DOCK8 (dedicator of cytokinesis 8) - Rat Genome Database

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Gene: DOCK8 (dedicator of cytokinesis 8) Homo sapiens
Analyze
Symbol: DOCK8
Name: dedicator of cytokinesis 8
RGD ID: 1603953
HGNC Page HGNC
Description: Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including positive regulation of GTPase activity; positive regulation of T cell migration; and positive regulation of establishment of T cell polarity. Acts upstream of or within memory T cell proliferation. Located in cytoplasm and leading edge membrane. Implicated in several diseases, including atopic dermatitis; autosomal dominant non-syndromic intellectual disability 2; hyper IgE recurrent infection syndrome 2; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; and viral infectious disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1200017A24Rik; dedicator of cytokinesis protein 8; epididymis luminal protein 205; FLJ00026; FLJ00152; FLJ00346; HEL-205; MRD2; ZIR8
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9214,854 - 465,259 (+)EnsemblGRCh38hg38GRCh38
GRCh389211,296 - 465,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379214,865 - 465,255 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369263,048 - 455,255 (+)NCBINCBI36hg18NCBI36
Celera9129,697 - 382,253 (+)NCBI
Cytogenetic Map9p24.3NCBI
HuRef9168,609 - 417,080 (+)NCBIHuRef
CHM1_19215,319 - 464,907 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal facial shape  (IAGP)
Abnormal hippocampus morphology  (IAGP)
Anal canal squamous carcinoma  (IAGP)
Asthma  (IAGP)
Atonic seizure  (IAGP)
Atopic dermatitis  (IAGP)
Autistic behavior  (IAGP)
Autoimmune antibody positivity  (IAGP)
Autosomal recessive inheritance  (IAGP)
B lymphocytopenia  (IAGP)
Bilateral generalized polymicrogyria  (IAGP)
Bilateral tonic-clonic seizure  (IAGP)
Cerebral atrophy  (IAGP)
Cerebral vasculitis  (IAGP)
Cerebral visual impairment  (IAGP)
Chorea  (IAGP)
Chronic otitis media  (IAGP)
Decreased circulating total IgM  (IAGP)
Decreased proportion of CD4+CD25+ regulatory T cells  (IAGP)
Decreased proportion of CD4-positive T cells  (IAGP)
Decreased proportion of memory T cells  (IAGP)
Decreased proportion of naive CD8 T cells  (IAGP)
Dilation of lateral ventricles  (IAGP)
Dyskinesia  (IAGP)
Eczema  (IAGP)
Eosinophilia  (IAGP)
Epileptic spasm  (IAGP)
Eyelid myoclonus  (IAGP)
Focal emotional seizure with laughing  (IAGP)
Focal impaired awareness seizure  (IAGP)
Focal motor seizure  (IAGP)
Gastroesophageal reflux  (IAGP)
Gastrostomy tube feeding in infancy  (IAGP)
Generalized myoclonic seizure  (IAGP)
Generalized tonic seizure  (IAGP)
Hemiplegia  (IAGP)
Hypereosinophilia  (IAGP)
Hypoplasia of the corpus callosum  (IAGP)
Increased circulating IgE level  (IAGP)
Increased proportion of exhausted T cells  (IAGP)
Infantile onset  (IAGP)
Intellectual disability  (IAGP)
Intellectual disability, mild  (IAGP)
Intellectual disability, moderate  (IAGP)
Intellectual disability, profound  (IAGP)
Intellectual disability, severe  (IAGP)
Leukoencephalopathy  (IAGP)
Microcephaly  (IAGP)
Neoplasm  (IAGP)
Oculogyric crisis  (IAGP)
Onychomycosis  (IAGP)
Oral-pharyngeal dysphagia  (IAGP)
Pneumonia  (IAGP)
Poor speech  (IAGP)
Recurrent bacterial infections  (IAGP)
Recurrent bacterial skin infections  (IAGP)
Recurrent candida infections  (IAGP)
Recurrent cutaneous abscess formation  (IAGP)
Recurrent fungal infections  (IAGP)
Recurrent respiratory infections  (IAGP)
Recurrent sinopulmonary infections  (IAGP)
Recurrent sinusitis  (IAGP)
Recurrent viral infections  (IAGP)
Schizophrenia  (IAGP)
Scoliosis  (IAGP)
Self-injurious behavior  (IAGP)
Severe muscular hypotonia  (IAGP)
Short stature  (IAGP)
Skin ulcer  (IAGP)
Sleep disturbance  (IAGP)
Spasticity  (IAGP)
Squamous cell carcinoma  (IAGP)
Squamous cell carcinoma of the vulva  (IAGP)
Status epilepticus  (IAGP)
Stereotypy  (IAGP)
Subarachnoid hemorrhage  (IAGP)
T lymphocytopenia  (IAGP)
Typical absence seizure  (IAGP)
Verrucae  (IAGP)
Widened subarachnoid space  (IAGP)
References

