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Gene: Polg2 (polymerase (DNA directed), gamma 2, accessory subunit) Mus musculus
Symbol: Polg2
Name: polymerase (DNA directed), gamma 2, accessory subunit
RGD ID: 1312979
Description: Exhibits DNA-directed DNA polymerase activity and identical protein binding activity. Involved in in utero embryonic development; mitochondrion organization; and respiratory electron transport chain. Localizes to mitochondrion. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 and mitochondrial DNA depletion syndrome. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase subunit gamma-2, mitochondrial; mitochondrial DNA polymerase accessory subunit; mitochondrial polymerase gamma 2; mtPolB; p55; polG-beta; polymerase, gamma 2
Homo sapiens (human) : POLG2 (DNA polymerase gamma 2, accessory subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Polg2 (DNA polymerase gamma 2, accessory subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polg2 (DNA polymerase gamma 2, accessory subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Canis lupus familiaris (dog) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polg2 (DNA polymerase gamma 2, accessory subunit)
Sus scrofa (pig) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Chlorocebus sabaeus (African green monkey) : POLG2 (DNA polymerase gamma 2, accessory subunit)
Heterocephalus glaber (naked mole-rat) : Polg2 (DNA polymerase gamma 2, accessory subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11106,768,253 - 106,779,537 (-)EnsemblGRCm38mm10GRCm38
GRCm3811106,768,204 - 106,779,537 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,629,518 - 106,640,851 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,584,396 - 106,595,532 (-)NCBImm8
Celera11118,499,425 - 118,510,748 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Polg2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312979
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.