Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Timp1 (tissue inhibitor of metalloproteinase 1) Mus musculus
Analyze
Symbol: Timp1
Name: tissue inhibitor of metalloproteinase 1
Description: Predicted to have molecular function regulator; protease binding activity; and zinc ion binding activity. Involved in connective tissue replacement involved in inflammatory response wound healing. Localizes to the basement membrane. Is expressed in several structures, including early conceptus; femur cartilage condensation; jaw; reproductive system; and skeletal system. Orthologous to human TIMP1 (TIMP metallopeptidase inhibitor 1); PARTICIPATES IN interleukin-6 signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Clgi; collagenase inhibitor 16C8 fibroblast; EPA; erythroid-potentiating activity; metalloproteinase inhibitor 1; MGC7143; Timp; TIMP-1; tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1
Orthologs:
Homo sapiens (human) : TIMP1 (TIMP metallopeptidase inhibitor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Timp1 (TIMP metallopeptidase inhibitor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Timp1 (TIMP metallopeptidase inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TIMP1 (TIMP metallopeptidase inhibitor 1)
Canis lupus familiaris (dog) : TIMP1 (TIMP metallopeptidase inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Timp1 (TIMP metallopeptidase inhibitor 1)
Sus scrofa (pig) : TIMP1 (TIMP metallopeptidase inhibitor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 EnsemblX20,870,166 - 20,874,735 (+)Ensembl
GRCm38X20,870,166 - 20,874,737 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X20,447,292 - 20,451,863 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X20,027,998 - 20,031,591 (+)NCBImm8
CeleraX19,001,307 - 19,005,878 (+)NCBICelera
Cytogenetic MapX A1.3NCBI
cM MapX16.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Timp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731433
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.