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Gene: Klf6 (Kruppel-like factor 6) Mus musculus
Symbol: Klf6
Name: Kruppel-like factor 6
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway and positive regulation of connective tissue replacement. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and peripheral nervous system. Orthologous to human KLF6 (Kruppel like factor 6); INTERACTS WITH 1,1-dichloroethene; 15-deoxy-Delta(12,14)-prostaglandin J2; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI448727; BCD1; C86813; Copeb; core promoter element binding protein; core promoter element-binding protein; CPBP; FM2; FM6; Ierepo1; Ierepo3; immediate early response, erythropoietin 1; Krueppel-like factor 6; R75280; Zf9
Homo sapiens (human) : KLF6 (Kruppel like factor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Klf6 (Kruppel-like factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf6 (Kruppel like factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF6 (Kruppel like factor 6)
Canis lupus familiaris (dog) : KLF6 (Kruppel like factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf6 (Kruppel like factor 6)
Sus scrofa (pig) : KLF6 (Kruppel like factor 6)
Chlorocebus sabaeus (African green monkey) : KLF6 (Kruppel like factor 6)
Heterocephalus glaber (naked mole-rat) : Klf6 (Kruppel like factor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl135,861,482 - 5,870,394 (+)Ensembl
GRCm38135,861,489 - 5,870,393 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37135,860,735 - 5,869,639 (+)NCBIGRCm37mm9NCBIm37
MGSCv36135,860,735 - 5,869,639 (+)NCBImm8
Celera135,806,926 - 5,815,830 (+)NCBICelera
Cytogenetic Map13 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Klf6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553632
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.