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Gene: Smarcb1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) Mus musculus
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Symbol: Smarcb1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Description: Predicted to have several functions, including RNA polymerase I CORE element sequence-specific DNA binding activity; Tat protein binding activity; and p53 binding activity. Involved in blastocyst hatching; cell differentiation; and negative regulation of cell population proliferation. Localizes to the chromosome. Used to study atypical teratoid rhabdoid tumor. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 3; atypical teratoid rhabdoid tumor; neurilemmomatosis; and rhabdoid cancer. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU020204; Baf47; BRG1-associated factor 47; Ini1; integrase interactor 1 protein; MGC132387; mSNF5; Snf5; SNF5 homolog; SNF5/INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381075,896,769 - 75,921,614 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,359,514 - 75,384,359 (-)NCBIGRCm37mm9NCBIm37
MGSCv361075,340,491 - 75,365,304 (-)NCBImm8
Celera1076,941,458 - 76,966,299 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Smarcb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318722
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.