FAH (fumarylacetoacetate hydrolase)

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Gene: FAH (fumarylacetoacetate hydrolase) Pan paniscus

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Symbol:

FAH

Name:

fumarylacetoacetate hydrolase

RGD ID:

11905178

Description:

ENCODES a protein that exhibits DNA binding (inferred); fumarylacetoacetase activity (inferred); hydrolase activity (inferred); INVOLVED IN arginine catabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; ASSOCIATED WITH beta-mannosidosis (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

fumarylacetoacetase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	69,406,972 - 69,440,591 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	73,571,710 - 73,605,514 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	59,121,657 - 59,155,229 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	78,081,523 - 78,115,169 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	78,048,571 - 78,115,098 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

beta-mannosidosis (ISO)

Bloom syndrome (ISO)

colorectal cancer (ISO)

COVID-19 (ISO)

genetic disease (ISO)

hepatoblastoma (ISO)

hypertension (ISO)

liver cirrhosis (ISO)

liver disease (ISO)

Liver Failure (ISO)

tyrosinemia (ISO)

tyrosinemia type I (ISO)

tyrosinemia type II (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arginine catabolic process (ISO)

aromatic amino acid metabolic process (IEA)

homogentisate catabolic process (IEA)

L-phenylalanine catabolic process (IEA)

protein targeting to peroxisome (IEA)

tyrosine catabolic process (IEA)

Molecular Function

DNA binding (IEA)

fumarylacetoacetase activity (IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

polyubiquitin modification-dependent protein binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alkaptonuria pathway (ISO)

disulfiram pharmacodynamics pathway (ISO)

dopamine beta-hydroxylase deficiency pathway (ISO)

hawkinsinuria pathway (ISO)

phenylketonuria pathway (ISO)

tyrosine metabolic pathway (ISO)

tyrosinemia type I pathway (ISO)

tyrosinemia type II pathway (ISO)

tyrosinemia type III pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FAH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	69,406,972 - 69,440,591 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	73,571,710 - 73,605,514 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	59,121,657 - 59,155,229 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	78,081,523 - 78,115,169 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	78,048,571 - 78,115,098 (+)	Ensembl	panpan1.1		panPan2

FAH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	80,152,789 - 80,186,949 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	80,152,490 - 80,186,946 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	80,445,131 - 80,479,291 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	78,232,396 - 78,265,737 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	78,232,395 - 78,265,737	NCBI
Celera	15	57,382,789 - 57,416,130 (+)	NCBI		Celera
Cytogenetic Map	15	q25.1	NCBI
HuRef	15	57,208,400 - 57,236,922 (+)	NCBI		HuRef
CHM1_1	15	80,563,191 - 80,596,880 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	78,016,209 - 78,050,378 (+)	NCBI		T2T-CHM13v2.0

Fah
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	84,234,367 - 84,255,150 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	84,234,367 - 84,255,930 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	84,585,159 - 84,605,942 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	84,585,159 - 84,606,722 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	91,733,669 - 91,754,452 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	84,461,355 - 84,481,937 (-)	NCBI		MGSCv36	mm8
Celera	7	81,987,620 - 82,008,470 (-)	NCBI		Celera
Cytogenetic Map	7	D3	NCBI
cM Map	7	48.36	NCBI

Fah
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	147,957,931 - 147,980,708 (-)	NCBI		GRCr8
mRatBN7.2	1	138,548,830 - 138,571,599 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	138,548,834 - 138,571,505 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	146,501,260 - 146,524,074 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	153,670,263 - 153,693,077 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	146,545,471 - 146,568,281 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	146,713,663 - 146,736,339 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	146,713,676 - 146,736,261 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	147,640,316 - 147,662,920 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	140,851,975 - 140,876,187 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	140,930,382 - 140,954,593 (-)	NCBI
Celera	1	130,566,888 - 130,589,532 (-)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

Fah
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955533	904,295 - 921,730 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955533	904,294 - 921,730 (+)	NCBI	ChiLan1.0	ChiLan1.0

FAH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	57,300,422 - 57,326,546 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	57,300,441 - 57,326,486 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	59,958,877 - 59,985,019 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	57,726,930 - 57,753,060 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	57,702,957 - 57,753,270 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	57,232,805 - 57,258,945 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	57,439,515 - 57,465,634 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	57,786,369 - 57,812,502 (-)	NCBI		UU_Cfam_GSD_1.0

