Mmp2 (matrix metallopeptidase 2) - Rat Genome Database

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Gene: Mmp2 (matrix metallopeptidase 2) Mus musculus
Symbol: Mmp2
Name: matrix metallopeptidase 2
RGD ID: 730822
Description: Enables metalloendopeptidase activity. Involved in response to amyloid-beta. Acts upstream of or within several processes, including blood vessel maturation; bone trabecula formation; and collagen catabolic process. Located in several cellular components, including extracellular space; mitochondrion; and sarcomere. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart; jaw; and musculoskeletal system. Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 72 kDa gelatinase; 72 kDa type IV collagenase; 72kD gelatinase; 72kD type IV collagenase; 72kDa gelatinase; 72kDa type IV collagenase; Clg; Clg4a; Ge; GelA; gelatinase A; matrix metalloproteinase 2; matrix metalloproteinase-2; MMP-; MMP-2
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39893,553,920 - 93,580,049 (+)NCBIGRCm39mm39
GRCm39 Ensembl893,553,919 - 93,580,048 (+)Ensembl
GRCm38892,827,290 - 92,853,421 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl892,827,291 - 92,853,420 (+)EnsemblGRCm38mm10GRCm38
MGSCv37895,351,227 - 95,377,319 (+)NCBIGRCm37mm9NCBIm37
MGSCv36895,716,456 - 95,742,548 (+)NCBImm8
Celera897,157,107 - 97,183,318 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map844.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Lung Injury  (ISO)
acute necrotizing pancreatitis  (ISO)
Acute Otitis Media  (IEP)
adrenoleukodystrophy  (ISO)
alcohol use disorder  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (IEP,ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
aortic disease  (ISO)
Aortic Rupture  (ISO)
aortic valve disease 2  (ISO)
arteriosclerosis  (ISO)
Arteriovenous Fistula  (IDA,ISO)
atherosclerosis  (IDA,ISO)
atrial fibrillation  (ISO)
Behcet's disease  (ISO)
bone disease  (ISO)
Bone Neoplasms  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
carotid artery disease  (ISO)
Carotid Artery Injuries  (ISO)
carotid stenosis  (IEP)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chlamydophila Infections  (ISO)
cholangiocarcinoma  (ISO)
cholestasis  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (IDA,ISO)
Chronic Periodontitis  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
conjunctivitis  (ISO)
Craniofacial Abnormalities  (ISO)
cutaneous leishmaniasis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
dilated cardiomyopathy  (IDA)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
Embolism  (ISO)
end stage renal disease  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
extrahepatic cholestasis  (ISO)
Fetal Growth Retardation  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (ISO)
Gallbladder Neoplasms  (ISO)
gastric ulcer  (ISO)
glioblastoma  (ISO)
Gouty Arthritis  (ISO)
Graft Occlusion, Vascular  (IEP)
head and neck squamous cell carcinoma  (ISO)
heart valve disease  (ISO)
hemangioma  (ISO)
hepatocellular carcinoma  (ISO)
Herpes Simplex Encephalitis  (IDA)
high grade glioma  (ISO)
Hydatidiform Mole  (ISO)
Hyperoxia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
immunoglobulin light chain amyloidosis  (ISO)
Inflammation  (ISO)
intracranial aneurysm  (ISO)
ischemia  (IDA)
keratoconus  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (ISO)
leiomyoma  (ISO)
liver cirrhosis  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
Malignant Pleural Effusions  (ISO)
Mammary Neoplasms, Experimental  (IDA,ISO)
Mandibular Diseases  (ISO)
Marfan syndrome  (IEP,ISO)
Maxillary Diseases  (ISO)
Metabolic Bone Diseases  (ISO)
Multiple Organ Failure  (IEP)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
myocarditis  (IDA)
myopia  (ISO)
Nasal Polyps  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neointima  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Nephrogenic Fibrosing Dermopathy  (ISO)
Nose Neoplasms  (ISO)
ocular hypertension  (ISO)
Oral Lichen Planus  (ISO)
oral submucous fibrosis  (ISO)
osteoarthritis  (ISO)
Osteolysis  (ISO)
Osteolysis Hereditary Multicentric  (ISO)
osteonecrosis  (ISO)
osteosarcoma  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
papilloma  (IEP)
paracoccidioidomycosis  (IDA)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (ISO)
Pneumococcal Meningitis  (ISO)
polycystic ovary syndrome  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (ISO)
