Nr1h4 (nuclear receptor subfamily 1, group H, member 4) - Rat Genome Database

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Gene: Nr1h4 (nuclear receptor subfamily 1, group H, member 4) Mus musculus
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Symbol: Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
RGD ID: 734104
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; bile acid binding activity; and retinoid X receptor binding activity. Involved in several processes, including lipid homeostasis; negative regulation of cytokine production; and regulation of signal transduction. Acts upstream of or within several processes, including Notch signaling pathway; bile acid metabolic process; and negative regulation of very-low-density lipoprotein particle remodeling. Predicted to be located in euchromatin and nucleus. Predicted to be part of receptor complex. Is expressed in several structures, including 1st branchial arch; central nervous system; liver; sensory organ; and urinary system. Used to study hepatocellular carcinoma. Human ortholog(s) of this gene implicated in extrahepatic cholestasis; hepatocellular carcinoma; and progressive familial intrahepatic cholestasis 5. Orthologous to human NR1H4 (nuclear receptor subfamily 1 group H member 4); PARTICIPATES IN bile acid signaling pathway; bile acid signaling pathway; bile acid transport pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI957360; bile acid receptor; farnesoid X activated receptor; farnesoid X-activated receptor; farnesol receptor HRR-1; FX; Fxr; HR; HRR1; nuclear receptor subfamily 1 group H member 4; retinoid X receptor-interacting protein 14; RI; RIP14; Rxr; RXR-interacting protein 14; Rxrip14
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,290,096 - 89,369,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1089,290,096 - 89,369,447 (-)Ensembl
GRCm381089,454,234 - 89,533,645 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,454,234 - 89,533,585 (-)EnsemblGRCm38mm10GRCm38
MGSCv371088,916,979 - 88,996,367 (-)NCBIGRCm37mm9NCBIm37
MGSCv361088,884,177 - 88,936,426 (-)NCBImm8
Celera1091,441,224 - 91,574,747 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1044.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
22,23-dihydroavermectin B1a  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,6-diaminoacridine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (EXP)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
9-aminoacridine  (ISO)
abamectin  (ISO)
acadesine  (EXP,ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
albendazole  (ISO)
albendazole S-oxide  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
alpha-linolenic acid  (ISO)
alvocidib  (ISO)
ammonium chloride  (ISO)
angelicin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apigenin  (ISO)
arachidonic acid  (ISO)
arjunolic acid  (ISO)
arotinoid acid  (ISO)
arsenite(3-)  (EXP)
atazanavir sulfate  (ISO)
benazepril  (ISO)
benidipine  (ISO)
benomyl  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
beta-hexachlorocyclohexane  (EXP,ISO)
beta-naphthoflavone  (ISO)
bezafibrate  (EXP,ISO)
bifenthrin  (ISO)
biochanin A  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Boldine  (ISO)
bortezomib  (ISO)
bosentan  (ISO)
butachlor  (ISO)
butanal  (ISO)
carbendazim  (ISO)
carbon nanotube  (EXP)
chenodeoxycholic acid  (EXP,ISO)
chlorpromazine  (ISO)
cholanic acid  (ISO)
cholate  (ISO)
cholesterol  (EXP,ISO)
cholic acid  (EXP,ISO)
chrysin  (ISO)
ciclobendazole  (ISO)
cilnidipine  (ISO)
cisplatin  (ISO)
citric acid  (EXP)
clevidipine  (ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corilagin  (ISO)
Cyclopamine  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
daunorubicin  (ISO)
DDE  (ISO)
deoxycholic acid  (EXP,ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
digoxin  (ISO)
dihydroartemisinin  (ISO)
dimethyl sulfoxide  (ISO)
Diosbulbin B  (EXP)
dioscin  (ISO)
diosgenin  (ISO)
Diphenadione  (ISO)
dipyridamole  (ISO)
dobutamine  (ISO)
Doramectin  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emamectin  (ISO)
emetine  (ISO)
emodin  (EXP)
endosulfan  (ISO)
enilconazole  (EXP)
eprinomectin  (ISO)
ethacridine  (ISO)
ethanol  (EXP,ISO)
ethylestrenol  (ISO)
farnesol  (ISO)
felodipine  (ISO)
fenbendazole  (ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
