Serpine1 (serine (or cysteine) peptidase inhibitor, clade E, member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Serpine1 (serine (or cysteine) peptidase inhibitor, clade E, member 1) Mus musculus
Analyze
Symbol: Serpine1
Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
RGD ID: 11055
MGI Page MGI
Description: Enables serine-type endopeptidase inhibitor activity. Involved in defense response to Gram-negative bacterium; negative regulation of plasminogen activation; and regulation of angiogenesis. Acts upstream of or within several processes, including cellular response to transforming growth factor beta stimulus; placenta development; and regulation of angiogenesis. Located in extracellular space. Is expressed in several structures, including aorta; extraembryonic component; liver; oocyte; and placenta. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); diabetic retinopathy (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human SERPINE1 (serpin family E member 1); PARTICIPATES IN fibrinolysis pathway; hypoxia inducible factor pathway; oxygen homeostasis pathway; INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; P; PA; PAI; PAI-1; PAI1; Pl; Planh1; plasminogen activator inhibitor 1; plasminogen activator inhibitor, type I; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); serine (or cysteine) proteinase inhibitor, clade E, member 1; serpin E1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,090,358 - 137,101,126 (-)NCBIGRCm39mm39
GRCm39 Ensembl5137,090,358 - 137,101,122 (-)Ensembl
GRCm385137,061,504 - 137,072,272 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,061,504 - 137,072,268 (-)EnsemblGRCm38mm10GRCm38
MGSCv375137,537,374 - 137,548,142 (-)NCBIGRCm37mm9NCBIm37
MGSCv365137,346,135 - 137,356,886 (-)NCBImm8
Celera5134,078,340 - 134,089,224 (-)NCBICelera
Cytogenetic Map5G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acquired Protein C Deficiency  (ISO)
Acute Lung Injury  (ISO)
acute necrotizing pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
Aggressive Fibromatosis  (ISO)
Albuminuria  (ISO)
Alcoholic Fatty Liver  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic rhinitis  (IEP)
amyloidosis  (ISO)
Animal Disease Models  (ISO)
anterolateral myocardial infarction  (IEP,IMP)
aortic aneurysm  (ISO)
Aortic Remodeling  (ISO)
Arterial Thrombosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
autistic disorder  (ISO)
bacterial pneumonia  (IMP)
Banti's Syndrome  (ISO)
Behcet's disease  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Bronchopulmonary Dysplasia  (ISO)
Cardiac Fibrosis  (ISO)
Carotid Artery Injuries  (ISO)
Central Serous Chorioretinopathy  (ISO)
cerebral infarction  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholestasis  (ISO)
Choroidal Neovascularization, Experimental  (IEP,IMP,ISO)
Chronic Allograft Nephropathy  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Relapsing Experimental Autoimmune Encephalomyelitis  (IMP)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Coronavirus infectious disease  (IEA)
Dermal Fibrosis  (IMP)
diabetes mellitus  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
disseminated intravascular coagulation  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Experimental Autoimmune Encephalomyelitis  (IEP)
Experimental Diabetes Mellitus  (IEP,ISO)
familial combined hyperlipidemia  (ISO)
familial hypercholesterolemia  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Fetal Growth Retardation  (ISO)
Fever  (ISO)
fibrosarcoma  (IMP)
focal segmental glomerulosclerosis  (ISO)
glaucoma  (ISO)
glomerulonephritis  (ISO)
glomerulosclerosis  (ISO)
Graft vs Host Disease  (IMP)
Graves Ophthalmopathy  (ISO)
Graves' disease  (ISO)
head and neck squamous cell carcinoma  (ISO)
hematopoietic system disease  (ISO)
Hemorrhage  (ISO)
hemorrhagic disease  (ISO)
high grade glioma  (ISO)
Hyaline Membrane Disease  (IMP)
hypertension  (ISO)
hyperthyroidism  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
Insulin Resistance  (ISO)
interstitial lung disease  (ISO)
Intestinal Polyps  (IMP)
Intestinal Reperfusion Injury  (ISO)
ischemic colitis  (ISO)
limited scleroderma  (IEP)
liver cirrhosis  (ISO)
liver disease  (ISO)
Liver Neoplasms  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
Lung Reperfusion Injury  (ISO)
macular degeneration  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
Multiple Organ Failure  (ISO)
Multiple Trauma  (ISO)
muscular atrophy  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neointima  (ISO)
Neovascularization, Pathologic  (ISO)
nephrotic syndrome  (ISO)
nervous system disease  (ISO)
neurilemmoma  (ISO)
non-alcoholic fatty liver disease  (ISO)
Noonan syndrome  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
oral squamous cell carcinoma  (ISO)
Oxygen-Induced Retinopathy  (IEP,IMP,ISO)
peripheral artery disease  (ISO)
Peritoneal Adhesions  (ISO)
Peritoneal Fibrosis  (ISO)
placental insufficiency  (ISO)
Plasminogen Activator Inhibitor-1 Deficiency  (ISO)
platelet-type bleeding disorder 10  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
pleurisy  (ISO)
pneumonia  (ISO)
polycystic ovary syndrome  (ISO)
polycythemia  (ISO)
polyneuropathy  (ISO)
portal vein thrombosis  (ISO)
Postoperative Atrial Fibrillation  (ISO)
pre-eclampsia  (ISO)
Pregnancy Complications  (ISO)
proliferative diabetic retinopathy  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
Radiation Nephropathy  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
renal fibrosis  (ISO)
respiratory allergy  (ISO)
retinal vein occlusion  (ISO)
retinopathy of prematurity  (ISO)
rhinitis  (ISO)
Rhinosinusitis  (ISO)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
sleep apnea  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Sudden Hearing Loss  (ISO)
systemic scleroderma  (ISO)
thoracic aortic aneurysm  (ISO)
thrombosis  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
uveal melanoma  (ISO)
Vascular Depression  (ISO)
Vascular Remodeling  (IDA)
Venous Thromboembolism  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
Wounds, Penetrating  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(R)-adrenaline  (EXP)
(R)-noradrenaline  (EXP)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (EXP)
1,10-phenanthroline  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2,4-dichlorophenol  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-butoxyethanol  (EXP)
2-chloroethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
4'-Methoxychalcone  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-aminophenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acrolein  (EXP)
adenine  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
aldosterone  (ISO)
all-trans-retinoic acid  (EXP)
aminoguanidine  (ISO)
ammonium chloride  (ISO)
amphibole asbestos  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimonite  (ISO)
apocynin  (ISO)
arecoline  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
aspalathin  (ISO)
atazanavir sulfate  (ISO)
atorvastatin calcium  (ISO)
atrazine  (ISO)
Aurin  (ISO)
azathioprine  (ISO)
barium chloride  (ISO)
benazepril  (EXP,ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bezafibrate  (EXP,ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
bortezomib  (ISO)
busulfan  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
butyric acid  (ISO)
C.I. Natural Red 20  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
calciol  (EXP)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
camostat  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chloroform  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
chlorpyrifos  (EXP)
choline  (EXP,ISO)
chrysene  (EXP)
ciglitazone  (ISO)
cis-caffeic acid  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
Clofop  (ISO)
clothianidin  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (EXP)
curcumin  (ISO)
cyanocob(III)alamin  (ISO)
cycloheximide  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (EXP,ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzofuran  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP,ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
dienogest  (ISO)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dinitrogen  (ISO)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
efavirenz  (ISO)
emodin  (ISO)
enalapril  (ISO)