prostate cancer  (ISO)
pseudoxanthoma elasticum  (ISO)
pterygium  (ISO)
pulmonary embolism  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
Puromycin Aminonucleoside Nephrosis  (ISO)
pyoderma gangrenosum  (ISO)
renal cell carcinoma  (ISO)
renal hypertension  (ISO)
respiratory syncytial virus infectious disease  (IEP)
retinal vein occlusion  (ISO)
rheumatoid arthritis  (ISO)
Right Ventricular Hypertrophy  (ISO)
Sepsis  (ISO)
skin melanoma  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
stomach carcinoma  (ISO)
Stroke  (ISO)
Sturge-Weber syndrome  (ISO)
Subarachnoid Hemorrhage  (ISO)
Sweet syndrome  (ISO)
temporal arteritis  (ISO)
Testicular Germ Cell Tumor  (ISO)
thoracic aortic aneurysm  (IDA,ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
tropical spastic paraparesis  (ISO)
type 2 diabetes mellitus  (ISO)
Ulcer  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
vascular dementia  (ISO)
Venous Thrombosis  (ISO)
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(20S)-ginsenoside Rg3  (ISO)
(R)-lipoic acid  (ISO)
(R)-noradrenaline  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4,6-trinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dihydroxybenzoic acid  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (EXP)
2-deoxy-D-glucose  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3-hydroxypicolinic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
3-Nitrobenzanthrone  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-Nerolidylcatechol  (ISO)
5,6alpha-epoxy-5alpha-cholestan-3beta-ol  (ISO)
5-aminolevulinic acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
7-ketocholesterol  (ISO)
9,10-phenanthroquinone  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP,ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ageladine A  (ISO)
AICA ribonucleotide  (ISO)
alachlor  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-D-galactose  (ISO)
alpha-mangostin  (ISO)
alpha-naphthoflavone  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
AM-251  (ISO)
ambroxol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
anagliptin  (ISO)
andrographolide  (EXP)
anethole  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (ISO)
apigenin  (ISO)
arachidonic acid  (ISO)
arecoline  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
astemizole  (ISO)
atorvastatin calcium  (EXP,ISO)
azoxystrobin  (ISO)
Bacoside a  (ISO)
baicalein  (EXP,ISO)
beclomethasone  (ISO)
benazepril  (ISO)
benomyl  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
betulin  (ISO)
betulinic acid  (EXP,ISO)
bicalutamide  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP,ISO)
boric acid  (EXP)
brazilein  (ISO)
brucine  (EXP,ISO)
bucladesine  (ISO)
bufalin  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (ISO)
calcium dichloride  (EXP,ISO)
cantharidin  (ISO)
capecitabine  (ISO)
capsaicin  (ISO)
carbendazim  (ISO)
carbon nanotube  (EXP)
carfilzomib  (ISO)
carvedilol  (ISO)
casticin  (EXP,ISO)
celastrol  (ISO)
celecoxib  (ISO)
CGS-21680  (ISO)
Chebulagic acid  (ISO)
chenodeoxycholic acid  (EXP)
chitosan  (ISO)
chlordecone  (EXP)
chloroquine  (ISO)
chlorpyrifos  (ISO)
choline  (EXP,ISO)
chromium atom  (ISO)
chromium(6+)  (EXP)
chrysin  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
coenzyme Q10  (ISO)
columbamine  (ISO)
conjugated linoleic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP,ISO)
cucurbitacin B  (EXP)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
deguelin  (ISO)
demethoxycurcumin  (ISO)
desferrioxamine B  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (ISO)
dieckol  (ISO)
diethyl maleate  (ISO)
dihydroartemisinin  (ISO)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinous acid  (ISO)
diosgenin  (ISO)
dioxygen  (EXP,ISO)
disodium cromoglycate  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
diuron  (ISO)
divanadium pentaoxide  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (EXP,ISO)
EC (phospholipase A2) inhibitor  (ISO)
EC (peptidyl-dipeptidase A) inhibitor  (ISO)
edaravone  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
embelin  (ISO)
emetine  (ISO)
entinostat  (EXP,ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
eugenol  (ISO)
excitatory amino acid agonist  (EXP)
farrerol  (ISO)
fenofibrate  (ISO)
ferric oxide  (EXP)
ferrichrome  (ISO)
Fexofenadine hydrochloride  (ISO)
fisetin  (EXP,ISO)
flavonol  (ISO)
fluvastatin  (ISO)
folic acid  (EXP,ISO)
fosinopril  (EXP)
fructose  (EXP)
