Phb (prohibitin) - Rat Genome Database

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Gene: Phb (prohibitin) Mus musculus
Analyze
Symbol: Phb
Name: prohibitin
RGD ID: 11096
MGI Page MGI
Description: Enables transcription corepressor activity. Involved in several processes, including CD40 signaling pathway; activation of phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within DNA biosynthetic process and negative regulation of transcription by RNA polymerase II. Located in several cellular components, including cell surface; mitochondrial inner membrane; and nucleus. Part of mitochondrial prohibitin complex. Is expressed in ectoplacental cone; embryo; and extraembryonic ectoderm. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Orthologous to human PHB1 (prohibitin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell receptor-associated protein 32; BAP32
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm11383   Gm14834   Gm15078   Gm4773   Gm4996   Gm7542   Gm7666   Gm8855   Gm9673  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391195,557,783 - 95,571,599 (+)NCBIGRCm39mm39
GRCm39 Ensembl1195,557,783 - 95,571,599 (+)Ensembl
GRCm381195,666,957 - 95,680,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,666,957 - 95,680,773 (+)EnsemblGRCm38mm10GRCm38
MGSCv371195,528,271 - 95,542,087 (+)NCBIGRCm37mm9NCBIm37
MGSCv361195,483,105 - 95,496,855 (+)NCBImm8
Celera11105,306,168 - 105,322,388 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(R)-adrenaline  (ISO)
(S)-nicotine  (EXP)
(Z)-3-butylidenephthalide  (ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxynon-2-enal  (ISO)
7,12-dimethyltetraphene  (ISO)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (ISO)
Brodifacoum  (ISO)
busulfan  (EXP)
cadmium dichloride  (ISO)
caffeine  (EXP)
calcitriol  (ISO)
cannabidiol  (ISO)
choline  (ISO)
chromium trinitrate  (EXP)
chromium(6+)  (EXP)
clobetasol  (EXP)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (ISO)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
diuron  (ISO)
dopamine  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eurycomanone  (ISO)
finasteride  (ISO)
flavone  (ISO)
flutamide  (ISO)
folic acid  (EXP)
genistein  (ISO)
geraniol  (ISO)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
ketamine  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
LY294002  (ISO)
malathion  (ISO)
menadione  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
miconazole  (EXP)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nicotine  (EXP)
nimesulide  (ISO)
ochratoxin A  (EXP,ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
pentachlorophenol  (EXP)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (EXP)
potassium dichromate  (ISO)
progesterone  (ISO)
pyrogallol  (EXP)
quinomethionate  (ISO)
rotenone  (EXP,ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
thapsigargin  (ISO)
Tributyltin oxide  (EXP)
triciribine  (ISO)
triptonide  (EXP)
tungsten  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of phospholipase C activity  (IDA)
activation of protein kinase C activity  (IDA)
animal organ regeneration  (ISO)
antiviral innate immune response  (ISO)
B cell activation  (IDA)
CD40 signaling pathway  (IDA)
cellular response to interleukin-6  (ISO)
DNA biosynthetic process  (IMP)
histone deacetylation  (ISO)
mitochondrion organization  (IBA,ISO)
modulation by host of viral RNA genome replication  (IDA)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of glucocorticoid receptor signaling pathway  (ISO)
negative regulation of protein catabolic process  (ISO)
negative regulation of transcription by competitive promoter binding  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,ISO)
negative regulation of transcription, DNA-templated  (ISO)
ovarian follicle atresia  (ISO)
ovarian follicle development  (ISO)
positive regulation of cell death  (ISO)
positive regulation of complement activation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of G protein-coupled receptor signaling pathway  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of immunoglobulin production  (IDA)
positive regulation of interleukin-17 production  (ISO)
positive regulation of NIK/NF-kappaB signaling  (IDA)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
progesterone receptor signaling pathway  (ISO)
protein stabilization  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to cytokine  (ISO)
response to ethanol  (ISO)
response to immobilization stress  (ISO)
response to peptide hormone  (ISO)
response to xenobiotic stimulus  (ISO)
RIG-I signaling pathway  (ISO)
T-helper 17 type immune response  (ISO)
viral entry into host cell  (IDA)

