Npr3 (natriuretic peptide receptor 3) - Rat Genome Database

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Gene: Npr3 (natriuretic peptide receptor 3) Mus musculus
Analyze
Symbol: Npr3
Name: natriuretic peptide receptor 3
RGD ID: 11008
MGI Page MGI
Description: Predicted to enable several functions, including chloride ion binding activity; peptide receptor activity; and protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and positive regulation of urine volume. Predicted to be located in membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and lung. Used to study bone disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3); PARTICIPATES IN C-type natriuretic peptide signaling pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ANP-C; ANPR-C; atrial natriuretic peptide clearance receptor; atrial natriuretic peptide receptor 3; atrial natriuretic peptide receptor type C; B430320C24Rik; C81222; EF-2; lg; lgj; lon; longjohn; NP; Nppc receptor; NPR-C; stri; strigosus
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391511,839,982 - 11,907,923 (-)NCBIGRCm39mm39
GRCm39 Ensembl1511,839,982 - 11,907,373 (-)Ensembl
GRCm381511,839,896 - 11,907,837 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1511,839,896 - 11,907,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371511,769,651 - 11,835,429 (-)NCBIGRCm37mm9NCBIm37
MGSCv361511,784,621 - 11,850,399 (-)NCBImm8
Celera1511,624,844 - 11,690,388 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
barium(0)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (ISO)
C60 fullerene  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carvedilol  (ISO)
chloroprene  (EXP)
chromium atom  (ISO)
chrysene  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dichloroacetic acid  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
flavonoids  (ISO)
flusilazole  (ISO)
folic acid  (ISO)
fonofos  (ISO)
furan  (ISO)
geldanamycin  (ISO)
genistein  (EXP)
Guanylin  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
methyl salicylate  (ISO)
methylisothiazolinone  (ISO)
N-ethyl-N-nitrosourea  (EXP)
nickel atom  (ISO)
nitrofen  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
peroxynitrous acid  (ISO)
phenformin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium atom  (ISO)
potassium bromate  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rimonabant  (EXP)
rotenone  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
titanium dioxide  (EXP,ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal fat pad morphology  (IAGP)
abnormal adipose tissue distribution  (IAGP)
abnormal adipose tissue morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal bone remodeling  (IAGP)
abnormal bone structure  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal digit morphology  (IEA)
abnormal heart morphology  (IEA)
abnormal interscapular fat pad morphology  (IAGP)
abnormal intervertebral disk development  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal metacarpal bone morphology  (IAGP)
abnormal nucleus pulposus morphology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal sacral vertebrae morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal testis morphology  (IEA)
abnormal thoracic cage morphology  (IAGP)
abnormal urine nucleotide level  (IAGP)
abnormal vertebrae development  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal vertebral column morphology  (IEA)
abnormal vertebral epiphyseal plate morphology  (IAGP)
absent nucleus pulposus  (IAGP)
arachnodactyly  (IAGP)
calcified intervertebral disk  (IAGP)
caudal hemivertebra  (IAGP)
caudal vertebral fusion  (IAGP)
clinodactyly  (IEA)
decreased body weight  (IAGP)
decreased brown fat cell lipid droplet size  (IAGP)
decreased circulating insulin level  (IEA)
decreased epididymal fat pad weight  (IAGP)
decreased inguinal fat pad weight  (IAGP)
decreased interscapular fat pad weight  (IAGP)
decreased retroperitoneal fat pad weight  (IAGP)
decreased total body fat amount  (IAGP)
decreased urine osmolality  (IAGP)
decreased white fat cell size  (IAGP)
dehydration  (IAGP)
delayed bone ossification  (IAGP)
delayed endochondral bone ossification  (IAGP)
domed cranium  (IAGP)
elongated metatarsal bones  (IAGP)
elongated vertebral body  (IAGP)
elongated vertebral column  (IEA)
enlarged heart  (IEA)
hunched posture  (IAGP)
hypotension  (IAGP)
hypovolemia  (IAGP)
increased body length  (IAGP)
increased bone mineral content  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased erythrocyte cell number  (IAGP)
increased hematocrit  (IAGP)
increased hemoglobin content  (IAGP)
increased length of long bones  (IAGP)
increased or absent threshold for auditory brainstem response  (IEA)
increased osteoblast cell number  (IAGP)
increased thoracic vertebrae number  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
kinked tail  (IAGP)
kyphosis  (IAGP)
long tail  (IAGP)
polydipsia  (IAGP)
polyuria  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
reduced fertility  (IAGP)
small testis  (IEA)
small thoracic cage  (IAGP)
thin body  (IAGP)
References