Fah
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	120,292,223 - 120,326,410 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	38,140,273 - 38,174,702 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	38,140,324 - 38,174,472 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	49,047,902 - 49,087,783 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	49,047,833 - 49,087,790 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	54,556,153 - 54,596,338 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	3,223,327 - 3,259,367 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	3,223,079 - 3,258,657 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	138,616,632 - 138,652,526 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fah
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624941	1,039,429 - 1,056,568 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624941	1,039,389 - 1,056,568 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008963085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008963086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034939261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034939262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000064600 ⟹ ENSPPAP00000041674

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	78,048,571 - 78,067,171 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000064602 ⟹ ENSPPAP00000041676

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	78,048,571 - 78,059,573 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000064607 ⟹ ENSPPAP00000041681

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	78,059,414 - 78,114,952 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000064610 ⟹ ENSPPAP00000041684

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	78,081,523 - 78,115,098 (+)	Ensembl

RefSeq Acc Id:

XM_008963085 ⟹ XP_008961333

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	69,406,972 - 69,440,591 (+)	NCBI
NHGRI_mPanPan1	15	73,571,712 - 73,605,514 (+)	NCBI
Mhudiblu_PPA_v0	15	59,121,657 - 59,155,229 (+)	NCBI
PanPan1.1	15	78,081,523 - 78,115,169 (+)	NCBI

Sequence:

show sequence

GGCGAGGCGGGGCTCTGGAAGGGCGGGCGAGACTGTGGAGGACCTGGAGCTGGCGGGGGTCAGG
GTAGGGGGGAGGGGCAGGGTTCGGGTTCGGGGCGGGGTGTTCACGGTGAGACCAAAAGTCAGGC
CCGCAGCCGTGCCGGGTGCTCTCCAGCATGTCCTTCATCCCGGTGGCCGAGGATTCCGACTTCC
CCATCCACAACCTGCCCTACGGCGTCTTCTCGACCAGAGGCGACCCAAGACCAAGGATAGGTGT
GGCCATTGGCGACCAGATCCTGGACCTCAGCATCATCAAGCACCTCTTTACTGGTCCTGTCCTC
TCCAAACACCAGGATGTCTTCAATCAGCCTACACTCAACAGCTTCATGGGCCTGGGTCAGGCTG
CCTGGAAGGAGGCGAGAGTGTTCCTGCAGAACTTGCTGTCTGTGAGCCAAGCCAGGCTCAGAGA
TGACACCGAACTTCGGAAGGGTGCATTCATCTCCCAGGCTTCTGCCACGATGCACCTTCCAGCC
GCCATAGGAGACTACACAGACTTCTATTCCTCTCGGCAGCATGCTACCAACGTCGGAATCATGT
TCAGGGACAAGGAGAATGCATTGATGCCAAATTGGCTGCACTTACCAGTGGGCTACCATGGCCG
TGCCTCCTCCGTCGTGGTGTCTGGCACCCCAATCCGAAGGCCCATGGGACAGATGAAACCTGAT
GACTCTAAGCCTCCCGTATATGGTGCCTGCAAGCTCTTGGACATGGAGCTGGAAATGGCTTTTT
TTGTAGGCCCTGGAAACAGATTGGGAGAGCCGATCCCCATTTCCAAGGCCCATGAGCACATTTT
TGGAATGGTCCTTATGAACGACTGGAGTGCACGAGACATTCAGAAGTGGGAGTATGTCCCTCTC
GGGCCATTCCTTGGGAAGAGTTTTGGGACCACTATCTCTCCATGGGTGGTGCCCATGGATGCTC
TCATGCCCTTTGCTGTGCCCAACCCGAAGCAGGACCCCAGGCCCCTGCCGTATCTGTGCCATGA
CGAGCCCTACACATTTGACATCAACCTCTCTGTTAACCTGAAAGGAGAAGGAATGAGCCAGGCG
GCTACCATATGCAAGTCCAATTTTAAGTACATGTACTGGACGATGCTGCAGCAGCTCACTCACC
ACTCTGTCAACGGCTGCAACCTGCGGCCGGGGGACCTCCTGGCTTCTGGGACCATCAGTGGGCC
GGAGCCAGAAAACTTCGGCTCCATGTTGGAACTGTCGTGGAAGGGAACGAAGCCCATAGACCTG
GGGAATGGTCAGACCAGGAAGTTTCTGCTGGACGGGGATGAAGTCATCATAACAGGGTACTGCC
AGGGGGATGGTTACCGCATCGGCTTTGGCCAGTGTGCTGGAAAAGTGCTGCCTGCTCTCCTGCC
ATCATGAGATTTTCTCTGCTCTTCTGGAAACAAAGGGCTCAAGCACCCCTTTCAACCCTGTGAC
TGGGGTCCTCCCTCGGGCTGTAGGCCTGGTCCGCCATTCAGTGACAAATAAAGCCATTGTGCTC
TGAGGCCTGCACTGCCGCAGATGCAGCTGTGCCCACTTATGATCGTGATTTGATCCAGTGGGTC
AAGGTGTGTAAAGCCTCCCTGCCAGATATTCA