References - curated
1. Al-Herz W, etal., Clin Immunol. 2012 Jun;143(3):266-72. doi: 10.1016/j.clim.2012.03.002. Epub 2012 Mar 30.
2. Alroqi FJ, etal., J Clin Immunol. 2017 Nov;37(8):811-819. doi: 10.1007/s10875-017-0451-1. Epub 2017 Oct 23.
3. Arndt T, etal., Diabetologia. 2015 Dec;58(12):2800-9. doi: 10.1007/s00125-015-3757-7. Epub 2015 Sep 12.
4. Dasouki M, etal., Clin Immunol. 2011 Nov;141(2):128-32. doi: 10.1016/j.clim.2011.06.003. Epub 2011 Jun 21.
5. Engelhardt KR, etal., J Allergy Clin Immunol. 2015 Aug;136(2):402-12. doi: 10.1016/j.jaci.2014.12.1945. Epub 2015 Feb 25.
6. Fan M, etal., Virol Sin. 2020 Aug;35(4):378-387. doi: 10.1007/s12250-020-00200-x. Epub 2020 Apr 15.
7. Flesch IE, etal., Immunol Cell Biol. 2015 Jul;93(6):517-21. doi: 10.1038/icb.2015.32. Epub 2015 Mar 17.
8. Janssen E, etal., J Allergy Clin Immunol. 2014 Dec;134(6):1365-1374. doi: 10.1016/j.jaci.2014.07.042. Epub 2014 Sep 11.
9. Jouhadi Z, etal., Pediatrics. 2014 Nov;134(5):e1458-63. doi: 10.1542/peds.2013-1383.
10. Kasap N, etal., Clin Immunol. 2020 Dec 7;223:108645. doi: 10.1016/j.clim.2020.108645.
11. OMIM Disease Annotation Pipeline
12. Randall KL, etal., J Exp Med. 2011 Oct 24;208(11):2305-20. doi: 10.1084/jem.20110345. Epub 2011 Oct 17.
13. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. RGD automated import pipeline for gene-chemical interactions
15. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
16. Sanal O, etal., J Clin Immunol. 2012 Aug;32(4):698-708. doi: 10.1007/s10875-012-9664-5. Epub 2012 Apr 4.
Additional References at PubMed
PMID:8889548   PMID:10729223   PMID:11214971   PMID:12432077   PMID:12477932   PMID:14702039   PMID:15164053   PMID:15231748   PMID:15304341   PMID:15489334   PMID:16344560   PMID:16391785  
PMID:18029348   PMID:18060736   PMID:19640199   PMID:19776401   PMID:19946888   PMID:20004785   PMID:20379614   PMID:20467437   PMID:20596660   PMID:21058221   PMID:21178271   PMID:21178272  
PMID:21931011   PMID:21969276   PMID:22139419   PMID:22581261   PMID:22876580   PMID:22942019   PMID:22968740   PMID:23251661   PMID:23374272   PMID:23380217   PMID:23455509   PMID:23859592  
PMID:23891736   PMID:23911989   PMID:23929855   PMID:24255178   PMID:24698323   PMID:24722188   PMID:24898675   PMID:25220305   PMID:25416956   PMID:25422492   PMID:25428919   PMID:26186194  
PMID:26235511   PMID:26496610   PMID:26592211   PMID:26659092   PMID:26799599   PMID:26871637   PMID:26883462   PMID:27107014   PMID:27350570   PMID:27554822   PMID:27890707   PMID:28028151  
PMID:28065530   PMID:28067314   PMID:28225217   PMID:28366940   PMID:28514442   PMID:29419892   PMID:29467281   PMID:29472447   PMID:29892012   PMID:29930340   PMID:30021884   PMID:30120291  
PMID:30252138   PMID:30397357   PMID:30442766   PMID:30689480   PMID:31242861   PMID:31515488   PMID:31596517   PMID:31630188   PMID:31723608   PMID:32203420   PMID:32296183   PMID:32372632  
PMID:33545980  


Genomics

Comparative Map Data
DOCK8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9214,854 - 465,259 (+)EnsemblGRCh38hg38GRCh38
GRCh389211,296 - 465,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379214,865 - 465,255 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369263,048 - 455,255 (+)NCBINCBI36hg18NCBI36
Celera9129,697 - 382,253 (+)NCBI
Cytogenetic Map9p24.3NCBI
HuRef9168,609 - 417,080 (+)NCBIHuRef
CHM1_19215,319 - 464,907 (+)NCBICHM1_1
Dock8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391924,976,753 - 25,179,796 (+)NCBIGRCm39mm39
GRCm39 Ensembl1924,976,898 - 25,179,796 (+)Ensembl
GRCm381924,999,321 - 25,202,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1924,999,534 - 25,202,432 (+)EnsemblGRCm38mm10GRCm38
MGSCv371925,074,019 - 25,276,922 (+)NCBIGRCm37mm9NCBIm37
MGSCv361925,066,626 - 25,269,529 (+)NCBImm8
Celera1925,771,990 - 25,988,915 (+)NCBICelera
Cytogenetic Map19BNCBI
Dock8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21222,649,309 - 222,842,474 (+)NCBI
Rnor_6.0 Ensembl1242,959,488 - 243,153,465 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01242,934,685 - 243,153,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01250,200,507 - 250,417,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,441,384 - 228,634,717 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1219,852,410 - 220,042,463 (+)NCBICelera
Cytogenetic Map1q51NCBI
