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Gene: Axl (AXL receptor tyrosine kinase) Mus musculus
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Symbol: Axl
Name: AXL receptor tyrosine kinase
Description: Exhibits protein heterodimerization activity. Involved in several processes, including animal organ development; myeloid cell homeostasis; and positive regulation of protein kinase B signaling. Predicted to localize to several cellular components, including the actin cytoskeleton; cell surface; and host cell surface. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and visual system. Orthologous to human AXL (AXL receptor tyrosine kinase); PARTICIPATES IN Gas6 - Axl signaling axis; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adhesion-related kinase; AI323647; Ark; Tyro7; tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog
Orthologs:
Homo sapiens (human) : AXL (AXL receptor tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Axl (Axl receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Axl (AXL receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : AXL (AXL receptor tyrosine kinase)
Canis lupus familiaris (dog) : AXL (AXL receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Axl (AXL receptor tyrosine kinase)
Sus scrofa (pig) : AXL (AXL receptor tyrosine kinase)
more info ...
Related Pseudogenes: Gm18404  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38725,756,500 - 25,788,924 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37726,542,292 - 26,573,560 (-)NCBIGRCm37mm9NCBIm37
MGSCv36725,466,033 - 25,497,301 (-)NCBImm8
Celera720,365,412 - 20,397,704 (-)NCBICelera
Cytogenetic Map7 A3NCBI
cM Map714.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Axl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323765
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.