enalaprilat dihydrate  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
eplerenone  (ISO)
eprosartan  (ISO)
Ethyl icosapentate  (ISO)
ethyl methanesulfonate  (ISO)
famotidine  (ISO)
fenofibrate  (EXP,ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fosinopril  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
geldanamycin  (ISO)
gemfibrozil  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
gestodene  (ISO)
glucose  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
Goe 6976  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphite  (ISO)
guanethidine  (EXP)
GW 501516  (ISO)
heparin  (ISO)
hexadecanoic acid  (ISO)
Hexadimethrine bromide  (ISO)
Honokiol  (ISO)
hydralazine  (ISO)
hydrochlorothiazide  (ISO)
hydrogen chloride  (EXP)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (EXP)
hydroxychloroquine  (ISO)
hydroxyl  (ISO)
hypochlorous acid  (EXP)
indirubin-3'-monoxime  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
iron(III) citrate  (ISO)
isobutanol  (ISO)
isoprenaline  (ISO)
isorhamnetin  (EXP,ISO)
isotretinoin  (ISO)
ivermectin  (EXP)
kainic acid  (EXP)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lactacystin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
linoleic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
LY 364947  (EXP)
magnesium atom  (ISO)
magnesium dichloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (ISO)
Mecamylamine  (EXP)
medroxyprogesterone acetate  (ISO)
meglumine amidotrizoate  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
metaproterenol  (ISO)
metformin  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methyl beta-cyclodextrin  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mifepristone  (ISO)
mitomycin C  (ISO)
mitoxantrone  (ISO)
monocrotaline  (EXP)
N-acetylsphingosine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP)
niclosamide  (EXP)
nicotine  (ISO)
nicotinic acid  (ISO)
nonanedioic acid  (ISO)
Nonidet P-40  (ISO)
norethisterone  (ISO)
notoginsenoside R1  (EXP,ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
octadecanoic acid  (EXP)
oleic acid  (ISO)
Olmesartan medoxomil  (ISO)
orciprenaline  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
paricalcitol  (ISO)
pentane-2,3-dione  (ISO)
Pentoxifylline  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
Phenelzine  (EXP)
phenethyl isothiocyanate  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phentolamine  (EXP)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosgene  (EXP)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pioglitazone  (ISO)
pirfenidone  (ISO)
pirinixic acid  (EXP,ISO)
poly(I:C)  (ISO)
potassium chloride  (ISO)
potassium dichromate  (ISO)
procyanidin B3  (EXP)
progesterone  (ISO)
propanal  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ranitidine  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (EXP,ISO)
rimonabant  (ISO)
rosmarinic acid  (EXP,ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
saralasin  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
Securinine  (ISO)
serpentine asbestos  (EXP)
Shikonin  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
spironolactone  (ISO)
streptozocin  (EXP,ISO)
succimer  (EXP)
sulforaphane  (EXP)
sulindac sulfide  (ISO)
sunitinib  (ISO)
superoxide  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
taurocholic acid  (EXP)
telmisartan  (EXP,ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thiacloprid  (EXP)
thimerosal  (ISO)
thioacetamide  (ISO)
thiophanate-methyl  (EXP)
tibolone  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trans-caffeic acid  (EXP)
triadimefon  (ISO)
triamterene  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
undecane  (ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
wortmannin  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc molecular entity  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)
ziram  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (ISO)
cellular response to aldosterone  (ISO)
cellular response to angiotensin  (ISO)
cellular response to ATP  (ISO)
cellular response to cAMP  (ISO)
cellular response to cGMP  (ISO)
cellular response to cycloheximide  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
cellular response to glucagon stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to gravity  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to leukemia inhibitory factor  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to metal ion  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to nicotine  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to potassium ion  (ISO)
cellular response to resveratrol  (ISO)
cellular response to transforming growth factor beta stimulus  (IDA,ISO)
cellular response to xenobiotic stimulus  (ISO)
decidualization  (ISO)
defense response to Gram-negative bacterium  (IMP,ISO)
dentinogenesis  (ISO)
female gonad development  (ISO)
glucose homeostasis  (ISO)
mast cell activation  (ISO)
negative regulation of cell adhesion mediated by integrin  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of endopeptidase activity  (IBA,ISO)
negative regulation of endothelial cell apoptotic process  (ISO)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
negative regulation of fibrinolysis  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of peptidase activity  (IEA)
negative regulation of plasminogen activation  (IBA,IMP,ISO)
negative regulation of smooth muscle cell migration  (ISO)
negative regulation of smooth muscle cell-matrix adhesion  (ISO)
negative regulation of vascular wound healing  (IBA,IMP,ISO)
placenta development  (IMP)
positive regulation of angiogenesis  (IMP,ISO)
positive regulation of blood coagulation  (ISO)
positive regulation of calcium ion import  (ISO)
positive regulation of coagulation  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of epithelium regeneration  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of keratinocyte migration  (ISO)
positive regulation of leukotriene production involved in inflammatory response  (ISO)
positive regulation of monocyte chemotaxis  (ISO)
positive regulation of odontoblast differentiation  (ISO)
positive regulation of receptor-mediated endocytosis  (ISO)
regulation of angiogenesis  (IDA)
regulation of cell population proliferation  (IGI)
regulation of signaling receptor activity  (ISO)
replicative senescence  (ISO)
response to cytokine  (ISO)
response to epidermal growth factor  (ISO)
response to estrogen  (ISO)
response to hyperoxia  (ISO)
response to laminar fluid shear stress  (ISO)
response to lipopolysaccharide  (ISO)
response to nutrient levels  (ISO)
response to reactive oxygen species  (ISO)
response to starvation  (ISO)
response to transforming growth factor beta  (ISO)
tissue regeneration  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acute inflammation  (IAGP)
abnormal blood circulation  (IAGP)
abnormal body weight  (IAGP)
abnormal energy expenditure  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal interleukin level  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal sternum morphology  (IEA)
abnormal tumor necrosis factor level  (IAGP)
albuminuria  (IAGP)
atherosclerotic lesions  (IAGP)
cardiac fibrosis  (IAGP)
decreased angiogenesis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating interleukin-6 level  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased susceptibility to endotoxin shock  (IAGP)
decreased triglyceride level  (IAGP)
enhanced wound healing  (IAGP)
enlarged lymph nodes  (IEA)
glomerular crescent  (IAGP)
glomerulonephritis  (IAGP)
heart inflammation  (IAGP)
hyperglycemia  (IAGP)
impaired glucose tolerance  (IAGP)
increased acute inflammation  (IAGP)
increased angiogenesis  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased body temperature  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating insulin level  (IAGP)
increased granulocyte number  (IAGP)
increased oxygen consumption  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to Coronaviridae infection  (IAGP)
increased susceptibility to Coronaviridae infection induced morbidity/mortality  (IAGP)
increased urine protein level  (IAGP)
liver fibrosis  (IAGP)
lung hemorrhage  (IAGP)
obese  (IAGP)
premature death  (IAGP)
respiratory system inflammation  (IAGP)
weight loss  (IAGP)
References

References - curated
1. Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21.