Dock8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554344,867,016 - 5,049,118 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554344,849,147 - 5,050,545 (+)NCBIChiLan1.0ChiLan1.0
DOCK8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19201,156 - 446,910 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9201,156 - 446,910 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v096,791 - 256,837 (+)NCBIMhudiblu_PPA_v0panPan3
DOCK8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1189,152,456 - 89,379,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl189,150,856 - 89,378,013 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha189,621,978 - 89,850,471 (+)NCBI
ROS_Cfam_1.0189,701,521 - 89,930,127 (+)NCBI
UMICH_Zoey_3.1189,347,665 - 89,576,215 (+)NCBI
UNSW_CanFamBas_1.0189,059,801 - 89,288,656 (+)NCBI
UU_Cfam_GSD_1.0189,820,804 - 90,055,669 (+)NCBI
Dock8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947136,597,710 - 136,810,653 (+)NCBI
SpeTri2.0NW_0049365034,362,573 - 4,575,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,256,009 - 221,491,953 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,257,771 - 221,491,889 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,516,602 - 247,752,057 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11279,060,579 - 79,298,145 (-)NCBI
ChlSab1.1 Ensembl1279,060,425 - 79,298,164 (-)Ensembl
Vero_WHO_p1.0NW_02366603867,459,893 - 67,698,795 (-)NCBI
Dock8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247364,959,482 - 5,195,182 (+)NCBI

Position Markers
D9S917  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379444,262 - 444,392UniSTSGRCh37
Build 369434,262 - 434,392RGDNCBI36
Celera9361,246 - 361,388RGD
Cytogenetic Map9p24.3UniSTS
HuRef9396,079 - 396,209UniSTS
Marshfield Genetic Map90.0UniSTS
Marshfield Genetic Map9 RGD
deCODE Assembly Map90.0UniSTS
RH65569  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379251,050 - 251,173UniSTSGRCh37
Build 369241,050 - 241,173RGDNCBI36
Celera9165,881 - 166,004RGD
Cytogenetic Map9p24.3UniSTS
HuRef9204,709 - 204,832UniSTS
GeneMap99-GB4 RH Map90.0UniSTS
SHGC-18075  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379389,565 - 389,729UniSTSGRCh37
Build 369379,565 - 379,729RGDNCBI36
Celera9306,541 - 306,705RGD
Cytogenetic Map9p24.3UniSTS
HuRef9342,134 - 342,298UniSTS
Whitehead-RH Map913.7UniSTS
Whitehead-YAC Contig Map9 UniSTS
A008P36  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379359,583 - 359,684UniSTSGRCh37
Build 369349,583 - 349,684RGDNCBI36
Celera9276,501 - 276,602RGD
Cytogenetic Map9p24.3UniSTS
HuRef9312,165 - 312,266UniSTS
GeneMap99-GB4 RH Map91.7UniSTS
RH46516  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379219,801 - 219,947UniSTSGRCh37
Build 369209,801 - 209,947RGDNCBI36
Celera9134,633 - 134,779RGD
Cytogenetic Map9p24.3UniSTS
HuRef9173,544 - 173,690UniSTS
RH80320  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379401,643 - 401,724UniSTSGRCh37
Build 369391,643 - 391,724RGDNCBI36
Celera9318,627 - 318,708RGD
Cytogenetic Map9p24.3UniSTS
HuRef9353,479 - 353,560UniSTS
GeneMap99-GB4 RH Map92.81UniSTS
RH118948  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379437,853 - 438,141UniSTSGRCh37
Build 369427,853 - 428,141RGDNCBI36
Celera9354,837 - 355,125RGD
Cytogenetic Map9p24.3UniSTS
HuRef9389,670 - 389,958UniSTS
TNG Radiation Hybrid Map90.0UniSTS
STS-T92908  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379359,594 - 359,723UniSTSGRCh37
Build 369349,594 - 349,723RGDNCBI36
Celera9276,512 - 276,641RGD
Cytogenetic Map9p24.3UniSTS
HuRef9312,176 - 312,305UniSTS
GeneMap99-GB4 RH Map99.78UniSTS
D9S913  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379444,173 - 444,558UniSTSGRCh37
Build 369434,173 - 434,558RGDNCBI36
Celera9361,157 - 361,554RGD
Cytogenetic Map9p24.3UniSTS
HuRef9395,990 - 396,375UniSTS
WI-17492  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379465,077 - 465,223UniSTSGRCh37
Build 369455,077 - 455,223RGDNCBI36
Celera9382,071 - 382,217RGD
Cytogenetic Map9p24.3UniSTS
HuRef9416,898 - 417,044UniSTS
GeneMap99-GB4 RH Map911.42UniSTS
Whitehead-RH Map90.0UniSTS
A008I30  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379465,081 - 465,182UniSTSGRCh37
Build 369455,081 - 455,182RGDNCBI36
Celera9382,075 - 382,176RGD
Cytogenetic Map9p24.3UniSTS
HuRef9416,902 - 417,003UniSTS
GeneMap99-GB4 RH Map916.71UniSTS