Fexaramine  (ISO)
flucythrinate  (ISO)
fluoranthene  (EXP)
fluoxastrobin  (ISO)
fluvalinate  (ISO)
fulvestrant  (EXP,ISO)
furan  (EXP,ISO)
gallocatechin  (ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
Gentiopicrin  (ISO)
ginsenoside Rg1  (ISO)
glafenine  (ISO)
glyburide  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinic acid  (ISO)
griseofulvin  (ISO)
guggulsterone  (EXP,ISO)
GW 3965  (EXP)
GW 4064  (EXP,ISO)
GW 7647  (ISO)
hexadecanoic acid  (EXP,ISO)
high-density lipoprotein cholesterol  (EXP)
hydrogen peroxide  (ISO)
ibuprofen  (EXP)
idarubicin  (ISO)
imazamox  (ISO)
imazapyr  (ISO)
Imazethapyr  (ISO)
isoniazide  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
Isradipine  (ISO)
ivermectin  (EXP,ISO)
juvenile hormone III  (ISO)
kadethrin  (ISO)
ketoconazole  (ISO)
lacidipine  (ISO)
lercanidipine  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP,ISO)
malic acid  (EXP)
manidipine  (ISO)
mebendazole  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  (ISO)
methylmercury chloride  (ISO)
milbemycin  (ISO)
mitomycin C  (ISO)
monascin  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
montelukast  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalenes  (ISO)
nefazodone  (ISO)
nemorubicin  (ISO)
Nicardipine  (ISO)
nifedipine  (ISO)
nimesulide  (ISO)
nimodipine  (ISO)
nisoldipine  (ISO)
nitrendipine  (ISO)
nitrofen  (ISO)
nocodazole  (ISO)
obeticholic acid  (EXP,ISO)
oleanolic acid  (EXP)
oleic acid  (ISO)
oxfendazole  (ISO)
ozone  (EXP)
papaverine  (ISO)
paracetamol  (EXP,ISO)
pentamidine  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl caffeate  (EXP)
phenobarbital  (EXP)
phenothrin  (ISO)
picoxystrobin  (ISO)
picropodophyllotoxin  (ISO)
Pirarubicin  (ISO)
pirinixic acid  (EXP)
platycodin D  (ISO)
podophyllotoxin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
psoralen  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
quinolines  (ISO)
resveratrol  (ISO)
rifaximin  (ISO)
ritonavir  (ISO)
rosuvastatin  (ISO)
rotenone  (ISO)
Salidroside  (EXP)
Selamectin  (ISO)
senecionine  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
stigmasterol  (EXP)
streptozocin  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
taurine  (EXP)
tauro-beta-muricholic acid  (EXP)
taurocholic acid  (EXP,ISO)
taurodeoxycholic acid  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trifloxystrobin  (ISO)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
uranium atom  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (ISO)
vincristine  (ISO)
vinorelbine  (ISO)
Yangonin  (EXP,ISO)
zinc acetate  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bile acid and bile salt transport  (ISO)
bile acid metabolic process  (IMP,ISO)
bile acid signaling pathway  (IBA,IMP,ISO)
cell differentiation  (IBA)
cell-cell junction assembly  (IMP)
cellular glucose homeostasis  (IDA)
cellular response to bile acid  (ISO)
cellular response to fatty acid  (ISO)
cellular response to lipopolysaccharide  (IMP)
cellular response to organonitrogen compound  (IMP)
cellular response to xenobiotic stimulus  (ISO)
cellular triglyceride homeostasis  (ISO)
cholesterol homeostasis  (IMP,ISO)
defense response to bacterium  (IDA)
digestive tract development  (ISO)
fatty acid homeostasis  (IMP)
glucose homeostasis  (IDA,ISO)
hepatocyte proliferation  (ISO)
histone H3-R17 methylation  (ISO)
immune system process  (IEA)
inflammatory response  (IEA)
innate immune response  (IEA)
intracellular bile acid receptor signaling pathway  (ISO)
intracellular receptor signaling pathway  (IMP)
leukocyte migration involved in inflammatory response  (ISO)
lipid localization  (ISO)
liver regeneration  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (IMP,ISO)
negative regulation of inflammatory response  (IBA,IMP)
negative regulation of interferon-gamma production  (IMP,ISO)
negative regulation of interleukin-1 production  (IMP)
negative regulation of interleukin-2 production  (IMP)
negative regulation of interleukin-6 production  (IDA)
negative regulation of monocyte chemotactic protein-1 production  (IMP)
negative regulation of NF-kappaB transcription factor activity  (IMP)
negative regulation of transcription by RNA polymerase II  (IBA,IMP,ISO)
negative regulation of triglyceride biosynthetic process  (ISO)
negative regulation of tumor necrosis factor production  (IMP,ISO)
