Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dtnb | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of DTNB mRNA | CTD | PMID:22206623 | Dtnb | Mouse | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of DTNB mRNA | CTD | PMID:17555576 | Dtnb | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DTNB mRNA | CTD | PMID:17942748 | Dtnb | Mouse | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of DTNB mRNA | CTD | PMID:17942748 | Dtnb | Mouse | 17beta-estradiol | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of DTNB mRNA | CTD | PMID:26496021 | Dtnb | Mouse | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Dtnb | Mouse | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DTNB mRNA | CTD | PMID:17942748 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTNB mRNA | CTD | PMID:33387578 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DTNB mRNA | CTD | PMID:34747641 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DTNB mRNA | CTD | PMID:21570461 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DTNB mRNA | CTD | PMID:21215274 | Dtnb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTNB mRNA | CTD | PMID:17942748 | Dtnb | Mouse | 2,4-dinitrotoluene | affects expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of DTNB mRNA | CTD | PMID:21346803 | Dtnb | Mouse | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | 3 more ... | CTD | PMID:23196670 | Dtnb | Mouse | acrolein | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DTNB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DTNB mRNA | CTD | PMID:32699268 | Dtnb | Mouse | aflatoxin B1 | affects methylation | ISO | DTNB (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of DTNB intron | CTD | PMID:30157460 | Dtnb | Mouse | all-trans-retinoic acid | decreases expression | ISO | DTNB (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DTNB mRNA | CTD | PMID:33167477 | Dtnb | Mouse | alpha-pinene | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DTNB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DTNB mRNA | CTD | PMID:32699268 | Dtnb | Mouse | alpha-Zearalanol | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of DTNB mRNA | CTD | PMID:35163327 | Dtnb | Mouse | amphetamine | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of DTNB mRNA | CTD | PMID:30779732 | Dtnb | Mouse | aristolochic acid A | decreases expression | ISO | DTNB (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DTNB mRNA | CTD | PMID:33212167 | Dtnb | Mouse | arsenite(3-) | decreases expression | EXP | | 6480464 | arsenite results in decreased expression of DTNB protein | CTD | PMID:37955338 | Dtnb | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of DTNB mRNA] | CTD | PMID:22228805 | Dtnb | Mouse | benzo[a]pyrene | decreases methylation | ISO | DTNB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of DTNB 3' UTR | CTD | PMID:27901495 | Dtnb | Mouse | benzo[a]pyrene | affects methylation | ISO | DTNB (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DTNB intron | CTD | PMID:30157460 | Dtnb | Mouse | benzo[a]pyrene | decreases expression | ISO | DTNB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of DTNB mRNA | CTD | PMID:26238291 | Dtnb | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DTNB (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Dtnb | Mouse | beta-naphthoflavone | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DTNB mRNA | CTD | PMID:18164116 | Dtnb | Mouse | bezafibrate | decreases expression | EXP | | 6480464 | Bezafibrate results in decreased expression of DTNB mRNA | CTD | PMID:18787029 | Dtnb | Mouse | bisphenol A | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of DTNB mRNA | CTD | PMID:26496021 | Dtnb | Mouse | bisphenol A | affects methylation | ISO | DTNB (Homo sapiens) | 6480464 | bisphenol A affects the methylation of DTNB gene | CTD | PMID:31601247 | Dtnb | Mouse | bisphenol A | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DTNB gene | CTD | PMID:31601247 | Dtnb | Mouse | bisphenol A | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DTNB mRNA | CTD | PMID:34947998 | Dtnb | Mouse | bisphenol A | increases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DTNB mRNA | CTD | PMID:25181051 | Dtnb | Mouse | C60 fullerene | increases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | fullerene C60 results in increased expression of DTNB mRNA | CTD | PMID:19167457 | Dtnb | Mouse | cadmium dichloride | decreases expression | ISO | DTNB (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of DTNB mRNA | CTD | PMID:38382870 | Dtnb | Mouse | cadmium dichloride | increases expression | ISO | DTNB (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of DTNB mRNA | CTD | PMID:38568856 | Dtnb | Mouse | calcitriol | increases expression | ISO | DTNB (Homo sapiens) | 6480464 | Calcitriol results in increased expression of DTNB mRNA | CTD | PMID:26485663 | Dtnb | Mouse | CGP 52608 | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DTNB gene] | CTD | PMID:28238834 | Dtnb | Mouse | chlorpyrifos | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Chlorpyrifos results in decreased expression of DTNB mRNA | CTD | PMID:18668222 | Dtnb | Mouse | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of DTNB mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of DTNB mRNA] | CTD | PMID:17585979 | Dtnb | Mouse | dexamethasone | increases expression | EXP | | 6480464 | Dexamethasone results in increased expression of DTNB mRNA | CTD | PMID:22733784 | Dtnb | Mouse | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DTNB mRNA | CTD | PMID:21266533 | Dtnb | Mouse | diuron | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of DTNB mRNA | CTD | PMID:21551480 | Dtnb | Mouse | enzyme inhibitor | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DTNB protein | CTD | PMID:23301498 | Dtnb | Mouse | FR900359 | decreases phosphorylation | ISO | DTNB (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DTNB protein | CTD | PMID:37730182 | Dtnb | Mouse | fulvestrant | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DTNB gene | CTD | PMID:31601247 | Dtnb | Mouse | furan | increases methylation | ISO | Dtnb (Rattus norvegicus) | 6480464 | furan results in increased methylation of DTNB gene | CTD | PMID:22079235 | Dtnb | Mouse | hypochlorous acid | decreases expression | EXP | | 6480464 | Hypochlorous Acid results in decreased expression of DTNB mRNA | CTD | PMID:19376150 | Dtnb | Mouse | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DTNB mRNA | CTD | PMID:36331819 | Dtnb | Mouse | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of DTNB mRNA | CTD | PMID:34813904 | Dtnb | Mouse | methoxychlor | affects methylation | ISO | Dtnb (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of DTNB gene | CTD | PMID:35440735 | Dtnb | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DTNB mRNA | CTD | PMID:18164116 | Dtnb | Mouse | oxaliplatin | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of DTNB mRNA | CTD | PMID:25729387 | Dtnb | Mouse | oxaliplatin | increases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | oxaliplatin results in increased expression of DTNB mRNA | CTD | PMID:25729387 | Dtnb | Mouse | ozone | multiple interactions | ISO | DTNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DTNB mRNA more ... | CTD | PMID:32699268 | Dtnb | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of DTNB mRNA | CTD | PMID:34911549 | Dtnb | Mouse | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of DTNB mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of DTNB mRNA] | CTD | PMID:17585979 | Dtnb | Mouse | paracetamol | increases expression | ISO | DTNB (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DTNB mRNA | CTD | PMID:22230336 and PMID:29067470 | Dtnb | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of DTNB mRNA | CTD | PMID:17562736 | Dtnb | Mouse | PCB138 | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Dtnb | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DTNB mRNA | CTD | PMID:36331819 | Dtnb | Mouse | perfluorooctanoic acid | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of DTNB mRNA | CTD | PMID:35163327 | Dtnb | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of DTNB mRNA | CTD | PMID:18301758 and PMID:23811191 | Dtnb | Mouse | Soman | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Soman results in decreased expression of DTNB mRNA | CTD | PMID:19281266 | Dtnb | Mouse | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of DTNB mRNA | CTD | PMID:17555576 | Dtnb | Mouse | testosterone | increases expression | ISO | DTNB (Homo sapiens) | 6480464 | Testosterone results in increased expression of DTNB mRNA | CTD | PMID:33359661 | Dtnb | Mouse | thioacetamide | decreases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of DTNB mRNA | CTD | PMID:23411599 and PMID:34492290 | Dtnb | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of DTNB promoter | CTD | PMID:35295148 | Dtnb | Mouse | topotecan | multiple interactions | ISO | Dtnb (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of DTNB mRNA | CTD | PMID:25729387 | Dtnb | Mouse | topotecan | increases expression | ISO | Dtnb (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of DTNB mRNA | CTD | PMID:25729387 | Dtnb | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of DTNB mRNA | CTD | PMID:33045310 | Dtnb | Mouse | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of DTNB mRNA | CTD | PMID:35537566 | Dtnb | Mouse | valproic acid | affects expression | ISO | DTNB (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DTNB mRNA | CTD | PMID:25979313 | Dtnb | Mouse | vinclozolin | increases methylation | ISO | Dtnb (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of DTNB gene | CTD | PMID:31079544 and PMID:31682807 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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Mammalian Phenotype
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Cellular Component
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | Beta-dystrobrevin interacts directly with kinesin heavy chain in brain. | Macioce P, etal., J Cell Sci 2003 Dec 1;116(Pt 23):4847-56. |
| 3. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 4. | MGD IEA | MGD IEA |
| 5. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 6. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:9419360 | PMID:9540997 | PMID:9799833 | PMID:10349636 | PMID:10512203 | PMID:10545507 | PMID:10656920 | PMID:10893187 | PMID:10922068 | PMID:10995443 | PMID:11042159 |
| PMID:11076861 | PMID:11316798 | PMID:11585924 | PMID:12477932 | PMID:12923531 | PMID:14610273 | PMID:14688250 | PMID:15782199 | PMID:15840001 | PMID:16141072 | PMID:16141073 | PMID:16288919 |
| PMID:16448387 | PMID:16540561 | PMID:16602821 | PMID:16807372 | PMID:16857187 | PMID:17265465 | PMID:17610895 | PMID:17967808 | PMID:18468998 | PMID:18799693 | PMID:20530487 | PMID:21677750 |
| PMID:21873635 | PMID:22978324 | PMID:32325033 | PMID:32982660 | PMID:35098363 |
Genomics
Comparative Map Data
| Dtnb (Mus musculus - house mouse) |
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| DTNB (Homo sapiens - human) |
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| Dtnb (Rattus norvegicus - Norway rat) |
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| Dtnb (Chinchilla lanigera - long-tailed chinchilla) |
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| DTNB (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DTNB (Canis lupus familiaris - dog) |
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| Dtnb (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DTNB (Sus scrofa - pig) |
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| DTNB (Chlorocebus sabaeus - green monkey) |
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| Dtnb (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Dtnb
5872 total Variants 
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