Atf6 (activating transcription factor 6) - Rat Genome Database
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Gene: Atf6 (activating transcription factor 6) Mus musculus
Analyze
Symbol: Atf6
Name: activating transcription factor 6
RGD ID: 1313518
MGI Page MGI
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein heterodimerization activity; and ubiquitin protein ligase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in several structures, including embryo mesenchyme; eye; liver; long bone; and tooth. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Alzheimer's disease pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-lipoic acid; 1,2-dimethylhydrazine; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9130025P16Rik; 9630036G24; AA789574; activating transcription factor 6 alpha; ATF6-alpha; Atf6alpha; cAMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 alpha; ESTM4; ESTM49
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,532,026 - 170,696,414 (-)NCBIGRCm39mm39
GRCm39 Ensembl1170,532,243 - 170,695,340 (-)Ensembl
GRCm381170,704,457 - 170,868,585 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,704,674 - 170,867,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,634,588 - 172,797,902 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,541,132 - 172,710,564 (-)NCBImm8
Celera1173,146,825 - 173,324,073 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (ISO)
(R)-lipoic acid  (EXP)
(S)-nicotine  (ISO)
1,10-phenanthroline  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
15-acetyldeoxynivalenol  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dichlorophenol  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-acetyldeoxynivalenol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxynon-2-enal  (ISO)
4-phenylbutyric acid  (EXP,ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (EXP)
antirheumatic drug  (ISO)
apigenin  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atazanavir sulfate  (ISO)
BAPTA  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP,ISO)
bilirubin IXalpha  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
boric acid  (ISO)
brefeldin A  (EXP)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cantharidin  (ISO)
casticin  (ISO)
chenodeoxycholic acid  (ISO)
chloroacetic acid  (EXP)
chromium(6+)  (ISO)
chrysazin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
D-penicillamine  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
demethoxycurcumin  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (EXP,ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
dioscin  (EXP,ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
fisetin  (ISO)
furan  (ISO)
Fusarenone X  (ISO)
gadolinium trichloride  (ISO)
geraniol  (ISO)
ginsenoside Rg1  (ISO)
glucose  (ISO)
glutathione  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
Guanabenz  (EXP)
GW 4064  (EXP)
hexadecanoic acid  (ISO)
indometacin  (ISO)
ivermectin  (EXP)
lead diacetate  (EXP,ISO)
lipoic acid  (EXP)
lipopolysaccharide  (ISO)
luteolin  (ISO)
LY294002  (EXP,ISO)
lycopene  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melatonin  (ISO)
menadione  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (EXP)
methylseleninic acid  (ISO)
metyrapone  (ISO)
minocycline  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-hexadecanoylsphingosine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
naltrexone  (ISO)
nefazodone  (ISO)
nelfinavir  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nilotinib  (ISO)
Nivalenol  (ISO)
Nonidet P-40  (ISO)
Norbinaltorphimine  (ISO)
ochratoxin A  (ISO)
oleic acid  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
phenethyl caffeate  (EXP)
poly(guanylic acid)  (ISO)
potassium dichromate  (EXP,ISO)
propiconazole  (EXP)
pyocyanine  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
Riluzole  (ISO)
rimonabant  (ISO)
rotenone  (ISO)
salubrinal  (EXP)
saquinavir  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP,ISO)
SR 144528  (ISO)
streptozocin  (ISO)
tacrolimus hydrate  (EXP)
tauroursodeoxycholic acid  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
thymoquinone  (ISO)
Tiron  (EXP)
titanium dioxide  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
triclocarban  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (EXP)
tungsten  (EXP)
tunicamycin  (EXP,ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14559994   PMID:14610273   PMID:14681479   PMID:15238534  
PMID:15598891   PMID:15618518   PMID:15897261   PMID:16141072   PMID:16141073   PMID:16452489   PMID:17090218   PMID:17765676   PMID:17765679   PMID:17765680   PMID:17913437   PMID:17967808  
PMID:18319259   PMID:18360008   PMID:18650380   PMID:18799693   PMID:19139267   PMID:19202076   PMID:19543265   PMID:19615339   PMID:19633360   PMID:19805353   PMID:19858219   PMID:19940266  