Additional References at PubMed
PMID:1652217   PMID:8620881   PMID:9032278   PMID:9321481   PMID:10349636   PMID:10377427   PMID:10692442   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11788435   PMID:11852232   PMID:12118100   PMID:12226475   PMID:12477932   PMID:14704228   PMID:15191892   PMID:15196958   PMID:15306695   PMID:15328023   PMID:15911073   PMID:16141072  
PMID:16141073   PMID:16284245   PMID:16602821   PMID:17951249   PMID:19243017   PMID:19244276   PMID:19805191   PMID:20403400   PMID:21267068   PMID:21846177   PMID:21915269   PMID:21931791  
PMID:22001395   PMID:22307324   PMID:22960454   PMID:23324181   PMID:23499423   PMID:23979929   PMID:24194600   PMID:24344164   PMID:25860030   PMID:27019112   PMID:27056912   PMID:27740716  
PMID:27959934   PMID:28729659   PMID:28743802   PMID:28990933   PMID:29242602   PMID:29409758   PMID:29688375   PMID:29700121   PMID:30007418   PMID:30239604   PMID:30586761   PMID:30636477  
PMID:31112136   PMID:31255729   PMID:31351040   PMID:31666704   PMID:31943281   PMID:33486984   PMID:33567267  


Genomics

Comparative Map Data
Npr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391511,839,982 - 11,907,923 (-)NCBIGRCm39mm39
GRCm39 Ensembl1511,839,982 - 11,907,373 (-)Ensembl
GRCm381511,839,896 - 11,907,837 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1511,839,896 - 11,907,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371511,769,651 - 11,835,429 (-)NCBIGRCm37mm9NCBIm37
MGSCv361511,784,621 - 11,850,399 (-)NCBImm8
Celera1511,624,844 - 11,690,388 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.83NCBI
NPR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl532,689,070 - 32,791,724 (+)EnsemblGRCh38hg38GRCh38
GRCh38532,689,076 - 32,791,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37532,690,978 - 32,791,826 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36532,747,422 - 32,823,013 (+)NCBINCBI36hg18NCBI36
Build 34532,747,421 - 32,823,009NCBI
Celera532,593,318 - 32,668,888 (+)NCBI
Cytogenetic Map5p13.3NCBI
HuRef532,678,571 - 32,759,879 (+)NCBIHuRef
CHM1_1532,712,833 - 32,793,931 (+)NCBICHM1_1
Npr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2260,865,483 - 60,933,432 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl260,870,594 - 60,932,955 (-)Ensembl
Rnor_6.0261,883,946 - 61,950,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl261,888,950 - 61,949,926 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0282,740,513 - 82,806,584 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4261,278,264 - 61,341,460 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1261,206,496 - 61,269,693 (-)NCBI
Celera257,760,666 - 57,821,249 (+)NCBICelera
Cytogenetic Map2q16NCBI
Npr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542618,491,350 - 18,553,743 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542618,491,350 - 18,559,299 (+)NCBIChiLan1.0ChiLan1.0
NPR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1582,921,035 - 83,004,964 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl582,926,409 - 83,004,964 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0577,542,200 - 77,621,983 (-)NCBIMhudiblu_PPA_v0panPan3
NPR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1474,794,553 - 74,863,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl474,799,857 - 74,862,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha474,429,055 - 74,497,877 (-)NCBI
ROS_Cfam_1.0475,311,739 - 75,380,568 (-)NCBI
UMICH_Zoey_3.1475,049,009 - 75,118,047 (-)NCBI
UNSW_CanFamBas_1.0475,177,562 - 75,246,355 (-)NCBI
UU_Cfam_GSD_1.0475,708,336 - 75,777,195 (-)NCBI
Npr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213223,211,508 - 223,281,564 (+)NCBI
SpeTri2.0NW_0049365188,093,111 - 8,158,862 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1618,842,039 - 18,929,813 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11618,841,540 - 18,929,813 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NPR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1431,984,712 - 32,062,593 (+)NCBI
ChlSab1.1431,984,712 - 32,062,593 (+)NCBI
ChlSab1.1431,984,712 - 32,062,593 (+)NCBI
ChlSab1.1 Ensembl431,986,217 - 32,062,199 (+)Ensembl
Vero_WHO_p1.0NW_02366607122,244,880 - 22,328,902 (+)NCBI
Npr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475921,826,271 - 21,904,928 (-)NCBI

Position Markers
RH127035  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381511,839,949 - 11,840,195UniSTSGRCm38
MGSCv371511,769,704 - 11,769,950UniSTSGRCm37
Celera1511,624,897 - 11,625,140UniSTS
Cytogenetic Map15A1UniSTS
cM Map156.7UniSTS
Whitehead/MRC_RH15125.54UniSTS
Npr3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371511,837,259 - 11,837,501UniSTSGRCm37
Celera1511,692,205 - 11,692,447UniSTS
Cytogenetic Map15A1UniSTS
cM Map156.7UniSTS
cM Map156.7UniSTS
PMC17879P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381511,905,599 - 11,906,150UniSTSGRCm38
MGSCv371511,835,354 - 11,835,905UniSTSGRCm37
Celera1511,690,313 - 11,690,864UniSTS
Cytogenetic Map15A1UniSTS
cM Map156.7UniSTS