2. Allaire E, etal., Circulation. 1998 Jul 21;98(3):249-55.
3. Asakura H, etal., J Thromb Haemost. 2005 May;3(5):1050-5.
4. Ashitani J, etal., Intern Med. 2002 Mar;41(3):181-5.
5. Askari AT, etal., J Exp Med. 2003 Mar 3;197(5):615-24.
6. Atta H, etal., Int J Surg. 2016 Feb;26:58-63. doi: 10.1016/j.ijsu.2015.12.065. Epub 2016 Jan 12.
7. Avendano MS, etal., Br J Pharmacol. 2016 May;173(9):1541-55. doi: 10.1111/bph.13457. Epub 2016 Mar 21.
8. Bansal DD, etal., J Mol Cell Cardiol. 1997 Nov;29(11):3105-14.
9. Barazzone C, etal., J Clin Invest. 1996 Dec 15;98(12):2666-73.
10. Basu A, etal., Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4974-81. doi: 10.1167/iovs.09-3619. Epub 2009 May 14.
11. Bayan K, etal., J Thromb Thrombolysis. 2009 Jul;28(1):57-62. doi: 10.1007/s11239-008-0244-8. Epub 2008 Aug 7.
12. Bonyadi M, etal., Eur J Pediatr. 2013 Jan;172(1):91-8. doi: 10.1007/s00431-012-1844-z. Epub 2012 Oct 5.
13. Boullu-Ciocca S, etal., Endocrine. 2015 Dec;50(3):608-19. doi: 10.1007/s12020-015-0657-z. Epub 2015 Jun 18.
14. Brims FJ, etal., Thorax. 2009 Dec;64(12):1037-43. Epub 2009 Aug 23.
15. Buczko W, etal., Pharmacol Ther. 1997 Oct-Dec;76(1-3):161-75.
16. Bulut EC, etal., Exp Physiol. 2016 Mar 9. doi: 10.1113/EP085708.
17. Castro MC, etal., Life Sci. 2015 Sep 15;137:1-6. doi: 10.1016/j.lfs.2015.07.010. Epub 2015 Jul 17.
18. Chang ML, etal., J Gastroenterol Hepatol. 2015 Feb;30(2):329-36. doi: 10.1111/jgh.12705.
19. Chang W, etal., J Biol Chem. 2010 Mar 12;285(11):8196-206. Epub 2010 Jan 8.
20. Charakida M, etal., Atherosclerosis. 2009 Jun;204(2):532-7. doi: 10.1016/j.atherosclerosis.2008.09.025. Epub 2008 Oct 5.
21. Chen SC, etal., J Urol. 2009 Jan;181(1):336-42. Epub 2008 Nov 17.
22. Chen Y, etal., Thromb Res. 2015 Jul;136(1):131-8. doi: 10.1016/j.thromres.2015.04.018. Epub 2015 Apr 22.
23. Cho SH, etal., BMC Ear Nose Throat Disord. 2012 Jun 6;12:5. doi: 10.1186/1472-6815-12-5.
24. Cosan D, etal., Genet Test Mol Biomarkers. 2009 Aug;13(4):543-6.
25. D'Amico M, etal., Gene. 2015 Aug 15;568(1):85-8. doi: 10.1016/j.gene.2015.05.034. Epub 2015 May 16.
26. Dan J, etal., Arch Ophthalmol. 2005 Feb;123(2):220-4.
27. Dorssers LC, etal., Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6194-202.
28. Dou YT, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Nov;31(11):1531-7.
29. Du YG, etal., Chin J Integr Med. 2015 Dec 28.
30. Duan J, etal., Evid Based Complement Alternat Med. 2015;2015:789027. doi: 10.1155/2015/789027. Epub 2015 Nov 29.
31. Dundar M, etal., Mod Rheumatol. 2013 Jan;23(1):140-5. doi: 10.1007/s10165-012-0687-9. Epub 2012 Jun 27.
32. East E, etal., Neuropathol Appl Neurobiol. 2008 Apr;34(2):216-30. Epub 2007 Nov 5.
33. Eissa DS and Ahmed TM, Blood Coagul Fibrinolysis. 2013 Mar;24(2):181-8. doi: 10.1097/MBC.0b013e32835b249d.
34. El Solh AA, etal., Intensive Care Med. 2006 Jan;32(1):110-5. Epub 2005 Nov 12.
35. Estellés A, etal., Blood. 1994 Jul 1;84(1):143-50.
36. Ezzidi I, etal., Diabetes Metab. 2009 Jun;35(3):214-9. doi: 10.1016/j.diabet.2008.12.002. Epub 2009 May 5.
37. Fan J, etal., Am J Respir Cell Mol Biol. 2000 Apr;22(4):412-21.
38. Farina A, etal., Prenat Diagn. 2006 Dec;26(12):1115-20.
39. Funk M, etal., Wien Klin Wochenschr. 2005 Oct;117(19-20):707-10.
40. Globocnik-Petrovic M, etal., Ophthalmologica. 2003 May-Jun;217(3):219-24.
41. Glueck CJ, etal., Clin Appl Thromb Hemost. 2005 Oct;11(4):375-89.
42. Glueck CJ, etal., Metabolism. 2000 Jul;49(7):845-52.
43. Gomez D, etal., Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2222-32. doi: 10.1161/ATVBAHA.113.301327. Epub 2013 Jun 27.