negative regulation of tumor necrosis factor-mediated signaling pathway  (IMP)
negative regulation of very-low-density lipoprotein particle remodeling  (IDA,ISO)
nitrogen catabolite activation of transcription from RNA polymerase II promoter  (IC)
Notch signaling pathway  (IDA)
positive regulation of adipose tissue development  (IMP)
positive regulation of ammonia assimilation cycle  (IMP)
positive regulation of gene expression  (ISO)
positive regulation of glutamate metabolic process  (IMP)
positive regulation of insulin receptor signaling pathway  (IDA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IMP)
positive regulation of interleukin-17 production  (ISO)
positive regulation of phosphatidic acid biosynthetic process  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IMP,ISO)
positive regulation of transcription, DNA-templated  (IDA,ISO)
regulation of bile acid secretion  (ISO)
regulation of carbohydrate metabolic process  (ISO)
regulation of gene expression  (ISO)
regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
regulation of lipid storage  (ISO)
regulation of low-density lipoprotein particle clearance  (ISO)
regulation of transcription by RNA polymerase II  (IGI,ISO)
regulation of transcription, DNA-templated  (ISO)
regulation of urea metabolic process  (IMP)
response to 17alpha-ethynylestradiol  (ISO)
response to cholesterol  (ISO)
response to ethanol  (ISO)
response to fenofibrate  (ISO)
response to glucose  (ISO)
response to lipopolysaccharide  (ISO)
response to norepinephrine  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to xenobiotic stimulus  (ISO)
toll-like receptor 4 signaling pathway  (ISO)
toll-like receptor 9 signaling pathway  (IMP)
triglyceride homeostasis  (IDA,ISO)

Cellular Component
chromatin  (IC,ISO)
euchromatin  (ISO)
nucleus  (ISO)
receptor complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bile composition  (IAGP)
abnormal bile salt homeostasis  (IAGP)
abnormal bile salt level  (IAGP)
abnormal bile secretion  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver perisinusoidal space morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal liver sinusoid morphology  (IAGP)
cachexia  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased epididymal fat pad weight  (IAGP)
decreased interscapular fat pad weight  (IAGP)
decreased retroperitoneal fat pad weight  (IAGP)
decreased susceptibility to weight gain  (IAGP)
decreased total body fat amount  (IAGP)
decreased white fat cell size  (IAGP)
enlarged gallbladder  (IAGP)
enlarged liver  (IAGP)
focal hepatic necrosis  (IAGP)
hepatic steatosis  (IAGP)
impaired glucose tolerance  (IAGP)
increased bile salt level  (IAGP)
increased cecum weight  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating aspartate transaminase level  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating phospholipid level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased energy expenditure  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased hepatocyte proliferation  (IAGP)
increased liver adenoma incidence  (IAGP)
increased liver cholesterol level  (IAGP)
increased liver triglyceride level  (IAGP)
increased liver tumor incidence  (IAGP)
increased liver weight  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased spleen weight  (IAGP)
jaundice  (IAGP)
liver degeneration  (IAGP)
liver inflammation  (IAGP)
References

References - curated
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Additional References at PubMed
PMID:7760852   PMID:8835541   PMID:10349636   PMID:11030617   PMID:11042159   PMID:11076861   PMID:11208732   PMID:11279518   PMID:12004058   PMID:12062799   PMID:12393883   PMID:12421815  
PMID:12456679   PMID:12477932   PMID:12519762   PMID:12529392   PMID:12718892   PMID:12891557   PMID:12917447   PMID:12923173   PMID:12949731   PMID:14592843   PMID:14681479   PMID:14729567  
PMID:15371561   PMID:15466244   PMID:15489334   PMID:15558057   PMID:15564327   PMID:15590640   PMID:15611112   PMID:15721319   PMID:15817812   PMID:15899888   PMID:15981587   PMID:16002565  
PMID:16023103   PMID:16141072   PMID:16141073   PMID:16186601   PMID:16224116   PMID:16251721   PMID:16269825   PMID:16284190   PMID:16327028   PMID:16357057   PMID:16410358   PMID:16423920  