References

Additional References at PubMed
PMID:1684951   PMID:8070406   PMID:8449498   PMID:8591812   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11302691   PMID:11884367   PMID:12466851  
PMID:12477932   PMID:12520002   PMID:12865426   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15782199   PMID:15850985   PMID:16141072   PMID:16141073   PMID:16518872   PMID:16602821  
PMID:17324931   PMID:17363568   PMID:17597094   PMID:17634366   PMID:17932104   PMID:18480465   PMID:18614015   PMID:18614564   PMID:18799693   PMID:19013772   PMID:19372376   PMID:19854158  
PMID:19858219   PMID:20134482   PMID:20832420   PMID:20890892   PMID:20959514   PMID:21209023   PMID:21829624   PMID:21873635   PMID:22124450   PMID:22238093   PMID:22417827   PMID:22479600  
PMID:22537547   PMID:22869582   PMID:22951295   PMID:23241883   PMID:23494124   PMID:24023254   PMID:24085822   PMID:24457600   PMID:24856930   PMID:24947361   PMID:25226451   PMID:25501599  
PMID:26048717   PMID:26465331   PMID:26751773   PMID:26885862   PMID:27034005   PMID:27160897   PMID:27687727   PMID:27689697   PMID:28062948   PMID:28376086   PMID:28714328   PMID:29242126  
PMID:29324904   PMID:30049713   PMID:30068389   PMID:30196744   PMID:30457570   PMID:30550785   PMID:30562941   PMID:30595499   PMID:30713523   PMID:31162944   PMID:32111635   PMID:32152200  
PMID:32226526   PMID:32232334   PMID:32581705   PMID:32994313   PMID:33144683   PMID:33175859   PMID:34078899   PMID:34219469   PMID:34257070  


Genomics

Comparative Map Data
Phb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391195,557,783 - 95,571,599 (+)NCBIGRCm39mm39
GRCm39 Ensembl1195,557,783 - 95,571,599 (+)Ensembl
GRCm381195,666,957 - 95,680,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,666,957 - 95,680,773 (+)EnsemblGRCm38mm10GRCm38
MGSCv371195,528,271 - 95,542,087 (+)NCBIGRCm37mm9NCBIm37
MGSCv361195,483,105 - 95,496,855 (+)NCBImm8
Celera11105,306,168 - 105,322,388 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
PHB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1749,404,052 - 49,414,901 (-)EnsemblGRCh38hg38GRCh38
GRCh381749,404,052 - 49,414,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371747,481,414 - 47,492,244 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361744,836,419 - 44,847,241 (-)NCBINCBI36hg18NCBI36
Build 341744,836,418 - 44,847,241NCBI
Celera1743,936,440 - 43,947,262 (-)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1742,846,458 - 42,857,310 (-)NCBIHuRef
CHM1_11747,546,565 - 47,557,421 (-)NCBICHM1_1
Phb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21080,605,268 - 80,618,043 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1080,605,251 - 80,618,042 (+)Ensembl
Rnor_6.01083,476,107 - 83,488,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1083,476,107 - 83,488,878 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01083,284,048 - 83,296,819 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1199,127,730 - 9,128,666 (+)NCBI
Celera1079,373,802 - 79,386,571 (+)NCBICelera
Cytogenetic Map10q26NCBI
Phb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545112,110,290 - 12,120,124 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545112,110,290 - 12,119,870 (+)NCBIChiLan1.0ChiLan1.0
PHB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1178,175,912 - 8,186,790 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,175,968 - 8,186,790 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0178,189,555 - 8,200,491 (+)NCBIMhudiblu_PPA_v0panPan3
PHB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1925,525,711 - 25,536,722 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl925,526,649 - 25,536,722 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,985,397 - 24,996,403 (-)NCBI
ROS_Cfam_1.0926,321,934 - 26,332,949 (-)NCBI
ROS_Cfam_1.0 Ensembl926,185,622 - 26,347,114 (-)Ensembl
UMICH_Zoey_3.1925,089,828 - 25,100,839 (-)NCBI
UNSW_CanFamBas_1.0925,349,147 - 25,360,155 (-)NCBI
UU_Cfam_GSD_1.0925,478,042 - 25,489,037 (-)NCBI
Phb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560224,936,269 - 24,948,093 (-)NCBI
SpeTri2.0NW_00493649012,127,065 - 12,138,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1225,584,443 - 25,609,656 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11225,596,520 - 25,609,693 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21225,535,912 - 25,549,084 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11669,805,968 - 69,816,792 (-)NCBIChlSab1.1chlSab2
ChlSab1.11669,805,968 - 69,816,792 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1669,806,923 - 69,816,754 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607740,910,348 - 40,921,223 (-)NCBIVero_WHO_p1.0
Phb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247955,556,728 - 5,565,969 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
PMC152247P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37X130,588,154 - 130,588,954UniSTSGRCm37
MGSCv37156,603,923 - 6,604,741UniSTSGRCm37
Celera156,502,496 - 6,503,314UniSTS
CeleraX116,929,996 - 116,930,796UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map11DUniSTS
cM Map1155.6UniSTS
fb80e06.x1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381195,672,785 - 95,673,691UniSTSGRCm38
MGSCv371195,534,099 - 95,535,005UniSTSGRCm37
Celera11105,313,934 - 105,314,840UniSTS
Celera11105,311,381 - 105,312,275UniSTS
Cytogenetic Map11DUniSTS
cM Map1155.6UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187800372103383289Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118880876299190771Mouse
1301313Pas5a_mpulmonary adenoma susceptibility 5a (mouse)Not determined118907597898974942Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
1300847Par1_mpulmonary adenoma resistance 1 (mouse)Not determined119417295396276595Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
4141086Mvwf_mmodifier of von Willebrand factor (mouse)Not determined9556881896285776Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir27ammu-miR-27a-3pOncomiRDBexternal_infoNANA18789835
Mir27ammu-miR-27a-3pOncomiRDBexternal_infoNANA22505583