PMC22098P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381511,904,894 - 11,905,415UniSTSGRCm38
MGSCv371511,834,649 - 11,835,170UniSTSGRCm37
Celera1511,689,608 - 11,690,129UniSTS
Cytogenetic Map15A1UniSTS
cM Map156.7UniSTS
Npr3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381511,907,504 - 11,907,746UniSTSGRCm38
MGSCv371511,837,259 - 11,837,501UniSTSGRCm37
Celera1511,692,205 - 11,692,447UniSTS
Cytogenetic Map15A1UniSTS
cM Map156.7UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300953Bdt5_mbone density traits 5 (mouse)Not determined15120460347Mouse
1301023Sluc24_msusceptibility to lung cancer 24 (mouse)Not determined15120460347Mouse
1302121Cliff_mcliff drop aversion (mouse)Not determined15120460347Mouse
1301662Faq8_mfluctuating asymmetry QTL 8 (mouse)Not determined15120460347Mouse
5491193Mobq4_mmultigenic obesity QTL 4 (mouse)Not determined15120460347Mouse
4141541Tglq3_mtriglyceride QTL 3 (mouse)Not determined15120460347Mouse
1357459Nhdlq7_mnon-HDL QTL 7 (mouse)Not determined15120460347Mouse
11062069Bpq31_mblood pressure QTL 31 (mouse)15126273109Mouse
4141446Ffaq4_mfree fatty acid QTL 4 (mouse)Not determined127101304Mouse
1300594Eae2_msusceptibility to experimental allergic encephalomyelitis 2 (mouse)Not determined15131218650Mouse
1301136Pgia8_mproteoglycan induced arthritis 8 (mouse)Not determined15321068524388090Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15344490771325689Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined346021278717086Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined346021278717086Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined346021278717086Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15346021278717086Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15346021278717086Mouse
4141358Ath22_matherosclerosis 22 (mouse)Not determined346456637464566Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562040839620528Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15610000038000000Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15610000050900000Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15610000068400000Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15610000071600000Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15610000072600000Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15610000076000000Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15610000076500000Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15610000078800000Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15610000086800000Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15680000045100000Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15690000076000000Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15690000076000000Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15690000084700000Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15720000055400000Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15760000055400000Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15760000059400000Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15810000038900000Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15810000047800000Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927293643448484Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927293643448484Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927293656323454Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927293679590561Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1937
Count of miRNA genes:737
Interacting mature miRNAs:973
Transcripts:ENSMUST00000066529
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA124180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA763613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB007853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF131861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF131862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF131863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF131864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ831432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ832991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY315242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D78175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000066529   ⟹   ENSMUSP00000066737
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1511,839,982 - 11,905,725 (-)Ensembl
GRCm38.p6 Ensembl1511,839,896 - 11,905,639 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226139
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1511,842,346 - 11,891,074 (-)Ensembl
GRCm38.p6 Ensembl1511,842,260 - 11,890,988 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226878
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1511,902,971 - 11,907,287 (-)Ensembl
GRCm38.p6 Ensembl1511,902,885 - 11,907,201 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228489   ⟹   ENSMUSP00000153895
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1511,844,469 - 11,907,373 (-)Ensembl
GRCm38.p6 Ensembl1511,844,383 - 11,907,287 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228603   ⟹   ENSMUSP00000154180
