Loxl1 (lysyl oxidase-like 1) - Rat Genome Database

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Gene: Loxl1 (lysyl oxidase-like 1) Mus musculus
Analyze
Symbol: Loxl1
Name: lysyl oxidase-like 1
RGD ID: 1318706
MGI Page MGI
Description: Enables oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor. Predicted to be involved in collagen fibril organization and peptidyl-lysine oxidation. Located in extracellular matrix. Is expressed in several structures, including brain; genitourinary system; and liver. Used to study exfoliation syndrome. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; exfoliation syndrome; and primary open angle glaucoma. Orthologous to human LOXL1 (lysyl oxidase like 1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: L; Loxl; lysyl oxidase 2; lysyl oxidase homolog 1; lysyl oxidase-like protein 1; MGC106801
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39958,195,006 - 58,220,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl958,195,021 - 58,220,469 (-)EnsemblGRCm39 Ensembl
GRCm38958,287,723 - 58,313,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl958,287,738 - 58,313,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv37958,135,530 - 58,161,019 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36958,086,738 - 58,111,322 (-)NCBIMGSCv36mm8
Celera955,521,427 - 55,546,968 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
azoxystrobin  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
Benzo[ghi]perylene  (EXP)
Benzo[k]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbendazim  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP,ISO)
choline  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
cumene  (EXP)
Cuprizon  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diazinon  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (ISO)
L-methionine  (EXP)
leflunomide  (EXP)
microcystin-LR  (ISO)
monosodium L-glutamate  (EXP)
Muraglitazar  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
oxaliplatin  (ISO)
picoxystrobin  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
pyrimidifen  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
Trapidil  (ISO)
trimellitic anhydride  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas. Chakrabarti S, etal., Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2343-7. doi: 10.1167/iovs.07-1557. Epub 2008 Jan 25.
2. Atomic force microscopy-based antibody recognition imaging of proteins in the pathological deposits in pseudoexfoliation syndrome. Creasey R, etal., Ultramicroscopy. 2011 Jul;111(8):1055-61. doi: 10.1016/j.ultramic.2011.03.008. Epub 2011 Mar 21.
3. LOXL1 promoter haplotypes are associated with exfoliation syndrome in a U.S. Caucasian population. Fan BJ, etal., Invest Ophthalmol Vis Sci. 2011 Apr 12;52(5):2372-8. doi: 10.1167/iovs.10-6268. Print 2011 Apr.
4. Polymorphisms in ARMS2 (LOC387715) and LOXL1 genes in the Japanese with age-related macular degeneration. Fuse N, etal., Am J Ophthalmol. 2011 Mar;151(3):550-6.e1. doi: 10.1016/j.ajo.2010.08.048. Epub 2011 Jan 13.
5. Evaluation of LOXL1 polymorphisms in primary open-angle glaucoma in southern and northern Chinese. Gong WF, etal., Mol Vis. 2008;14:2381-9. Epub 2008 Dec 19.