44. Gong R, etal., Arthritis Rheum. 2007 May;56(5):1608-17.
45. González F, etal., Metabolism. 2009 Jul;58(7):954-62. doi: 10.1016/j.metabol.2009.02.022.
46. Gori AM, etal., Thromb Haemost. 2004 Jul;92(1):54-60.
47. Gu J, etal., J Ethnopharmacol. 2016 Apr 20. pii: S0378-8741(16)30217-3. doi: 10.1016/j.jep.2016.04.024.
48. Gurgey A, etal., Blood Coagul Fibrinolysis. 2003 Feb;14(2):121-4.
49. Gutierrez LS, etal., Cancer Res. 2000 Oct 15;60(20):5839-47.
50. Haapaniemi E, etal., Acta Neurochir Suppl. 2000;76:277-8.
51. Haitsma JJ, etal., Eur Respir J. 2008 Dec;32(6):1599-606. doi: 10.1183/09031936.00045908. Epub 2008 Sep 3.
52. Han XD, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2007 May;30(5):363-7.
53. He L, etal., Evid Based Complement Alternat Med. 2009 Aug 25.
54. Hua H, etal., Allergol Immunopathol (Madr). 2011 Jul-Aug;39(4):206-11. doi: 10.1016/j.aller.2010.09.010. Epub 2011 Feb 19.
