,828 - 71,112,301 (-)Ensembl
GRCm38.p6 Ensembl870,650,178 - 70,659,651 (-)Ensembl
RefSeq Acc Id: NM_023217   ⟹   NP_075706
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,086 - 71,112,388 (-)NCBI
GRCm38870,646,436 - 70,659,738 (-)NCBI
MGSCv37873,173,010 - 73,183,580 (-)RGD
Celera873,203,198 - 73,216,496 (-)ENTREZGENE
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509719   ⟹   XP_006509782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,112,503 (-)NCBI
GRCm38870,646,437 - 70,659,855 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243718   ⟹   XP_030099578
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,112,496 (-)NCBI
GRCm38870,646,437 - 70,659,848 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243719   ⟹   XP_030099579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,113,096 (-)NCBI
GRCm38870,646,437 - 70,660,446 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243720   ⟹   XP_030099580
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,111,551 (-)NCBI
GRCm38870,646,437 - 70,658,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243721   ⟹   XP_030099581
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,112,326 (-)NCBI
GRCm38870,646,437 - 70,659,672 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243722   ⟹   XP_030099582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,099,087 - 71,113,067 (-)NCBI
GRCm38870,646,437 - 70,660,383 (-)NCBI
Sequence:
RefSeq Acc Id: NP_075706   ⟸   NM_023217
- UniProtKB: Q9ESW8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006509782   ⟸   XM_006509719
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030099579   ⟸   XM_030243719
- Peptide Label: isoform X2
- UniProtKB: A0A1B0GSC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030099582   ⟸   XM_030243722
- Peptide Label: isoform X2
- UniProtKB: A0A1B0GSC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030099578   ⟸   XM_030243718
- Peptide Label: isoform X2
- UniProtKB: A0A1B0GSC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030099581   ⟸   XM_030243721
- Peptide Label: isoform X2
- UniProtKB: A0A1B0GSC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030099580   ⟸   XM_030243720
- Peptide Label: isoform X2
- UniProtKB: A0A1B0GSC4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000070778   ⟸   ENSMUST00000070173
Ensembl Acc Id: ENSMUSP00000148119   ⟸   ENSMUST00000211715
Ensembl Acc Id: ENSMUSP00000148241   ⟸   ENSMUST00000210786
Ensembl Acc Id: ENSMUSP00000147879   ⟸   ENSMUST00000210307
Ensembl Acc Id: ENSMUSP00000148163   ⟸   ENSMUST00000210193
Ensembl Acc Id: ENSMUSP00000148141   ⟸   ENSMUST00000209768

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESW8-F1-model_v2 AlphaFold Q9ESW8 1-209 view protein structure

Promoters
RGD ID:8667331
Promoter ID:EPDNEW_M11697
Type:initiation region
Name:Pgpep1_1
Description:Mus musculus pyroglutamyl-peptidase I , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,659,681 - 70,659,741EPDNEW
RGD ID:6843603
Promoter ID:MM_KWN:54725
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_023217
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36873,183,446 - 73,184,122 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913772 AgrOrtholog
Ensembl Genes ENSMUSG00000056204 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070173 ENTREZGENE
  ENSMUST00000070173.9 UniProtKB/Swiss-Prot
  ENSMUST00000209768.2 UniProtKB/TrEMBL
  ENSMUST00000210193.2 UniProtKB/TrEMBL
  ENSMUST00000210307 ENTREZGENE
  ENSMUST00000210307.2 UniProtKB/TrEMBL
  ENSMUST00000210786.2 UniProtKB/TrEMBL
  ENSMUST00000211715.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Peptidase_C15 UniProtKB/Swiss-Prot
  Peptidase_C15-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C15-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGPEP1_Cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGPEP1_Glu_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66522 UniProtKB/Swiss-Prot
MGD MGI:1913772 ENTREZGENE
NCBI Gene 66522 ENTREZGENE
PANTHER PTHR23402 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23402:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_C15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pgpep1 PhenoGen
PIRSF Prld-crbxl_pptds UniProtKB/Swiss-Prot
PRINTS PYROGLUPTASE UniProtKB/Swiss-Prot
PROSITE PYRASE_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PYRASE_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53182 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GSC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GSY1_MOUSE UniProtKB/TrEMBL
  A0A1B0GT02_MOUSE UniProtKB/TrEMBL
  A0A1B0GT19_MOUSE UniProtKB/TrEMBL
  A0A1B0GT82_MOUSE UniProtKB/TrEMBL
  PGPI_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Pgpep1  pyroglutamyl-peptidase I  Gm19458  predicted gene, 19458  Data merged from RGD:5141524 737654 PROVISIONAL