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Gene: Bcl2 (B cell leukemia/lymphoma 2) Mus musculus
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Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Description: Exhibits protein heterodimerization activity; protein phosphatase 2A binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and negative regulation of programmed cell death. Localizes to several cellular components, including the mitochondrial membrane; myelin sheath; and nuclear membrane. Used to study oligomeganephronia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; and prostate cancer. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and sensory organ. Orthologous to human BCL2 (BCL2 apoptosis regulator).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apoptosis regulator Bcl-2; AW986256; B-cell leukemia/lymphoma 2; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
Orthologs:
Homo sapiens (human) : BCL2 (BCL2 apoptosis regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bcl2 (BCL2, apoptosis regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl2 (BCL2 apoptosis regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL2 (BCL2 apoptosis regulator)
Canis lupus familiaris (dog) : BCL2 (BCL2 apoptosis regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2 (BCL2 apoptosis regulator)
Sus scrofa (pig) : BCL2 (BCL2 apoptosis regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1106,538,178 - 106,714,274 (-)Ensembl
GRCm381106,538,176 - 106,714,290 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371108,434,756 - 108,610,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv361108,365,740 - 108,541,849 (-)NCBImm8
Celera1109,386,733 - 109,563,656 (-)NCBICelera
Cytogenetic Map1 E2.1NCBI
cM Map149.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model