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Gene: Srgn (serglycin) Mus musculus
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Symbol: Srgn
Name: serglycin
Description: Predicted to have collagen binding activity. Involved in several processes, including negative regulation of cytokine secretion; protein localization to secretory granule; and regulation of postsynapse organization. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; mast cell granule; and postsynaptic specialization, intracellular component. Predicted to colocalize with the Golgi membrane. Is expressed in several structures, including autopod; central nervous system; liver; parietal endoderm; and thymus primordium. Orthologous to human SRGN (serglycin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: gp600; mastocytoma proteoglycan core protein; Prg; Prg1; proteoglycan 1, secretory granule; proteoglycan, secretory granule; secretory granule proteoglycan core protein; Sgc
Orthologs:
Homo sapiens (human) : SRGN (serglycin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Srgn (serglycin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srgn (serglycin)
Pan paniscus (bonobo/pygmy chimpanzee) : SRGN (serglycin)
Canis lupus familiaris (dog) : SRGN (serglycin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srgn (serglycin)
Sus scrofa (pig) : SRGN (serglycin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381062,493,833 - 62,527,445 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371061,957,176 - 61,970,503 (-)NCBIGRCm37mm9NCBIm37
MGSCv361061,889,785 - 61,903,112 (-)NCBImm8
Celera1063,596,893 - 63,610,808 (-)NCBICelera
Cytogenetic Map10 B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Srgn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550179
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.