fucoidan  (ISO)
fulvestrant  (ISO)
furan  (ISO)
galactose  (ISO)
gallic acid  (ISO)
Genipin  (ISO)
Geniposide pentaacetate  (ISO)
genistein  (ISO)
Geraniin  (ISO)
gingerol  (ISO)
Ginkgoic acid  (ISO)
ginsenoside Rg1  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
Gly-His-Lys  (ISO)
glycidol  (ISO)
glycyrrhizinic acid  (EXP)
graphene oxide  (EXP)
graphite  (ISO)
heparin  (ISO)
Hexachloro-1,3-butadiene  (ISO)
hexachlorobenzene  (ISO)
hexadecanoic acid  (ISO)
hinokiflavone  (EXP,ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
ibuprofen  (ISO)
ICI 118551  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indinavir  (ISO)
indometacin  (EXP,ISO)
irigenin  (ISO)
iron trichloride  (ISO)
isoliquiritigenin  (ISO)
isoprenaline  (EXP,ISO)
isotretinoin  (ISO)
juglone  (ISO)
kaempferol  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-cysteine  (ISO)
L-methionine  (EXP)
lasofoxifene  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
letrozole  (ISO)
leuprolide  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lisinopril dihydrate  (ISO)
lithocholic acid  (EXP,ISO)
losartan  (EXP,ISO)
lovastatin  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
mannuronic acid  (ISO)
marimastat  (ISO)
medroxyprogesterone acetate  (EXP,ISO)
melatonin  (EXP,ISO)
melittin  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methamphetamine  (EXP)
Methanandamide  (ISO)
methotrexate  (ISO)
methyl caffeate  (ISO)
methylcobalamin  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
metoprolol  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (ISO)
minocycline  (EXP,ISO)
miquelianin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (EXP,ISO)
morin  (ISO)
morusin  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
naproxen  (ISO)
naringin  (ISO)
Neferine  (ISO)
nerolidol  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicotine  (EXP,ISO)
nitric oxide  (ISO)
nitroglycerin  (ISO)
Nonylphenol  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (EXP)
oleanolic acid  (ISO)
oleic acid  (ISO)
omeprazole  (ISO)
oridonin  (ISO)
oroxylin A  (ISO)
osthole  (ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
oxytocin  (ISO)
ozone  (EXP,ISO)
p-cresol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (ISO)
pentachlorophenol  (EXP)
pentanal  (ISO)
pentane-2,3-dione  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perindopril  (EXP,ISO)
phenanthrolines  (ISO)
phenethyl caffeate  (ISO)
phenylarsine oxide  (ISO)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidic acid  (ISO)
phosphatidylcholine  (ISO)
picoxystrobin  (ISO)
picropodophyllotoxin  (ISO)
piperine  (ISO)
pipoxolan  (ISO)
pirfenidone  (ISO)
piroxicam  (EXP)
platycodin D  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
pravastatin  (ISO)
prazosin  (ISO)
prednisolone  (ISO)
prinomastat  (ISO)
probucol  (ISO)
progesterone  (ISO)
propanal  (ISO)
propranolol  (ISO)
prostaglandin E2  (ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (ISO)
protoporphyrin  (ISO)
pterostilbene  (EXP)
puerarin  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
radon atom  (ISO)
radon(0)  (ISO)
raloxifene  (ISO)
ramipril  (ISO)
razoxane  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (EXP)
rhodotorulic acid  (ISO)
rosmarinic acid  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
rutin  (EXP,ISO)
S-adenosyl-L-homocysteine  (EXP,ISO)
S-allylcysteine  (ISO)
Salinomycin  (ISO)
Salvianolic acid A  (ISO)
sanguinarine  (ISO)
saxagliptin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
selumetinib  (ISO)
serpentine asbestos  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
solasodine  (ISO)
Sophoricoside  (EXP)
sorafenib  (EXP)
sphingosine 1-phosphate  (ISO)
squalene  (ISO)
streptozocin  (EXP,ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
Tanshinone I  (ISO)
taurocholic acid  (ISO)
tebuconazole  (ISO)
telmisartan  (ISO)
temozolomide  (ISO)
terazosin  (ISO)
terbinafine  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetrahydrocurcumin  (EXP)
tetraphene  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP,ISO)
thymoquinone  (ISO)
titanium atom  (ISO)
titanium dioxide  (EXP)
tolfenamic acid  (ISO)
tomatidine  (ISO)
Tomentosin  (ISO)
topotecan  (ISO)
trans-anethole  (ISO)
trans-cinnamic acid  (EXP)
trans-rhaponticin  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triciribine  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
troglitazone  (EXP,ISO)
tropisetron  (ISO)