55. Huang Y, etal., J Clin Invest. 2003 Aug;112(3):379-88.
56. Hundsdorfer B, etal., J Craniomaxillofac Surg. 2005 Jun;33(3):191-6. Epub 2005 Apr 22.
57. Iijima H, etal., Am J Ophthalmol. 1999 Apr;127(4):477-8.
58. Imperatore F, etal., Intensive Care Med. 2006 Nov;32(11):1881-8. Epub 2006 Sep 15.
59. Ishidoya S, etal., J Urol. 2002 Mar;167(3):1503-7.
60. Iversen PO, etal., Thromb Haemost. 2010 Aug;104(2):350-4. doi: 10.1160/TH09-12-0816. Epub 2010 Jun 10.
61. Jiang JS, etal., Respiration. 2010;80(3):246-53. Epub 2010 Jan 28.
62. Jung ES, etal., Nephrology (Carlton). 2016 Feb 11. doi: 10.1111/nep.12747.
63. Kameyama H, etal., Leg Med (Tokyo). 2015 Jul;17(4):255-60. doi: 10.1016/j.legalmed.2015.02.007. Epub 2015 Mar 7.
64. Karásek D, etal., Thromb Res. 2009;123(3):466-75. doi: 10.1016/j.thromres.2008.02.011. Epub 2008 Apr 16.
65. Katta S, etal., Indian J Hum Genet. 2008 May;14(2):37-40.
66. Kenichi M, etal., J Lab Clin Med. 2004 Aug;144(2):69-77.
67. Kietzmann T, etal., Thromb Haemost. 2003 Apr;89(4):666-73.
68. Kim KK, etal., Mol Med. 2003 Jan-Feb;9(1-2):52-6.
69. Kimura H, etal., Kidney Int. 1998 Nov;54(5):1659-69.
70. Kobayashi N, etal., J Pharmacol Exp Ther. 2002 May;301(2):459-66.
71. Kouri FM, etal., Int J Biochem Cell Biol. 2008;40(9):1872-82. Epub 2008 Feb 2.
72. Kucharewicz I, etal., Int Arch Allergy Immunol. 2008;147(3):190-6. Epub 2008 Jul 2.
73. Kung CW, etal., Thromb Res. 2011 Jun;127(6):582-8. Epub 2011 Mar 10.
74. Lambert V, etal., FASEB J. 2001 Apr;15(6):1021-7.
75. Lambert V, etal., Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2791-7.
76. Lang H, etal., Arch Med Res. 2016 Mar 24. pii: S0188-4409(16)30002-9. doi: 10.1016/j.arcmed.2016.03.002.
77. Laudes IJ, etal., Am J Pathol. 2002 May;160(5):1867-75.
78. Lee YM, etal., Molecules. 2015 Nov 19;20(11):20699-708. doi: 10.3390/molecules201119728.
79. Lemaire R, etal., Arthritis Rheumatol. 2016 Feb;68(2):473-83. doi: 10.1002/art.39443.
80. Letson HL and Dobson GP, Thromb Res. 2016 Mar 7;141:58-65. doi: 10.1016/j.thromres.2016.03.007.
81. Li CF, etal., Fam Cancer. 2007;6(1):89-95.
82. Li DD, etal., J Neurol Sci. 2015 Mar 15;350(1-2):84-9. doi: 10.1016/j.jns.2015.02.022. Epub 2015 Feb 17.
83. Lin Q, etal., Zhonghua Yi Xue Za Zhi. 2005 Jun 22;85(23):1618-24.
84. Liu X, etal., World J Gastroenterol. 2014 Dec 28;20(48):18249-59. doi: 10.3748/wjg.v20.i48.18249.
85. Longstaff C and Kolev K, J Thromb Haemost. 2015 Jun;13 Suppl 1:S98-105. doi: 10.1111/jth.12935.
86. Lopes Barreto D, etal., Am J Kidney Dis. 2015 May;65(5):748-53. doi: 10.1053/j.ajkd.2014.10.022. Epub 2014 Dec 17.
87. Ma D, etal., Blood. 1997 Oct 1;90(7):2738-46.
88. Madach K, etal., Crit Care. 2010;14(2):R79. Epub 2010 Apr 29.
89. Magnussen S, etal., PLoS One. 2014 Jul 7;9(7):e101895. doi: 10.1371/journal.pone.0101895. eCollection 2014.
90. Mansfield MW, etal., Thromb Haemost. 1994 Jun;71(6):731-6.
91. Margaglione M, etal., Arterioscler Thromb Vasc Biol. 1998 Feb;18(2):152-6.
92. Maser RE, etal., J Diabetes Complications. 1997 Jul-Aug;11(4):243-9.
93. Matsushita K, etal., Lab Invest. 2016 Mar 21. doi: 10.1038/labinvest.2016.42.
94. Matsushita M, etal., Clin Exp Immunol. 2005 Mar;139(3):429-38.
95. Mehra R, etal., Am J Respir Crit Care Med. 2010 Sep 15;182(6):826-33. Epub 2010 May 27.
96. Mehta P and Parker RI, J Pediatr Hematol Oncol. 2010 Oct;32(7):532-6. doi: 10.1097/MPH.0b013e3181e0d152.
97. Meigs JB, etal., Obesity (Silver Spring). 2006 May;14(5):753-8.
98. MGD and Homologene mouse data transfer
99. MGD data from the GO Consortium
100. MGD IEA
101. Michineau S, etal., Eur J Vasc Endovasc Surg. 2010 Jun 14.
102. Milbrandt EB, etal., Mol Med. 2009 Nov-Dec;15(11-12):438-45. Epub 2009 Sep 8.
103. Mo JW, etal., Genet Mol Res. 2015 Oct 30;14(4):13835-42. doi: 10.4238/2015.October.29.3.
104. Mori Y, etal., Endocr J. 2003 Oct;50(5):603-11.
105. Mutoh M, etal., Carcinogenesis. 2008 Apr;29(4):824-9. doi: 10.1093/carcin/bgn028. Epub 2008 Feb 6.
106. Naderi J, etal., Am J Pathol. 2009 Aug;175(2):763-71. Epub 2009 Jul 2.
107. Naito Y, etal., J Hypertens. 2003 Jun;21(6):1107-15.
108. Nakajima T, etal., Pancreas. 2007 May;34(4):410-6.
109. Nobukata H, etal., Metabolism. 2000 Jul;49(7):912-9.
110. Offersen BV, etal., Lung Cancer. 2007 Apr;56(1):43-50. Epub 2007 Jan 17.
111. Ogata Y, etal., Tohoku J Exp Med. 2002 Jul;197(3):159-68.
112. Oikawa T, etal., Kidney Int. 1997 Jan;51(1):164-72.
113. Okada M, etal., FASEB J. 2001 Dec;15(14):2757-9. Epub 2001 Oct 15.
114. Okajima K, etal., Thromb Haemost. 2002 Sep;88(3):473-80.
115. OMIM Disease Annotation Pipeline
116. Ong K, etal., Thromb Haemost 2000 Dec;84(6):1023-30.
117. Onodera H, etal., Tohoku J Exp Med. 1999 Dec;189(4):259-65.
118. Orem A, etal., Ann Rheum Dis. 1995 Sep;54(9):726-9.
119. Ozbek OY, etal., Allergy Asthma Proc. 2009 Jan-Feb;30(1):41-6. Epub 2008 Dec 6.
120. Ozcan MA, etal., Thromb Res. 2003 Jun 1;110(4):243-7.
121. Pan F, etal., Chin J Integr Med. 2015 May 13.
122. Pan J, etal., BMC Complement Altern Med. 2015 Aug 19;15:291. doi: 10.1186/s12906-015-0808-z.
123. Penn JS and Rajaratnam VS, Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5423-9.
124. Penn JS, etal., Invest Ophthalmol Vis Sci. 2001 Jan;42(1):283-90.
125. Pipeline to import KEGG annotations from KEGG into RGD
126. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
127. Pontrelli P, etal., Transplantation. 2008 Jan 15;85(1):125-34. doi: 10.1097/01.tp.0000296831.91303.9a.
128. Prabhakaran P, etal., Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L20-8. Epub 2003 May 2.
129. Pretorius M, etal., Circulation. 2007 Sep 11;116(11 Suppl):I1-7.
130. Qiu P, etal., J Infect Dis. 2013 Sep;208(6):978-89. doi: 10.1093/infdis/jit247. Epub 2013 Jun 3.
131. Radenkovic D, etal., Pancreas. 2004 Aug;29(2):152-6.
132. Renckens R, etal., Blood. 2007 Feb 15;109(4):1593-601. Epub 2006 Oct 10.
133. Revelo MP, etal., Nephrol Dial Transplant. 2005 Dec;20(12):2812-9. Epub 2005 Oct 12.
134. RGD automated import pipeline
135. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
136. RGD automated import pipeline for gene-chemical interactions
137. Ricart JM, etal., Br J Haematol. 2008 May;141(5):716-9. doi: 10.1111/j.1365-2141.2008.07078.x. Epub 2008 Mar 12.
138. Richardson MA, etal., J Pharmacol Exp Ther. 2008 Apr;325(1):17-26. doi: 10.1124/jpet.107.130609. Epub 2008 Jan 8.
139. Sangle GV, etal., Endocrinology. 2010 Sep;151(9):4455-66. doi: 10.1210/en.2010-0323. Epub 2010 Jul 14.
140. Sapru A, etal., Anesthesiology. 2009 May;110(5):1086-91.
141. Sapru A, etal., Intensive Care Med. 2010 Jan;36(1):157-63. Epub 2009 Oct 24.
142. Sartori MT, etal., Clin Appl Thromb Hemost. 2003 Oct;9(4):299-307.
143. Schoots IG, etal., Surgery. 2003 Apr;133(4):411-9.
144. Sciacca FL, etal., Clin Cancer Res. 2004 Feb 15;10(4):1312-7.
145. Seferovic MD and Gupta MB, Dis Markers. 2016;2016:7124186. doi: 10.1155/2016/7124186. Epub 2016 Jan 19.
146. Sejima T, etal., Am J Rhinol Allergy. 2011 Jan-Feb;25(1):1-6.
147. Serrano R, etal., Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1563-9. doi: 10.1152/ajpregu.00093.2009. Epub 2009 Sep 23.