PMID:20348923   PMID:20631254   PMID:21044701   PMID:21131360   PMID:21150130   PMID:21267068   PMID:21284983   PMID:21385877   PMID:21841196   PMID:21873635   PMID:21917591   PMID:22013072  
PMID:22102412   PMID:22124452   PMID:22189555   PMID:22326432   PMID:22386934   PMID:22431749   PMID:22555069   PMID:22643896   PMID:22682248   PMID:22699507   PMID:23042294   PMID:23112876  
PMID:23221566   PMID:23395094   PMID:23611781   PMID:23618865   PMID:23618905   PMID:23724040   PMID:24035931   PMID:24225943   PMID:24275136   PMID:24339898   PMID:24475193   PMID:24519940  
PMID:24726366   PMID:24746698   PMID:25035425   PMID:25135476   PMID:25203138   PMID:25332179   PMID:25351847   PMID:25492867   PMID:25725420   PMID:25754093   PMID:26029869   PMID:26105053  
PMID:26106220   PMID:26374329   PMID:26527399   PMID:26674075   PMID:26708632   PMID:26724566   PMID:26752648   PMID:26816051   PMID:26842780   PMID:27207533   PMID:27217380   PMID:27239042  
PMID:27333444   PMID:27416896   PMID:27581066   PMID:27717400   PMID:27932512   PMID:27938665   PMID:28100484   PMID:28237965   PMID:28396396   PMID:28433684   PMID:28535855   PMID:28564599  
PMID:28747345   PMID:28958904   PMID:29436030   PMID:29522813   PMID:29523177   PMID:29666470   PMID:29773650   PMID:30236984   PMID:30504459   PMID:30582446   PMID:30604742   PMID:30635284  
PMID:30639234   PMID:30643122   PMID:30685387   PMID:30765833   PMID:30963569   PMID:31255486   PMID:31320508   PMID:31689600   PMID:31781038   PMID:32005751   PMID:32053121   PMID:32085622  
PMID:32313051   PMID:32325033   PMID:32758541   PMID:32788214  


Genomics

Comparative Map Data
Atf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,532,026 - 170,696,414 (-)NCBIGRCm39mm39
GRCm39 Ensembl1170,532,243 - 170,695,340 (-)Ensembl
GRCm381170,704,457 - 170,868,585 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,704,674 - 170,867,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,634,588 - 172,797,902 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,541,132 - 172,710,564 (-)NCBImm8
Celera1173,146,825 - 173,324,073 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.96NCBI
ATF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1161,766,298 - 161,977,574 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1161,766,320 - 161,964,070 (+)EnsemblGRCh38hg38GRCh38
GRCh381161,766,320 - 161,964,070 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,736,110 - 161,933,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,002,708 - 160,195,476 (+)NCBINCBI36hg18NCBI36
Build 341158,467,741 - 158,660,510NCBI
Celera1134,839,502 - 135,032,269 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,980,970 - 133,178,653 (+)NCBIHuRef
CHM1_11163,157,827 - 163,355,630 (+)NCBICHM1_1
Atf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21382,927,579 - 83,106,381 (-)NCBI
Rnor_6.0 Ensembl1389,055,983 - 89,242,443 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01389,053,457 - 89,242,531 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01393,668,054 - 93,854,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,543,773 - 86,718,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11386,559,136 - 86,734,174 (-)NCBI
Celera1382,588,612 - 82,760,829 (-)NCBICelera
Cytogenetic Map13q24NCBI
Atf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546214,357,945 - 14,548,543 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546214,352,956 - 14,553,299 (-)NCBIChiLan1.0ChiLan1.0
ATF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11140,977,750 - 141,181,837 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,977,750 - 141,176,725 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01137,178,629 - 137,382,256 (+)NCBIMhudiblu_PPA_v0panPan3
ATF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13820,705,167 - 20,903,852 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3820,709,038 - 20,903,814 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3820,758,598 - 20,956,710 (-)NCBI
ROS_Cfam_1.03820,788,925 - 20,987,730 (-)NCBI
UMICH_Zoey_3.13820,761,253 - 20,959,710 (-)NCBI
UNSW_CanFamBas_1.03821,114,892 - 21,313,427 (-)NCBI
UU_Cfam_GSD_1.03821,406,602 - 21,593,774 (-)NCBI
Atf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,651,241 - 7,833,831 (+)NCBI
SpeTri2.0NW_004937131170,649 - 183,942 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl488,591,280 - 88,818,372 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1488,591,279 - 88,806,156 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2496,614,364 - 96,821,004 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATF6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,112,819 - 2,304,063 (-)NCBI
ChlSab1.1 Ensembl202,117,982 - 2,304,027 (-)Ensembl
Atf6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624826189,899 - 412,540 (+)NCBI

Position Markers
AW061147  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,850,648 - 170,850,758UniSTSGRCm38
MGSCv371172,780,779 - 172,780,889UniSTSGRCm37