tyrphostin AG 1478  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
ursolic acid  (ISO)
Ursonic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WIN 55212-2  (ISO)
withaferin A  (ISO)
wogonin  (ISO)
wortmannin  (ISO)
Y-27632  (ISO)
zafirlukast  (ISO)
zearalenone  (ISO)
zerumbone  (ISO)
zidovudine  (ISO)
zinc atom  (EXP)
zinc dichloride  (ISO)
zinc protoporphyrin  (EXP,ISO)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis  (IEA,ISO)
blood vessel maturation  (IGI)
bone trabecula formation  (IGI)
cell migration  (ISO)
cellular response to amino acid stimulus  (IDA)
cellular response to cytokine stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to fluid shear stress  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to reactive oxygen species  (IMP)
cellular response to UV-A  (ISO)
collagen catabolic process  (IBA,IMP,ISO)
embryo implantation  (IDA)
endodermal cell differentiation  (ISO)
extracellular matrix organization  (IBA)
face morphogenesis  (IGI)
female pregnancy  (ISO)
heart development  (ISO)
intramembranous ossification  (IGI)
luteinization  (ISO)
negative regulation of cell adhesion  (ISO)
negative regulation of vasoconstriction  (ISO)
ovarian follicle development  (ISO)
ovulation from ovarian follicle  (ISO)
parturition  (ISO)
peripheral nervous system axon regeneration  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of innate immune response  (IDA)
positive regulation of smooth muscle cell proliferation  (IMP)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
prostate gland epithelium morphogenesis  (ISO)
protein catabolic process  (ISO)
proteolysis  (IBA,ISO)
response to activity  (ISO)
response to amyloid-beta  (IDA)
response to cytokine  (ISO)
response to electrical stimulus  (ISO)
response to estrogen  (ISO)
response to hydrogen peroxide  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (IBA,IDA,ISO)
response to mechanical stimulus  (ISO)
response to nicotine  (ISO)
response to oxidative stress  (ISO)
response to radiation  (ISO)
response to retinoic acid  (ISO)
response to xenobiotic stimulus  (ISO)
skeletal system morphogenesis  (IGI)
tissue remodeling  (IBA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal aorta morphology  (IAGP)
abnormal angiogenesis  (IAGP)
abnormal aorta wall morphology  (IAGP)
abnormal articular cartilage morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IEA)
abnormal cardiovascular system physiology  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal coronal suture morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal heart morphology  (IEA)
abnormal induced retinal neovascularization  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lambdoid suture morphology  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal response to cardiac infarction  (IAGP)
abnormal sagittal suture morphology  (IAGP)
abnormal seminal vesicle morphology  (IEA)
abnormal skeletal muscle morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal spleen morphology  (IEA)
abnormal stomach morphology  (IEA)
abnormal trabecular bone morphology  (IAGP)
abnormal vascular smooth muscle physiology  (IAGP)
aortitis  (IAGP)
arthritis  (IAGP)
brain inflammation  (IAGP)
broad snout  (IAGP)
cataract  (IEA)
coronal suture sclerosis  (IAGP)
cyanosis  (IAGP)
decreased angiogenesis  (IAGP)
decreased birth weight  (IAGP)
decreased body length  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IAGP)
decreased bone volume  (IAGP)
decreased inflammatory response  (IAGP)
decreased length of long bones  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased prepulse inhibition  (IEA)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to induced choroidal neovascularization  (IAGP)
decreased tumor growth/size  (IAGP)
delayed muscle development  (IAGP)
dilated heart left ventricle  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged heart  (IEA)
enlarged lymph nodes  (IEA)
enlarged spleen  (IEA)
enlarged stomach  (IEA)
impaired lung alveolus development  (IAGP)
increased inner canthal distance  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
increased susceptibility to induced aneurysm formation  (IAGP)
lambdoid suture sclerosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
sagittal suture sclerosis  (IAGP)
short mandible  (IAGP)
short maxilla  (IAGP)
short snout  (IAGP)
small kidney  (IEA)
thin diaphragm muscle  (IAGP)

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