Ccl3 (chemokine (C-C motif) ligand 3) - Rat Genome Database
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Gene: Ccl3 (chemokine (C-C motif) ligand 3) Mus musculus
Analyze
Symbol: Ccl3
Name: chemokine (C-C motif) ligand 3
RGD ID: 11276
MGI Page MGI
Description: Is expressed in lung. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL3 (C-C motif chemokine ligand 3); PARTICIPATES IN interleukin-12 signaling pathway; Chagas disease pathway; rheumatoid arthritis pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323804; C-C motif chemokine 3; CCL; G0S19-; G0S19-1; heparin-binding chemotaxis protein; L2G25B; LD78; LD78alpha; macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; Mi; MIP-; MIP-1 alpha; MIP-1-alpha; MIP-1alpha; MIP1; MIP1 (a); MIP1-; MIP1-(a); MIP1-alpha; Mip1a; Scy; Scya3; SIS-alpha; small inducible cytokine A3; small-inducible cytokine A3; TY-5
RGD Orthologs
Human
Rat
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,538,669 - 83,540,204 (-)NCBIGRCm39mm39
GRCm39 Ensembl1183,538,670 - 83,540,181 (-)Ensembl
GRCm381183,647,843 - 83,649,378 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,647,844 - 83,649,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,461,345 - 83,462,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv361183,464,040 - 83,465,552 (-)NCBImm8
Celera1193,252,227 - 93,253,762 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-pilocarpine  (EXP)
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-adrenaline  (EXP,ISO)
(R)-mevalonic acid  (ISO)
(R)-noradrenaline  (EXP)
1,4-benzoquinone  (ISO)
1,7-dimethylxanthine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
15-acetyldeoxynivalenol  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
26-hydroxycholesterol  (ISO)
3',5'-cyclic AMP  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-phenylprop-2-enal  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-nitroquinoline N-oxide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
7-ketocholesterol  (ISO)
7alpha-hydroxycholesterol  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
albendazole  (ISO)
albuterol  (ISO)
alclometasone dipropionate  (ISO)
aldehydo-D-glucosamine  (ISO)
alexidine  (ISO)
all-trans-retinoic acid  (ISO)
aluminium hydroxide  (ISO)
amiloride  (EXP)
ammonium chloride  (ISO)
amphibole asbestos  (ISO)
amprenavir  (ISO)
antimycin A  (ISO)
aripiprazole  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
asbestos  (ISO)
asperentin  (EXP)
atazanavir sulfate  (ISO)
ATP  (EXP)
azetidine  (EXP)
bathocuproine disulfonic acid  (ISO)
beclomethasone  (ISO)
benazepril  (ISO)
benzalkonium chloride  (EXP)
benzene  (EXP)
benzene-1,2,4-triol  (ISO)
benzethonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
beryllium sulfate  (ISO)
beta-D-glucosamine  (ISO)
betamethasone  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
bortezomib  (EXP,ISO)
bucladesine  (ISO)
budesonide  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
calcitriol  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabigerol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP,ISO)
carrageenan  (EXP)
catechol  (ISO)
cefaloridine  (ISO)
celastrol  (ISO)
ceric oxide  (ISO)
chenodeoxycholic acid  (EXP)
chloroethene  (EXP)
choline  (EXP)
cis-caffeic acid  (EXP)
citronellol  (ISO)
cobalt atom  (ISO)
cocaine  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclophosphamide  (EXP)
D-penicillamine  (ISO)
dapsone  (EXP)
deoxynivalenol  (EXP,ISO)
dequalinium  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP,ISO)
diarsenic trioxide  (ISO)
dichlorine  (EXP)
dichromium trioxide  (ISO)
diclofenac  (ISO)
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium  (ISO)
dioxygen  (EXP,ISO)
dobutamine  (ISO)
doxorubicin  (ISO)
edaravone  (ISO)
emetine  (ISO)
endosulfan  (ISO)
Erionite  (EXP)
ethanol  (EXP,ISO)
etoposide  (ISO)
eugenol  (ISO)
fenvalerate  (ISO)
ferric oxide  (ISO)
ferroheme b  (ISO)
Fexofenadine hydrochloride  (EXP)
fludrocortisone  (ISO)
flumequine  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (EXP)
gemcitabine  (ISO)
graphite  (EXP,ISO)
heme b  (ISO)
hesperidin  (ISO)
hexadecanoic acid  (ISO)
Honokiol  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
indinavir  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
kaempferol 3-O-beta-D-glucoside  (EXP)
kojic acid  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