PMID:16446356   PMID:16473946   PMID:16606610   PMID:16609145   PMID:16614213   PMID:16682417   PMID:16778009   PMID:16825595   PMID:16844773   PMID:16912278   PMID:16971476   PMID:16973757  
PMID:17110163   PMID:17205580   PMID:17289919   PMID:17426284   PMID:17440045   PMID:17521389   PMID:17545158   PMID:17622954   PMID:17624466   PMID:17660268   PMID:17720959   PMID:17931734  
PMID:17950284   PMID:17963822   PMID:18287559   PMID:18436567   PMID:18448072   PMID:18495661   PMID:18562803   PMID:18648086   PMID:18703564   PMID:18820241   PMID:18842595   PMID:18948497  
PMID:18972444   PMID:18988759   PMID:19028791   PMID:19030180   PMID:19047134   PMID:19056864   PMID:19072826   PMID:19118524   PMID:19182371   PMID:19204003   PMID:19386638   PMID:19407337  
PMID:19556342   PMID:19605523   PMID:19608735   PMID:19718444   PMID:19776172   PMID:19805516   PMID:19815629   PMID:19864602   PMID:19880446   PMID:19883617   PMID:19910507   PMID:19965601  
PMID:19965603   PMID:19996107   PMID:20026603   PMID:20059953   PMID:20060466   PMID:20091679   PMID:20185821   PMID:20211986   PMID:20233723   PMID:20373033   PMID:20375256   PMID:20444884  
PMID:20447400   PMID:20483916   PMID:20531290   PMID:20699418   PMID:20842631   PMID:20850540   PMID:20851881   PMID:20868235   PMID:20957146   PMID:21081494   PMID:21123943   PMID:21195347  
PMID:21224055   PMID:21242261   PMID:21267068   PMID:21296199   PMID:21386911   PMID:21430080   PMID:21431940   PMID:21504366   PMID:21593203   PMID:21619550   PMID:21642744   PMID:21690373  
PMID:21757002   PMID:21804189   PMID:21862726   PMID:21873635   PMID:22135065   PMID:22144677   PMID:22178739   PMID:22261820   PMID:22268101   PMID:22278336   PMID:22285937   PMID:22290433  
PMID:22296850   PMID:22447981   PMID:22467244   PMID:22474109   PMID:22492528   PMID:22540009   PMID:22565294   PMID:22643070   PMID:22661717   PMID:22730081   PMID:22952826   PMID:23051670  
PMID:23056173   PMID:23172628   PMID:23178280   PMID:23205607   PMID:23348961   PMID:23372731   PMID:23395169   PMID:23460643   PMID:23462932   PMID:23507574   PMID:23519696   PMID:23530060  
PMID:23541942   PMID:23549084   PMID:23609136   PMID:23747249   PMID:23861371   PMID:23916961   PMID:24004655   PMID:24007921   PMID:24037988   PMID:24038130   PMID:24043304   PMID:24064762  
PMID:24091600   PMID:24146773   PMID:24211198   PMID:24268772   PMID:24269813   PMID:24291500   PMID:24333182   PMID:24338587   PMID:24389307   PMID:24464484   PMID:24531544   PMID:24656817  
PMID:24670636   PMID:24721598   PMID:24875360   PMID:24952961   PMID:25138215   PMID:25156247   PMID:25183423   PMID:25184625   PMID:25278094   PMID:25339829   PMID:25363753   PMID:25383523  
PMID:25400456   PMID:25425577   PMID:25446530   PMID:25460735   PMID:25470824   PMID:25496033   PMID:25500885   PMID:25506828   PMID:25545350   PMID:25559344   PMID:25593129   PMID:25599407  
PMID:25651182   PMID:25655198   PMID:25719402   PMID:25870546   PMID:26134028   PMID:26238153   PMID:26241054   PMID:26332085   PMID:26474702   PMID:26482353   PMID:26505219   PMID:26554605  
PMID:26620317   PMID:26655953   PMID:26670557   PMID:26728993   PMID:26740296   PMID:26811456   PMID:26812075   PMID:26848619   PMID:26899873   PMID:27146480   PMID:27170759   PMID:27358174  
PMID:27376807   PMID:27383204   PMID:27471003   PMID:27531557   PMID:27624003   PMID:27639801   PMID:27758768   PMID:27820600   PMID:27821667   PMID:27889186   PMID:27896916   PMID:27956139  
PMID:28065787   PMID:28125709   PMID:28130067   PMID:28181583   PMID:28223344   PMID:28380377   PMID:28400119   PMID:28446510   PMID:28449117   PMID:28478385   PMID:28496104   PMID:28505368  
PMID:28586124   PMID:28596381   PMID:28647362   PMID:28669602   PMID:28711154   PMID:28714273   PMID:28787755   PMID:28852062   PMID:28891815   PMID:28894223   PMID:28895119   PMID:28951211  
PMID:28956216   PMID:29028769   PMID:29089371   PMID:29107284   PMID:29142166   PMID:29377207   PMID:29718219   PMID:29730159   PMID:29739889   PMID:29771182   PMID:29925501   PMID:29929982  
PMID:29940597   PMID:29976576   PMID:29981427   PMID:30098335   PMID:30122655   PMID:30208322   PMID:30260705   PMID:30337250   PMID:30354208   PMID:30464200   PMID:30520052   PMID:30536462  
PMID:30580099   PMID:30653340   PMID:30794774   PMID:30803859   PMID:30862680   PMID:30967475   PMID:30996006   PMID:31298930   PMID:31387746   PMID:31470114   PMID:31485455   PMID:31506275  