G29245  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379401,554 - 401,688UniSTSGRCh37
Build 369391,554 - 391,688RGDNCBI36
Celera9318,538 - 318,672RGD
Cytogenetic Map9p24.3UniSTS
HuRef9353,390 - 353,524UniSTS
RH36905  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map10p12.33UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map18p11.3-p11.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map3q27-q28UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map3q26.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.32UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map3q12.2-q12.3UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map11q12-q13.1UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map9q31.1UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map7q31.1-q31.2UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map10q21UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map4q25-q27UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map10q24.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map1p21.3UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map10q25-q26UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map7p14UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map16q22.1UniSTS
MFD455-AAT  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379444,223 - 444,510UniSTSGRCh37
Celera9361,207 - 361,506UniSTS
HuRef9396,040 - 396,327UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4715
Count of miRNA genes:1299
Interacting mature miRNAs:1689
Transcripts:ENST00000382329, ENST00000382331, ENST00000382341, ENST00000432829, ENST00000453981, ENST00000454469, ENST00000462618, ENST00000469197, ENST00000469391, ENST00000474772, ENST00000478380, ENST00000479404, ENST00000483757, ENST00000487230, ENST00000493666, ENST00000495184, ENST00000524396
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 691 719 219 6 1713 8 163 575 46 123 263 568 237 22 2
Low 1687 2074 1466 587 224 425 3712 1053 2650 267 1135 905 169 1 967 2360 3 2
Below cutoff 52 197 35 29 6 30 462 556 1016 21 53 113 5 406

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_017007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001190458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001193536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_203447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011518045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011518046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011518047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011518048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011518049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017015173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017015174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB191037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF194407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK024436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK093572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL158832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL583913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY117695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC045629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG388288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM680510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU532484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA503173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB147029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR004867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU668358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM991479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM991480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC736820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LS482371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000382329   ⟹   ENSP00000371766
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9366,251 - 465,255 (+)Ensembl
RefSeq Acc Id: ENST00000382331   ⟹   ENSP00000371768
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9366,229 - 405,099 (+)Ensembl
RefSeq Acc Id: ENST00000382341
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,050 - 340,620 (+)Ensembl
RefSeq Acc Id: ENST00000432829   ⟹   ENSP00000394888