lipid As  (EXP)
lipopolysaccharide  (EXP,ISO)
lopinavir  (ISO)
losartan  (ISO)
maraviroc  (ISO)
meclocycline  (ISO)
MeIQx  (EXP)
menadione  (ISO)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP)
mercury(0)  (EXP,ISO)
metam  (EXP)
methadone  (ISO)
methionine sulfoximine  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP)
mifepristone  (ISO)
minocycline  (ISO)
morphine  (ISO)
mycotoxin  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-methylformamide  (EXP)
N-nitrosodiethylamine  (EXP)
naphthalene  (EXP)
naproxen  (ISO)
naringin  (EXP)
nelfinavir  (ISO)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
niclosamide  (EXP)
nitrogen dioxide  (EXP)
o-anisidine  (ISO)
octadecanoic acid  (ISO)
oxaliplatin  (ISO)
oxytetracycline  (ISO)
ozone  (EXP,ISO)
palmatine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
perindopril  (EXP)
permethrin  (ISO)
phenanthridone  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (EXP,ISO)
poly(I:C)  (EXP)
polymyxin B2  (EXP)
prednisolone  (ISO)
progesterone  (ISO)
propanal  (ISO)
propidium  (ISO)
propranolol  (EXP,ISO)
prostaglandin E2  (EXP,ISO)
Pyridostigmine bromide  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quartz  (ISO)
quercetin  (EXP)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
rifaximin  (EXP)
rimonabant  (EXP)
ritonavir  (ISO)
rofecoxib  (EXP)
roflumilast  (ISO)
rolipram  (EXP)
SB 203580  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sterigmatocystin  (EXP)
streptozocin  (EXP)
succimer  (EXP)
sumatriptan  (ISO)
tamoxifen  (EXP)
taurocholic acid  (EXP)
Tesaglitazar  (ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thiostrepton  (ISO)
tigecycline  (ISO)
titanium dioxide  (EXP,ISO)
toluene  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (EXP)
tremolite asbestos  (EXP)
trimellitic anhydride  (EXP)
trimethyltin  (EXP)
troglitazone  (ISO)
tropisetron  (ISO)
tungsten  (ISO)
XL147  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte cell migration  (IDA)
calcium ion transport  (ISO)
calcium-mediated signaling  (ISO)
cell activation  (ISO)
cell-cell signaling  (ISO)
cellular calcium ion homeostasis  (ISO)
cellular response to interferon-gamma  (IBA,ISO)
cellular response to interleukin-1  (IBA,ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to tumor necrosis factor  (IBA,ISO)
chemokine-mediated signaling pathway  (IBA)
chemotaxis  (IEA,ISO)
cytoskeleton organization  (ISO)
eosinophil chemotaxis  (ISO)
eosinophil degranulation  (ISO)
exocytosis  (ISO)
G protein-coupled receptor signaling pathway  (IBA)
granulocyte chemotaxis  (ISO)
immune response  (IEA)
inflammatory response  (IBA,ISO)
leukocyte chemotaxis  (ISO)
lipopolysaccharide-mediated signaling pathway  (ISO)
lymphocyte chemotaxis  (IBA,ISO)
macrophage chemotaxis  (IGI)
MAPK cascade  (ISO)
monocyte chemotaxis  (IBA,ISO)
negative regulation by host of viral transcription  (ISO)
negative regulation of bone mineralization  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of osteoclast differentiation  (ISO)
neutrophil chemotaxis  (IBA,ISO)
osteoblast differentiation  (ISO)
positive regulation of calcium ion transport  (ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA,ISO)
positive regulation of gene expression  (ISO)
positive regulation of GTPase activity  (IBA)
positive regulation of inflammatory response  (IGI)
positive regulation of interleukin-1 beta production  (IGI)
positive regulation of natural killer cell chemotaxis  (ISO)
positive regulation of neuron apoptotic process  (IGI)
positive regulation of osteoclast differentiation  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of transcription by RNA polymerase II  (IMP)
positive regulation of tumor necrosis factor production  (IGI)
protein kinase B signaling  (ISO)
regulation of behavior  (ISO)
regulation of cell shape  (IDA,ISO)
regulation of sensory perception of pain  (ISO)
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  (ISO)
response to cholesterol  (ISO)
response to drug  (ISO)
response to toxic substance  (ISO)
signaling  (ISO)
T cell chemotaxis  (ISO)

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
extracellular region  (IEA,ISO)
extracellular space  (IBA,IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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2. Chen J, etal., J Virol. 2010 Feb;84(3):1289-301. Epub 2009 Nov 11.