Celera1173,305,652 - 173,305,762UniSTS
Cytogenetic Map1H3UniSTS
cM Map185.0UniSTS
Whitehead/MRC_RH12123.31UniSTS
Atf6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H3UniSTS
cM Map185.0UniSTS
D1Mit270  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,848,421 - 170,848,536UniSTSGRCm38
MGSCv371172,778,552 - 172,778,667UniSTSGRCm37
Celera1173,303,433 - 173,303,530UniSTS
Cytogenetic Map1H3UniSTS
cM Map192.3UniSTS
Whitehead Genetic191.8UniSTS
Whitehead/MRC_RH12123.41UniSTS
Whitehead_YAC1 UniSTS
AI326426  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,754,242 - 170,754,427UniSTSGRCm38
MGSCv371172,684,373 - 172,684,558UniSTSGRCm37
Celera1173,199,106 - 173,199,291UniSTS
Cytogenetic Map1H3UniSTS
cM Map185.0UniSTS
Whitehead/MRC_RH12125.32UniSTS
AA789574  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,709,845 - 170,710,050UniSTSGRCm38
MGSCv371172,639,976 - 172,640,181UniSTSGRCm37
Celera1173,152,212 - 173,152,417UniSTS
Cytogenetic Map1H3UniSTS
cM MapUN UniSTS
cM Map1 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1357854Sle16_msystematic lupus erythematosus susceptibility 16 (mouse)Not determined1169211172177550021Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170647303195471971Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164315658190802075Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1302037Nktcn1_mnatural killer T cell numbers 1 (mouse)Not determined1168358674171804689Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167929168189571420Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13207571Tcq11_mtotal cholesterol QTL 11 (mouse)1169310000179820000Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167758517191493284Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
10412205Bbaa30_mB.burgdorferi-associated arthritis 30 (mouse)Not determined1169211172174628870Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
4142065Bmd5b_mbone mineral density 5b (mouse)Not determined169007542171938066Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1673
Count of miRNA genes:705
Interacting mature miRNAs:878
Transcripts:ENSMUST00000027974, ENSMUST00000182787
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000027974   ⟹   ENSMUSP00000027974
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,704,674 - 170,867,771 (-)Ensembl
RefSeq Acc Id: ENSMUST00000182787
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,792,287 - 170,794,371 (-)Ensembl
RefSeq Acc Id: NM_001081304   ⟹   NP_001074773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,532,026 - 170,695,340 (-)NCBI
GRCm381170,704,457 - 170,867,771 (-)NCBI
MGSCv371172,634,588 - 172,797,902 (-)RGD
Celera1173,146,825 - 173,324,073 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496792   ⟹   XP_006496855
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,532,323 - 170,685,112 (-)NCBI
GRCm381170,704,754 - 170,857,744 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011238796   ⟹   XP_011237098
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,532,245 - 170,696,154 (-)NCBI
GRCm381170,704,754 - 170,868,585 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253420   ⟹   XP_030109280
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,532,245 - 170,696,414 (-)NCBI
GRCm381170,704,676 - 170,868,585 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001074773   ⟸   NM_001081304
- UniProtKB: F6VAN0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006496855   ⟸   XM_006496792
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011237098   ⟸   XM_011238796
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030109280   ⟸   XM_030253420
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000027974   ⟸   ENSMUST00000027974
Protein Domains
bZIP

Promoters
RGD ID:6875632
Promoter ID:EPDNEW_M1267
Type:initiation region
Name:Atf6_1
Description:Mus musculus activating transcription factor 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381170,867,768 - 170,867,828EPDNEW
RGD ID:6817385
Promoter ID:MM_KWN:2804
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Lung,   MEF_B4,   Spleen
Transcripts:NM_001081304
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361172,797,624 - 172,798,124 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1926157 AgrOrtholog
Ensembl Genes ENSMUSG00000026663 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000027974 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027974 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro ATF6A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:226641 UniProtKB/Swiss-Prot
MGD MGI:1926157 ENTREZGENE
NCBI Gene 226641 ENTREZGENE
PANTHER PTHR46164:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atf6 PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ATF6A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q811K9_MOUSE UniProtKB/TrEMBL
UniProt Secondary B2RU98 UniProtKB/Swiss-Prot
  Q8BZ84 UniProtKB/Swiss-Prot