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Gene: Mcam (melanoma cell adhesion molecule) Mus musculus
Symbol: Mcam
Name: melanoma cell adhesion molecule
Description: Predicted to be involved in angiogenesis; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and positive regulation of cell migration. Predicted to localize to the external side of plasma membrane; extracellular space; and nucleus. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and respiratory system. Orthologous to human MCAM (melanoma cell adhesion molecule); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-gicerin; AV025631; CD146; CD149; cell surface glycoprotein MUC18; gicerin; l-gicerin protein; melanoma adhesion molecule; melanoma-associated antigen MUC18; Muc18; s-endo; s-gicerin
Homo sapiens (human) : MCAM (melanoma cell adhesion molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mcam (melanoma cell adhesion molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcam (melanoma cell adhesion molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : MCAM (melanoma cell adhesion molecule)
Canis lupus familiaris (dog) : MCAM (melanoma cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcam (melanoma cell adhesion molecule)
Sus scrofa (pig) : MCAM (melanoma cell adhesion molecule)
Chlorocebus sabaeus (green monkey) : MCAM (melanoma cell adhesion molecule)
Heterocephalus glaber (naked mole-rat) : Mcam (melanoma cell adhesion molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl944,134,469 - 44,142,727 (+)Ensembl
GRCm38944,134,658 - 44,142,727 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37943,942,741 - 43,950,809 (+)NCBIGRCm37mm9NCBIm37
MGSCv36943,885,666 - 43,893,719 (+)NCBImm8
Celera941,392,205 - 41,400,272 (+)NCBICelera
Cytogenetic Map9 A5.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mcam
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732869
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.