3. Codullo V, etal., Ann Rheum Dis. 2011 Jun;70(6):1115-21. Epub 2011 Feb 1.
4. Cook DN, etal., Science 1995 Sep 15;269(5230):1583-5.
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8. Glass WG, etal., J Immunol. 2004 Sep 15;173(6):4030-9. doi: 10.4049/jimmunol.173.6.4030.
9. Huang C, etal., Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
10. Iwata-Yoshikawa N, etal., J Virol. 2019 Mar 5;93(6). pii: JVI.01818-18. doi: 10.1128/JVI.01818-18. Print 2019 Mar 15.
11. Kaur J and Sanyal SN, Mol Carcinog. 2011 Jan 25. doi: 10.1002/mc.20736.
12. Keepers TR, etal., Infect Immun. 2007 Mar;75(3):1229-36. Epub 2007 Jan 12.
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16. MGD and Homologene mouse data transfer
17. MGD data from the GO Consortium
18. MGD IEA
19. Ni J, etal., Chin Med J (Engl). 2012 Mar;125(6):1147-52.
20. Nordoy I, etal., J Infect Dis. 1999 Jul;180(1):195-8.
21. OMIM Disease Annotation Pipeline
22. Peake JM, etal., Mol Nutr Food Res. 2011 Mar;55(3):400-10. doi: 10.1002/mnfr.201000195. Epub 2010 Oct 28.
23. Pipeline to import KEGG annotations from KEGG into RGD
24. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
25. Rachid MA, etal., Microbes Infect. 2006 Jul;8(8):2113-9. Epub 2006 Jun 6.
26. RGD automated import pipeline
27. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
28. RGD automated import pipeline for gene-chemical interactions
29. Shanley TP, etal., J Immunol 1995 May 1;154(9):4793-802.
30. Teramoto K, etal., J Pharmacol Sci. 2008 Jan;106(1):56-67. Epub 2008 Jan 11.
31. Turner JE, etal., J Immunol. 2008 Nov 1;181(9):6546-56.
32. Wang Y, etal., Int Immunopharmacol. 2006 Dec 5;6(12):1825-32. Epub 2006 Aug 31.
33. Wikman A, etal., Inflammation. 2008 Dec;31(6):384-90. doi: 10.1007/s10753-008-9089-8.
34. Wu Y, etal., J Immunol. 2008 Nov 1;181(9):6384-93.
35. Wu YP and Proia RL, Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8425-30. Epub 2004 May 20.
36. Yang Y, etal., J Allergy Clin Immunol. 2020 Apr 29. pii: S0091-6749(20)30576-5. doi: 10.1016/j.jaci.2020.04.027.
37. Yao Z, etal., Aging (Albany NY). 2020 May 2;12(9):7639-7651. doi: 10.18632/aging.103101. Epub 2020 May 2.
38. Zeng Y, etal., Biol Pharm Bull. 2007 Aug;30(8):1438-44.
39. Zhu XB, etal., Neuropathol Appl Neurobiol. 2012 Oct;38(6):602-16. doi: 10.1111/j.1365-2990.2012.01251.x.
Additional References at PubMed
PMID:1385544   PMID:1402664   PMID:1618855   PMID:1969921   PMID:1972563   PMID:2033269   PMID:2216738   PMID:2320111   PMID:2521353   PMID:2784565   PMID:3279154   PMID:3290382  
PMID:7542241   PMID:7594543   PMID:7594550   PMID:7601457   PMID:7636213   PMID:7779098   PMID:7789623   PMID:8097094   PMID:8292385   PMID:8299739   PMID:8413654   PMID:8496601  
PMID:8530103   PMID:8662890   PMID:8978677   PMID:9047380   PMID:9139699   PMID:9177770   PMID:9192769   PMID:9405404   PMID:9510207   PMID:9541500   PMID:9730682   PMID:9864144  
PMID:9990422   PMID:10049699   PMID:10094931   PMID:10235110   PMID:10349636   PMID:10397169   PMID:10415460   PMID:10438970   PMID:10553079   PMID:10565608   PMID:10594742   PMID:10749577  
PMID:10878389   PMID:10899907   PMID:10946298   PMID:10995569   PMID:11042159   PMID:11049973   PMID:11069716   PMID:11076861   PMID:11086082   PMID:11137111   PMID:11217851   PMID:11485904  
PMID:11509646   PMID:11553568   PMID:11553580   PMID:11756344   PMID:11875005   PMID:11972057   PMID:12080938   PMID:12085314   PMID:12098066   PMID:12126650   PMID:12163451   PMID:12176868  
PMID:12370381   PMID:12377948   PMID:12393512   PMID:12393595   PMID:12393677   PMID:12401480   PMID:12466851   PMID:12477932   PMID:12488501   PMID:12511416   PMID:12525571   PMID:12634360  
PMID:12645937   PMID:12649140   PMID:12850812   PMID:12960284   PMID:14581577   PMID:14761932   PMID:14978105   PMID:14981116   PMID:15059480   PMID:15223613   PMID:15316665   PMID:15368307  
PMID:15467013   PMID:15498767   PMID:15516494   PMID:15517609   PMID:15579460   PMID:15611273   PMID:15650768   PMID:15723811   PMID:15730850   PMID:15748167   PMID:15760677   PMID:15784598  
