Fbp1 (fructose bisphosphatase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fbp1 (fructose bisphosphatase 1) Mus musculus
Analyze
Symbol: Fbp1
Name: fructose bisphosphatase 1
RGD ID: 731473
MGI Page MGI
Description: Enables fructose 1,6-bisphosphate 1-phosphatase activity. Involved in gluconeogenesis. Predicted to be located in extracellular space and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; cerebral cortex; facial bone primordium; ganglia; and genitourinary system. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 3; Fbp; Fbp-; Fbp-2; Fbp2; Fbp3; FBPase 1; FBPase 3; FBPase brain isoform; FBPase liver; fructose bisphosphatase 3; fructose-1,6-bisphosphatase 1; fructose-1,6-bisphosphatase isozyme 3; liver FBPase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391363,012,567 - 63,036,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1363,012,567 - 63,036,096 (-)EnsemblGRCm39 Ensembl
GRCm381362,864,753 - 62,888,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1362,864,753 - 62,888,282 (-)EnsemblGRCm38mm10GRCm38
MGSCv371362,966,113 - 62,989,596 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361362,874,376 - 62,897,859 (-)NCBIMGSCv36mm8
Celera1364,525,124 - 64,552,462 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1332.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-benzylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsenous acid  (EXP,ISO)
ATP  (EXP)
benzbromarone  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-D-fructofuranose 2,6-bisphosphate  (EXP)
bifenthrin  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlorpromazine  (ISO)
chromium trinitrate  (EXP)
chromium(6+)  (EXP)
chrysin  (ISO)
cisplatin  (ISO)
citronellol  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucopyranose 6-phosphate  (EXP)
diarsenic trioxide  (EXP,ISO)
Dibutyl phosphate  (ISO)
diethyl maleate  (ISO)
dimethylarsinic acid  (EXP)
elemental selenium  (EXP)
endosulfan  (ISO)
enzyme inhibitor  (EXP)
fipronil  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
fructose  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gentamycin  (ISO)
glyceraldehyde 3-phosphate  (EXP)
glycidyl methacrylate  (ISO)
glyphosate  (EXP)
hydrazine  (ISO)
inulin  (EXP)
isotretinoin  (ISO)
kaempferol  (ISO)
L-ascorbic acid  (EXP)
L-ethionine  (ISO)
lipopolysaccharide  (ISO)
luteolin  (ISO)
mangiferin  (EXP)
metformin  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (EXP)
Muraglitazar  (ISO)
myricetin  (ISO)
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide  (EXP)
N-nitrosomorpholine  (ISO)
naphthalene  (EXP)
nitrofen  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
omeprazole  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
selenic acid  (EXP)
selenium atom  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chlorate  (ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
succimer  (ISO)
tamibarotene  (ISO)
taurine  (EXP)
Tesaglitazar  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (EXP,ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vanillin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (IBA,ISS)
extracellular space  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
hypoglycemia  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Identification of a genetic mutation in a family with fructose-1,6- bisphosphatase deficiency. Kikawa Y, etal., Biochem Biophys Res Commun. 1995 May 25;210(3):797-804.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin. Song S, etal., Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E275-82.
12. PROPERTIES OF PHOSPHOFRUCTOKINASE FROM RAT LIVER AND THEIR RELATION TO THE CONTROL OF GLYCOLYSIS AND GLUCONEOGENESIS. UNDERWOOD AH and NEWSHOLME EA, Biochem J. 1965 Jun;95:868-75.
13. Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in isolated perfused rat liver in response to glucose, fructose and lactate. Wimhurst JM and Manchester KL, Biochem J. 1973 May;134(1):143-56.
14. The expression of FBP1 after traumatic brain injury and its role in astrocyte proliferation. Zhao W, etal., J Mol Neurosci. 2013 Nov;51(3):687-94. doi: 10.1007/s12031-013-0049-x.
