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Gene: Sema6b (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B) Mus musculus
Symbol: Sema6b
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Description: Exhibits semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to the extracellular space and integral component of plasma membrane. Is expressed in several structures, including genitourinary system; liver; musculature; spinal cord; and spleen. Orthologous to human SEMA6B (semaphorin 6B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC143995; MGC143996; Sema; sema N; sema VIB; Seman; semaphorin VIB; semaphorin-6B; semaphorin-N; semaZ; VIb
Homo sapiens (human) : SEMA6B (semaphorin 6B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sema6b (semaphorin 6B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema6b (semaphorin 6B)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA6B (semaphorin 6B)
Canis lupus familiaris (dog) : SEMA6B (semaphorin 6B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sema6b (semaphorin 6B)
Sus scrofa (pig) : SEMA6B (semaphorin 6B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381756,123,085 - 56,140,343 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371756,262,508 - 56,279,766 (-)NCBIGRCm37mm9NCBIm37
MGSCv361755,716,378 - 55,726,158 (-)NCBImm8
Celera1759,541,746 - 59,547,130 (-)NCBICelera
Cytogenetic Map17 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sema6b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736203
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.