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Gene: Dock7 (dedicator of cytokinesis 7) Mus musculus
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Symbol: Dock7
Name: dedicator of cytokinesis 7
Description: Exhibits Rac GTPase binding activity. Involved in several processes, including hematopoietic progenitor cell differentiation; negative regulation of cold-induced thermogenesis; and nervous system development. Predicted to colocalize with the COP9 signalosome. Used to study platelet storage pool deficiency. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 23. Is expressed in several structures, including alimentary system; central nervous system; lung; placenta; and sensory organ. Orthologous to human DOCK7 (dedicator of cytokinesis 7); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110056M06Rik; dedicator of cytokinesis protein 7; Gm430; m; mKIAA1771
Orthologs:
Homo sapiens (human) : DOCK7 (dedicator of cytokinesis 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dock7 (dedicator of cytokinesis 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dock7 (dedicator of cytokinesis 7)
Pan paniscus (bonobo/pygmy chimpanzee) : DOCK7 (dedicator of cytokinesis 7)
Canis lupus familiaris (dog) : DOCK7 (dedicator of cytokinesis 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dock7 (dedicator of cytokinesis 7)
Sus scrofa (pig) : DOCK7 (dedicator of cytokinesis 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38498,936,659 - 99,130,953 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37498,603,356 - 98,787,606 (-)NCBIGRCm37mm9NCBIm37
MGSCv36498,428,693 - 98,612,878 (-)NCBImm8
Celera497,303,722 - 97,492,465 (-)NCBICelera
Cytogenetic Map4 C6NCBI
cM Map445.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dock7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320319
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.