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Gene: Fah (fumarylacetoacetate hydrolase) Mus musculus
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Symbol: Fah
Name: fumarylacetoacetate hydrolase
RGD ID: 62225
Description: Exhibits fumarylacetoacetase activity. Involved in arginine catabolic process. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skeleton. Used to study tyrosinemia type I. Human ortholog(s) of this gene implicated in tyrosinemia type I. Orthologous to human FAH (fumarylacetoacetate hydrolase); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-diketonase; FAA; fumarylacetoacetase; sw; swst
Orthologs:
Homo sapiens (human) : FAH (fumarylacetoacetate hydrolase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fah (fumarylacetoacetate hydrolase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fah (fumarylacetoacetate hydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : FAH (fumarylacetoacetate hydrolase)
Canis lupus familiaris (dog) : FAH (fumarylacetoacetate hydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fah (fumarylacetoacetate hydrolase)
Sus scrofa (pig) : FAH (fumarylacetoacetate hydrolase)
Chlorocebus sabaeus (African green monkey) : FAH (fumarylacetoacetate hydrolase)
Heterocephalus glaber (naked mole-rat) : Fah (fumarylacetoacetate hydrolase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl784,585,159 - 84,606,722 (-)EnsemblGRCm38mm10GRCm38
GRCm38784,585,159 - 84,605,942 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37791,733,669 - 91,754,452 (-)NCBIGRCm37mm9NCBIm37
MGSCv36784,461,355 - 84,481,937 (-)NCBImm8
Celera781,987,620 - 82,008,470 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fah
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62225
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.