PMID:15790880   PMID:15829914   PMID:15831559   PMID:16009684   PMID:16105698   PMID:16141072   PMID:16141073   PMID:16284949   PMID:16288200   PMID:16299331   PMID:16397233   PMID:16517114  
PMID:16546096   PMID:16602821   PMID:16705092   PMID:16713992   PMID:16856209   PMID:16954498   PMID:17182592   PMID:17182684   PMID:17202339   PMID:17322370   PMID:17325167   PMID:17494633  
PMID:17525185   PMID:17549607   PMID:17588479   PMID:17698589   PMID:17949991   PMID:17979156   PMID:18077722   PMID:18227348   PMID:18375036   PMID:18485892   PMID:18508519   PMID:18535671  
PMID:18566004   PMID:18619972   PMID:18684972   PMID:18776949   PMID:19006696   PMID:19139201   PMID:19170716   PMID:19285486   PMID:19302485   PMID:19421418   PMID:19427874   PMID:19729478  
PMID:19853894   PMID:19893746   PMID:19897483   PMID:20042585   PMID:20046229   PMID:20053385   PMID:20083664   PMID:20100934   PMID:20124099   PMID:20140197   PMID:20164426   PMID:20195359  
PMID:20206135   PMID:20223588   PMID:20551286   PMID:20567093   PMID:20622889   PMID:20643506   PMID:20647543   PMID:20692319   PMID:20870892   PMID:20959807   PMID:21041732   PMID:21191075  
PMID:21267068   PMID:21308776   PMID:21317384   PMID:21488868   PMID:21784977   PMID:21873635   PMID:22007074   PMID:22037251   PMID:22359597   PMID:22451728   PMID:22493001   PMID:22528463  
PMID:22814670   PMID:22960654   PMID:23059626   PMID:23112334   PMID:23143790   PMID:23288165   PMID:23431040   PMID:23460747   PMID:23487425   PMID:23648818   PMID:23799074   PMID:24080631  
PMID:24135048   PMID:24166712   PMID:24367031   PMID:24370436   PMID:24413563   PMID:24510316   PMID:24625974   PMID:24639355   PMID:24989845   PMID:25049356   PMID:25092803   PMID:25153123  
PMID:25595646   PMID:25663168   PMID:25762141   PMID:25847238   PMID:25893677   PMID:25895671   PMID:26056232   PMID:26472813   PMID:26511387   PMID:26663750   PMID:26671708   PMID:26743624  
PMID:26854929   PMID:27006388   PMID:27022143   PMID:27109512   PMID:27146354   PMID:27230858   PMID:27318131   PMID:27799249   PMID:27879269   PMID:28041977   PMID:28096401   PMID:28711238  
PMID:28751523   PMID:28847849   PMID:29402784   PMID:29550827   PMID:30199766   PMID:30271404   PMID:30279500   PMID:30321562   PMID:30510188   PMID:31508417   PMID:32296175  


Genomics

Comparative Map Data
Ccl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,538,669 - 83,540,204 (-)NCBIGRCm39mm39
GRCm39 Ensembl1183,538,670 - 83,540,181 (-)Ensembl
GRCm381183,647,843 - 83,649,378 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,647,844 - 83,649,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,461,345 - 83,462,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv361183,464,040 - 83,465,552 (-)NCBImm8
Celera1193,252,227 - 93,253,762 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.04NCBI
CCL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1736,088,256 - 36,090,169 (-)EnsemblGRCh38hg38GRCh38
GRCh381736,088,256 - 36,090,143 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371734,415,602 - 34,417,489 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361731,439,715 - 31,441,619 (-)NCBINCBI36hg18NCBI36
Build 341731,439,717 - 31,441,600NCBI
Celera1731,325,155 - 31,327,059 (-)NCBI
Cytogenetic Map17q12NCBI
HuRef1730,600,149 - 30,602,053 (-)NCBIHuRef
CHM1_11734,479,827 - 34,481,731 (-)NCBICHM1_1
Ccl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21068,451,388 - 68,452,938 (-)NCBI
Rnor_6.0 Ensembl1070,869,513 - 70,871,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01070,869,516 - 70,871,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01070,501,119 - 70,502,669 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,744,559 - 71,746,109 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,758,928 - 71,760,479 (-)NCBI
Celera1067,390,853 - 67,392,403 (-)NCBICelera
Cytogenetic Map10q26NCBI