Additional References at PubMed
PMID:2996484   PMID:9106734   PMID:10349636   PMID:10773464   PMID:11042159   PMID:11076861   PMID:11250076   PMID:11371557   PMID:12477932   PMID:14668353   PMID:14681479   PMID:15172686  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:16497803   PMID:16919269   PMID:17309103   PMID:17937387   PMID:18287559   PMID:19334288   PMID:19881551   PMID:20719858   PMID:21267068  
PMID:21386911   PMID:21491542   PMID:21873635   PMID:22057438   PMID:22990596   PMID:23260145   PMID:23362348   PMID:26220403   PMID:27215380   PMID:27689697   PMID:27760309   PMID:28245920  
PMID:28901488   PMID:30033198   PMID:30150719   PMID:32325033   PMID:32367049   PMID:33737325   PMID:34363719   PMID:36000567   PMID:36964915   PMID:37084733   PMID:37142076   PMID:37802078  
PMID:37908738   PMID:38834617  


Genomics

Comparative Map Data
Fbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391363,012,567 - 63,036,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1363,012,567 - 63,036,096 (-)EnsemblGRCm39 Ensembl
GRCm381362,864,753 - 62,888,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1362,864,753 - 62,888,282 (-)EnsemblGRCm38mm10GRCm38
MGSCv371362,966,113 - 62,989,596 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361362,874,376 - 62,897,859 (-)NCBIMGSCv36mm8
Celera1364,525,124 - 64,552,462 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1332.74NCBI
FBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38994,603,133 - 94,640,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl994,603,133 - 94,640,249 (-)EnsemblGRCh38hg38GRCh38
GRCh37997,365,415 - 97,402,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36996,405,236 - 96,441,624 (-)NCBINCBI36Build 36hg18NCBI36
Build 34994,444,977 - 94,481,358NCBI
Celera967,806,446 - 67,843,550 (-)NCBICelera
Cytogenetic Map9q22.32NCBI
HuRef966,974,069 - 67,011,150 (-)NCBIHuRef
CHM1_1997,511,867 - 97,548,958 (-)NCBICHM1_1
T2T-CHM13v2.09106,772,462 - 106,809,573 (-)NCBIT2T-CHM13v2.0
Fbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8172,212,941 - 2,235,749 (+)NCBIGRCr8
mRatBN7.2172,207,271 - 2,230,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl172,208,031 - 2,230,071 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx172,226,670 - 2,248,706 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0173,769,275 - 3,791,309 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,224,130 - 2,246,168 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.017396,175 - 417,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl17396,180 - 417,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.017391,323 - 412,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,795,717 - 7,818,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,795,716 - 7,818,038 (+)NCBI
Celera17294,875 - 316,917 (-)NCBICelera
RH 3.4 Map175.6RGD
Cytogenetic Map17p14NCBI
Fbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542221,536,667 - 21,569,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542221,537,337 - 21,569,174 (-)NCBIChiLan1.0ChiLan1.0
FBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21144,817,885 - 44,855,493 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1944,820,279 - 44,857,884 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0965,695,082 - 65,731,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1993,825,142 - 93,860,968 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl993,825,150 - 93,860,968 (-)Ensemblpanpan1.1panPan2
FBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1172,099,886 - 72,125,266 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl172,099,881 - 72,125,224 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha172,861,998 - 72,887,376 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0172,404,539 - 72,429,921 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl172,404,165 - 72,429,918 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1172,215,481 - 72,240,826 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0171,981,002 - 72,006,401 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0172,686,298 - 72,711,910 (+)NCBIUU_Cfam_GSD_1.0
Fbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049444,327,489 - 4,353,383 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366263,555,762 - 3,581,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366263,555,835 - 3,581,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1027,588,570 - 27,622,674 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11027,588,609 - 27,622,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21031,712,560 - 31,829,432 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112108,452,856 - 108,484,052 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12108,453,156 - 108,483,775 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603896,849,781 - 96,881,775 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475316,016,022 - 16,048,104 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475316,019,546 - 16,048,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbp1
568 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:406
Count of miRNA genes:232
Interacting mature miRNAs:269
Transcripts:ENSMUST00000092888, ENSMUST00000134814, ENSMUST00000150013
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse

Markers in Region
Fbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381362,871,197 - 62,871,251UniSTSGRCm38
MGSCv371362,972,557 - 62,972,611UniSTSGRCm37
Celera1364,531,568 - 64,531,622UniSTS
Cytogenetic Map13B3-C1UniSTS
cM Map13 UniSTS
Fbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381362,868,977 - 62,869,049UniSTSGRCm38
MGSCv371362,970,337 - 62,970,409UniSTSGRCm37
Celera1364,529,345 - 64,529,417UniSTS
Cytogenetic Map13B3-C1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001429028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_190570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC156572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC171004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ132693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ242919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ242920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ242921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ242922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000092888   ⟹   ENSMUSP00000090564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1363,012,567 - 63,036,096 (-)Ensembl