hide sequence

RefSeq Acc Id:

XM_008963086 ⟹ XP_008961334

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	69,406,976 - 69,440,591 (+)	NCBI
NHGRI_mPanPan1	15	73,571,710 - 73,605,514 (+)	NCBI
Mhudiblu_PPA_v0	15	59,121,658 - 59,155,229 (+)	NCBI
PanPan1.1	15	78,081,538 - 78,115,098 (+)	NCBI

Sequence:

show sequence

TGGAAGGGCGGGCGAGACTGTGGAGGACCTGGAGCTGGCGGGGGTCAGGGCCCGCAGCCGTGCC
GGGTGCTCTCCAGCATGTCCTTCATCCCGGTGGCCGAGGATTCCGACTTCCCCATCCACAACCT
GCCCTACGGCGTCTTCTCGACCAGAGGCGACCCAAGACCAAGGATAGGTGTGGCCATTGGCGAC
CAGATCCTGGACCTCAGCATCATCAAGCACCTCTTTACTGGTCCTGTCCTCTCCAAACACCAGG
ATGTCTTCAATCAGCCTACACTCAACAGCTTCATGGGCCTGGGTCAGGCTGCCTGGAAGGAGGC
GAGAGTGTTCCTGCAGAACTTGCTGTCTGTGAGCCAAGCCAGGCTCAGAGATGACACCGAACTT
CGGAAGGGTGCATTCATCTCCCAGGCTTCTGCCACGATGCACCTTCCAGCCGCCATAGGAGACT
ACACAGACTTCTATTCCTCTCGGCAGCATGCTACCAACGTCGGAATCATGTTCAGGGACAAGGA
GAATGCATTGATGCCAAATTGGCTGCACTTACCAGTGGGCTACCATGGCCGTGCCTCCTCCGTC
GTGGTGTCTGGCACCCCAATCCGAAGGCCCATGGGACAGATGAAACCTGATGACTCTAAGCCTC
CCGTATATGGTGCCTGCAAGCTCTTGGACATGGAGCTGGAAATGGCTTTTTTTGTAGGCCCTGG
AAACAGATTGGGAGAGCCGATCCCCATTTCCAAGGCCCATGAGCACATTTTTGGAATGGTCCTT
ATGAACGACTGGAGTGCACGAGACATTCAGAAGTGGGAGTATGTCCCTCTCGGGCCATTCCTTG
GGAAGAGTTTTGGGACCACTATCTCTCCATGGGTGGTGCCCATGGATGCTCTCATGCCCTTTGC
TGTGCCCAACCCGAAGCAGGACCCCAGGCCCCTGCCGTATCTGTGCCATGACGAGCCCTACACA
TTTGACATCAACCTCTCTGTTAACCTGAAAGGAGAAGGAATGAGCCAGGCGGCTACCATATGCA
AGTCCAATTTTAAGTACATGTACTGGACGATGCTGCAGCAGCTCACTCACCACTCTGTCAACGG
CTGCAACCTGCGGCCGGGGGACCTCCTGGCTTCTGGGACCATCAGTGGGCCGGAGCCAGAAAAC
TTCGGCTCCATGTTGGAACTGTCGTGGAAGGGAACGAAGCCCATAGACCTGGGGAATGGTCAGA
CCAGGAAGTTTCTGCTGGACGGGGATGAAGTCATCATAACAGGGTACTGCCAGGGGGATGGTTA
CCGCATCGGCTTTGGCCAGTGTGCTGGAAAAGTGCTGCCTGCTCTCCTGCCATCATGAGATTTT
CTCTGCTCTTCTGGAAACAAAGGGCTCAAGCACCCCTTTCAACCCTGTGACTGGGGTCCTCCCT
CGGGCTGTAGGCCTGGTCCGCCATTCAGTGACAAATAAAGCCATTGTGCTCTGAGGCCTGCACT
GCCGCAGATGCA

hide sequence

RefSeq Acc Id:

