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Gene: Tapbp (TAP binding protein) Mus musculus
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Symbol: Tapbp
Name: TAP binding protein
Description: Predicted to have TAP complex binding activity; TAP1 binding activity; and TAP2 binding activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; defense response; and peptide antigen stabilization. Predicted to localize to Golgi membrane and MHC class I peptide loading complex. Human ortholog(s) of this gene implicated in MHC class I deficiency and severe combined immunodeficiency. Is expressed in several structures, including genitourinary system; hemolymphoid system; nervous system; notochord; and retina. Orthologous to human TAPBP (TAP binding protein); PARTICIPATES IN antigen processing and presentation pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D17Wsu91e; TAP-associated protein; TAP-binding protein; tapasin; TPN; TPSN
Orthologs:
Homo sapiens (human) : TAPBP (TAP binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tapbp (TAP binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tapbp (TAP binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TAPBP (TAP binding protein)
Canis lupus familiaris (dog) : TAPBP (TAP binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tapbp (TAP binding protein)
Sus scrofa (pig) : TAPBP (TAP binding protein)
Chlorocebus sabaeus (African green monkey) : TAPBP (TAP binding protein)
Heterocephalus glaber (naked mole-rat) : Tapbp (TAP binding protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1733,915,899 - 33,929,292 (+)EnsemblGRCm38mm10GRCm38
GRCm381733,919,478 - 33,929,290 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,056,423 - 34,066,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,529,932 - 33,539,744 (+)NCBImm8
Celera1736,672,402 - 36,682,204 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tapbp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735383
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.