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Gene: Smarcb1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) Mus musculus
Symbol: Smarcb1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Description: Predicted to have several functions, including RNA polymerase I CORE element sequence-specific DNA binding activity; Tat protein binding activity; and p53 binding activity. Involved in blastocyst hatching; cell differentiation; and negative regulation of cell population proliferation. Localizes to the chromosome. Used to study atypical teratoid rhabdoid tumor. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 3; atypical teratoid rhabdoid tumor; neurilemmomatosis; and rhabdoid cancer. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU020204; Baf47; BRG1-associated factor 47; Ini1; integrase interactor 1 protein; MGC132387; mSNF5; Snf5; SNF5 homolog; SNF5/INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381075,896,769 - 75,921,614 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,359,514 - 75,384,359 (-)NCBIGRCm37mm9NCBIm37
MGSCv361075,340,491 - 75,365,304 (-)NCBImm8
Celera1076,941,458 - 76,966,299 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Smarcb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318722
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.