6. Association of LOXL1 gene polymorphisms with exfoliation syndrome/glaucoma and primary open angle glaucoma in a Turkish population. Kasim B, etal., Mol Vis. 2013;19:114-20. Epub 2013 Jan 28.
7. Association of LOXL1 polymorphisms with pseudoexfoliation in the Chinese. Lee KY, etal., Mol Vis. 2009 Jun 4;15:1120-6.
8. The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma. Liu Y, etal., Mol Vis. 2012;18:2976-81. Epub 2012 Dec 14.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Role of Lysyl oxidase-like 1 gene polymorphisms in Pakistani patients with pseudoexfoliative glaucoma. Micheal S, etal., Mol Vis. 2012;18:1040-4. Epub 2012 Apr 25.
12. Comparison of gene expression profiling in pressure and volume overload-induced myocardial hypertrophies in rats. Miyazaki H, etal., Hypertens Res. 2006 Dec;29(12):1029-45.
13. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. TT polymorphism in rs2165241 and rs1048661 region in lysyl oxidase like-1 gene may have a role in stress urinary incontinence physiopathology. Ozbek E, etal., J Obstet Gynaecol Res. 2013 Jan;39(1):237-42. doi: 10.1111/j.1447-0756.2012.01942.x. Epub 2012 Jul 6.
16. An investigation into LOXL1 variants in black South African individuals with exfoliation syndrome. Rautenbach RM, etal., Arch Ophthalmol. 2011 Feb;129(2):206-10. doi: 10.1001/archophthalmol.2010.349.
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Lyst mutation in mice recapitulates iris defects of human exfoliation syndrome. Trantow CM, etal., Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1205-14. doi: 10.1167/iovs.08-2791. Epub 2008 Nov 21.
20. Lysyl oxidase-like 1 gene polymorphisms in German patients with normal tension glaucoma, pigmentary glaucoma and exfoliation glaucoma. Wolf C, etal., J Glaucoma. 2010 Feb;19(2):136-41. doi: 10.1097/IJG.0b013e31819f9330.
21. Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1. Yu HG, etal., Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2599-605. doi: 10.1167/iovs.07-1508. Epub 2008 Feb 22.
Additional References at PubMed
PMID:8617512   PMID:9119402   PMID:9250877   PMID:9585423   PMID:10022501   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11486040   PMID:11684696   PMID:12477932  
PMID:14610273   PMID:14745449   PMID:15482472   PMID:15489334   PMID:15609098   PMID:16141072   PMID:16141073   PMID:16157454   PMID:16251195   PMID:16436666   PMID:16707424   PMID:17916774  
PMID:17967808   PMID:18265927   PMID:18287559   PMID:18495804   PMID:18799693   PMID:19165826   PMID:19201700   PMID:19458888   PMID:21873635   PMID:21979435   PMID:22159717   PMID:22238283  
PMID:22763477   PMID:24006456   PMID:24194600   PMID:24425853   PMID:24952961   PMID:25988230   PMID:26538021   PMID:26816005   PMID:26954549   PMID:27626380   PMID:27645581   PMID:28071719  
PMID:28700664   PMID:29115860   PMID:29366776   PMID:29419647   PMID:30389913   PMID:30399364   PMID:30550785   PMID:30890638   PMID:31403161   PMID:31979322   PMID:32335309   PMID:32533648  
PMID:32623782   PMID:32682987   PMID:34014450   PMID:34569648  