PMID:31673703   PMID:31776512   PMID:31862954   PMID:31875848   PMID:31911428   PMID:31932588   PMID:32006644   PMID:32034442   PMID:32145254   PMID:32170842   PMID:32305491   PMID:32325033  
PMID:32446390   PMID:32450881   PMID:32461639   PMID:32661285   PMID:32712104   PMID:33029504   PMID:33029898   PMID:33068587   PMID:33318189   PMID:33368684   PMID:33462514   PMID:33482151  
PMID:33526687   PMID:33568795   PMID:33594777   PMID:33980856  


Genomics

Comparative Map Data
Nr1h4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,290,096 - 89,369,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1089,290,096 - 89,369,447 (-)Ensembl
GRCm381089,454,234 - 89,533,645 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,454,234 - 89,533,585 (-)EnsemblGRCm38mm10GRCm38
MGSCv371088,916,979 - 88,996,367 (-)NCBIGRCm37mm9NCBIm37
MGSCv361088,884,177 - 88,936,426 (-)NCBImm8
Celera1091,441,224 - 91,574,747 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1044.98NCBI
NR1H4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12100,473,708 - 100,564,414 (+)EnsemblGRCh38hg38GRCh38
GRCh3812100,473,866 - 100,564,414 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712100,867,644 - 100,958,192 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,391,810 - 99,481,774 (+)NCBINCBI36hg18NCBI36
Build 341299,370,146 - 99,460,111NCBI
Celera12100,532,992 - 100,622,995 (+)NCBI
Cytogenetic Map12q23.1NCBI
HuRef1297,928,334 - 98,018,410 (+)NCBIHuRef
CHM1_112100,833,597 - 100,923,679 (+)NCBICHM1_1
Nr1h4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2723,846,122 - 23,942,085 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl723,846,122 - 23,942,047 (-)Ensembl
Rnor_6.0730,003,429 - 30,162,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,003,429 - 30,162,056 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,170,397 - 30,214,796 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0730,104,960 - 30,107,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,189,759 - 26,307,061 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1726,210,029 - 26,327,332 (-)NCBI
Celera720,992,814 - 21,085,820 (-)NCBICelera
Cytogenetic Map7q13NCBI
Nr1h4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540536,160,049 - 36,237,751 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540536,160,360 - 36,236,258 (+)NCBIChiLan1.0ChiLan1.0
NR1H4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112101,457,885 - 101,548,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,457,885 - 101,548,058 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01298,052,778 - 98,144,085 (+)NCBIMhudiblu_PPA_v0panPan3
NR1H4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,497,313 - 39,608,120 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,536,290 - 39,608,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1539,876,387 - 39,987,365 (+)NCBI
ROS_Cfam_1.01540,161,103 - 40,272,109 (+)NCBI
UMICH_Zoey_3.11539,418,531 - 39,529,420 (+)NCBI
UNSW_CanFamBas_1.01539,525,061 - 39,636,033 (+)NCBI
UU_Cfam_GSD_1.01539,799,183 - 39,910,169 (+)NCBI
Nr1h4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,304,852 - 20,379,409 (-)NCBI
SpeTri2.0NW_00493649213,315,265 - 13,365,186 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1H4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,604,288 - 83,684,604 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1583,607,222 - 83,732,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2587,754,914 - 87,828,507 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR1H4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11195,792,428 - 95,877,989 (+)NCBI
ChlSab1.1 Ensembl1195,792,996 - 95,878,293 (+)Ensembl
Vero_WHO_p1.0NW_023666037149,156,310 - 149,247,016 (-)NCBI
Nr1h4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247507,222,306 - 7,303,809 (-)NCBI

Position Markers
AI646847  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38444,991,325 - 44,991,430UniSTSGRCm38
MGSCv37445,004,197 - 45,004,302UniSTSGRCm37
Celera1091,541,750 - 91,541,855UniSTS
Celera445,011,385 - 45,011,490UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS
Whitehead/MRC_RH4753.23UniSTS
AI957360  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381089,454,585 - 89,454,729UniSTSGRCm38
MGSCv371088,917,330 - 88,917,474UniSTSGRCm37