CCL3L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,491,885 - 39,493,370 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,491,999 - 39,493,345 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,061,465 - 41,062,811 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103242767
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11629,887,799 - 29,897,664 (+)NCBI

Position Markers
Ccl3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,648,257 - 83,649,227UniSTSGRCm38
MGSCv371183,461,759 - 83,462,729UniSTSGRCm37
Celera1193,252,641 - 93,253,611UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.59UniSTS
AI323804  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,648,111 - 83,648,207UniSTSGRCm38
MGSCv371183,461,613 - 83,461,709UniSTSGRCm37
Celera1193,252,495 - 93,252,591UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.59UniSTS
Whitehead/MRC_RH111071.89UniSTS
M23447  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,648,130 - 83,648,263UniSTSGRCm38
MGSCv371183,461,632 - 83,461,765UniSTSGRCm37
Celera1193,252,514 - 93,252,647UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.59UniSTS
Whitehead/MRC_RH111071.89UniSTS
D11Dcr14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,650,643 - 83,650,798UniSTSGRCm38
MGSCv371183,464,145 - 83,464,300UniSTSGRCm37
Celera1193,255,031 - 93,255,186UniSTS
Cytogenetic Map11CUniSTS
cM Map11 UniSTS
PMC98533P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,648,619 - 83,649,243UniSTSGRCm38
MGSCv371183,462,121 - 83,462,745UniSTSGRCm37
Celera1193,253,003 - 93,253,627UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.59UniSTS
UniSTS:489164  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,648,118 - 83,649,305UniSTSGRCm38
MGSCv371183,461,620 - 83,462,807UniSTSGRCm37
Celera1193,252,502 - 93,253,689UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.59UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:117
Interacting mature miRNAs:120
Transcripts:ENSMUST00000001008
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA895994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC111443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX524012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU366956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG515534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X12531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000001008   ⟹   ENSMUSP00000001008
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1183,647,844 - 83,649,355 (-)Ensembl
RefSeq Acc Id: NM_011337   ⟹   NP_035467
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,538,669 - 83,540,204 (-)NCBI
GRCm381183,647,843 - 83,649,378 (-)ENTREZGENE
MGSCv371183,461,345 - 83,462,880 (-)RGD
Celera1193,252,227 - 93,253,762 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035467   ⟸   NM_011337
- Peptide Label: precursor
- UniProtKB: P10855 (UniProtKB/Swiss-Prot),   Q5QNW0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000001008   ⟸   ENSMUST00000001008
Protein Domains
SCY

Promoters
RGD ID:6820609
Promoter ID:MM_KWN:8907
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:NM_011337,   UC007KPO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361183,461,356 - 83,462,772 (-)MPROMDB
RGD ID:8675918
Promoter ID:EPDNEW_M15990
Type:initiation region
Name:Ccl3_1
Description:Mus musculus chemokine (C-C motif) ligand 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381183,649,357 - 83,649,417EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98260 AgrOrtholog
Ensembl Genes ENSMUSG00000000982 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000001008 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000001008 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98260 ENTREZGENE
NCBI Gene 20302 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccl3 PhenoGen
PROSITE SMALL_CYTOKINES_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CCL3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U6F9_MOUSE UniProtKB/TrEMBL
  Q5QNW0 ENTREZGENE, UniProtKB/TrEMBL
  V6AW11_MOUSE UniProtKB/TrEMBL
UniProt Secondary P14096 UniProtKB/Swiss-Prot