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Gene: Phb (prohibitin) Mus musculus
Symbol: Phb
Name: prohibitin
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in DNA biosynthetic process and negative regulation of transcription by RNA polymerase II. Localizes to cell surface; mitochondrial inner membrane; and nucleus. Is expressed in ectoplacental cone; embryo; and extraembryonic ectoderm. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Orthologous to human PHB (prohibitin); INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell receptor-associated protein 32; BAP32
Homo sapiens (human) : PHB (prohibitin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Phb (prohibitin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phb (prohibitin)
Pan paniscus (bonobo/pygmy chimpanzee) : PHB (prohibitin)
Canis lupus familiaris (dog) : PHB (prohibitin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phb (prohibitin)
Sus scrofa (pig) : PHB (prohibitin)
Chlorocebus sabaeus (African green monkey) : PHB (prohibitin)
Heterocephalus glaber (naked mole-rat) : Phb (prohibitin)
more info ...
Related Pseudogenes: Gm11383   Gm14834   Gm15078   Gm4773   Gm4996   Gm7542   Gm7666   Gm8855   Gm9673  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1195,666,957 - 95,680,773 (+)EnsemblGRCm38mm10GRCm38
GRCm381195,666,957 - 95,680,773 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371195,528,271 - 95,542,087 (+)NCBIGRCm37mm9NCBIm37
MGSCv361195,483,105 - 95,496,855 (+)NCBImm8
Celera11105,306,168 - 105,322,388 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Phb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11096
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.