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Gene: Xbp1 (X-box binding protein 1) Mus musculus
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Symbol: Xbp1
Name: X-box binding protein 1
Description: Exhibits several functions, including RNA polymerase II transcription factor binding activity; enzyme binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in several processes, including gland development; lipid homeostasis; and positive regulation of secretion. Localizes to the cytoplasm and nucleus. Used to study inflammatory bowel disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Orthologous to human XBP1 (X-box binding protein 1); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; forkhead class A signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (-)-anisomycin; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D11Ertd39e; tax-responsive element-binding protein 5 homolog; TREB-5; TREB5; X-box-binding protein 1; XBP-1
Orthologs:
Homo sapiens (human) : XBP1 (X-box binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Xbp1 (X-box binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xbp1 (X-box binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XBP1 (X-box binding protein 1)
Canis lupus familiaris (dog) : XBP1 (X-box binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xbp1 (X-box binding protein 1)
Sus scrofa (pig) : XBP1 (X-box binding protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38115,520,641 - 5,525,993 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37115,420,970 - 5,425,875 (+)NCBIGRCm37mm9NCBIm37
MGSCv36115,420,970 - 5,425,875 (+)NCBImm8
Celera116,013,628 - 6,018,986 (+)NCBICelera
Cytogenetic Map11 A1NCBI
cM Map113.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Xbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332312
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.