148. Simone TM, etal., Cell Signal. 2015 May;27(5):923-33. doi: 10.1016/j.cellsig.2015.01.009. Epub 2015 Jan 22.
149. Sirén V, etal., Acta Neurochir (Wien). 2004 Feb;146(2):111-8. Epub 2003 Dec 22.
150. Sogutlu Sari E, etal., Cutan Ocul Toxicol. 2014 Jan 22.
151. Srinivasan R, etal., Pediatr Crit Care Med. 2010 May 13.
152. Tabor CM, etal., Part Fibre Toxicol. 2016 Feb 9;13(1):6. doi: 10.1186/s12989-016-0116-x.
153. Takada Y, etal., Thromb Res. 1993 Sep 1;71(5):405-15.
154. Tanaka T, etal., Mol Cell Biochem. 2007 May;299(1-2):23-35.
155. Tarnow L, etal., Nephrol Dial Transplant. 2000 May;15(5):625-30.
156. Teesalu T, etal., Am J Pathol. 2001 Dec;159(6):2227-37.
157. Toblli JE, etal., Heart. 2005 Jan;91(1):80-6.
158. Tsai HJ, etal., Blood Coagul Fibrinolysis. 2015 Mar;26(2):175-84. doi: 10.1097/MBC.0000000000000214.
159. Tsantes AE, etal., Thromb Haemost. 2007 Jun;97(6):907-13.
160. Tsimperidis AG, etal., Scand J Gastroenterol. 2015 Jul;50(7):848-55. doi: 10.3109/00365521.2015.1010568. Epub 2015 Feb 5.
161. Ujhelyi B, etal., Thyroid. 2012 Apr;22(4):407-14. doi: 10.1089/thy.2011.0248. Epub 2012 Mar 2.
162. Urano T, etal., Jpn J Physiol. 1993;43(2):221-8.
163. Wahrenberg H, etal., Eur J Endocrinol. 2002 May;146(5):607-11.
164. Wang JJ, etal., Ophthalmology. 2008 Apr;115(4):693-9. Epub 2007 Aug 2.
165. Ware LB, etal., Crit Care Med. 2007 Aug;35(8):1821-8.
166. Witkowski P, etal., J Cardiovasc Pharmacol. 2007 Dec;50(6):633-40.
167. Wu J, etal., Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1565-70. doi: 10.1161/ATVBAHA.109.189514. Epub 2009 Jul 2.
168. Wu X, etal., Am J Physiol Regul Integr Comp Physiol. 2016 Feb 15;310(4):R323-9. doi: 10.1152/ajpregu.00401.2015. Epub 2015 Dec 2.
169. Xiang G, etal., J Am Coll Cardiol. 2005 Aug 2;46(3):536-41.
170. Xue H, etal., Biosci Rep. 2016 Apr 19. pii: BSR20160035.
171. Yamada Y, etal., N Engl J Med. 2002 Dec 12;347(24):1916-23.
172. Yamashita M Thromb Res. 1997 Aug 1;87(3):323-9.
173. Yan S, etal., J Obstet Gynaecol Res. 2015 Dec;41(12):1942-50. doi: 10.1111/jog.12807. Epub 2015 Sep 30.
174. Yanai H, etal., Diabetes Care. 2008 Oct;31(10):e72. doi: 10.2337/dc08-1228.
175. Yang D, etal., J Neurosci. 2009 Jul 8;29(27):8669-74.
176. You YP J Stroke Cerebrovasc Dis. 2016 Apr;25(4):990-7. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.014. Epub 2016 Feb 3.
177. Yung LM, etal., Am J Respir Crit Care Med. 2016 Apr 26.
178. Zamarron C, etal., Lung. 2008 May-Jun;186(3):151-6. Epub 2008 Mar 11.
179. Zhang JF, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2014 Aug;16(8):810-3.
180. Zhang T, etal., BMC Med. 2013 Jan 2;11:1. doi: 10.1186/1741-7015-11-1.
181. Zhang YP and Ma JY, Beijing Da Xue Xue Bao. 2005 Oct 18;37(5):516-9.
182. Zhang YP, etal., Acta Pharmacol Sin. 2012 Jul;33(7):897-908. doi: 10.1038/aps.2012.39. Epub 2012 Jun 4.
183. Zhang ZH, etal., Sci Rep. 2016 Feb 23;6:22151. doi: 10.1038/srep22151.
184. Zhao G, etal., Neuroreport. 2003 Sep 15;14(13):1689-92.
185. Zhong ZL and Chen S, Exp Diabetes Res. 2012;2012:350852. doi: 10.1155/2012/350852. Epub 2012 Oct 14.
Additional References at PubMed
PMID:2406566   PMID:7523120   PMID:7743917   PMID:8254028   PMID:8254029   PMID:8397803   PMID:8424466   PMID:8550840   PMID:8550848   PMID:8560424   PMID:8618918   PMID:8639841  
PMID:8662686   PMID:8798151   PMID:8816919   PMID:8939962   PMID:8959348   PMID:9033272   PMID:9119016   PMID:9386191   PMID:9427542   PMID:9701244   PMID:9701458   PMID:9727060  
PMID:9733098   PMID:9892694   PMID:10318667   PMID:10349636   PMID:10368124   PMID:10515791   PMID:10627465   PMID:10712412   PMID:10716993   PMID:10752934   PMID:10821760   PMID:10891445  
PMID:10992299   PMID:11042159   PMID:11076861   PMID:11104787   PMID:11110693   PMID:11141484   PMID:11157667   PMID:11213252   PMID:11217851   PMID:11441025   PMID:11470783   PMID:11473641  
PMID:11481248   PMID:11557572   PMID:11641723   PMID:11696429   PMID:11779826   PMID:11792849   PMID:11818362   PMID:11884297   PMID:12067901   PMID:12070304   PMID:12074598   PMID:12208516  
PMID:12414527   PMID:12466851   PMID:12477932   PMID:12482822   PMID:12524228   PMID:12536348   PMID:12598326   PMID:12603314   PMID:12702502   PMID:12761249   PMID:12818888   PMID:12832488  
PMID:12853975   PMID:12875966   PMID:12897066   PMID:14512369   PMID:14581407   PMID:14625301   PMID:14645112   PMID:14747283   PMID:14963029   PMID:14982862   PMID:15116271   PMID:15131125  
PMID:15166500   PMID:15242553   PMID:15284078   PMID:15286708   PMID:15297377   PMID:15308506   PMID:15328353   PMID:15361354   PMID:15562441   PMID:15569940   PMID:15674349   PMID:15716324  
PMID:15780082   PMID:15869599   PMID:15886793   PMID:15944322   PMID:15946208   PMID:15978095   PMID:15978107   PMID:16141072   PMID:16141073   PMID:16144810   PMID:16148154   PMID:16148222  
PMID:16160004   PMID:16194205   PMID:16221737   PMID:16250054   PMID:16314510   PMID:16316341   PMID:16373605   PMID:16427606   PMID:16460449   PMID:16514083   PMID:16528256   PMID:16601674  
PMID:16625420   PMID:16676075   PMID:16735799   PMID:16750510   PMID:16785241   PMID:16813566   PMID:16839355   PMID:16843437   PMID:16879220   PMID:16887829   PMID:16931518   PMID:16940168  
PMID:16943282   PMID:16985520   PMID:17018527   PMID:17022820   PMID:17062126   PMID:17067365   PMID:17068293   PMID:17082641   PMID:17114493   PMID:17230448   PMID:17415547   PMID:17429342  
PMID:17431190   PMID:17439629   PMID:17495424   PMID:17561000   PMID:17576591   PMID:17596132   PMID:17652357   PMID:17656680   PMID:17717143   PMID:17723219   PMID:17726492   PMID:17848179  
PMID:17888748   PMID:17932317   PMID:17938813   PMID:17958748   PMID:18095342   PMID:18216319   PMID:18255094   PMID:18276785   PMID:18359942   PMID:18395096   PMID:18469330   PMID:18551132  
