Fbp1 (fructose-bisphosphatase 1) - Rat Genome Database

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Gene: Fbp1 (fructose-bisphosphatase 1) Heterocephalus glaber
Analyze
Symbol: Fbp1
Name: fructose-bisphosphatase 1
RGD ID: 18915278
Description: ENCODES a protein that exhibits AMP binding (ortholog); fructose 1,6-bisphosphate 1-phosphatase activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular hyperosmotic salinity response (ortholog); cellular hypotonic salinity response (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructose-1,6-bisphosphatase deficiency pathway; fructosuria pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Baker-Winegrad Disease (ortholog); Colonic Neoplasms (ortholog); FOUND IN extracellular space (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fructose-1,6-bisphosphatase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475316,016,022 - 16,048,104 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475316,019,546 - 16,048,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475316,016,022 - 16,048,104 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475316,019,546 - 16,048,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38994,603,133 - 94,640,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl994,603,133 - 94,640,249 (-)EnsemblGRCh38hg38GRCh38
GRCh37997,365,415 - 97,402,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36996,405,236 - 96,441,624 (-)NCBINCBI36Build 36hg18NCBI36
Build 34994,444,977 - 94,481,358NCBI
Celera967,806,446 - 67,843,550 (-)NCBICelera
Cytogenetic Map9q22.32NCBI
HuRef966,974,069 - 67,011,150 (-)NCBIHuRef
CHM1_1997,511,867 - 97,548,958 (-)NCBICHM1_1
T2T-CHM13v2.09106,772,462 - 106,809,573 (-)NCBIT2T-CHM13v2.0
Fbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391363,012,567 - 63,036,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1363,012,567 - 63,036,096 (-)EnsemblGRCm39 Ensembl
GRCm381362,864,753 - 62,888,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1362,864,753 - 62,888,282 (-)EnsemblGRCm38mm10GRCm38
MGSCv371362,966,113 - 62,989,596 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361362,874,376 - 62,897,859 (-)NCBIMGSCv36mm8
Celera1364,525,124 - 64,552,462 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1332.74NCBI
Fbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8172,212,941 - 2,235,749 (+)NCBIGRCr8
mRatBN7.2172,207,271 - 2,230,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl172,208,031 - 2,230,071 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx172,226,670 - 2,248,706 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0173,769,275 - 3,791,309 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,224,130 - 2,246,168 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.017396,175 - 417,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl17396,180 - 417,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.017391,323 - 412,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,795,717 - 7,818,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,795,716 - 7,818,038 (+)NCBI
Celera17294,875 - 316,917 (-)NCBICelera
RH 3.4 Map175.6RGD
Cytogenetic Map17p14NCBI
Fbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542221,536,667 - 21,569,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542221,537,337 - 21,569,174 (-)NCBIChiLan1.0ChiLan1.0
FBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21144,817,885 - 44,855,493 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1944,820,279 - 44,857,884 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0965,695,082 - 65,731,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1993,825,142 - 93,860,968 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl993,825,150 - 93,860,968 (-)Ensemblpanpan1.1panPan2
FBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1172,099,886 - 72,125,266 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl172,099,881 - 72,125,224 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha172,861,998 - 72,887,376 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0172,404,539 - 72,429,921 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl172,404,165 - 72,429,918 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1172,215,481 - 72,240,826 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0171,981,002 - 72,006,401 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0172,686,298 - 72,711,910 (+)NCBIUU_Cfam_GSD_1.0
Fbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049444,327,489 - 4,353,383 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366263,555,762 - 3,581,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366263,555,835 - 3,581,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1027,588,570 - 27,622,674 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11027,588,609 - 27,622,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21031,712,560 - 31,829,432 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112108,452,856 - 108,484,052 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12108,453,156 - 108,483,775 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603896,849,781 - 96,881,775 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014300   ⟹   ENSHGLP00000014157
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475316,016,022 - 16,048,104 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014301   ⟹   ENSHGLP00000014158
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475316,019,781 - 16,031,172 (-)Ensembl
RefSeq Acc Id: XM_004846079   ⟹   XP_004846136
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475316,019,546 - 16,048,096 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004846136 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04954 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014157
GenBank Protein JAN97549 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004846136   ⟸   XM_004846079
- UniProtKB: A0A0N8ESW0 (UniProtKB/TrEMBL),   G5B6H0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014157   ⟸   ENSHGLT00000014300
Ensembl Acc Id: ENSHGLP00000014158   ⟸   ENSHGLT00000014301


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010114 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014300 ENTREZGENE
Gene3D-CATH 3.40.190.80 UniProtKB/TrEMBL
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/TrEMBL
InterPro FBPase_C_dom UniProtKB/TrEMBL
  FBPase_class-1 UniProtKB/TrEMBL
  FBPase_N UniProtKB/TrEMBL
  FBPtase UniProtKB/TrEMBL
  Fructose_bisphosphatase_AS UniProtKB/TrEMBL
KEGG Report hgl:101708632 UniProtKB/TrEMBL
NCBI Gene Fbp1 ENTREZGENE
PANTHER FRUCTOSE-1,6-BISPHOSPHATASE 1 UniProtKB/TrEMBL
  PTHR11556 UniProtKB/TrEMBL
Pfam FBPase UniProtKB/TrEMBL
  FBPase_C UniProtKB/TrEMBL
PIRSF FBPtase UniProtKB/TrEMBL
  FBPtase_SBPase UniProtKB/TrEMBL
PRINTS F16BPHPHTASE UniProtKB/TrEMBL
PROSITE FBPASE UniProtKB/TrEMBL
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/TrEMBL
UniProt A0A0N8ESW0 ENTREZGENE, UniProtKB/TrEMBL
  G5B6H0 ENTREZGENE, UniProtKB/TrEMBL