Predicted Target Of
Summary Value
Count of predictions:855
Count of miRNA genes:547
Interacting mature miRNAs:637
Transcripts:ENSMUST00000036374, ENSMUST00000123001, ENSMUST00000123071, ENSMUST00000125172, ENSMUST00000127031
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK002714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW457788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM935516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY333636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000036374   ⟹   ENSMUSP00000047536
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1195,557,890 - 95,570,534 (+)Ensembl
GRCm38.p6 Ensembl1195,667,064 - 95,679,708 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123001
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1195,562,276 - 95,566,886 (+)Ensembl
GRCm38.p6 Ensembl1195,671,450 - 95,676,060 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123071
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1195,557,826 - 95,562,468 (+)Ensembl
GRCm38.p6 Ensembl1195,667,000 - 95,671,642 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125172   ⟹   ENSMUSP00000119603
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1195,557,783 - 95,571,599 (+)Ensembl
GRCm38.p6 Ensembl1195,666,957 - 95,680,773 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1195,557,836 - 95,559,439 (+)Ensembl
GRCm38.p6 Ensembl1195,667,010 - 95,668,613 (+)Ensembl
RefSeq Acc Id: NM_008831   ⟹   NP_032857
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391195,557,783 - 95,571,599 (+)NCBI
GRCm381195,666,957 - 95,680,773 (+)ENTREZGENE
MGSCv371195,528,271 - 95,542,087 (+)RGD
Celera11105,306,168 - 105,322,388 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032857   ⟸   NM_008831
- UniProtKB: P67778 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000119603   ⟸   ENSMUST00000125172
RefSeq Acc Id: ENSMUSP00000047536   ⟸   ENSMUST00000036374
Protein Domains
PHB

Promoters
RGD ID:6821540
Promoter ID:MM_KWN:9344
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000003483,   OTTMUST00000003484,   OTTMUST00000003485,   OTTMUST00000003486
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361195,527,896 - 95,528,452 (+)MPROMDB
RGD ID:8676278
Promoter ID:EPDNEW_M16170
Type:multiple initiation site
Name:Phb_1
Description:Mus musculus prohibitin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381195,667,000 - 95,667,060EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97572 AgrOrtholog
Ensembl Genes ENSMUSG00000038845 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000047536 UniProtKB/TrEMBL
  ENSMUSP00000119603 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036374 UniProtKB/TrEMBL
  ENSMUST00000125172 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.479.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Band_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Band_7/SPFH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prohibitin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18673 UniProtKB/Swiss-Prot
MGD MGI:97572 ENTREZGENE
NCBI Gene 18673 ENTREZGENE
PANTHER PTHR23222 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Band_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phb PhenoGen
PRINTS PROHIBITIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PHB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117892 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P67778 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TV00_MOUSE UniProtKB/TrEMBL
  Q5SQG5_MOUSE UniProtKB/TrEMBL
UniProt Secondary P24142 UniProtKB/Swiss-Prot
  Q3UB75 UniProtKB/Swiss-Prot
  Q5SQG4 UniProtKB/Swiss-Prot