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Gene: Plk1 (polo like kinase 1) Mus musculus
Symbol: Plk1
Name: polo like kinase 1
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including meiotic chromosome segregation; peptidyl-serine phosphorylation; and synaptonemal complex disassembly. Localizes to the chromosome and microtubule organizing center. Predicted to colocalize with the spindle microtubule. Human ortholog(s) of this gene implicated in urinary bladder cancer. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human PLK1 (polo like kinase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Plk; PLK-1; polo-like kinase 1; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13
Homo sapiens (human) : PLK1 (polo like kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plk1 (polo-like kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plk1 (polo like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK1 (polo like kinase 1)
Canis lupus familiaris (dog) : PLK1 (polo like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk1 (polo like kinase 1)
Sus scrofa (pig) : PLK1 (polo like kinase 1)
more info ...
Related Pseudogenes: Gm18552   Plk-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7122,159,439 - 122,169,873 (+)Ensembl
GRCm387122,159,435 - 122,169,884 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377129,302,951 - 129,313,389 (+)NCBIGRCm37mm9NCBIm37
MGSCv367121,950,641 - 121,961,011 (+)NCBImm8
Celera7122,049,692 - 122,060,205 (+)NCBICelera
Cytogenetic Map7 F2NCBI
cM Map765.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Plk1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11121
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.