GRCm38.p6 Ensembl1362,864,753 - 62,888,282 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134814   ⟹   ENSMUSP00000115703
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1363,020,533 - 63,035,941 (-)Ensembl
GRCm38.p6 Ensembl1362,872,719 - 62,888,127 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150013   ⟹   ENSMUSP00000117146
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1363,012,580 - 63,020,572 (-)Ensembl
GRCm38.p6 Ensembl1362,864,766 - 62,872,758 (-)Ensembl
RefSeq Acc Id: NM_019395   ⟹   NP_062268
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391363,012,567 - 63,036,096 (-)NCBI
GRCm381362,864,753 - 62,888,282 (-)NCBI
MGSCv371362,966,113 - 62,989,596 (-)RGD
Celera1364,525,124 - 64,552,508 (-)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011244488   ⟹   XP_011242790
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391363,012,567 - 63,036,112 (-)NCBI
GRCm381362,864,753 - 62,888,298 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001415957 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415958 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415959 (Get FASTA)   NCBI Sequence Viewer  
  NP_062268 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242790 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH11480 (Get FASTA)   NCBI Sequence Viewer  
  AAH51392 (Get FASTA)   NCBI Sequence Viewer  
  BAB21941 (Get FASTA)   NCBI Sequence Viewer  
  BAE28940 (Get FASTA)   NCBI Sequence Viewer  
  CAA71946 (Get FASTA)   NCBI Sequence Viewer  
  CAB65244 (Get FASTA)   NCBI Sequence Viewer  
  CAB65255 (Get FASTA)   NCBI Sequence Viewer  
  CAB65256 (Get FASTA)   NCBI Sequence Viewer  
  CAB65257 (Get FASTA)   NCBI Sequence Viewer  
  CAB65264 (Get FASTA)   NCBI Sequence Viewer  
  CAB65265 (Get FASTA)   NCBI Sequence Viewer  
  CAB65266 (Get FASTA)   NCBI Sequence Viewer  
  CAB65267 (Get FASTA)   NCBI Sequence Viewer  
  CAB65268 (Get FASTA)   NCBI Sequence Viewer  
  CAB65269 (Get FASTA)   NCBI Sequence Viewer  
  CAB65551 (Get FASTA)   NCBI Sequence Viewer  
  CAB65599 (Get FASTA)   NCBI Sequence Viewer  
  CAB97174 (Get FASTA)   NCBI Sequence Viewer  
  CAB97175 (Get FASTA)   NCBI Sequence Viewer  
  CAB97176 (Get FASTA)   NCBI Sequence Viewer  
  EDL16210 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000090564
  ENSMUSP00000090564.5
  ENSMUSP00000115703.2
  ENSMUSP00000117146.2
GenBank Protein Q9QXD6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062268   ⟸   NM_019395
- UniProtKB: P97323 (UniProtKB/Swiss-Prot),   Q3UEH1 (UniProtKB/Swiss-Prot),   Q9QXD6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242790   ⟸   XM_011244488
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000117146   ⟸   ENSMUST00000150013
Ensembl Acc Id: ENSMUSP00000090564   ⟸   ENSMUST00000092888
Ensembl Acc Id: ENSMUSP00000115703   ⟸   ENSMUST00000134814
Protein Domains
Fructose-1-6-bisphosphatase class 1 C-terminal   Fructose-1-6-bisphosphatase class I N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QXD6-F1-model_v2 AlphaFold Q9QXD6 1-338 view protein structure

Promoters
RGD ID:8680618
Promoter ID:EPDNEW_M18340
Type:initiation region
Name:Fbp1_1
Description:Mus musculus fructose bisphosphatase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18341  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381362,888,161 - 62,888,221EPDNEW
RGD ID:8680620
Promoter ID:EPDNEW_M18341
Type:initiation region
Name:Fbp1_2
Description:Mus musculus fructose bisphosphatase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18340  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381362,888,267 - 62,888,327EPDNEW
RGD ID:6823895
Promoter ID:MM_KWN:14429
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000065308
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361362,974,036 - 62,974,536 (-)MPROMDB
RGD ID:6823896
Promoter ID:MM_KWN:14430
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000065306,   OTTMUST00000065307
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361362,989,236 - 62,989,736 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95492 AgrOrtholog
Ensembl Genes ENSMUSG00000069805 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000092888 ENTREZGENE
  ENSMUST00000092888.11 UniProtKB/Swiss-Prot
  ENSMUST00000134814.2 UniProtKB/TrEMBL
  ENSMUST00000150013.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.190.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FBPase_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBPase_class-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBPase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBPtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fructose_bisphosphatase_AS UniProtKB/Swiss-Prot
KEGG Report mmu:14121 UniProtKB/Swiss-Prot
MGD MGI:95492 ENTREZGENE
NCBI Gene 14121 ENTREZGENE
PANTHER FRUCTOSE-1,6-BISPHOSPHATASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11556 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FBPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBPase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fbp1 PhenoGen
PIRSF FBPtase UniProtKB/Swiss-Prot
  FBPtase_SBPase UniProtKB/Swiss-Prot
PRINTS F16BPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FBPASE UniProtKB/Swiss-Prot
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9Q0T7_MOUSE UniProtKB/TrEMBL
  F16P1_MOUSE UniProtKB/Swiss-Prot
  F6YS63_MOUSE UniProtKB/TrEMBL
  P97323 ENTREZGENE
  Q3UEH1 ENTREZGENE
  Q9QXA8_MOUSE UniProtKB/TrEMBL
  Q9QXA9_MOUSE UniProtKB/TrEMBL
  Q9QXB0_MOUSE UniProtKB/TrEMBL
  Q9QXB1_MOUSE UniProtKB/TrEMBL
  Q9QXB2_MOUSE UniProtKB/TrEMBL
  Q9QXB3_MOUSE UniProtKB/TrEMBL
  Q9QXD6 ENTREZGENE
UniProt Secondary P97323 UniProtKB/Swiss-Prot
  Q3UEH1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Fbp1  fructose bisphosphatase 1  Fbp3  fructose bisphosphatase 3  Data merged from RGD:1608156 737654 PROVISIONAL