Celera1091,441,575 - 91,441,719UniSTS
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS
Whitehead/MRC_RH101026.69UniSTS
U09416  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381089,454,585 - 89,454,679UniSTSGRCm38
MGSCv371088,917,330 - 88,917,424UniSTSGRCm37
Celera1091,441,575 - 91,441,669UniSTS
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS
Whitehead/MRC_RH101028.22UniSTS
UniSTS:234914  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38444,991,700 - 44,991,944UniSTSGRCm38
MGSCv37445,004,572 - 45,004,816UniSTSGRCm37
Celera1091,542,124 - 91,542,379UniSTS
Celera445,011,760 - 45,012,004UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS
UniSTS:236437  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38444,993,195 - 44,993,332UniSTSGRCm38
GRCm381089,554,905 - 89,555,042UniSTSGRCm38
MGSCv371089,017,650 - 89,017,787UniSTSGRCm37
MGSCv37445,006,067 - 45,006,204UniSTSGRCm37
Celera445,013,255 - 45,013,392UniSTS
Celera1091,543,648 - 91,543,785UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS
Nr1h4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C2UniSTS
cM Map1050.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082242550116242550Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082473556116473795Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082473556116473795Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082473556116473795Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082473556116473795Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082473556116473795Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082473556116473795Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082556941116557090Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8265510491020240Mouse
12910789Pwgrq19_mpost-weaning growth rate QTL 19 (mouse)108299286692333194Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83181141117181274Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084243786122205623Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84243786122205623Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84243786122205623Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084243786122205623Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084243786122205623Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085619118118661448Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086877747120877895Mouse
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1087073224121073368Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1087073224121073368Mouse
1357831Igf1sl2_mIGF-1 serum levels 2 (mouse)Not determined1087858265100100416Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088252393122252530Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined89000595123000595Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir421mmu-miR-421-3pOncomiRDBexternal_infoNANA22446874
Mir421mmu-miR-421-3pOncomiRDBexternal_infoNANA22146319

Predicted Target Of
Summary Value
Count of predictions:383
Count of miRNA genes:138
Interacting mature miRNAs:157
Transcripts:ENSMUST00000058126, ENSMUST00000105296, ENSMUST00000105297
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001163700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030244963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001779493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC152417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF293370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY366407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY366408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000058126   ⟹   ENSMUSP00000053092
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1089,290,096 - 89,342,511 (-)Ensembl
GRCm38.p6 Ensembl1089,454,234 - 89,506,649 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105296   ⟹   ENSMUSP00000100933
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1089,290,096 - 89,342,520 (-)Ensembl
GRCm38.p6 Ensembl1089,454,234 - 89,506,658 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105297   ⟹   ENSMUSP00000100934
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1089,290,235 - 89,369,447 (-)Ensembl
GRCm38.p6 Ensembl1089,454,373 - 89,533,585 (-)Ensembl
RefSeq Acc Id: NM_001163504   ⟹   NP_001156976
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,096 - 89,369,484 (-)NCBI
GRCm381089,454,234 - 89,533,622 (-)NCBI
MGSCv371088,916,979 - 88,996,367 (-)RGD
Celera1091,441,224 - 91,574,747 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001163700   ⟹   NP_001157172
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,096 - 89,342,520 (-)NCBI
GRCm381089,454,234 - 89,506,658 (-)NCBI
MGSCv371088,916,979 - 88,996,367 (-)RGD
Celera1091,441,224 - 91,574,747 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001385711   ⟹   NP_001372640
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,235 - 89,369,465 (-)NCBI
RefSeq Acc Id: NM_009108   ⟹   NP_033134
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,096 - 89,342,520 (-)NCBI
GRCm381089,454,234 - 89,506,658 (-)NCBI
MGSCv371088,916,979 - 88,996,367 (-)RGD
Celera1091,441,224 - 91,574,747 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513391   ⟹   XP_006513454
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,235 - 89,353,334 (-)NCBI
GRCm381089,454,373 - 89,517,472 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030244963   ⟹   XP_030100823
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,235 - 89,352,646 (-)NCBI
GRCm381089,454,373 - 89,516,785 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001779493
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391089,290,338 - 89,342,542 (-)NCBI
GRCm381089,454,476 - 89,506,680 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033134   ⟸   NM_009108
- Peptide Label: isoform 3
- UniProtKB: Q3V1T8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156976   ⟸   NM_001163504
- Peptide Label: isoform 2
- UniProtKB: Q60641 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157172   ⟸   NM_001163700
- Peptide Label: isoform 1
- UniProtKB: Q60641 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006513454   ⟸   XM_006513391
- Peptide Label: isoform X1
- UniProtKB: Q60641 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030100823   ⟸   XM_030244963
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000100933   ⟸   ENSMUST00000105296
RefSeq Acc Id: ENSMUSP00000100934   ⟸   ENSMUST00000105297
RefSeq Acc Id: ENSMUSP00000053092   ⟸   ENSMUST00000058126
RefSeq Acc Id: NP_001372640   ⟸   NM_001385711
- Peptide Label: isoform 4
Protein Domains
NR LBD   Nuclear receptor

Promoters
RGD ID:6819674
Promoter ID:MM_KWN:5305
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:NM_001163700,   OTTMUST00000054480,   UC007GSI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361088,969,124 - 88,969,624 (-)MPROMDB
RGD ID:8673010
Promoter ID:EPDNEW_M14535
Type:multiple initiation site
Name:Nr1h4_1
Description:Mus musculus nuclear receptor subfamily 1, group H, member 4, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14536  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381089,506,638 - 89,506,698EPDNEW
RGD ID:8673012
Promoter ID:EPDNEW_M14536
Type:initiation region
Name:Nr1h4_2
Description:Mus musculus nuclear receptor subfamily 1, group H, member 4, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14535  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381089,533,563 - 89,533,623EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1352464 AgrOrtholog
Ensembl Genes ENSMUSG00000047638 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000053092 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000100933 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000100934 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000058126 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000105296 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000105297 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NR_LBD_NR1H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThyrH_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20186 UniProtKB/Swiss-Prot
MGD MGI:1352464 ENTREZGENE
NCBI Gene 20186 ENTREZGENE
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nr1h4 PhenoGen
PRINTS STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROIDHORMR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NR1H4_MOUSE UniProtKB/Swiss-Prot
  Q3V1T8 ENTREZGENE, UniProtKB/TrEMBL
  Q60641 ENTREZGENE
  Q99MT9_MOUSE UniProtKB/TrEMBL
UniProt Secondary D3YTT2 UniProtKB/Swiss-Prot
  E9QJW2 UniProtKB/Swiss-Prot
  Q60642 UniProtKB/Swiss-Prot
  Q60643 UniProtKB/Swiss-Prot