PMID:18554148   PMID:18559377   PMID:18597060   PMID:18614541   PMID:18622550   PMID:18689689   PMID:18723692   PMID:18753414   PMID:18800031   PMID:18813358   PMID:18820962   PMID:18835034  
PMID:18925475   PMID:18957535   PMID:18990706   PMID:19060228   PMID:19098125   PMID:19106220   PMID:19122176   PMID:19144865   PMID:19168071   PMID:19190826   PMID:19338064   PMID:19429749  
PMID:19461880   PMID:19487690   PMID:19492148   PMID:19498055   PMID:19604604   PMID:19628967   PMID:19718486   PMID:19745198   PMID:19786738   PMID:19812386   PMID:19855083   PMID:19887897  
PMID:20009036   PMID:20133625   PMID:20133900   PMID:20147383   PMID:20171267   PMID:20185832   PMID:20203062   PMID:20228065   PMID:20232379   PMID:20300183   PMID:20351105   PMID:20492459  
PMID:20501949   PMID:20519507   PMID:20522601   PMID:20561659   PMID:20810696   PMID:20823384   PMID:20854792   PMID:20969520   PMID:21042733   PMID:21119013   PMID:21139380   PMID:21146630  
PMID:21239537   PMID:21267068   PMID:21354214   PMID:21423135   PMID:21496886   PMID:21501583   PMID:21546607   PMID:21571686   PMID:21596853   PMID:21622848   PMID:21667402   PMID:21707474  
PMID:21724997   PMID:21734232   PMID:21757225   PMID:21768189   PMID:21819560   PMID:21829547   PMID:21873635   PMID:21880664   PMID:21926267   PMID:21945446   PMID:21969564   PMID:22046433  
PMID:22078208   PMID:22178065   PMID:22213800   PMID:22262246   PMID:22293605   PMID:22307671   PMID:22383705   PMID:22432023   PMID:22484384   PMID:22507835   PMID:22560297   PMID:22563394  
PMID:22570200   PMID:22572461   PMID:22573404   PMID:22658637   PMID:22723298   PMID:22912336   PMID:22952059   PMID:22982464   PMID:22984202   PMID:23079293   PMID:23082983   PMID:23213481  
PMID:23218129   PMID:23249568   PMID:23254194   PMID:23340304   PMID:23408987   PMID:23454124   PMID:23461356   PMID:23487423   PMID:23494120   PMID:23565059   PMID:23657855   PMID:23665346  
PMID:23708702   PMID:23712751   PMID:23715621   PMID:23724005   PMID:23770230   PMID:23776165   PMID:23800036   PMID:23816469   PMID:23894536   PMID:23919993   PMID:23940734   PMID:23991045  
PMID:24006456   PMID:24019535   PMID:24024554   PMID:24107419   PMID:24155177   PMID:24172014   PMID:24212262   PMID:24269585   PMID:24425831   PMID:24440681   PMID:24478370   PMID:24605827  
PMID:24651693   PMID:24655755   PMID:24667608   PMID:24709679   PMID:24778222   PMID:24929950   PMID:24962629   PMID:24987792   PMID:25041188   PMID:25077763   PMID:25106729   PMID:25356654  
PMID:25399881   PMID:25447049   PMID:25451236   PMID:25454795   PMID:25552599   PMID:25587125   PMID:25613478   PMID:25673638   PMID:25679759   PMID:25694133   PMID:25715398   PMID:25740294  
PMID:25799354   PMID:25932922   PMID:26032256   PMID:26053644   PMID:26349765   PMID:26416771   PMID:26471094   PMID:26747783   PMID:26984772   PMID:27038741   PMID:27106291   PMID:27120339  
PMID:27283026   PMID:27317488   PMID:27377187   PMID:27404230   PMID:27436577   PMID:27659097   PMID:27770432   PMID:27793937   PMID:27906548   PMID:27924807   PMID:28132883   PMID:28270519  
PMID:28273432   PMID:28321652   PMID:28336948   PMID:28385810   PMID:28432216   PMID:28445073   PMID:28588076   PMID:28684544   PMID:28693719   PMID:28722352   PMID:28821477   PMID:28893232  
PMID:28899878   PMID:28924605   PMID:29028290   PMID:29371242   PMID:29391420   PMID:29454747   PMID:29477725   PMID:29534207   PMID:29561836   PMID:29584619   PMID:29643421   PMID:29978354  
PMID:30087332   PMID:30124738   PMID:30220231   PMID:30387130   PMID:30463014   PMID:30532990   PMID:30566624   PMID:30842312   PMID:30855280   PMID:31054988   PMID:31230745   PMID:31424116  
PMID:31513752   PMID:31610810   PMID:31676865   PMID:32001531   PMID:32024545   PMID:32142912   PMID:32178735   PMID:32272863   PMID:32325033   PMID:32657780   PMID:33097058   PMID:33673196  
PMID:33866038   PMID:33904394  


Genomics

Comparative Map Data
Serpine1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,090,358 - 137,101,126 (-)NCBIGRCm39mm39
GRCm39 Ensembl5137,090,358 - 137,101,122 (-)Ensembl
GRCm385137,061,504 - 137,072,272 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,061,504 - 137,072,268 (-)EnsemblGRCm38mm10GRCm38
MGSCv375137,537,374 - 137,548,142 (-)NCBIGRCm37mm9NCBIm37
MGSCv365137,346,135 - 137,356,886 (-)NCBImm8
Celera5134,078,340 - 134,089,224 (-)NCBICelera
Cytogenetic Map5G2NCBI
SERPINE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7101,127,104 - 101,139,247 (+)EnsemblGRCh38hg38GRCh38
GRCh387101,127,104 - 101,139,247 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,770,385 - 100,782,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,557,172 - 100,569,026 (+)NCBINCBI36hg18NCBI36
Build 347100,363,886 - 100,375,741NCBI
Celera795,778,744 - 95,790,926 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef795,363,553 - 95,375,745 (+)NCBIHuRef
CHM1_17100,700,705 - 100,712,867 (+)NCBICHM1_1
CRA_TCAGchr7v27100,128,757 - 100,140,934 (+)NCBI
Serpine1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21219,601,272 - 19,611,657 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1219,601,272 - 19,611,657 (+)Ensembl
Rnor_6.01222,641,104 - 22,651,482 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,641,104 - 22,651,482 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,653,385 - 24,663,763 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,931,996 - 20,942,374 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11220,921,607 - 20,931,986 (-)NCBI
Celera1221,377,028 - 21,387,410 (+)NCBICelera
RH 3.4 Map12277.5RGD
Cytogenetic Map12q12NCBI
Serpine1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545616,145,944 - 16,157,142 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545616,147,523 - 16,157,040 (-)NCBIChiLan1.0ChiLan1.0
SERPINE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17106,511,539 - 106,518,605 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,510,130 - 106,518,450 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0793,267,517 - 93,279,728 (+)NCBIMhudiblu_PPA_v0panPan3