Genomics

Comparative Map Data
Loxl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39958,195,006 - 58,220,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl958,195,021 - 58,220,469 (-)EnsemblGRCm39 Ensembl
GRCm38958,287,723 - 58,313,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl958,287,738 - 58,313,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv37958,135,530 - 58,161,019 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36958,086,738 - 58,111,322 (-)NCBIMGSCv36mm8
Celera955,521,427 - 55,546,968 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.65NCBI
LOXL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381573,926,462 - 73,952,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1573,925,989 - 73,952,137 (+)EnsemblGRCh38hg38GRCh38
GRCh371574,218,803 - 74,244,477 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,005,842 - 72,031,531 (+)NCBINCBI36Build 36hg18NCBI36
Build 341572,005,872 - 72,031,529NCBI
Celera1551,098,617 - 51,121,842 (+)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1551,050,475 - 51,076,334 (+)NCBIHuRef
CHM1_11574,336,766 - 74,362,440 (+)NCBICHM1_1
T2T-CHM13v2.01571,743,808 - 71,769,482 (+)NCBIT2T-CHM13v2.0
Loxl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2858,692,592 - 58,716,356 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl858,692,593 - 58,716,356 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx864,222,523 - 64,247,347 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0862,500,076 - 62,524,898 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0860,364,649 - 60,389,471 (-)NCBIRnor_WKY
Rnor_6.0863,067,757 - 63,092,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl863,067,300 - 63,092,009 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,843,790 - 62,868,157 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,083,052 - 62,106,827 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1862,102,104 - 62,125,881 (-)NCBI
Celera858,155,183 - 58,178,908 (-)NCBICelera
Cytogenetic Map8q24NCBI
Loxl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,715,421 - 3,735,219 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,715,109 - 3,734,641 (-)NCBIChiLan1.0ChiLan1.0
LOXL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11571,592,037 - 71,616,540 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01552,835,675 - 52,861,324 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOXL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,191,201 - 37,204,163 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,183,128 - 37,204,058 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,115,569 - 37,136,800 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03037,387,023 - 37,408,267 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3037,388,729 - 37,410,953 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13037,338,990 - 37,360,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03037,365,837 - 37,385,844 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03037,622,173 - 37,642,217 (+)NCBIUU_Cfam_GSD_1.0
Loxl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,227,470 - 115,251,814 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,075,461 - 33,099,910 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647133,075,542 - 33,099,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOXL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl759,481,412 - 59,505,149 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1759,481,410 - 59,505,161 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2764,103,016 - 64,126,771 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOXL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1269,539,383 - 9,565,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl269,538,758 - 9,564,751 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048132,049,338 - 132,075,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Loxl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624781520,143 - 537,727 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624781518,703 - 537,657 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:452
Count of miRNA genes:326
Interacting mature miRNAs:355
Transcripts:ENSMUST00000061799
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
1301287Feml2_mfemur length in high growth mice 2 (mouse)Not determined95750728363207282Mouse
1301965Vmbic5_mventral midbrain iron content 5 (mouse)Not determined95759149265831177Mouse
1301549Bbaa9_mB.burgdorferi-associated arthritis 9 (mouse)Not determined95780504771481754Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95780504786121973Mouse

Markers in Region
Loxl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9BUniSTS
cM Map933.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061799   ⟹   ENSMUSP00000057406
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl958,195,021 - 58,220,469 (-)Ensembl
GRCm38.p6 Ensembl958,287,738 - 58,313,186 (-)Ensembl
RefSeq Acc Id: NM_010729   ⟹   NP_034859
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39958,195,006 - 58,220,495 (-)NCBI
GRCm38958,287,723 - 58,313,212 (-)ENTREZGENE
MGSCv37958,135,530 - 58,161,019 (-)RGD
Celera955,521,427 - 55,546,968 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034859   ⟸   NM_010729
- Peptide Label: preproprotein
- UniProtKB: P97873 (UniProtKB/Swiss-Prot),   A0A0R4J0Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000057406   ⟸   ENSMUST00000061799

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97873-F1-model_v2 AlphaFold P97873 1-607 view protein structure

Promoters
RGD ID:6844751
Promoter ID:MM_KWN:57586
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000064417,   NM_010729
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36958,159,576 - 58,160,962 (-)MPROMDB
RGD ID:8669810
Promoter ID:EPDNEW_M12935
Type:initiation region
Name:Loxl1_2
Description:Mus musculus lysyl oxidase-like 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12936  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38958,312,967 - 58,313,027EPDNEW
RGD ID:8669812
Promoter ID:EPDNEW_M12936
Type:initiation region
Name:Loxl1_1
Description:Mus musculus lysyl oxidase-like 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12935  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38958,313,197 - 58,313,257EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106096 AgrOrtholog
Ensembl Genes ENSMUSG00000032334 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000057406 ENTREZGENE
  ENSMUSP00000057406.9 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000061799 ENTREZGENE
  ENSMUST00000061799.10 UniProtKB/TrEMBL
InterPro Lysyl_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lysyl_oxidase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16949 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:106096 ENTREZGENE
NCBI Gene 16949 ENTREZGENE
Pfam Lysyl_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Loxl1 PhenoGen
PRINTS LYSYLOXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LYSYL_OXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0Q4 ENTREZGENE, UniProtKB/TrEMBL
  LOXL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q4QQJ7_MOUSE UniProtKB/TrEMBL
  Q8BP04_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q91ZY4 UniProtKB/Swiss-Prot
  Q99KX3 UniProtKB/Swiss-Prot