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,865 - 465,259 (+)Ensembl
RefSeq Acc Id: ENST00000453981   ⟹   ENSP00000408464
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,048 - 465,259 (+)Ensembl
RefSeq Acc Id: ENST00000454469
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,868 - 340,620 (+)Ensembl
RefSeq Acc Id: ENST00000462618
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9463,555 - 465,247 (+)Ensembl
RefSeq Acc Id: ENST00000469197   ⟹   ENSP00000418587
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,854 - 286,636 (+)Ensembl
RefSeq Acc Id: ENST00000469391   ⟹   ENSP00000419438
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,070 - 464,526 (+)Ensembl
RefSeq Acc Id: ENST00000474772
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9311,958 - 314,466 (+)Ensembl
RefSeq Acc Id: ENST00000478380
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,066 - 312,941 (+)Ensembl
RefSeq Acc Id: ENST00000479404   ⟹   ENSP00000417082
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9215,171 - 289,579 (+)Ensembl
RefSeq Acc Id: ENST00000483757   ⟹   ENSP00000417691
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,059 - 381,387 (+)Ensembl
RefSeq Acc Id: ENST00000487230   ⟹   ENSP00000418318
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,050 - 304,703 (+)Ensembl
RefSeq Acc Id: ENST00000493666
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9420,116 - 426,953 (+)Ensembl
RefSeq Acc Id: ENST00000495184
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,084 - 465,241 (+)Ensembl
RefSeq Acc Id: ENST00000524396   ⟹   ENSP00000436628
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,865 - 340,620 (+)Ensembl
RefSeq Acc Id: ENST00000682121
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,865 - 291,983 (+)Ensembl
RefSeq Acc Id: ENST00000682249   ⟹   ENSP00000507731
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9273,046 - 314,466 (+)Ensembl
RefSeq Acc Id: ENST00000682260
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9369,664 - 399,770 (+)Ensembl
RefSeq Acc Id: ENST00000683406
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9407,019 - 465,255 (+)Ensembl
RefSeq Acc Id: ENST00000684166
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,868 - 291,494 (+)Ensembl
RefSeq Acc Id: ENST00000684384
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9214,868 - 313,960 (+)Ensembl
RefSeq Acc Id: ENST00000684637
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9440,382 - 465,196 (+)Ensembl
RefSeq Acc Id: NM_001190458   ⟹   NP_001177387
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389273,046 - 465,255 (+)NCBI
GRCh379214,865 - 465,259 (+)ENTREZGENE
HuRef9168,609 - 417,080 (+)ENTREZGENE
CHM1_19273,498 - 464,907 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001193536   ⟹   NP_001180465
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389273,046 - 465,255 (+)NCBI
GRCh379214,865 - 465,259 (+)ENTREZGENE
HuRef9168,609 - 417,080 (+)ENTREZGENE
CHM1_19273,498 - 464,907 (+)NCBI
Sequence:
RefSeq Acc Id: NM_203447   ⟹   NP_982272
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389214,865 - 465,255 (+)NCBI
GRCh379214,865 - 465,259 (+)NCBI
Build 369263,048 - 455,255 (+)NCBI Archive
HuRef9168,609 - 417,080 (+)ENTREZGENE
CHM1_19215,319 - 464,907 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011518045   ⟹   XP_011516347
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389211,296 - 465,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011518046   ⟹   XP_011516348
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389273,050 - 465,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011518047   ⟹   XP_011516349
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389215,303 - 465,255 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011518048   ⟹   XP_011516350
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389276,999 - 465,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011518049   ⟹   XP_011516351
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389366,202 - 465,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017015173   ⟹   XP_016870662
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389211,297 - 465,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017015174   ⟹   XP_016870663
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389276,999 - 465,260 (+)NCBI
Sequence: