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Gene: Tapbp (TAP binding protein) Mus musculus
Symbol: Tapbp
Name: TAP binding protein
Description: Predicted to have TAP complex binding activity; TAP1 binding activity; and TAP2 binding activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; defense response; and peptide antigen stabilization. Predicted to localize to Golgi membrane and MHC class I peptide loading complex. Human ortholog(s) of this gene implicated in MHC class I deficiency and severe combined immunodeficiency. Is expressed in several structures, including genitourinary system; hemolymphoid system; nervous system; notochord; and retina. Orthologous to human TAPBP (TAP binding protein); PARTICIPATES IN antigen processing and presentation pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D17Wsu91e; TAP-associated protein; TAP-binding protein; tapasin; TPN; TPSN
Homo sapiens (human) : TAPBP (TAP binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tapbp (TAP binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tapbp (TAP binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TAPBP (TAP binding protein)
Canis lupus familiaris (dog) : TAPBP (TAP binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tapbp (TAP binding protein)
Sus scrofa (pig) : TAPBP (TAP binding protein)
Chlorocebus sabaeus (African green monkey) : TAPBP (TAP binding protein)
Heterocephalus glaber (naked mole-rat) : Tapbp (TAP binding protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1733,915,899 - 33,929,292 (+)EnsemblGRCm38mm10GRCm38
GRCm381733,919,478 - 33,929,290 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,056,423 - 34,066,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,529,932 - 33,539,744 (+)NCBImm8
Celera1736,672,402 - 36,682,204 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tapbp
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735383
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.