SERPINE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,719,547 - 8,727,160 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,720,825 - 8,726,301 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,418,147 - 10,423,482 (-)NCBI
ROS_Cfam_1.068,538,810 - 8,546,429 (-)NCBI
UMICH_Zoey_3.168,500,159 - 8,505,509 (-)NCBI
UNSW_CanFamBas_1.068,470,611 - 8,475,963 (-)NCBI
UU_Cfam_GSD_1.068,635,341 - 8,640,693 (-)NCBI
Serpine1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,997,052 - 133,003,714 (-)NCBI
SpeTri2.0NW_0049365431,032,543 - 1,040,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,863,695 - 8,871,564 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,863,738 - 8,871,572 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SERPINE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,047,520 - 12,060,662 (-)NCBI
ChlSab1.1 Ensembl2812,047,529 - 12,060,202 (-)Ensembl
Vero_WHO_p1.0NW_0236660704,295,672 - 4,308,796 (+)NCBI
Serpine1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474016,128,145 - 16,136,696 (-)NCBI

Position Markers
M33960  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,062,673 - 137,062,870UniSTSGRCm38
MGSCv375137,538,543 - 137,538,740UniSTSGRCm37
Celera5134,079,515 - 134,079,712UniSTS
Cytogenetic Map5G2UniSTS
Whitehead/MRC_RH51650.52UniSTS
Whitehead_YAC5 UniSTS
PMC15197P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,063,016 - 137,063,520UniSTSGRCm38
MGSCv375137,538,886 - 137,539,390UniSTSGRCm37
Celera5134,079,858 - 134,080,362UniSTS
Cytogenetic Map5G2UniSTS
Serpine1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5G2UniSTS
cM Map5 UniSTS
Serpine1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5G2UniSTS
M33960  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,062,950 - 137,063,042UniSTSGRCm38
MGSCv375137,538,820 - 137,538,912UniSTSGRCm37
Celera5134,079,792 - 134,079,884UniSTS
Cytogenetic Map5G2UniSTS
Whitehead/MRC_RH51650.52UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125101165141714711Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121556974151834684Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124714580151834684Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129583274151834684Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125147702151834684Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119806972141714711Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5134002093151834684Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121457140151834684Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129851021151834684Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir143mmu-miR-143-3pOncomiRDBexternal_infoNANA22108519
Mir486mmu-miR-486-5pOncomiRDBexternal_infoNANA22995304

Predicted Target Of
Summary Value
Count of predictions:1075
Count of miRNA genes:400
Interacting mature miRNAs:454
Transcripts:ENSMUST00000041388, ENSMUST00000077523
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000041388   ⟹   ENSMUSP00000039586
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,090,358 - 137,101,113 (-)Ensembl
GRCm38.p6 Ensembl5137,061,504 - 137,072,259 (-)Ensembl
RefSeq Acc Id: ENSMUST00000077523   ⟹   ENSMUSP00000076728
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,090,366 - 137,101,108 (-)Ensembl
GRCm38.p6 Ensembl5137,061,512 - 137,072,254 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199832
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,099,031 - 137,101,122 (-)Ensembl
GRCm38.p6 Ensembl5137,070,177 - 137,072,268 (-)Ensembl
RefSeq Acc Id: NM_008871   ⟹   NP_032897
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,090,358 - 137,101,126 (-)NCBI
GRCm385137,061,504 - 137,072,272 (-)ENTREZGENE
MGSCv375137,537,374 - 137,548,142 (-)RGD
Celera5134,078,340 - 134,089,224 (-)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032897   ⟸   NM_008871
- Peptide Label: precursor
- UniProtKB: G5E899 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000039586   ⟸   ENSMUST00000041388
RefSeq Acc Id: ENSMUSP00000076728   ⟸   ENSMUST00000077523
Protein Domains
SERPIN

Promoters
RGD ID:6888404
Promoter ID:EPDNEW_M7653
Type:multiple initiation site
Name:Serpine1_1
Description:Mus musculus serine peptidase inhibitor, clade E, member 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385137,072,268 - 137,072,328EPDNEW
RGD ID:6849194
Promoter ID:MM_XEF:5726
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_2Hour,   Lung,   MEF_B4
Transcripts:NM_000602,   NM_001165413,   NM_001174114,   NM_174137,   NM_213910
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365137,546,836 - 137,547,417 (-)MPROMDB
RGD ID:6838316
Promoter ID:MM_KWN:44446
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000077523,   NM_008871,   UC009ABO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365137,547,756 - 137,548,817 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97608 AgrOrtholog
Ensembl Genes ENSMUSG00000037411 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000039586 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000076728 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041388 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000077523 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Serpin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18787 UniProtKB/TrEMBL
MGD MGI:97608 ENTREZGENE
NCBI Gene 18787 ENTREZGENE
PANTHER PTHR11461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serpin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB SERPINE1 RGD
PhenoGen Serpine1 PhenoGen
PROSITE SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D0ESZ5_MOUSE UniProtKB/TrEMBL
  D0ESZ6_MOUSE UniProtKB/TrEMBL
  G5E899 ENTREZGENE, UniProtKB/TrEMBL
  P22777 ENTREZGENE, UniProtKB/Swiss-Prot
  Q7TPE9_MOUSE UniProtKB/TrEMBL