XM_063596870 ⟹ XP_063452940

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	69,406,972 - 69,440,591 (+)	NCBI

RefSeq Acc Id:

XM_063596871 ⟹ XP_063452941

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	69,406,976 - 69,440,591 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008961333	(Get FASTA)	NCBI Sequence Viewer
	XP_008961334	(Get FASTA)	NCBI Sequence Viewer
	XP_063452940	(Get FASTA)	NCBI Sequence Viewer
	XP_063452941	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000041676.1
	ENSPPAP00000041681.1
	ENSPPAP00000041684.1

RefSeq Acc Id:	XP_008961333 ⟸ XM_008963085
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CIB9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQ PTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKGAFISQASATMHLPAAIGDYTDFY SSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGA CKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFG TTISPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFK YMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFL LDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS hide sequence

RefSeq Acc Id:	XP_008961334 ⟸ XM_008963086
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CIB9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQ PTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKGAFISQASATMHLPAAIGDYTDFY SSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGA CKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFG TTISPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFK YMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFL LDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS hide sequence

Ensembl Acc Id:

ENSPPAP00000041681 ⟸ ENSPPAT00000064607

Ensembl Acc Id:

ENSPPAP00000041684 ⟸ ENSPPAT00000064610

Ensembl Acc Id:

ENSPPAP00000041676 ⟸ ENSPPAT00000064602

Ensembl Acc Id:

ENSPPAP00000041674 ⟸ ENSPPAT00000064600

RefSeq Acc Id:	XP_063452940 ⟸ XM_063596870
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063452941 ⟸ XM_063596871
- Peptide Label:	isoform X1

Protein Domains

A20-type Fumarylacetoacetase N-terminal Fumarylacetoacetase-like C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000043437	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000064602.1	UniProtKB/TrEMBL
	ENSPPAT00000064607.1	UniProtKB/TrEMBL
	ENSPPAT00000064610.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.4770	UniProtKB/TrEMBL
	2.30.30.230	UniProtKB/TrEMBL
	3.90.850.10	UniProtKB/TrEMBL
	4.10.1110.10	UniProtKB/TrEMBL
InterPro	AN1-like_Znf	UniProtKB/TrEMBL
	AN1_A20_ZnFinger	UniProtKB/TrEMBL
	Fumarylacetoacetase	UniProtKB/TrEMBL
	Fumarylacetoacetase-like_C	UniProtKB/TrEMBL
	Fumarylacetoacetase_C_sf	UniProtKB/TrEMBL
	Fumarylacetoacetase_N	UniProtKB/TrEMBL
	Fumarylacetoacetase_N_sf	UniProtKB/TrEMBL
	Znf_A20	UniProtKB/TrEMBL
KEGG Report	pps:100969245	UniProtKB/TrEMBL
NCBI Gene	FAH	ENTREZGENE
PANTHER	AN1-TYPE ZINC FINGER PROTEIN	UniProtKB/TrEMBL
	AN1-TYPE ZINC FINGER PROTEIN 6	UniProtKB/TrEMBL
	FUMARYLACETOACETASE	UniProtKB/TrEMBL
	PTHR43069	UniProtKB/TrEMBL
Pfam	FAA_hydrolase	UniProtKB/TrEMBL
	FAA_hydrolase_N	UniProtKB/TrEMBL
	zf-A20	UniProtKB/TrEMBL
PROSITE	ZF_A20	UniProtKB/TrEMBL
SMART	ZnF_A20	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
	SSF118310	UniProtKB/TrEMBL
	SSF56529	UniProtKB/TrEMBL
	SSF63433	UniProtKB/TrEMBL
UniProt	A0A2R9CI90_PANPA	UniProtKB/TrEMBL
	A0A2R9CI95_PANPA	UniProtKB/TrEMBL
	A0A2R9CIB9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB