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Gene: Ap1s1 (adaptor protein complex AP-1, sigma 1) Mus musculus
Symbol: Ap1s1
Name: adaptor protein complex AP-1, sigma 1
Description: Involved in retrograde transport, endosome to Golgi. Localizes to the terminal bouton. Human ortholog(s) of this gene implicated in MEDNIK syndrome. Orthologous to human AP1S1 (adaptor related protein complex 1 subunit sigma 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adapter-related protein complex 1 sigma-1A subunit; adapter-related protein complex 1 subunit sigma-1A; adaptor protein complex AP-1 sigma-1A subunit; adaptor protein complex AP-1 subunit sigma-1A; adaptor-related protein complex 1 subunit sigma-1A; adaptor-related protein complex AP-1, sigma 1; AP-1 complex subunit sigma-1A; AP19; clathrin assembly protein complex 1 sigma-1A small chain; clathrin coat assembly protein AP19; golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; sigma 1a subunit of AP-1 clathrin; sigma-adaptin 1A; sigma1A-adaptin
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm385137,034,993 - 137,046,108 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375137,510,864 - 137,521,930 (-)NCBIGRCm37mm9NCBIm37
MGSCv365137,319,621 - 137,330,687 (-)NCBImm8
Celera5134,051,733 - 134,062,892 (-)NCBICelera
Cytogenetic Map5 G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ap1s1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314227
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.