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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of FGD5 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of FGD5 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RGD:1313708 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of FGD5 mRNA | CTD | PMID:20404318 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGD5 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1305589 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGD5 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGD5 mRNA | CTD | PMID:23994337 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23994337 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of FGD5 mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of FGD5 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bis4-hydroxyphenylsulfone results in increased expression of FGD5 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of FGD5 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:1313708 | 6480464 | Decitabine affects the expression of FGD5 mRNA | CTD | PMID:23300844 | aflatoxin B1 | decreases methylation | ISO | RGD:1313708 | 6480464 | Aflatoxin B1 results in decreased methylation of FGD5 exon | CTD | PMID:30157460 | aflatoxin B1 | decreases expression | ISO | RGD:1313708 | 6480464 | Aflatoxin B1 results in decreased expression of FGD5 mRNA | CTD | PMID:32234424 | aflatoxin B2 | increases methylation | ISO | RGD:1313708 | 6480464 | aflatoxin B2 results in increased methylation of FGD5 exon | CTD | PMID:30157460 | amiodarone | increases expression | ISO | RGD:1313708 | 6480464 | Amiodarone results in increased expression of FGD5 mRNA | CTD | PMID:19774075 | benzo[a]pyrene | increases mutagenesis | ISO | RGD:1313708 | 6480464 | Benzoapyrene results in increased mutagenesis of FGD5 gene | CTD | PMID:25435355 | benzo[a]pyrene | decreases expression | ISO | RGD:1313708 | 6480464 | Benzoapyrene results in decreased expression of FGD5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1313708 | 6480464 | Benzoapyrene affects the methylation of FGD5 intron, Benzoapyrene affects the methylation of FGD5 promoter | CTD | PMID:27901495, PMID:30157460 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzoapyrene results in decreased expression of FGD5 mRNA | CTD | PMID:27195522 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzoapyrene results in increased expression of FGD5 mRNA | CTD | PMID:22228805, PMID:32417428 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzobfluoranthene results in increased expression of FGD5 mRNA | CTD | PMID:26377693 | benzo[e]pyrene | increases methylation | ISO | RGD:1313708 | 6480464 | benzoepyrene results in increased methylation of FGD5 exon, benzoepyrene results in increased methylation of FGD5 intron | CTD | PMID:30157460 | beta-naphthoflavone | increases expression | EXP | | 6480464 | beta-Naphthoflavone results in increased expression of FGD5 mRNA | CTD | PMID:23994337 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FGD5 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FGD5 mRNA | CTD | PMID:30951980 | bisphenol A | decreases expression | ISO | RGD:1305589 | 6480464 | bisphenol A results in decreased expression of FGD5 mRNA | CTD | PMID:30816183 | bisphenol A | affects expression | ISO | RGD:1305589 | 6480464 | bisphenol A affects the expression of FGD5 mRNA | CTD | PMID:25181051 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of FGD5 mRNA | CTD | PMID:30951980 | cisplatin | affects expression | ISO | RGD:1313708 | 6480464 | Cisplatin affects the expression of FGD5 mRNA | CTD | PMID:23300844 | cobalt dichloride | decreases expression | ISO | RGD:1313708 | 6480464 | cobaltous chloride results in decreased expression of FGD5 mRNA | CTD | PMID:19320972 | cocaine | increases expression | ISO | RGD:1305589 | 6480464 | Cocaine results in increased expression of FGD5 mRNA | CTD | PMID:17898221 | cyclosporin A | decreases expression | ISO | RGD:1313708 | 6480464 | Cyclosporine results in decreased expression of FGD5 mRNA | CTD | PMID:27989131 | dorsomorphin | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | entinostat | increases expression | ISO | RGD:1313708 | 6480464 | entinostat results in increased expression of FGD5 mRNA | CTD | PMID:26272509, PMID:27188386 | entinostat | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of FGD5 mRNA | CTD | PMID:27188386 | methapyrilene | increases methylation | ISO | RGD:1313708 | 6480464 | Methapyrilene results in increased methylation of FGD5 exon, Methapyrilene results in increased methylation of FGD5 intron | CTD | PMID:30157460 | N-Nitrosopyrrolidine | decreases expression | ISO | RGD:1313708 | 6480464 | N-Nitrosopyrrolidine results in decreased expression of FGD5 mRNA | CTD | PMID:32234424 | nickel atom | decreases expression | ISO | RGD:1313708 | 6480464 | Nickel results in decreased expression of FGD5 mRNA | CTD | PMID:25583101 | O-methyleugenol | decreases expression | ISO | RGD:1313708 | 6480464 | methyleugenol results in decreased expression of FGD5 mRNA | CTD | PMID:32234424 | orphenadrine | affects expression | ISO | RGD:1305589 | 6480464 | Orphenadrine affects the expression of FGD5 mRNA | CTD | PMID:23665939 | panobinostat | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of FGD5 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:1313708 | 6480464 | panobinostat results in increased expression of FGD5 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of FGD5 mRNA | CTD | PMID:27188386 | SB 431542 | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | Soman | decreases expression | ISO | RGD:1305589 | 6480464 | Soman results in decreased expression of FGD5 mRNA | CTD | PMID:19281266 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of FGD5 mRNA | CTD | PMID:23557971 | toluene | increases expression | ISO | RGD:1305589 | 6480464 | Toluene results in increased expression of FGD5 mRNA | CTD | PMID:22967744 | trichostatin A | increases expression | ISO | RGD:1313708 | 6480464 | trichostatin A results in increased expression of FGD5 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of FGD5 mRNA | CTD | PMID:27188386 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of FGD5 mRNA | CTD | PMID:28973697 | valproic acid | increases methylation | ISO | RGD:1313708 | 6480464 | Valproic Acid results in increased methylation of FGD5 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1313708 | 6480464 | Valproic Acid results in increased expression of FGD5 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | RGD:1313708 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of FGD5 mRNA | CTD | PMID:27188386 | valproic acid | affects expression | ISO | RGD:1313708 | 6480464 | Valproic Acid affects the expression of FGD5 mRNA | CTD | PMID:25979313 | vinclozolin | affects expression | ISO | RGD:1305589 | 6480464 | vinclozolin affects the expression of FGD5 mRNA | CTD | PMID:19015723 | |