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1511,844,469 - 11,905,760 (-)Ensembl
GRCm38.p6 Ensembl1511,844,383 - 11,905,674 (-)Ensembl
RefSeq Acc Id: NM_001039181   ⟹   NP_001034270
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,905,760 (-)NCBI
GRCm381511,839,896 - 11,905,674 (-)NCBI
MGSCv371511,769,651 - 11,835,429 (-)RGD
Celera1511,624,844 - 11,692,072 (-)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001286395   ⟹   NP_001273324
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,907,457 (-)NCBI
GRCm381511,839,896 - 11,907,371 (-)NCBI
Celera1511,624,844 - 11,692,072 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008728   ⟹   NP_032754
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,905,760 (-)NCBI
GRCm381511,839,896 - 11,905,674 (-)NCBI
MGSCv371511,769,651 - 11,835,429 (-)RGD
Celera1511,624,844 - 11,692,072 (-)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520028   ⟹   XP_006520091
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,907,246 (-)NCBI
GRCm381511,839,896 - 11,907,160 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520030   ⟹   XP_006520093
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,844,471 - 11,904,209 (-)NCBI
GRCm381511,839,896 - 11,903,970 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520031   ⟹   XP_006520094
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,904,768 (-)NCBI
GRCm381511,839,896 - 11,904,684 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248376   ⟹   XP_030104236
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,906,776 (-)NCBI
GRCm381511,839,896 - 11,906,690 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248377   ⟹   XP_030104237
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391511,839,982 - 11,907,923 (-)NCBI
GRCm381511,844,382 - 11,907,837 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032754   ⟸   NM_008728
- Peptide Label: isoform a precursor
- UniProtKB: P70180 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001034270   ⟸   NM_001039181
- Peptide Label: isoform b precursor
- UniProtKB: Q7TMG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273324   ⟸   NM_001286395
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: XP_006520091   ⟸   XM_006520028
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006520094   ⟸   XM_006520031
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006520093   ⟸   XM_006520030
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030104236   ⟸   XM_030248376
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030104237   ⟸   XM_030248377
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000066737   ⟸   ENSMUST00000066529
RefSeq Acc Id: ENSMUSP00000153895   ⟸   ENSMUST00000228489
RefSeq Acc Id: ENSMUSP00000154180   ⟸   ENSMUST00000228603
Protein Domains
ANF_receptor

Promoters
RGD ID:6826281
Promoter ID:MM_KWN:18054
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000066529,   NM_001039181
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361511,834,701 - 11,835,877 (-)MPROMDB
RGD ID:6826282
Promoter ID:MM_KWN:18056
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4
Transcripts:UC007VHG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361511,836,701 - 11,837,201 (-)MPROMDB
RGD ID:8683432
Promoter ID:EPDNEW_M19747
Type:multiple initiation site
Name:Npr3_2
Description:Mus musculus natriuretic peptide receptor 3 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19748  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381511,905,618 - 11,905,678EPDNEW
RGD ID:8683434
Promoter ID:EPDNEW_M19748
Type:single initiation site
Name:Npr3_1
Description:Mus musculus natriuretic peptide receptor 3 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19747  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381511,906,106 - 11,906,166EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97373 AgrOrtholog
Ensembl Genes ENSMUSG00000022206 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000066737 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000153895 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000154180 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066529 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000228489 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000228603 ENTREZGENE, UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANPR/GUC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18162 UniProtKB/Swiss-Prot
MGD MGI:97373 ENTREZGENE
NCBI Gene 18162 ENTREZGENE
Pfam ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Npr3 PhenoGen
PRINTS NATPEPTIDER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANF_RECEPTORS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BPR9_MOUSE UniProtKB/TrEMBL
  ANPRC_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TLF4_MOUSE UniProtKB/TrEMBL
  Q7TMG7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary G3X9E5 UniProtKB/Swiss-Prot
  P97804 UniProtKB/Swiss-Prot
  Q9R025 UniProtKB/Swiss-Prot
  Q9R027 UniProtKB/Swiss-Prot
  Q9R028 UniProtKB/Swiss-Prot